𝕏

Task 55315590

Name HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_965_0
Workunit 26266913
Created 29 Jun 2024, 9:35:54 UTC
Sent 29 Jun 2024, 18:15:37 UTC
Report deadline 3 Jul 2024, 3:51:37 UTC
Received 29 Jun 2024, 19:28:28 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237422
Run time 53 min 35 sec
CPU time 53 min 33 sec
Validate state Valid
Credit 59.24
Device peak FLOPS 5.47 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.61 MB
Peak swap size 6.24 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_965.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_965_0_r580083725_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_965_0_r580083725_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 91.834666
     * GNaL_b in INaL: 0.004683
     * Gto_b in Ito: 0.074963
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033041
     * GKs_b in IKs: 0.001919
     * GK1_b in IK1: 0.181204
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 68.701320
     * GKb_b in IKb: 0.003680
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.051563
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12519476, states[0] = 20.737095, states[40]= 0.010604
Saving checkpoint... 
Iteration: 25317953, states[0] = -95.062538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37815951, states[0] = -95.047943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50228923, states[0] = -94.965590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62706451, states[0] = -94.927376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75262302, states[0] = -94.991993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87016170, states[0] = 22.124246, states[40]= 0.015594
Saving checkpoint... 
Iteration: 99505678, states[0] = 27.611666, states[40]= 0.124858
Saving checkpoint... 
Iteration: 112011317, states[0] = 23.322953, states[40]= 0.037996
Saving checkpoint... 
Iteration: 124531839, states[0] = 17.625574, states[40]= 0.006088
Saving checkpoint... 
Iteration: 137064508, states[0] = 3.803777, states[40]= 0.004687
Saving checkpoint... 
Iteration: 149680612, states[0] = -94.869750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161857779, states[0] = -95.039805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174111056, states[0] = -36.179820, states[40]= 0.000199
Saving checkpoint... 
Iteration: 186620579, states[0] = -46.302669, states[40]= 0.000045
Saving checkpoint... 
Iteration: 199124068, states[0] = -50.188222, states[40]= 0.000024
Saving checkpoint... 
Iteration: 211609329, states[0] = -34.376472, states[40]= 0.000253
Saving checkpoint... 
Iteration: 224192304, states[0] = -94.890514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236679405, states[0] = -94.866389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248681538, states[0] = -94.870547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261108095, states[0] = -33.101822, states[40]= 0.000297
Saving checkpoint... 
Iteration: 273668961, states[0] = -94.834149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286263737, states[0] = -94.984403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299036972, states[0] = 15.758606, states[40]= 0.005597
Saving checkpoint... 
Iteration: 311624605, states[0] = -50.775805, states[40]= 0.000022
Saving checkpoint... 
Iteration: 324015596, states[0] = 22.312850, states[40]= 0.017032
Saving checkpoint... 
Iteration: 336227291, states[0] = -94.944521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348846598, states[0] = -95.034839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361560085, states[0] = 5.988456, states[40]= 0.004832
Saving checkpoint... 
Iteration: 374128709, states[0] = -55.500024, states[40]= 0.000010
Saving checkpoint... 
Iteration: 386732920, states[0] = -94.951656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399305238, states[0] = -95.014763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411073427, states[0] = -1.117215, states[40]= 0.004126
Saving checkpoint... 
Iteration: 423668625, states[0] = -94.831804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436250429, states[0] = -94.971456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448726169, states[0] = -94.942976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461011651, states[0] = 23.250922, states[40]= 0.035394
Saving checkpoint... 
Iteration: 473530466, states[0] = 18.136306, states[40]= 0.006274
Saving checkpoint... 
Iteration: 485652292, states[0] = -91.161436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497749027, states[0] = -94.969962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510328663, states[0] = -95.027038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522821361, states[0] = -95.023486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535498355, states[0] = -95.066491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548005981, states[0] = 27.112847, states[40]= 0.118674
Saving checkpoint... 
Iteration: 560508014, states[0] = 24.859282, states[40]= 0.079203
Saving checkpoint... 
Iteration: 572250595, states[0] = -94.971550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584856011, states[0] = -95.038246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597272628, states[0] = -94.991859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609780037, states[0] = -94.997712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617800808, states[0] = -95.011966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630761158, states[0] = -94.981838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644102604, states[0] = -27.500845, states[40]= 0.000535
Saving checkpoint... 
Iteration: 657397287, states[0] = -95.050488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670705954, states[0] = -94.913282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684029921, states[0] = 18.323104, states[40]= 0.006356
Saving checkpoint... 
Iteration: 697119086, states[0] = -44.637750, states[40]= 0.000058
Saving checkpoint... 
Iteration: 709402122, states[0] = -95.051610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722715520, states[0] = -94.927951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736202069, states[0] = -94.906912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749339683, states[0] = -95.031798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762726046, states[0] = -94.942636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776119180, states[0] = -44.740124, states[40]= 0.000057
Saving checkpoint... 
Iteration: 789031869, states[0] = 17.645853, states[40]= 0.006085
Saving checkpoint... 
Iteration: 802333371, states[0] = -95.029030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815580356, states[0] = -5.999323, states[40]= 0.003214
Saving checkpoint... 
Iteration: 828901014, states[0] = -95.051284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842593409, states[0] = -18.176421, states[40]= 0.001099
Saving checkpoint... 
Iteration: 855719838, states[0] = -94.934093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869014443, states[0] = 22.569891, states[40]= 0.020578
Saving checkpoint... 
Iteration: 881832596, states[0] = -95.028637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895062522, states[0] = 4.826038, states[40]= 0.004760
Saving checkpoint... 
Iteration: 908295671, states[0] = -95.008551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921998194, states[0] = -95.066260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935333105, states[0] = -95.028836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948560265, states[0] = 5.904157, states[40]= 0.004828
Saving checkpoint... 
Iteration: 961681692, states[0] = -94.870386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974882732, states[0] = -95.046513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988441790, states[0] = -95.059173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001587589, states[0] = -12.399797, states[40]= 0.001894
Saving checkpoint... 
Iteration: 1014910221, states[0] = -95.053255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028498501, states[0] = -95.066229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041678127, states[0] = -94.863254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054233485, states[0] = -94.951977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067764577, states[0] = -94.984699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080871032, states[0] = -95.043001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093934054, states[0] = -95.057824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107448042, states[0] = -95.060084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120646658, states[0] = -82.062500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133617026, states[0] = -42.411688, states[40]= 0.000081
Saving checkpoint... 
Iteration: 1146894962, states[0] = -95.049642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159857573, states[0] = -95.038482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173072251, states[0] = -0.394474, states[40]= 0.004232
Saving checkpoint... 
Iteration: 1186056240, states[0] = 7.749259, states[40]= 0.004924
Saving checkpoint... 
Iteration: 1198911380, states[0] = -95.053401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211669953, states[0] = -94.839185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224554244, states[0] = 8.634791, states[40]= 0.004966
Saving checkpoint... 
Iteration: 1237814975, states[0] = -95.019770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250988671, states[0] = -95.065133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264150587, states[0] = -89.021957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277273305, states[0] = -94.992032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289771721, states[0] = -94.990722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301915765, states[0] = -95.054260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314627173, states[0] = -53.712538, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1327331031, states[0] = -95.027677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339993751, states[0] = -95.065597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352755418, states[0] = -94.975965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365417354, states[0] = -95.054548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377214019, states[0] = -94.925361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390039908, states[0] = 14.614011, states[40]= 0.005411
Saving checkpoint... 
Iteration: 1402915049, states[0] = -95.054057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415437223, states[0] = -95.058184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428081133, states[0] = -6.623687, states[40]= 0.003081
Saving checkpoint... 
Iteration: 1440725821, states[0] = -94.941956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453189781, states[0] = -94.885173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465342652, states[0] = -95.032629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477186689, states[0] = -94.879504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489781870, states[0] = -94.998602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502441633, states[0] = 11.889722, states[40]= 0.005979
Saving checkpoint... 
Iteration: 1515071672, states[0] = -8.773511, states[40]= 0.002902
Saving checkpoint... 
Iteration: 1527437386, states[0] = -94.184651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539387132, states[0] = -27.420124, states[40]= 0.000547
Saving checkpoint... 
Iteration: 1552138702, states[0] = -95.257169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564904664, states[0] = -48.883000, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1577488946, states[0] = -30.306113, states[40]= 0.000412
Saving checkpoint... 
Iteration: 1590305735, states[0] = 28.581903, states[40]= 0.110323
Saving checkpoint... 
Iteration: 1602919957, states[0] = 20.861893, states[40]= 0.011457
Saving checkpoint... 
Iteration: 1615151270, states[0] = -95.278715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1627723294, states[0] = -95.250755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640742100, states[0] = 10.726536, states[40]= 0.005997
Saving checkpoint... 
Iteration: 1653586951, states[0] = -95.305441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666601339, states[0] = -45.302871, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1679548514, states[0] = -95.107248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1692403553, states[0] = -48.061904, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1704660116, states[0] = -0.274053, states[40]= 0.004756
Saving checkpoint... 
Iteration: 1717699683, states[0] = -95.219666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1730550295, states[0] = -95.115970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743636643, states[0] = 13.544396, states[40]= 0.006427
Saving checkpoint... 
Iteration: 1756701377, states[0] = -95.222265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1769763909, states[0] = -3.239450, states[40]= 0.004212
Saving checkpoint... 
Iteration: 1782263465, states[0] = -95.290010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794970305, states[0] = -9.255086, states[40]= 0.002822
Saving checkpoint... 
Iteration: 1807854345, states[0] = -95.076651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1820811034, states[0] = -95.046576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833777980, states[0] = -95.016012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846752433, states[0] = -94.986930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1859616310, states[0] = -42.427753, states[40]= 0.000081
Saving checkpoint... 
Iteration: 1871916013, states[0] = -95.060652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1884844607, states[0] = -95.037746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897590317, states[0] = -15.285857, states[40]= 0.001437
Saving checkpoint... 
Iteration: 1910529945, states[0] = 18.283788, states[40]= 0.006350
Saving checkpoint... 
Iteration: 1923551116, states[0] = 9.959621, states[40]= 0.005031
Saving checkpoint... 
Iteration: 1936638371, states[0] = -67.938826, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1949059509, states[0] = 6.239815, states[40]= 0.004847
Saving checkpoint... 
Iteration: 1961720185, states[0] = -94.934415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1974559989, states[0] = 6.025164, states[40]= 0.004835
Saving checkpoint... 
Iteration: 1987371328, states[0] = -95.042772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2000066088, states[0] = 3.034283, states[40]= 0.004621
Saving checkpoint... 
Iteration: 2013035372, states[0] = 16.364595, states[40]= 0.005723
Saving checkpoint... 
Iteration: 2025896248, states[0] = -95.049497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038253364, states[0] = -94.973550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051255803, states[0] = -94.975940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2064162449, states[0] = -94.709187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2077098181, states[0] = -23.011908, states[40]= 0.000755
Saving checkpoint... 
Iteration: 2090079984, states[0] = -5.706114, states[40]= 0.003276
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.941608
 - CaMKt in component CaMK (millimolar): 0.006513
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.625463
 - nass in component intracellular_ions (millimolar): 6.625520
 - ki in component intracellular_ions (millimolar): 145.358422
 - kss in component intracellular_ions (millimolar): 145.358404
 - cansr in component intracellular_ions (millimolar): 1.286018
 - cajsr in component intracellular_ions (millimolar): 1.249176
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003604
 - hf in component INa (dimensionless): 0.880689
 - hs in component INa (dimensionless): 0.880685
 - j in component INa (dimensionless): 0.880662
 - hsp in component INa (dimensionless): 0.727134
 - jp in component INa (dimensionless): 0.880647
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.713084
 - hLp in component INaL (dimensionless): 0.459726
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.629655
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.706229
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.939227
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999901
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001506
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.318323
 - xs1 in component IKs (dimensionless): 0.230557
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997327
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:28:21 (2800): called boinc_finish(0)

</stderr_txt>
]]>


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