Task 55326727

Name	HuVeMOp_20240629201600757918_ORdGradInc_k_25-Pueyo_APDR-conf_608_1
Workunit	26271393
Created	29 Jun 2024, 18:17:46 UTC
Sent	29 Jun 2024, 19:53:15 UTC
Report deadline	3 Jul 2024, 5:29:15 UTC
Received	30 Jun 2024, 6:25:15 UTC
Server state	Over
Outcome	Success
Client state	Done
Exit status	0 (0x00000000)
Computer ID	216864
Run time	1 hours 28 min 47 sec
CPU time	54 min 19 sec
Validate state	Valid
Credit	64.05
Device peak FLOPS	5.42 GFLOPS
Application version	Human ventricular cell models optimization v0.02 arm64-apple-darwin
Peak working set size	2.98 MB
Peak swap size	391.90 GB
Peak disk usage	0.19 MB
Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-Pueyo_APDR-conf_608.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-Pueyo_APDR-conf_608_1_r1302557778_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-Pueyo_APDR-conf_608_1_r1302557778_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 98.242098
     * GNaL_b in INaL: 0.006399
     * Gto_b in Ito: 0.084435
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031191
     * GKs_b in IKs: 0.001762
     * GK1_b in IK1: 0.166013
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 73.896455
     * GKb_b in IKb: 0.003664
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019549
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14670483, states[0] = -94.559579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42443775, states[0] = -94.983762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75457289, states[0] = -94.964490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110082974, states[0] = -2.369319, states[40]= 0.003871
Saving checkpoint... 
Iteration: 136484177, states[0] = -94.958618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153314287, states[0] = -94.898071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188240005, states[0] = -94.818534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220897639, states[0] = -94.937784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250416647, states[0] = -94.943259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280049271, states[0] = 13.057340, states[40]= 0.004939
Saving checkpoint... 
Iteration: 296028213, states[0] = 19.995334, states[40]= 0.006165
Saving checkpoint... 
Iteration: 311286115, states[0] = -94.873629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346133809, states[0] = -47.099184, states[40]= 0.000048
Saving checkpoint... 
Iteration: 377386274, states[0] = -94.933685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402348934, states[0] = -94.917695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416098065, states[0] = -13.824581, states[40]= 0.001628
Saving checkpoint... 
Iteration: 441902423, states[0] = -94.938983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474541394, states[0] = 15.882377, states[40]= 0.005099
Saving checkpoint... 
Iteration: 504547762, states[0] = 13.611748, states[40]= 0.004957
Saving checkpoint... 
Iteration: 525611295, states[0] = -25.778033, states[40]= 0.000714
Saving checkpoint... 
Iteration: 543101498, states[0] = -16.908892, states[40]= 0.001237
Saving checkpoint... 
Iteration: 575052031, states[0] = 12.030274, states[40]= 0.004912
Saving checkpoint... 
Iteration: 606225925, states[0] = -94.795170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637998789, states[0] = -94.958322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660899023, states[0] = -94.937774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677363608, states[0] = -94.924465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708542026, states[0] = 15.662870, states[40]= 0.005079
Saving checkpoint... 
Iteration: 741866126, states[0] = -94.925520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775859001, states[0] = -94.922316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797905338, states[0] = -94.939620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815336725, states[0] = -94.910822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845564232, states[0] = 7.186778, states[40]= 0.004793
Saving checkpoint... 
Iteration: 881095528, states[0] = -11.599774, states[40]= 0.002005
Saving checkpoint... 
Iteration: 911331499, states[0] = -94.907688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942609765, states[0] = -24.393759, states[40]= 0.000776
Saving checkpoint... 
Iteration: 957521227, states[0] = 21.608577, states[40]= 0.008452
Saving checkpoint... 
Iteration: 976273731, states[0] = -94.860684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005573007, states[0] = 3.217714, states[40]= 0.004563
Saving checkpoint... 
Iteration: 1039092513, states[0] = -9.066142, states[40]= 0.002509
Saving checkpoint... 
Iteration: 1074104702, states[0] = -19.812377, states[40]= 0.001000
Saving checkpoint... 
Iteration: 1106072438, states[0] = 3.493137, states[40]= 0.004585
Saving checkpoint... 
Iteration: 1134762063, states[0] = -94.847292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169990057, states[0] = -94.956828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200647095, states[0] = -61.483859, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1222865824, states[0] = -94.925059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244960442, states[0] = -94.952167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263080387, states[0] = -0.677283, states[40]= 0.004132
Saving checkpoint... 
Iteration: 1279168381, states[0] = -91.725272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298851780, states[0] = -94.918505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309341886, states[0] = -94.913362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333978265, states[0] = -94.955033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354624114, states[0] = -37.551011, states[40]= 0.000199
Saving checkpoint... 
Iteration: 1375832381, states[0] = -94.907897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402466532, states[0] = -94.953114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430796346, states[0] = -94.882038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448520625, states[0] = 21.722520, states[40]= 0.008852
Saving checkpoint... 
Iteration: 1471994233, states[0] = -94.957172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500380403, states[0] = -8.948299, states[40]= 0.002754
Saving checkpoint... 
Iteration: 1525312117, states[0] = -44.841410, states[40]= 0.000069
Saving checkpoint... 
Iteration: 1556024767, states[0] = -95.140875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1575214293, states[0] = -95.129523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1589769804, states[0] = -3.245940, states[40]= 0.004208
Saving checkpoint... 
Iteration: 1609338322, states[0] = -83.596791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1635968962, states[0] = -2.697350, states[40]= 0.004321
Saving checkpoint... 
Iteration: 1660601367, states[0] = -34.959943, states[40]= 0.000279
Saving checkpoint... 
Iteration: 1684581729, states[0] = -14.396116, states[40]= 0.001751
Saving checkpoint... 
Iteration: 1697454135, states[0] = 6.552084, states[40]= 0.005469
Saving checkpoint... 
Iteration: 1722035708, states[0] = 15.555443, states[40]= 0.006308
Saving checkpoint... 
Iteration: 1751637752, states[0] = -95.170603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1777394354, states[0] = -95.097793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799786572, states[0] = -19.472402, states[40]= 0.001108
Saving checkpoint... 
Iteration: 1817719259, states[0] = -94.819473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850349154, states[0] = -94.931549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1876511151, states[0] = 23.130749, states[40]= 0.039532
Saving checkpoint... 
Iteration: 1906389517, states[0] = -94.936411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1938274936, states[0] = -94.862286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1964864387, states[0] = -94.924323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1994462314, states[0] = -94.952110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024136002, states[0] = -49.379655, states[40]= 0.000033
Saving checkpoint... 
Iteration: 2053025871, states[0] = 20.592740, states[40]= 0.006634
Saving checkpoint... 
Iteration: 2077163179, states[0] = -85.098030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098957027, states[0] = -94.950907, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.833289
 - CaMKt in component CaMK (millimolar): 0.007224
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.525774
 - nass in component intracellular_ions (millimolar): 6.525834
 - ki in component intracellular_ions (millimolar): 145.448705
 - kss in component intracellular_ions (millimolar): 145.448687
 - cansr in component intracellular_ions (millimolar): 1.324230
 - cajsr in component intracellular_ions (millimolar): 1.285493
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003644
 - hf in component INa (dimensionless): 0.878806
 - hs in component INa (dimensionless): 0.878801
 - j in component INa (dimensionless): 0.878770
 - hsp in component INa (dimensionless): 0.723581
 - jp in component INa (dimensionless): 0.878750
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.706733
 - hLp in component INaL (dimensionless): 0.445970
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.614936
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.688420
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930729
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999870
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001649
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.338102
 - xs1 in component IKs (dimensionless): 0.251112
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997355
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:21:32 (83370): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-Pueyo_APDR-conf_608.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-Pueyo_APDR-conf_608_1_r1302557778_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-Pueyo_APDR-conf_608_1_r1302557778_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 98.242098
     * GNaL_b in INaL: 0.006399
     * Gto_b in Ito: 0.084435
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031191
     * GKs_b in IKs: 0.001762
     * GK1_b in IK1: 0.166013
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 73.896455
     * GKb_b in IKb: 0.003664
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019549
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 2098957027
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.950907 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading resultsTime...
Loading resultsAPD90...
Loading resultsAPD75...
Loading resultsAPD50...
Loading resultsAPD25...
Loading resultsAPD10...
Loading resultsTriangulation...
Loading resultsMaxV...
Loading resultsMinV...
Loading resultsMaxDiffV...
Loading resultsMinDiffV...
Copy resultsTime...
Copy resultsAPD90...
Copy resultsAPD75...
Copy resultsAPD50...
Copy resultsAPD25...
Copy resultsAPD10...
Copy resultsTriangulation...
Copy resultsMaxV...
Copy resultsMinV...
Copy resultsMaxDiffV...
Copy resultsMinDiffV...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.833289
 - CaMKt in component CaMK (millimolar): 0.007224
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.525774
 - nass in component intracellular_ions (millimolar): 6.525834
 - ki in component intracellular_ions (millimolar): 145.448705
 - kss in component intracellular_ions (millimolar): 145.448687
 - cansr in component intracellular_ions (millimolar): 1.324230
 - cajsr in component intracellular_ions (millimolar): 1.285493
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003644
 - hf in component INa (dimensionless): 0.878806
 - hs in component INa (dimensionless): 0.878801
 - j in component INa (dimensionless): 0.878770
 - hsp in component INa (dimensionless): 0.723581
 - jp in component INa (dimensionless): 0.878750
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.706733
 - hLp in component INaL (dimensionless): 0.445970
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.614936
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.688420
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930729
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999870
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001649
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.338102
 - xs1 in component IKs (dimensionless): 0.251112
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997355
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:25:04 (41442): called boinc_finish(0)

</stderr_txt>
]]>