𝕏

Task 55313426

Name HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_143_1
Workunit 26265831
Created 29 Jun 2024, 9:34:51 UTC
Sent 29 Jun 2024, 17:57:52 UTC
Report deadline 3 Jul 2024, 3:33:52 UTC
Received 30 Jun 2024, 7:16:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239773
Run time 1 hours 54 min 15 sec
CPU time 51 min 46 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 5.91 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.44 MB
Peak swap size 5.50 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_143.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_143_1_r844136438_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_143_1_r844136438_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 92.965760
     * GNaL_b in INaL: 0.007484
     * Gto_b in Ito: 0.088936
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030861
     * GKs_b in IKs: 0.001994
     * GK1_b in IK1: 0.181888
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 69.281788
     * GKb_b in IKb: 0.003668
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050674
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 36655420, states[0] = -70.946630, states[40]= 0.000001
Saving checkpoint... 
Iteration: 73794271, states[0] = -94.995196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106719675, states[0] = -94.906897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141418690, states[0] = -95.041798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177542752, states[0] = 16.115372, states[40]= 0.004862
Saving checkpoint... 
Iteration: 212584601, states[0] = -1.425008, states[40]= 0.003946
Saving checkpoint... 
Iteration: 246680107, states[0] = -94.733428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281275716, states[0] = -94.972084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316615261, states[0] = -26.018108, states[40]= 0.000725
Saving checkpoint... 
Iteration: 354094994, states[0] = -8.529236, states[40]= 0.002573
Saving checkpoint... 
Iteration: 389252982, states[0] = -94.948830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424559443, states[0] = 10.169681, states[40]= 0.004748
Saving checkpoint... 
Iteration: 460841327, states[0] = -95.015165, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_143.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_143_1_r844136438_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_143_1_r844136438_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 92.965760
     * GNaL_b in INaL: 0.007484
     * Gto_b in Ito: 0.088936
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030861
     * GKs_b in IKs: 0.001994
     * GK1_b in IK1: 0.181888
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 69.281788
     * GKb_b in IKb: 0.003668
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050674
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 460841327
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.015165 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 467757851, states[0] = -94.954198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474044278, states[0] = 15.610324, states[40]= 0.004832
Saving checkpoint... 
Iteration: 480779803, states[0] = -94.975539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488553778, states[0] = 12.277115, states[40]= 0.004763
Saving checkpoint... 
Iteration: 496225946, states[0] = -94.913301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503840208, states[0] = -95.014610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511623214, states[0] = -33.083365, states[40]= 0.000371
Saving checkpoint... 
Iteration: 519366660, states[0] = -95.025577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527129781, states[0] = -39.136869, states[40]= 0.000165
Saving checkpoint... 
Iteration: 534939518, states[0] = -95.044696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542839018, states[0] = -95.014018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550573201, states[0] = 4.452042, states[40]= 0.004557
Saving checkpoint... 
Iteration: 558415033, states[0] = -95.039653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566133692, states[0] = -42.934830, states[40]= 0.000094
Saving checkpoint... 
Iteration: 573821503, states[0] = -95.004883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581710793, states[0] = -94.889188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589548066, states[0] = 14.309684, states[40]= 0.004788
Saving checkpoint... 
Iteration: 597340314, states[0] = -95.014592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605105057, states[0] = -17.051605, states[40]= 0.001209
Saving checkpoint... 
Iteration: 612835732, states[0] = -95.012375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620606696, states[0] = -18.494283, states[40]= 0.001088
Saving checkpoint... 
Iteration: 628481229, states[0] = -95.050923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636256236, states[0] = -94.952305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644205475, states[0] = -94.880030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651937950, states[0] = -95.044323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659635494, states[0] = -44.748505, states[40]= 0.000072
Saving checkpoint... 
Iteration: 667476995, states[0] = -95.050363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675169071, states[0] = -90.826775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682830431, states[0] = -95.009646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690544070, states[0] = 15.680511, states[40]= 0.004836
Saving checkpoint... 
Iteration: 698282297, states[0] = -94.977514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706088243, states[0] = -3.674620, states[40]= 0.003566
Saving checkpoint... 
Iteration: 713793528, states[0] = -94.986459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721648460, states[0] = -58.945158, states[40]= 0.000007
Saving checkpoint... 
Iteration: 729439700, states[0] = -95.044588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737232555, states[0] = -94.922667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745007409, states[0] = 24.103664, states[40]= 0.095756
Saving checkpoint... 
Iteration: 752650882, states[0] = -61.873650, states[40]= 0.000004
Saving checkpoint... 
Iteration: 759535874, states[0] = 18.309104, states[40]= 0.005117
Saving checkpoint... 
Iteration: 767131957, states[0] = -41.227433, states[40]= 0.000122
Saving checkpoint... 
Iteration: 774967888, states[0] = -95.049066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782631651, states[0] = -40.930146, states[40]= 0.000127
Saving checkpoint... 
Iteration: 790089321, states[0] = -4.388889, states[40]= 0.003430
Saving checkpoint... 
Iteration: 796344812, states[0] = -95.016517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802805710, states[0] = -94.995014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809165113, states[0] = -84.689650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815629480, states[0] = -38.851550, states[40]= 0.000172
Saving checkpoint... 
Iteration: 821870849, states[0] = -95.026852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827740480, states[0] = -94.933280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833701409, states[0] = -94.872698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839714798, states[0] = -94.895641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846089001, states[0] = -4.174462, states[40]= 0.003471
Saving checkpoint... 
Iteration: 852287472, states[0] = -94.981657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858262532, states[0] = -94.958881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864274681, states[0] = -94.970702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870084742, states[0] = -1.503049, states[40]= 0.003934
Saving checkpoint... 
Iteration: 876320727, states[0] = -95.004221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882754579, states[0] = -94.950278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888966158, states[0] = -95.048740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894704535, states[0] = -94.878202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901242311, states[0] = -94.935578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907108818, states[0] = -20.361238, states[40]= 0.000972
Saving checkpoint... 
Iteration: 912950479, states[0] = -95.046323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919140880, states[0] = -50.408763, states[40]= 0.000030
Saving checkpoint... 
Iteration: 924964185, states[0] = -95.048431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931434471, states[0] = -95.043465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937613889, states[0] = -24.811976, states[40]= 0.000779
Saving checkpoint... 
Iteration: 943670819, states[0] = -92.444074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949834474, states[0] = -95.011507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956042514, states[0] = 16.200665, states[40]= 0.004867
Saving checkpoint... 
Iteration: 961978366, states[0] = -95.050324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967742262, states[0] = -94.935467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973594921, states[0] = -8.471613, states[40]= 0.002585
Saving checkpoint... 
Iteration: 978871402, states[0] = -95.026931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008277766, states[0] = -94.973371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042980868, states[0] = -95.050578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079218698, states[0] = -94.901740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116892787, states[0] = -95.033558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159833814, states[0] = -95.011024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201625842, states[0] = -35.469203, states[40]= 0.000274
Saving checkpoint... 
Iteration: 1244634304, states[0] = -43.545696, states[40]= 0.000086
Saving checkpoint... 
Iteration: 1285292161, states[0] = -94.985007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327149491, states[0] = -60.174116, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1373041988, states[0] = 16.374640, states[40]= 0.004879
Saving checkpoint... 
Iteration: 1415624417, states[0] = -34.170543, states[40]= 0.000324
Saving checkpoint... 
Iteration: 1458975058, states[0] = -95.049538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502233203, states[0] = -64.906324, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1545452065, states[0] = -94.665845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1586325873, states[0] = -95.228733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628043778, states[0] = -95.252583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673347815, states[0] = -95.257472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717832580, states[0] = 17.320181, states[40]= 0.006332
Saving checkpoint... 
Iteration: 1759279182, states[0] = -9.652594, states[40]= 0.002687
Saving checkpoint... 
Iteration: 1803585002, states[0] = -4.031975, states[40]= 0.003658
Saving checkpoint... 
Iteration: 1846089444, states[0] = -5.150444, states[40]= 0.003296
Saving checkpoint... 
Iteration: 1889501584, states[0] = 45.597337, states[40]= 0.078492
Saving checkpoint... 
Iteration: 1931245158, states[0] = -94.939493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1972164333, states[0] = -83.264372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013265043, states[0] = -94.960633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2054264508, states[0] = -94.959989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2094951013, states[0] = -95.045486, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.927777
 - CaMKt in component CaMK (millimolar): 0.007366
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.657328
 - nass in component intracellular_ions (millimolar): 6.657387
 - ki in component intracellular_ions (millimolar): 145.316323
 - kss in component intracellular_ions (millimolar): 145.316304
 - cansr in component intracellular_ions (millimolar): 1.325789
 - cajsr in component intracellular_ions (millimolar): 1.286465
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003609
 - hf in component INa (dimensionless): 0.880450
 - hs in component INa (dimensionless): 0.880446
 - j in component INa (dimensionless): 0.880420
 - hsp in component INa (dimensionless): 0.726680
 - jp in component INa (dimensionless): 0.880403
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.708703
 - hLp in component INaL (dimensionless): 0.447272
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.612025
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.685236
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.927460
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999858
 - jca in component ICaL (dimensionless): 0.999972
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001647
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.335851
 - xs1 in component IKs (dimensionless): 0.258538
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997330
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:01:39 (14148): called boinc_finish(0)

</stderr_txt>
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