𝕏

Task 55317916

Name HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_83_0
Workunit 26268074
Created 29 Jun 2024, 9:36:57 UTC
Sent 29 Jun 2024, 18:41:21 UTC
Report deadline 3 Jul 2024, 4:17:21 UTC
Received 1 Jul 2024, 12:59:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 190678
Run time 2 hours 55 min 42 sec
CPU time 2 hours 52 min 59 sec
Validate state Valid
Credit 69.07
Device peak FLOPS 3.57 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 5.92 MB
Peak swap size 1.38 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.6.33</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_83.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_83_0_r876371714_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_83_0_r876371714_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 90.524296
     * GNaL_b in INaL: 0.006621
     * Gto_b in Ito: 0.084830
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033496
     * GKs_b in IKs: 0.001980
     * GK1_b in IK1: 0.152713
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 75.279395
     * GKb_b in IKb: 0.003910
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.048406
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 5178547, states[0] = -94.987366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17264677, states[0] = -95.047833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28782669, states[0] = -95.026683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40951556, states[0] = -95.077557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53110416, states[0] = -30.451273, states[40]= 0.000428
Saving checkpoint... 
Iteration: 65272241, states[0] = -94.964568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77388698, states[0] = -95.028457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89557496, states[0] = 8.743274, states[40]= 0.004796
Saving checkpoint... 
Iteration: 101703002, states[0] = -94.845358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113881852, states[0] = -95.015529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126030257, states[0] = 18.773075, states[40]= 0.005895
Saving checkpoint... 
Iteration: 138217216, states[0] = -94.867220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150284674, states[0] = -94.955226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162462812, states[0] = -95.031296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174640436, states[0] = -60.350170, states[40]= 0.000005
Saving checkpoint... 
Iteration: 186793838, states[0] = -94.962039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198992859, states[0] = -95.034715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211174282, states[0] = -94.639869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223285586, states[0] = -94.954454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235464355, states[0] = -95.030429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247651297, states[0] = -74.458860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259839334, states[0] = -94.991883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271990738, states[0] = -95.034051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284183423, states[0] = -94.787837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296367379, states[0] = -95.004788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308550980, states[0] = 11.514427, states[40]= 0.004866
Saving checkpoint... 
Iteration: 320695274, states[0] = -94.821643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332845161, states[0] = -94.994774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345018081, states[0] = 21.661826, states[40]= 0.011511
Saving checkpoint... 
Iteration: 356981700, states[0] = -95.032784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369117750, states[0] = -35.883350, states[40]= 0.000222
Saving checkpoint... 
Iteration: 381268925, states[0] = -94.937684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393347357, states[0] = -94.995815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405520771, states[0] = 21.178067, states[40]= 0.008865
Saving checkpoint... 
Iteration: 417684775, states[0] = -94.793638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429865260, states[0] = -95.003822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442067442, states[0] = 4.593649, states[40]= 0.004609
Saving checkpoint... 
Iteration: 454239146, states[0] = -94.900127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466430436, states[0] = -95.023738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478584016, states[0] = -4.873130, states[40]= 0.003362
Saving checkpoint... 
Iteration: 490724459, states[0] = -94.877043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502910703, states[0] = -95.018919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515023734, states[0] = 20.543447, states[40]= 0.007349
Saving checkpoint... 
Iteration: 527143392, states[0] = -63.809985, states[40]= 0.000002
Saving checkpoint... 
Iteration: 539316005, states[0] = -94.977777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551476111, states[0] = -95.031880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563664505, states[0] = -92.488036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575820621, states[0] = -94.980759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588000130, states[0] = -79.050645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600171648, states[0] = -94.470577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612357755, states[0] = -95.000510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624488866, states[0] = -95.033553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636633904, states[0] = -52.868237, states[40]= 0.000017
Saving checkpoint... 
Iteration: 648788449, states[0] = -94.956551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660980976, states[0] = -95.032493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673158031, states[0] = -85.311195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685353801, states[0] = -94.998684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697534145, states[0] = 17.601392, states[40]= 0.005487
Saving checkpoint... 
Iteration: 709694183, states[0] = -94.819023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721761496, states[0] = -94.929158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733628616, states[0] = -47.055068, states[40]= 0.000043
Saving checkpoint... 
Iteration: 745758333, states[0] = -94.925406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757919372, states[0] = -95.020978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770112437, states[0] = -30.725280, states[40]= 0.000417
Saving checkpoint... 
Iteration: 782283225, states[0] = -94.951743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794469388, states[0] = -95.030735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806654016, states[0] = -78.737485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818832881, states[0] = -94.987949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831029207, states[0] = 19.117024, states[40]= 0.006047
Saving checkpoint... 
Iteration: 843218316, states[0] = -94.866196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855406530, states[0] = -95.017565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867473566, states[0] = -95.031315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879617960, states[0] = -36.089368, states[40]= 0.000215
Saving checkpoint... 
Iteration: 891793775, states[0] = -94.960963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903890539, states[0] = -95.012749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916043277, states[0] = 14.420791, states[40]= 0.005011
Saving checkpoint... 
Iteration: 928238174, states[0] = -94.898404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940417746, states[0] = -95.020462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952556306, states[0] = 9.408184, states[40]= 0.004808
Saving checkpoint... 
Iteration: 964758768, states[0] = -94.925790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976941006, states[0] = -95.025644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989085704, states[0] = -6.124865, states[40]= 0.003106
Saving checkpoint... 
Iteration: 1001259568, states[0] = -94.926720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013431695, states[0] = -95.023674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025609740, states[0] = -28.136859, states[40]= 0.000537
Saving checkpoint... 
Iteration: 1037780299, states[0] = -94.948824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049945143, states[0] = -95.026410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062138135, states[0] = -57.638169, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1074283090, states[0] = -94.951435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086457678, states[0] = -95.028661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098641229, states[0] = -61.221441, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1110764781, states[0] = -94.932669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122957512, states[0] = -95.028610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135128966, states[0] = -47.433469, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1147293159, states[0] = -94.960288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159463747, states[0] = -95.029623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171640513, states[0] = -60.381848, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1183826313, states[0] = -94.983900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196004342, states[0] = 29.532791, states[40]= 0.151754
Saving checkpoint... 
Iteration: 1208184196, states[0] = -94.790751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220370716, states[0] = -95.005513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232485310, states[0] = -95.032717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244663109, states[0] = -91.506916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256843337, states[0] = -94.993273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269014521, states[0] = 22.183929, states[40]= 0.019543
Saving checkpoint... 
Iteration: 1281204882, states[0] = -94.840710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293407588, states[0] = -95.017585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305618587, states[0] = -36.706996, states[40]= 0.000198
Saving checkpoint... 
Iteration: 1317796537, states[0] = -94.962968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329975769, states[0] = -95.031347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342166706, states[0] = -93.513509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354257702, states[0] = -94.924266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366428041, states[0] = -95.022642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378606613, states[0] = -25.149288, states[40]= 0.000676
Saving checkpoint... 
Iteration: 1390788690, states[0] = -94.956300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402930658, states[0] = -95.023204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415109193, states[0] = -27.613222, states[40]= 0.000562
Saving checkpoint... 
Iteration: 1427296128, states[0] = -94.962568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439426922, states[0] = -95.022343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451155734, states[0] = -81.573443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463258930, states[0] = -94.925672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475417046, states[0] = -95.019954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487593295, states[0] = -12.541949, states[40]= 0.001818
Saving checkpoint... 
Iteration: 1499750297, states[0] = -94.914874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511908427, states[0] = -95.187777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1524062067, states[0] = 1.192975, states[40]= 0.004852
Saving checkpoint... 
Iteration: 1536191771, states[0] = -95.182869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548239541, states[0] = -95.269243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560374889, states[0] = -10.069193, states[40]= 0.002587
Saving checkpoint... 
Iteration: 1572511851, states[0] = -95.239134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1582418364, states[0] = -95.251946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1594340498, states[0] = -92.509911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606374280, states[0] = -95.166836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1618397887, states[0] = -95.220093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630506236, states[0] = 26.415423, states[40]= 0.109219
Saving checkpoint... 
Iteration: 1642612600, states[0] = -53.026896, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1654673550, states[0] = -95.167049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666591759, states[0] = -28.881659, states[40]= 0.000495
Saving checkpoint... 
Iteration: 1678662970, states[0] = -95.137052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1690801179, states[0] = 46.552904, states[40]= 0.032690
Saving checkpoint... 
Iteration: 1702873165, states[0] = -8.789234, states[40]= 0.002887
Saving checkpoint... 
Iteration: 1714641061, states[0] = -92.995101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1726501414, states[0] = 46.527090, states[40]= 0.045736
Saving checkpoint... 
Iteration: 1738563840, states[0] = -0.918729, states[40]= 0.004577
Saving checkpoint... 
Iteration: 1750660285, states[0] = -95.126346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762736306, states[0] = -95.282926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774851725, states[0] = 6.588989, states[40]= 0.005404
Saving checkpoint... 
Iteration: 1787009631, states[0] = -95.243254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799113871, states[0] = 22.410414, states[40]= 0.023590
Saving checkpoint... 
Iteration: 1811220392, states[0] = -94.921985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1823368446, states[0] = -95.044166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835433674, states[0] = -95.051570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847572806, states[0] = 1.501895, states[40]= 0.004368
Saving checkpoint... 
Iteration: 1859604814, states[0] = -24.096131, states[40]= 0.000725
Saving checkpoint... 
Iteration: 1871743853, states[0] = -94.915367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883769140, states[0] = -94.943466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895932680, states[0] = -95.027766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1908080334, states[0] = -2.462870, states[40]= 0.003811
Saving checkpoint... 
Iteration: 1920214014, states[0] = -94.859875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932265926, states[0] = -94.934896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944408659, states[0] = -95.018457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956510783, states[0] = 22.760470, states[40]= 0.042469
Saving checkpoint... 
Iteration: 1968663904, states[0] = -92.121977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980811262, states[0] = -94.973937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1992931029, states[0] = -95.023105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004996587, states[0] = -95.033748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017138407, states[0] = -57.956093, states[40]= 0.000007
Saving checkpoint... 
Iteration: 2029281718, states[0] = -94.949579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2041416614, states[0] = -95.019493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2053527106, states[0] = 19.700109, states[40]= 0.006418
Saving checkpoint... 
Iteration: 2065597652, states[0] = -16.613223, states[40]= 0.001241
Saving checkpoint... 
Iteration: 2077693465, states[0] = -94.816544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2089846561, states[0] = -94.994323, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.909800
 - CaMKt in component CaMK (millimolar): 0.006812
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.425258
 - nass in component intracellular_ions (millimolar): 6.425317
 - ki in component intracellular_ions (millimolar): 145.555567
 - kss in component intracellular_ions (millimolar): 145.555547
 - cansr in component intracellular_ions (millimolar): 1.297305
 - cajsr in component intracellular_ions (millimolar): 1.259374
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003616
 - hf in component INa (dimensionless): 0.880139
 - hs in component INa (dimensionless): 0.880134
 - j in component INa (dimensionless): 0.880106
 - hsp in component INa (dimensionless): 0.726091
 - jp in component INa (dimensionless): 0.880087
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710002
 - hLp in component INaL (dimensionless): 0.451804
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620852
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695591
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934667
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001543
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.324314
 - xs1 in component IKs (dimensionless): 0.243159
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:31:26 (4180): called boinc_finish(0)

</stderr_txt>
]]>


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