𝕏

Task 55327398

Name HuVeMOp_20240629201600757918_ORdGradInc_k_25-Drouin_MID_1000-conf_611_1
Workunit 26271728
Created 29 Jun 2024, 18:18:17 UTC
Sent 29 Jun 2024, 20:06:00 UTC
Report deadline 2 Jul 2024, 20:06:00 UTC
Received 30 Jun 2024, 18:59:55 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213754
Run time 2 hours 17 min 3 sec
CPU time 2 hours 14 min 40 sec
Validate state Valid
Credit 43.96
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.59 MB
Peak swap size 6.21 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-Drouin_MID_1000-conf_611.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-Drouin_MID_1000-conf_611_1_r812421391_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-Drouin_MID_1000-conf_611_1_r812421391_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 92.692751
     * GNaL_b in INaL: 0.004844
     * Gto_b in Ito: 0.094759
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033561
     * GKs_b in IKs: 0.001796
     * GK1_b in IK1: 0.160359
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 72.281425
     * GKb_b in IKb: 0.003703
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.024155
     * celltype in environment: 2.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12012713, states[0] = 33.482263, states[40]= -0.000000
Saving checkpoint... 
Iteration: 23863772, states[0] = -94.194889, states[40]= 0.000001
Saving checkpoint... 
Iteration: 35931270, states[0] = -94.333802, states[40]= 0.000001
Saving checkpoint... 
Iteration: 47856990, states[0] = -94.257379, states[40]= 0.000001
Saving checkpoint... 
Iteration: 59880347, states[0] = -94.332867, states[40]= 0.000001
Saving checkpoint... 
Iteration: 71901752, states[0] = -94.384616, states[40]= 0.000001
Saving checkpoint... 
Iteration: 83939609, states[0] = -94.435457, states[40]= 0.000001
Saving checkpoint... 
Iteration: 95969864, states[0] = -94.462547, states[40]= 0.000001
Saving checkpoint... 
Iteration: 108078077, states[0] = 18.127041, states[40]= 0.000298
Saving checkpoint... 
Iteration: 120239706, states[0] = -93.633650, states[40]= 0.000001
Saving checkpoint... 
Iteration: 132234641, states[0] = -93.509836, states[40]= 0.000001
Saving checkpoint... 
Iteration: 144184383, states[0] = -47.701812, states[40]= 0.004037
Saving checkpoint... 
Iteration: 156325528, states[0] = -94.256460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 168460627, states[0] = -94.470292, states[40]= 0.000001
Saving checkpoint... 
Iteration: 180559924, states[0] = 25.372218, states[40]= 0.000023
Saving checkpoint... 
Iteration: 192590268, states[0] = 12.133856, states[40]= 0.001599
Saving checkpoint... 
Iteration: 204525724, states[0] = 33.931330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216516331, states[0] = 33.206119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228556599, states[0] = 26.577316, states[40]= 0.000013
Saving checkpoint... 
Iteration: 240482097, states[0] = -94.472556, states[40]= 0.000001
Saving checkpoint... 
Iteration: 252537266, states[0] = 32.276318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264541313, states[0] = 31.327221, states[40]= 0.000001
Saving checkpoint... 
Iteration: 276541005, states[0] = 31.404592, states[40]= 0.000001
Saving checkpoint... 
Iteration: 288626653, states[0] = -11.538536, states[40]= 0.007335
Saving checkpoint... 
Iteration: 300862053, states[0] = -94.341792, states[40]= 0.000001
Saving checkpoint... 
Iteration: 312906380, states[0] = -94.410250, states[40]= 0.000001
Saving checkpoint... 
Iteration: 324906717, states[0] = -94.409014, states[40]= 0.000001
Saving checkpoint... 
Iteration: 336976292, states[0] = -94.457606, states[40]= 0.000001
Saving checkpoint... 
Iteration: 349084571, states[0] = 14.868232, states[40]= 0.000829
Saving checkpoint... 
Iteration: 360806759, states[0] = -94.157140, states[40]= 0.000001
Saving checkpoint... 
Iteration: 372681394, states[0] = -45.867570, states[40]= 0.004997
Saving checkpoint... 
Iteration: 384711918, states[0] = -73.722540, states[40]= 0.000111
Saving checkpoint... 
Iteration: 396984063, states[0] = -94.452602, states[40]= 0.000001
Saving checkpoint... 
Iteration: 409040179, states[0] = 31.615958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421010116, states[0] = 30.269740, states[40]= -0.000000
Saving checkpoint... 
Iteration: 433100487, states[0] = 6.833304, states[40]= 0.004404
Saving checkpoint... 
Iteration: 445164543, states[0] = -35.094996, states[40]= 0.014149
Saving checkpoint... 
Iteration: 457140778, states[0] = -22.131322, states[40]= 0.015512
Saving checkpoint... 
Iteration: 469403861, states[0] = -94.386430, states[40]= 0.000001
Saving checkpoint... 
Iteration: 481453975, states[0] = -94.427458, states[40]= 0.000001
Saving checkpoint... 
Iteration: 493502371, states[0] = 19.114848, states[40]= 2.884403
Saving checkpoint... 
Iteration: 505512811, states[0] = 31.919015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516896577, states[0] = -94.370980, states[40]= 0.000001
Saving checkpoint... 
Iteration: 528515414, states[0] = 32.957054, states[40]= -0.000000
Saving checkpoint... 
Iteration: 540389731, states[0] = -94.358420, states[40]= 0.000001
Saving checkpoint... 
Iteration: 552333454, states[0] = -94.233758, states[40]= 0.000001
Saving checkpoint... 
Iteration: 564307163, states[0] = -94.131572, states[40]= 0.000001
Saving checkpoint... 
Iteration: 576400753, states[0] = -94.368399, states[40]= 0.000001
Saving checkpoint... 
Iteration: 588404430, states[0] = -94.371253, states[40]= 0.000001
Saving checkpoint... 
Iteration: 600469729, states[0] = -94.419785, states[40]= 0.000001
Saving checkpoint... 
Iteration: 612550299, states[0] = 28.743841, states[40]= 0.000004
Saving checkpoint... 
Iteration: 624441230, states[0] = -94.400351, states[40]= 0.000001
Saving checkpoint... 
Iteration: 636432733, states[0] = -94.392445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 648061852, states[0] = 24.642557, states[40]= 0.000032
Saving checkpoint... 
Iteration: 659924428, states[0] = -94.382353, states[40]= 0.000001
Saving checkpoint... 
Iteration: 671214185, states[0] = -77.139710, states[40]= 0.000067
Saving checkpoint... 
Iteration: 683132937, states[0] = -16.549181, states[40]= 0.007651
Saving checkpoint... 
Iteration: 695159116, states[0] = -32.140707, states[40]= 0.017806
Saving checkpoint... 
Iteration: 706184884, states[0] = -48.401063, states[40]= 0.003745
Saving checkpoint... 
Iteration: 718107870, states[0] = 2.568463, states[40]= 0.007262
Saving checkpoint... 
Iteration: 729972666, states[0] = -94.403973, states[40]= 0.000001
Saving checkpoint... 
Iteration: 741758715, states[0] = -93.782944, states[40]= 0.000001
Saving checkpoint... 
Iteration: 753608544, states[0] = 2.152015, states[40]= 0.007512
Saving checkpoint... 
Iteration: 765522169, states[0] = 34.005240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777428382, states[0] = -94.370239, states[40]= 0.000001
Saving checkpoint... 
Iteration: 789187394, states[0] = -50.285605, states[40]= 0.002996
Saving checkpoint... 
Iteration: 801261461, states[0] = -93.800292, states[40]= 0.000001
Saving checkpoint... 
Iteration: 813172666, states[0] = -39.915718, states[40]= 0.009129
Saving checkpoint... 
Iteration: 825262874, states[0] = -93.809715, states[40]= 0.000001
Saving checkpoint... 
Iteration: 837232087, states[0] = -93.312672, states[40]= 0.000001
Saving checkpoint... 
Iteration: 849156282, states[0] = -30.654037, states[40]= 0.019596
Saving checkpoint... 
Iteration: 861300980, states[0] = -94.062068, states[40]= 0.000001
Saving checkpoint... 
Iteration: 873395515, states[0] = -94.322371, states[40]= 0.000001
Saving checkpoint... 
Iteration: 885464107, states[0] = -94.379567, states[40]= 0.000001
Saving checkpoint... 
Iteration: 897599513, states[0] = 7.400993, states[40]= 0.003968
Saving checkpoint... 
Iteration: 909771475, states[0] = -93.869669, states[40]= 0.000001
Saving checkpoint... 
Iteration: 921874690, states[0] = -94.283735, states[40]= 0.000001
Saving checkpoint... 
Iteration: 934055268, states[0] = 27.086066, states[40]= 0.000010
Saving checkpoint... 
Iteration: 946111546, states[0] = 0.231603, states[40]= 0.008452
Saving checkpoint... 
Iteration: 958267042, states[0] = -93.827580, states[40]= 0.000001
Saving checkpoint... 
Iteration: 970291278, states[0] = -93.995051, states[40]= 0.000001
Saving checkpoint... 
Iteration: 982190372, states[0] = -52.562920, states[40]= 0.002257
Saving checkpoint... 
Iteration: 994306096, states[0] = -94.069244, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1006444494, states[0] = -94.352246, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1018511678, states[0] = 31.331805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030460773, states[0] = -94.358678, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1042423654, states[0] = -94.331095, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1054482543, states[0] = -94.365130, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1066431517, states[0] = -94.334586, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1078294060, states[0] = -93.996432, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1090381343, states[0] = -94.272557, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1102511791, states[0] = 31.402162, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1114504974, states[0] = 25.126326, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1126574941, states[0] = 19.289291, states[40]= 0.000223
Saving checkpoint... 
Iteration: 1138644904, states[0] = -24.555110, states[40]= 0.019787
Saving checkpoint... 
Iteration: 1150413138, states[0] = -94.306422, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1162512773, states[0] = 31.933633, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1174216900, states[0] = -81.558871, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1185961189, states[0] = -94.338167, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1198004946, states[0] = 25.085772, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1210107937, states[0] = 2.583263, states[40]= 0.007103
Saving checkpoint... 
Iteration: 1222088945, states[0] = 12.827080, states[40]= 0.001320
Saving checkpoint... 
Iteration: 1234207475, states[0] = -67.943745, states[40]= 0.000257
Saving checkpoint... 
Iteration: 1246265290, states[0] = -93.774002, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1257849467, states[0] = -94.185000, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1268819396, states[0] = -94.088855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1280785593, states[0] = -93.918837, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1292815952, states[0] = -94.071999, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1304927082, states[0] = -94.299182, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1316838376, states[0] = -94.146760, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1328834235, states[0] = -94.132560, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1340585771, states[0] = 14.363860, states[40]= 0.000898
Saving checkpoint... 
Iteration: 1351832136, states[0] = -94.122853, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1363989918, states[0] = -94.326667, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1376042306, states[0] = 31.135617, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1388133289, states[0] = -16.704857, states[40]= 0.007634
Saving checkpoint... 
Iteration: 1400192133, states[0] = -53.936181, states[40]= 0.001881
Saving checkpoint... 
Iteration: 1412228353, states[0] = -92.767295, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1424223781, states[0] = -90.799717, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1436252944, states[0] = -93.632286, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1448318354, states[0] = -94.060815, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1460428417, states[0] = -94.279785, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1472355429, states[0] = -94.170999, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1484492942, states[0] = -94.311764, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1496550246, states[0] = 28.813046, states[40]= 0.000004
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.187682
 - CaMKt in component CaMK (millimolar): 0.059446
 - cass in component intracellular_ions (millimolar): 0.000108
 - nai in component intracellular_ions (millimolar): 8.630228
 - nass in component intracellular_ions (millimolar): 8.630440
 - ki in component intracellular_ions (millimolar): 141.980613
 - kss in component intracellular_ions (millimolar): 141.980573
 - cansr in component intracellular_ions (millimolar): 3.009551
 - cajsr in component intracellular_ions (millimolar): 2.966514
 - cai in component intracellular_ions (millimolar): 0.000113
 - m in component INa (dimensionless): 0.003889
 - hf in component INa (dimensionless): 0.867046
 - hs in component INa (dimensionless): 0.867034
 - j in component INa (dimensionless): 0.866946
 - hsp in component INa (dimensionless): 0.701826
 - jp in component INa (dimensionless): 0.866876
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.670028
 - hLp in component INaL (dimensionless): 0.383071
 - a in component Ito (dimensionless): 0.000654
 - iF in component Ito (dimensionless): 0.999852
 - iS in component Ito (dimensionless): 0.553566
 - ap in component Ito (dimensionless): 0.000333
 - iFp in component Ito (dimensionless): 0.999852
 - iSp in component Ito (dimensionless): 0.614858
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.868743
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999546
 - jca in component ICaL (dimensionless): 0.999935
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.006788
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.444002
 - xs1 in component IKs (dimensionless): 0.336950
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997519
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
10:58:59 (9124): called boinc_finish(0)

</stderr_txt>
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