𝕏

Task 55324184

Name HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_545_3
Workunit 25948201
Created 29 Jun 2024, 15:18:02 UTC
Sent 29 Jun 2024, 19:31:09 UTC
Report deadline 3 Jul 2024, 5:07:09 UTC
Received 1 Jul 2024, 7:53:44 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224229
Run time 2 hours 17 min 52 sec
CPU time 2 hours 1 min 56 sec
Validate state Valid
Credit 61.52
Device peak FLOPS 5.85 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 3.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_545.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_545_3_r174749694_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_545_3_r174749694_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 116.127809
     * GNaL_b in INaL: 0.006248
     * Gto_b in Ito: 0.074771
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033469
     * GKs_b in IKs: 0.001912
     * GK1_b in IK1: 0.152820
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 66.851458
     * GKb_b in IKb: 0.003821
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.040958
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 20139613, states[0] = -72.472254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 40106112, states[0] = -31.087857, states[40]= 0.000395
Saving checkpoint... 
Iteration: 60098968, states[0] = -23.002836, states[40]= 0.000782
Saving checkpoint... 
Iteration: 76501339, states[0] = 51.167329, states[40]= 0.042305
Saving checkpoint... 
Iteration: 93456331, states[0] = -95.120506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109341458, states[0] = -95.082548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123012805, states[0] = 23.720181, states[40]= 0.030044
Saving checkpoint... 
Iteration: 137695341, states[0] = -94.913881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152460919, states[0] = -95.115506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167137205, states[0] = -63.790283, states[40]= 0.000003
Saving checkpoint... 
Iteration: 182292558, states[0] = -95.046910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199512871, states[0] = 23.720999, states[40]= 0.029674
Saving checkpoint... 
Iteration: 216548079, states[0] = 12.058105, states[40]= 0.005265
Saving checkpoint... 
Iteration: 233565105, states[0] = 4.438605, states[40]= 0.004824
Saving checkpoint... 
Iteration: 250504323, states[0] = 33.143768, states[40]= 0.136649
Saving checkpoint... 
Iteration: 267982252, states[0] = -95.117355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285751425, states[0] = -95.004563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304218758, states[0] = -94.956402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323408130, states[0] = -95.102875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343002989, states[0] = 39.909343, states[40]= 0.113591
Saving checkpoint... 
Iteration: 362357047, states[0] = -95.085219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383047742, states[0] = 12.201178, states[40]= 0.005275
Saving checkpoint... 
Iteration: 403424647, states[0] = -95.106944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423342451, states[0] = -95.078372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442492957, states[0] = -95.118584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462082251, states[0] = -6.143055, states[40]= 0.003231
Saving checkpoint... 
Iteration: 482004089, states[0] = 34.076205, states[40]= 0.135484
Saving checkpoint... 
Iteration: 502412378, states[0] = -95.103891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522102747, states[0] = -25.758578, states[40]= 0.000645
Saving checkpoint... 
Iteration: 541658400, states[0] = -92.820055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560568227, states[0] = 2.847544, states[40]= 0.004688
Saving checkpoint... 
Iteration: 578349135, states[0] = -95.081528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595425453, states[0] = -95.107027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612490339, states[0] = -95.118172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631553429, states[0] = 9.801259, states[40]= 0.005132
Saving checkpoint... 
Iteration: 649317525, states[0] = -95.064149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667195089, states[0] = -94.911019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685742327, states[0] = -94.992460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704429796, states[0] = -95.107945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722859731, states[0] = -95.086179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741318731, states[0] = -95.064865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757931480, states[0] = -95.108285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774799213, states[0] = -95.051285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791866379, states[0] = -95.088874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808131594, states[0] = -56.897655, states[40]= 0.000008
Saving checkpoint... 
Iteration: 825175272, states[0] = -94.854037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840445214, states[0] = -95.111035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855340744, states[0] = -95.077284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871010281, states[0] = 24.619053, states[40]= 0.050934
Saving checkpoint... 
Iteration: 889701590, states[0] = -94.924165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907439043, states[0] = -95.109789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925552065, states[0] = 10.386185, states[40]= 0.005163
Saving checkpoint... 
Iteration: 942011186, states[0] = 24.257570, states[40]= 0.041912
Saving checkpoint... 
Iteration: 958891313, states[0] = -95.097631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975645794, states[0] = -75.794147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993031145, states[0] = 18.587290, states[40]= 0.006475
Saving checkpoint... 
Iteration: 1008457679, states[0] = -95.113190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023044536, states[0] = 13.513692, states[40]= 0.005385
Saving checkpoint... 
Iteration: 1033501713, states[0] = 49.354473, states[40]= 0.060643
Saving checkpoint... 
Iteration: 1041482991, states[0] = -95.116997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054697023, states[0] = -94.914825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069195238, states[0] = -94.911118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085310599, states[0] = -95.059351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099082991, states[0] = -6.739599, states[40]= 0.003100
Saving checkpoint... 
Iteration: 1111308110, states[0] = -95.057617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124310845, states[0] = -95.059498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137424433, states[0] = -95.106508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151360150, states[0] = -95.086131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165117421, states[0] = -40.832370, states[40]= 0.000110
Saving checkpoint... 
Iteration: 1179083467, states[0] = -7.131081, states[40]= 0.003014
Saving checkpoint... 
Iteration: 1192816644, states[0] = -95.063299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207642814, states[0] = -71.256672, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1223393381, states[0] = -95.098137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239944265, states[0] = -95.110643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254710246, states[0] = -94.940642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267560689, states[0] = 6.559785, states[40]= 0.004964
Saving checkpoint... 
Iteration: 1281627669, states[0] = -52.304759, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1295511850, states[0] = 24.030715, states[40]= 0.036457
Saving checkpoint... 
Iteration: 1309125016, states[0] = -49.251205, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1321960156, states[0] = -95.113442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337467347, states[0] = -95.114587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350970107, states[0] = -95.115002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363673743, states[0] = -94.842188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373608781, states[0] = -31.861518, states[40]= 0.000364
Saving checkpoint... 
Iteration: 1384802948, states[0] = -95.053767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395271226, states[0] = -95.026233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406967735, states[0] = -95.114610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418468438, states[0] = -95.114713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430832992, states[0] = -95.072888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442594990, states[0] = -17.962240, states[40]= 0.001141
Saving checkpoint... 
Iteration: 1454382874, states[0] = -95.094606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465753826, states[0] = -95.006859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477627532, states[0] = -52.145921, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1490478623, states[0] = -95.116165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502311404, states[0] = -95.261761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513367655, states[0] = -95.187932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526327923, states[0] = -95.317504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539705410, states[0] = -47.232290, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1553224333, states[0] = -73.880363, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1567139379, states[0] = -95.358255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1580754730, states[0] = 4.223440, states[40]= 0.005443
Saving checkpoint... 
Iteration: 1598329754, states[0] = -95.352683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615584161, states[0] = -23.469914, states[40]= 0.000792
Saving checkpoint... 
Iteration: 1630154770, states[0] = -95.384232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1645772884, states[0] = -95.401395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1661002433, states[0] = -95.313616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1676362343, states[0] = -95.392645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1691760096, states[0] = 0.526765, states[40]= 0.004976
Saving checkpoint... 
Iteration: 1707262420, states[0] = -95.392903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1721024293, states[0] = -95.348989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1733470145, states[0] = -7.937629, states[40]= 0.003186
Saving checkpoint... 
Iteration: 1747504676, states[0] = 33.084098, states[40]= 0.115802
Saving checkpoint... 
Iteration: 1761600340, states[0] = -53.471073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774870187, states[0] = -7.981044, states[40]= 0.003176
Saving checkpoint... 
Iteration: 1788696141, states[0] = -37.429373, states[40]= 0.000182
Saving checkpoint... 
Iteration: 1802845073, states[0] = -95.146468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1816675522, states[0] = -94.908025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1830246817, states[0] = -95.031401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843393631, states[0] = -95.120776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856349020, states[0] = -95.096610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869875091, states[0] = -95.102342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883934100, states[0] = -95.115398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897815848, states[0] = -95.067240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1911717955, states[0] = -94.957447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1926154401, states[0] = -89.569528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940395941, states[0] = -95.099946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954994373, states[0] = -95.118875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1969827078, states[0] = -95.069856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1984605766, states[0] = -28.828680, states[40]= 0.000499
Saving checkpoint... 
Iteration: 1998902067, states[0] = -95.100538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013326426, states[0] = -95.069006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028422614, states[0] = -95.105691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2042069082, states[0] = 2.391757, states[40]= 0.004644
Saving checkpoint... 
Iteration: 2055895122, states[0] = -95.098243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070720402, states[0] = -94.958251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086119028, states[0] = -42.566487, states[40]= 0.000085
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.994389
 - CaMKt in component CaMK (millimolar): 0.006617
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.608431
 - nass in component intracellular_ions (millimolar): 6.608492
 - ki in component intracellular_ions (millimolar): 145.373898
 - kss in component intracellular_ions (millimolar): 145.373877
 - cansr in component intracellular_ions (millimolar): 1.295172
 - cajsr in component intracellular_ions (millimolar): 1.258072
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003585
 - hf in component INa (dimensionless): 0.881597
 - hs in component INa (dimensionless): 0.881593
 - j in component INa (dimensionless): 0.881565
 - hsp in component INa (dimensionless): 0.728846
 - jp in component INa (dimensionless): 0.881546
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.713644
 - hLp in component INaL (dimensionless): 0.458672
 - a in component Ito (dimensionless): 0.000620
 - iF in component Ito (dimensionless): 0.999872
 - iS in component Ito (dimensionless): 0.627395
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999872
 - iSp in component Ito (dimensionless): 0.703066
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936419
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999892
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001549
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.336686
 - xs1 in component IKs (dimensionless): 0.235468
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997313
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:53:20 (422585): called boinc_finish(0)

</stderr_txt>
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