𝕏

Task 55325502

Name HuVeMOp_20240629201600757918_ORdGradInc_k_25-Pueyo_APDR-conf_401_1
Workunit 26270781
Created 29 Jun 2024, 18:16:38 UTC
Sent 29 Jun 2024, 19:42:03 UTC
Report deadline 3 Jul 2024, 5:18:03 UTC
Received 30 Jun 2024, 13:04:46 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241688
Run time 2 hours 6 min
CPU time 2 hours 2 min 56 sec
Validate state Valid
Credit 64.66
Device peak FLOPS 5.56 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.95 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-Pueyo_APDR-conf_401.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-Pueyo_APDR-conf_401_1_r2010166884_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-Pueyo_APDR-conf_401_1_r2010166884_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.010361
     * GNaL_b in INaL: 0.005042
     * Gto_b in Ito: 0.083377
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.034077
     * GKs_b in IKs: 0.002065
     * GK1_b in IK1: 0.179414
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 72.973359
     * GKb_b in IKb: 0.003700
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.043679
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17997062, states[0] = -95.150942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22019067, states[0] = 20.348287, states[40]= 0.010661
Saving checkpoint... 
Iteration: 40222668, states[0] = -94.982811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58324020, states[0] = -95.058524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76026507, states[0] = 18.888588, states[40]= 0.006804
Saving checkpoint... 
Iteration: 93263881, states[0] = -95.004735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111213506, states[0] = -94.940257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129028079, states[0] = 18.515655, states[40]= 0.006488
Saving checkpoint... 
Iteration: 146956128, states[0] = -95.080277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164821321, states[0] = -95.040018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182532720, states[0] = 17.012134, states[40]= 0.005838
Saving checkpoint... 
Iteration: 200297072, states[0] = -95.025142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217981083, states[0] = -95.082434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235516695, states[0] = 21.415097, states[40]= 0.014352
Saving checkpoint... 
Iteration: 253226437, states[0] = -94.955633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270726525, states[0] = -94.955723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288311006, states[0] = -95.033552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306307312, states[0] = -95.031346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323848632, states[0] = -95.051805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341453512, states[0] = -95.078572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358914923, states[0] = -95.071582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376576114, states[0] = -3.219442, states[40]= 0.003776
Saving checkpoint... 
Iteration: 394091610, states[0] = -17.061692, states[40]= 0.001219
Saving checkpoint... 
Iteration: 411824466, states[0] = -95.040786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429409790, states[0] = -95.070405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447373624, states[0] = -95.060672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465285252, states[0] = -95.016345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483085452, states[0] = -10.961724, states[40]= 0.002173
Saving checkpoint... 
Iteration: 500948669, states[0] = -95.077727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518889354, states[0] = -95.065264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536675665, states[0] = -94.866374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554195031, states[0] = -94.904879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572048127, states[0] = 11.072736, states[40]= 0.005034
Saving checkpoint... 
Iteration: 589675337, states[0] = -94.865575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607195853, states[0] = -94.906352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624949563, states[0] = -95.077791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642671761, states[0] = -94.855925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660689796, states[0] = -94.895014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678107891, states[0] = -33.774213, states[40]= 0.000277
Saving checkpoint... 
Iteration: 695785147, states[0] = -95.016124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713486101, states[0] = -95.082556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731178320, states[0] = -94.872119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748672254, states[0] = -94.857385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766366608, states[0] = -95.058175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784201746, states[0] = -94.916757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801600481, states[0] = -26.144291, states[40]= 0.000602
Saving checkpoint... 
Iteration: 819309725, states[0] = -95.032460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837344272, states[0] = -95.049692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854984977, states[0] = -95.082344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872537273, states[0] = 15.374760, states[40]= 0.005459
Saving checkpoint... 
Iteration: 890565710, states[0] = 3.029777, states[40]= 0.004608
Saving checkpoint... 
Iteration: 908559707, states[0] = 5.991864, states[40]= 0.004806
Saving checkpoint... 
Iteration: 926266539, states[0] = -95.000527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943719756, states[0] = -94.945622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961440364, states[0] = -95.076088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979283810, states[0] = -95.014935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996935717, states[0] = -95.075260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014244490, states[0] = -94.977868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031659161, states[0] = -94.568286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049356963, states[0] = -95.054578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067080368, states[0] = -6.454781, states[40]= 0.003125
Saving checkpoint... 
Iteration: 1084785131, states[0] = -95.015874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102773508, states[0] = -95.006555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120505564, states[0] = 27.004258, states[40]= 0.134711
Saving checkpoint... 
Iteration: 1138346281, states[0] = -95.050343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155893475, states[0] = -95.065980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173743291, states[0] = -94.976387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191628366, states[0] = -56.471766, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1209475897, states[0] = -95.081070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227138239, states[0] = -69.466331, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1245106074, states[0] = -31.894888, states[40]= 0.000347
Saving checkpoint... 
Iteration: 1262600900, states[0] = -26.573779, states[40]= 0.000582
Saving checkpoint... 
Iteration: 1280235631, states[0] = -94.967065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297956637, states[0] = -95.078446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315424125, states[0] = -95.072894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333112886, states[0] = -39.004593, states[40]= 0.000137
Saving checkpoint... 
Iteration: 1350939185, states[0] = -95.075649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368716793, states[0] = -94.940926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386584250, states[0] = -9.838576, states[40]= 0.002400
Saving checkpoint... 
Iteration: 1404184053, states[0] = -94.883398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421951660, states[0] = -95.077627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439803713, states[0] = -95.028431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457705469, states[0] = -94.922724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475793654, states[0] = -95.021792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493778877, states[0] = -95.010753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511607237, states[0] = -95.211737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1529075614, states[0] = -95.297465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546920233, states[0] = -72.188553, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1564800355, states[0] = -51.539921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1582571088, states[0] = -10.659394, states[40]= 0.002511
Saving checkpoint... 
Iteration: 1600262827, states[0] = -2.773875, states[40]= 0.004315
Saving checkpoint... 
Iteration: 1617684498, states[0] = -26.448811, states[40]= 0.000600
Saving checkpoint... 
Iteration: 1635284244, states[0] = -95.327202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652873193, states[0] = -95.190422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1670360458, states[0] = -95.310589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1688244009, states[0] = -95.090919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1706001184, states[0] = -95.242391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723788053, states[0] = -95.330201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1741202490, states[0] = 41.494858, states[40]= 0.089170
Saving checkpoint... 
Iteration: 1758722667, states[0] = -78.427237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776229748, states[0] = -95.280949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1793886399, states[0] = -95.217050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1811726794, states[0] = -94.993885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829268518, states[0] = -95.026908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846980850, states[0] = -95.095977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1864826151, states[0] = -95.049329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882378150, states[0] = -95.066206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1899977789, states[0] = -95.083794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1917576251, states[0] = -3.388413, states[40]= 0.003746
Saving checkpoint... 
Iteration: 1935038657, states[0] = 14.834994, states[40]= 0.005375
Saving checkpoint... 
Iteration: 1952603731, states[0] = -29.523581, states[40]= 0.000447
Saving checkpoint... 
Iteration: 1970308844, states[0] = -95.031542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987966247, states[0] = -95.079523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005657747, states[0] = -94.400482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023209120, states[0] = -94.928458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2041056227, states[0] = 7.586263, states[40]= 0.004881
Saving checkpoint... 
Iteration: 2058697537, states[0] = -94.908484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2076193906, states[0] = -94.901827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093653309, states[0] = -92.940263, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.958974
 - CaMKt in component CaMK (millimolar): 0.006725
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.539554
 - nass in component intracellular_ions (millimolar): 6.539612
 - ki in component intracellular_ions (millimolar): 145.440705
 - kss in component intracellular_ions (millimolar): 145.440685
 - cansr in component intracellular_ions (millimolar): 1.300361
 - cajsr in component intracellular_ions (millimolar): 1.263314
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003598
 - hf in component INa (dimensionless): 0.880988
 - hs in component INa (dimensionless): 0.880985
 - j in component INa (dimensionless): 0.880961
 - hsp in component INa (dimensionless): 0.727699
 - jp in component INa (dimensionless): 0.880945
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.713761
 - hLp in component INaL (dimensionless): 0.460968
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.630908
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.707887
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940511
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999905
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001557
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.317864
 - xs1 in component IKs (dimensionless): 0.228837
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997322
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:02:42 (1245387): called boinc_finish(0)

</stderr_txt>
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