𝕏

Task 55317790

Name HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_782_0
Workunit 26268011
Created 29 Jun 2024, 9:36:52 UTC
Sent 29 Jun 2024, 18:37:41 UTC
Report deadline 3 Jul 2024, 4:13:41 UTC
Received 2 Jul 2024, 23:02:51 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 219798
Run time 2 hours 59 min 42 sec
CPU time 2 hours 49 min 3 sec
Validate state Valid
Credit 62.57
Device peak FLOPS 2.33 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.75 MB
Peak swap size 6.39 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_782.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_782_0_r1158155115_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_782_0_r1158155115_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.234147
     * GNaL_b in INaL: 0.005140
     * Gto_b in Ito: 0.092741
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032242
     * GKs_b in IKs: 0.001840
     * GK1_b in IK1: 0.163841
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 67.067253
     * GKb_b in IKb: 0.003791
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050296
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11709717, states[0] = -94.993852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22275358, states[0] = -95.051823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33256062, states[0] = -95.016204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44836103, states[0] = -95.068656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57943526, states[0] = -95.095617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71274870, states[0] = -95.012441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84685938, states[0] = -94.871845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97962315, states[0] = -95.088006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110902421, states[0] = -95.073910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124398315, states[0] = -95.071670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137715225, states[0] = -94.924481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151060569, states[0] = 6.656998, states[40]= 0.004713
Saving checkpoint... 
Iteration: 163903820, states[0] = -95.071623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176030848, states[0] = 17.657310, states[40]= 0.005726
Saving checkpoint... 
Iteration: 189464764, states[0] = -95.083789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202904525, states[0] = -95.071292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216421654, states[0] = -95.075459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229890842, states[0] = -95.067221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243426025, states[0] = -95.076333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256633889, states[0] = -55.348031, states[40]= 0.000011
Saving checkpoint... 
Iteration: 270159754, states[0] = -91.317911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283725352, states[0] = -94.939713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297291312, states[0] = -95.015997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310825641, states[0] = -95.039416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323912602, states[0] = -95.073068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337442371, states[0] = -95.079531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350325446, states[0] = -95.039270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362538512, states[0] = 15.181945, states[40]= 0.005140
Saving checkpoint... 
Iteration: 376086815, states[0] = -8.757992, states[40]= 0.002572
Saving checkpoint... 
Iteration: 389562877, states[0] = 5.669339, states[40]= 0.004670
Saving checkpoint... 
Iteration: 403117847, states[0] = -38.372758, states[40]= 0.000159
Saving checkpoint... 
Iteration: 416703978, states[0] = -94.902000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430224391, states[0] = -94.938053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443704446, states[0] = -94.902881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457050028, states[0] = 10.953463, states[40]= 0.004840
Saving checkpoint... 
Iteration: 470589508, states[0] = -11.106971, states[40]= 0.002097
Saving checkpoint... 
Iteration: 484153057, states[0] = -81.504735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497491463, states[0] = -95.086836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511002685, states[0] = 38.219338, states[40]= 0.128077
Saving checkpoint... 
Iteration: 524512940, states[0] = 21.354635, states[40]= 0.027022
Saving checkpoint... 
Iteration: 537378523, states[0] = -95.062908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549618738, states[0] = -39.264989, states[40]= 0.000140
Saving checkpoint... 
Iteration: 562700546, states[0] = -94.895199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576211283, states[0] = -94.915552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589747103, states[0] = -94.970549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603320317, states[0] = -95.036077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616873422, states[0] = -95.061060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630402315, states[0] = -95.070162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643943498, states[0] = -95.079529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657476195, states[0] = -95.084776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669655825, states[0] = -86.251394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682020924, states[0] = 20.134392, states[40]= 0.008595
Saving checkpoint... 
Iteration: 694315515, states[0] = -95.033048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706420878, states[0] = -95.074785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717486509, states[0] = -95.086084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728924987, states[0] = -95.075699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741112900, states[0] = -33.494755, states[40]= 0.000305
Saving checkpoint... 
Iteration: 752451599, states[0] = -95.080911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764682685, states[0] = -94.855100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776935094, states[0] = -95.077806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788818834, states[0] = -95.035049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800549082, states[0] = 11.316318, states[40]= 0.004852
Saving checkpoint... 
Iteration: 812420889, states[0] = -95.074715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824493581, states[0] = -95.086863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836744861, states[0] = -94.967487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848556968, states[0] = 8.195111, states[40]= 0.004763
Saving checkpoint... 
Iteration: 860080630, states[0] = -3.994290, states[40]= 0.003556
Saving checkpoint... 
Iteration: 871328004, states[0] = -95.040360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882183166, states[0] = -94.856458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893232761, states[0] = -94.950631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905039953, states[0] = 14.678080, states[40]= 0.005077
Saving checkpoint... 
Iteration: 917096830, states[0] = -17.980262, states[40]= 0.001113
Saving checkpoint... 
Iteration: 928605370, states[0] = -26.199830, states[40]= 0.000629
Saving checkpoint... 
Iteration: 940475608, states[0] = -95.084503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952663697, states[0] = -93.680200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965237354, states[0] = -94.957212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977542165, states[0] = 13.887384, states[40]= 0.004998
Saving checkpoint... 
Iteration: 989876223, states[0] = -95.061802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002123337, states[0] = -43.965875, states[40]= 0.000069
Saving checkpoint... 
Iteration: 1014348540, states[0] = -95.050664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026548030, states[0] = 11.716527, states[40]= 0.004868
Saving checkpoint... 
Iteration: 1038749764, states[0] = -94.973589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049357346, states[0] = -95.054503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061125151, states[0] = -45.867466, states[40]= 0.000052
Saving checkpoint... 
Iteration: 1073252724, states[0] = -94.977183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085407162, states[0] = -95.071152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098131250, states[0] = -52.431355, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1110790056, states[0] = -95.014405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123336630, states[0] = -95.044813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135920627, states[0] = -95.074434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148432606, states[0] = -95.077045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160929721, states[0] = -95.076433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173225436, states[0] = -94.939213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185541172, states[0] = 14.244676, states[40]= 0.005031
Saving checkpoint... 
Iteration: 1198142174, states[0] = -65.028465, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1210499637, states[0] = -95.087285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221629244, states[0] = -50.246688, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1232988355, states[0] = -95.085962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245334467, states[0] = -95.043606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257659846, states[0] = -91.397440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269954665, states[0] = -95.081083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282342528, states[0] = -95.047649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294492130, states[0] = -95.086373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306987846, states[0] = -95.085849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319050118, states[0] = 10.919005, states[40]= 0.004839
Saving checkpoint... 
Iteration: 1332458419, states[0] = -95.081660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346008929, states[0] = 22.272938, states[40]= 0.068591
Saving checkpoint... 
Iteration: 1359563426, states[0] = 5.424054, states[40]= 0.004658
Saving checkpoint... 
Iteration: 1372823145, states[0] = -95.037235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385609637, states[0] = -30.321754, states[40]= 0.000437
Saving checkpoint... 
Iteration: 1397369877, states[0] = -95.059229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410854562, states[0] = -95.053071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424439064, states[0] = -95.078153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437938086, states[0] = -95.077953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451457967, states[0] = -95.081506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464796723, states[0] = -95.019436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478328520, states[0] = -95.040234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491923228, states[0] = -95.074786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505454402, states[0] = 5.546792, states[40]= 0.005211
Saving checkpoint... 
Iteration: 1518750615, states[0] = -95.014170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1532187038, states[0] = -24.253399, states[40]= 0.000736
Saving checkpoint... 
Iteration: 1545680452, states[0] = -17.448202, states[40]= 0.001297
Saving checkpoint... 
Iteration: 1559149640, states[0] = 7.175507, states[40]= 0.005453
Saving checkpoint... 
Iteration: 1571871987, states[0] = -95.191457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1583942478, states[0] = -95.314621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1597313923, states[0] = -56.973975, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1610750659, states[0] = 6.432297, states[40]= 0.005405
Saving checkpoint... 
Iteration: 1624225984, states[0] = 18.004713, states[40]= 0.007622
Saving checkpoint... 
Iteration: 1637283044, states[0] = -95.224150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650741063, states[0] = -94.256919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1664198999, states[0] = -39.177663, states[40]= 0.000144
Saving checkpoint... 
Iteration: 1677649334, states[0] = 7.122549, states[40]= 0.005460
Saving checkpoint... 
Iteration: 1691157736, states[0] = 2.201835, states[40]= 0.005022
Saving checkpoint... 
Iteration: 1704588435, states[0] = -95.360314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1718002350, states[0] = -95.262990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1731465071, states[0] = -95.181713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1744944601, states[0] = -94.853836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1757742773, states[0] = 10.546978, states[40]= 0.005746
Saving checkpoint... 
Iteration: 1769875415, states[0] = -95.207705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1783364514, states[0] = -95.180187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1796861918, states[0] = -95.172778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810294472, states[0] = -95.066590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1823770920, states[0] = -95.032263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837211637, states[0] = -94.940175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850693852, states[0] = -94.897549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1864190391, states[0] = -94.884725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1877700371, states[0] = -94.901638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890979224, states[0] = -95.089409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904472502, states[0] = -95.086822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1917906317, states[0] = -95.072661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931338541, states[0] = -95.046784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944127907, states[0] = -48.885341, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1955890819, states[0] = -95.066660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1969346246, states[0] = -95.049431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1982829786, states[0] = -95.040896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1996308121, states[0] = -95.027492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009663313, states[0] = -93.544416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023162443, states[0] = -93.167517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2036644006, states[0] = -67.398375, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2049950345, states[0] = -95.079802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2061398693, states[0] = -95.068154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073210346, states[0] = -94.912786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084879141, states[0] = -95.062024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096590477, states[0] = -11.984163, states[40]= 0.001934
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.962546
 - CaMKt in component CaMK (millimolar): 0.007022
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.643663
 - nass in component intracellular_ions (millimolar): 6.643724
 - ki in component intracellular_ions (millimolar): 145.333146
 - kss in component intracellular_ions (millimolar): 145.333126
 - cansr in component intracellular_ions (millimolar): 1.313116
 - cajsr in component intracellular_ions (millimolar): 1.275201
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003596
 - hf in component INa (dimensionless): 0.881050
 - hs in component INa (dimensionless): 0.881046
 - j in component INa (dimensionless): 0.881019
 - hsp in component INa (dimensionless): 0.727812
 - jp in component INa (dimensionless): 0.881000
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.712022
 - hLp in component INaL (dimensionless): 0.455313
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.623901
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.699632
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938352
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999895
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001599
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.320790
 - xs1 in component IKs (dimensionless): 0.237124
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997321
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:55:35 (9352): called boinc_finish(0)

</stderr_txt>
]]>


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