𝕏

Task 55320455

Name HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_592_0
Workunit 26269343
Created 29 Jun 2024, 9:38:11 UTC
Sent 29 Jun 2024, 18:57:05 UTC
Report deadline 3 Jul 2024, 4:33:05 UTC
Received 30 Jun 2024, 7:20:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 235140
Run time 1 hours 53 min 55 sec
CPU time 1 hours 53 min 50 sec
Validate state Valid
Credit 59.69
Device peak FLOPS 6.51 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.81 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.16.6</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_592.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_592_0_r1959117172_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_592_0_r1959117172_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.937560
     * GNaL_b in INaL: 0.005321
     * Gto_b in Ito: 0.076677
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031924
     * GKs_b in IKs: 0.001798
     * GK1_b in IK1: 0.157852
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 66.973685
     * GKb_b in IKb: 0.003756
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025260
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 19141678, states[0] = -70.607821, states[40]= 0.000001
Saving checkpoint... 
Iteration: 38292671, states[0] = -95.002734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57478938, states[0] = -95.062379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76651169, states[0] = -80.353832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95825507, states[0] = -95.000275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115006658, states[0] = 26.664236, states[40]= 0.110608
Saving checkpoint... 
Iteration: 134197375, states[0] = -94.836479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153395466, states[0] = -95.026995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172572848, states[0] = 0.681828, states[40]= 0.004425
Saving checkpoint... 
Iteration: 191784636, states[0] = -94.963516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210964733, states[0] = -95.042347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230044733, states[0] = 13.448801, states[40]= 0.005266
Saving checkpoint... 
Iteration: 249075744, states[0] = -1.001166, states[40]= 0.004191
Saving checkpoint... 
Iteration: 268112185, states[0] = -33.454441, states[40]= 0.000314
Saving checkpoint... 
Iteration: 287292254, states[0] = -94.969891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306418998, states[0] = -95.032507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325352243, states[0] = -95.008757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344520409, states[0] = 21.572270, states[40]= 0.009814
Saving checkpoint... 
Iteration: 363483910, states[0] = -95.044984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382493548, states[0] = -95.046265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401481139, states[0] = -95.044565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420628573, states[0] = -50.351417, states[40]= 0.000026
Saving checkpoint... 
Iteration: 439783195, states[0] = -94.961626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458917654, states[0] = -95.032053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477622049, states[0] = -43.395784, states[40]= 0.000078
Saving checkpoint... 
Iteration: 496503953, states[0] = 33.415992, states[40]= 0.148477
Saving checkpoint... 
Iteration: 515442917, states[0] = -95.037873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534392340, states[0] = -95.024598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553315626, states[0] = -94.987615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572258285, states[0] = -94.934880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591444035, states[0] = -95.038056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610493382, states[0] = -95.046105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629574021, states[0] = 0.029000, states[40]= 0.004339
Saving checkpoint... 
Iteration: 648649192, states[0] = -75.837564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667723901, states[0] = -94.885010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686833221, states[0] = -94.998549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705906422, states[0] = -95.028830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724951326, states[0] = -95.039412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743983319, states[0] = -95.044669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763034930, states[0] = 17.153839, states[40]= 0.005806
Saving checkpoint... 
Iteration: 782056708, states[0] = 8.524503, states[40]= 0.005010
Saving checkpoint... 
Iteration: 801139670, states[0] = -62.860405, states[40]= 0.000003
Saving checkpoint... 
Iteration: 820243903, states[0] = -94.915958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839369710, states[0] = -95.016141, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_592.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_592_0_r1959117172_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_592_0_r1959117172_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.937560
     * GNaL_b in INaL: 0.005321
     * Gto_b in Ito: 0.076677
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031924
     * GKs_b in IKs: 0.001798
     * GK1_b in IK1: 0.157852
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 66.973685
     * GKb_b in IKb: 0.003756
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025260
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 839369710
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.016141 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 857181524, states[0] = -94.794437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875098218, states[0] = -19.829119, states[40]= 0.000988
Saving checkpoint... 
Iteration: 892949901, states[0] = -95.039037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910618969, states[0] = -40.224044, states[40]= 0.000125
Saving checkpoint... 
Iteration: 928703658, states[0] = -94.846997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947979786, states[0] = -95.044038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967303255, states[0] = -94.978402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986607622, states[0] = -28.980560, states[40]= 0.000511
Saving checkpoint... 
Iteration: 1005968285, states[0] = -95.042230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025316043, states[0] = -94.987614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044693317, states[0] = -94.825135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064097381, states[0] = -19.015257, states[40]= 0.001051
Saving checkpoint... 
Iteration: 1083491682, states[0] = -95.045600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102872989, states[0] = -95.017292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122246288, states[0] = -94.919081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141614086, states[0] = -35.327806, states[40]= 0.000247
Saving checkpoint... 
Iteration: 1160989280, states[0] = -95.045236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180372930, states[0] = -95.017222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199752130, states[0] = -94.926801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219126358, states[0] = -47.956972, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1238507648, states[0] = 25.603311, states[40]= 0.089941
Saving checkpoint... 
Iteration: 1257892682, states[0] = -95.024274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277278709, states[0] = -94.956801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296672988, states[0] = -94.711876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316044838, states[0] = 13.409636, states[40]= 0.005263
Saving checkpoint... 
Iteration: 1335436215, states[0] = -95.035956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354813644, states[0] = -94.985767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374196890, states[0] = -94.832658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393582236, states[0] = -5.404228, states[40]= 0.003373
Saving checkpoint... 
Iteration: 1412959437, states[0] = -95.040485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432356525, states[0] = -95.010088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451716612, states[0] = -94.871659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471081124, states[0] = -4.581355, states[40]= 0.003545
Saving checkpoint... 
Iteration: 1490486090, states[0] = -95.044605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509855997, states[0] = -95.246901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1529178192, states[0] = -13.980046, states[40]= 0.001841
Saving checkpoint... 
Iteration: 1548505838, states[0] = -95.210684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567838199, states[0] = 13.556979, states[40]= 0.006401
Saving checkpoint... 
Iteration: 1587135384, states[0] = -89.111421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606451362, states[0] = -95.289865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1625745840, states[0] = 9.508844, states[40]= 0.005907
Saving checkpoint... 
Iteration: 1645029349, states[0] = -79.329451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1664309666, states[0] = -95.234283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1683615306, states[0] = 22.827365, states[40]= 0.019723
Saving checkpoint... 
Iteration: 1702918974, states[0] = -63.302346, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1722211065, states[0] = -95.237025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1741466020, states[0] = -95.307347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1760740877, states[0] = 12.080260, states[40]= 0.006202
Saving checkpoint... 
Iteration: 1780044683, states[0] = -94.691368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799327335, states[0] = -95.262437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818575622, states[0] = -2.344404, states[40]= 0.004027
Saving checkpoint... 
Iteration: 1837752566, states[0] = -94.951808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856934043, states[0] = -95.049300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1876138542, states[0] = -62.204753, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1895406078, states[0] = -95.032685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914655229, states[0] = -86.171450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933911712, states[0] = -95.031104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953119824, states[0] = -41.157513, states[40]= 0.000109
Saving checkpoint... 
Iteration: 1972296216, states[0] = -94.972666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991507608, states[0] = 25.637655, states[40]= 0.090732
Saving checkpoint... 
Iteration: 2010695952, states[0] = -94.830394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029865717, states[0] = -95.013823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049067435, states[0] = 3.570682, states[40]= 0.004721
Saving checkpoint... 
Iteration: 2068296530, states[0] = -94.972365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2087500838, states[0] = 46.040379, states[40]= 0.015813
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.921868
 - CaMKt in component CaMK (millimolar): 0.006886
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.626737
 - nass in component intracellular_ions (millimolar): 6.626797
 - ki in component intracellular_ions (millimolar): 145.351237
 - kss in component intracellular_ions (millimolar): 145.351217
 - cansr in component intracellular_ions (millimolar): 1.311783
 - cajsr in component intracellular_ions (millimolar): 1.274244
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003611
 - hf in component INa (dimensionless): 0.880348
 - hs in component INa (dimensionless): 0.880343
 - j in component INa (dimensionless): 0.880313
 - hsp in component INa (dimensionless): 0.726483
 - jp in component INa (dimensionless): 0.880293
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711012
 - hLp in component INaL (dimensionless): 0.454303
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.624163
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.699386
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936059
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001609
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.333649
 - xs1 in component IKs (dimensionless): 0.237590
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997332
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:17:07 (4152): called boinc_finish(0)

</stderr_txt>
]]>