𝕏

Task 55307990

Name HuVeMOp_20240629112358674907_ORdGradInc_k_25-Schmidt_750-conf_932_1
Workunit 26263114
Created 29 Jun 2024, 9:32:14 UTC
Sent 29 Jun 2024, 17:20:56 UTC
Report deadline 2 Jul 2024, 17:20:56 UTC
Received 30 Jun 2024, 2:33:52 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 34 min 24 sec
CPU time 1 hours 33 min
Validate state Valid
Credit 42.96
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.85 MB
Peak swap size 4.13 GB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Schmidt_750-conf_932.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Schmidt_750-conf_932_1_r1454157355_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Schmidt_750-conf_932_1_r1454157355_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 91.816507
     * GNaL_b in INaL: 0.005018
     * Gto_b in Ito: 0.072705
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032901
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.150357
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 65.922271
     * GKb_b in IKb: 0.003683
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037986
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4000.000000
     * CL_0 in membrane: 750.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499625000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12992740, states[0] = -84.322243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26242786, states[0] = -84.600985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 39405646, states[0] = 27.768054, states[40]= 0.000044
Saving checkpoint... 
Iteration: 52517698, states[0] = 31.816676, states[40]= 0.003868
Saving checkpoint... 
Iteration: 65658235, states[0] = 26.673027, states[40]= 0.000021
Saving checkpoint... 
Iteration: 77735270, states[0] = -29.558471, states[40]= 0.000138
Saving checkpoint... 
Iteration: 90132395, states[0] = -53.452024, states[40]= 0.000013
Saving checkpoint... 
Iteration: 102627139, states[0] = -84.328976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115484715, states[0] = -84.592640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 128723941, states[0] = -16.719814, states[40]= 0.000180
Saving checkpoint... 
Iteration: 140583238, states[0] = -84.554640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 152993472, states[0] = -84.602330, states[40]= 0.000001
Saving checkpoint... 
Iteration: 165368496, states[0] = -84.602161, states[40]= 0.000001
Saving checkpoint... 
Iteration: 179367934, states[0] = -37.964681, states[40]= 0.000079
Saving checkpoint... 
Iteration: 192585652, states[0] = -84.092473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205575391, states[0] = 4.619847, states[40]= 0.000161
Saving checkpoint... 
Iteration: 218761883, states[0] = -58.371754, states[40]= 0.000007
Saving checkpoint... 
Iteration: 232144986, states[0] = 31.354368, states[40]= 0.001721
Saving checkpoint... 
Iteration: 244544389, states[0] = 21.544385, states[40]= 0.000013
Saving checkpoint... 
Iteration: 257497315, states[0] = -84.304816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269447344, states[0] = -83.989073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282699800, states[0] = -84.537469, states[40]= 0.000001
Saving checkpoint... 
Iteration: 295575807, states[0] = 4.353863, states[40]= 0.000165
Saving checkpoint... 
Iteration: 308219296, states[0] = -84.568841, states[40]= 0.000001
Saving checkpoint... 
Iteration: 320420426, states[0] = -83.576292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332669744, states[0] = 21.373370, states[40]= 0.000014
Saving checkpoint... 
Iteration: 345712798, states[0] = -84.558318, states[40]= 0.000001
Saving checkpoint... 
Iteration: 359206916, states[0] = -84.548512, states[40]= 0.000001
Saving checkpoint... 
Iteration: 371640409, states[0] = 32.058137, states[40]= 0.008714
Saving checkpoint... 
Iteration: 384711715, states[0] = -84.555880, states[40]= 0.000001
Saving checkpoint... 
Iteration: 397002558, states[0] = -84.325758, states[40]= 0.000001
Saving checkpoint... 
Iteration: 409371319, states[0] = -84.297281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421692970, states[0] = -83.949325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434168376, states[0] = -84.465125, states[40]= 0.000001
Saving checkpoint... 
Iteration: 445614636, states[0] = -34.382951, states[40]= 0.000106
Saving checkpoint... 
Iteration: 459537265, states[0] = -82.537603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472581469, states[0] = 0.484276, states[40]= 0.000228
Saving checkpoint... 
Iteration: 485488175, states[0] = -84.255586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499221856, states[0] = -14.291936, states[40]= 0.000204
Saving checkpoint... 
Iteration: 511831250, states[0] = -84.544536, states[40]= 0.000001
Saving checkpoint... 
Iteration: 525025320, states[0] = 29.778289, states[40]= 0.000263
Saving checkpoint... 
Iteration: 536673762, states[0] = 19.400914, states[40]= 0.000020
Saving checkpoint... 
Iteration: 549695793, states[0] = -84.524983, states[40]= 0.000001
Saving checkpoint... 
Iteration: 561611807, states[0] = -84.246976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574460576, states[0] = -84.550514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 587478661, states[0] = -84.201330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599482006, states[0] = -84.220175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612044774, states[0] = 21.361013, states[40]= 0.000014
Saving checkpoint... 
Iteration: 625299403, states[0] = -83.712266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638168261, states[0] = -84.460986, states[40]= 0.000001
Saving checkpoint... 
Iteration: 650550285, states[0] = -84.478649, states[40]= 0.000001
Saving checkpoint... 
Iteration: 663158662, states[0] = -81.193589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675931849, states[0] = -83.835990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688560767, states[0] = 13.157654, states[40]= 0.000054
Saving checkpoint... 
Iteration: 701579978, states[0] = -84.538819, states[40]= 0.000001
Saving checkpoint... 
Iteration: 713982965, states[0] = -84.579683, states[40]= 0.000001
Saving checkpoint... 
Iteration: 727269421, states[0] = -67.009132, states[40]= 0.000002
Saving checkpoint... 
Iteration: 740474279, states[0] = -84.172244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753162332, states[0] = -82.545039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766274354, states[0] = -72.925312, states[40]= 0.000001
Saving checkpoint... 
Iteration: 778975093, states[0] = -18.050705, states[40]= 0.000169
Saving checkpoint... 
Iteration: 791727907, states[0] = -21.303167, states[40]= 0.000154
Saving checkpoint... 
Iteration: 807491032, states[0] = -35.889132, states[40]= 0.000095
Saving checkpoint... 
Iteration: 824748983, states[0] = -44.441816, states[40]= 0.000040
Saving checkpoint... 
Iteration: 839927924, states[0] = -84.481441, states[40]= 0.000001
Saving checkpoint... 
Iteration: 852715079, states[0] = -84.552387, states[40]= 0.000001
Saving checkpoint... 
Iteration: 865921109, states[0] = 20.713289, states[40]= 0.000015
Saving checkpoint... 
Iteration: 878847759, states[0] = -84.160199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891845602, states[0] = -12.836012, states[40]= 0.000221
Saving checkpoint... 
Iteration: 904653099, states[0] = -77.021910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917131054, states[0] = -84.330810, states[40]= 0.000001
Saving checkpoint... 
Iteration: 930041764, states[0] = 22.804310, states[40]= 0.000011
Saving checkpoint... 
Iteration: 943362880, states[0] = -84.245325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955982677, states[0] = -26.693835, states[40]= 0.000146
Saving checkpoint... 
Iteration: 968834529, states[0] = -84.069484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981972294, states[0] = -84.155315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994051467, states[0] = -84.475070, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1007236181, states[0] = -84.578145, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1019978895, states[0] = -84.568795, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1033087473, states[0] = -84.544971, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1046683524, states[0] = 14.369387, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1058249284, states[0] = -84.591782, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1072357876, states[0] = -84.215983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087470007, states[0] = -84.555331, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1103454158, states[0] = -84.026929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116999175, states[0] = -84.297038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129203124, states[0] = 2.840352, states[40]= 0.000190
Saving checkpoint... 
Iteration: 1141719400, states[0] = -84.133801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153902448, states[0] = 29.013246, states[40]= 0.000126
Saving checkpoint... 
Iteration: 1167048198, states[0] = 19.686394, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1179541550, states[0] = -83.263349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192215926, states[0] = -7.713299, states[40]= 0.000271
Saving checkpoint... 
Iteration: 1204694278, states[0] = -83.945330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218144952, states[0] = -67.617552, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1230932811, states[0] = -83.836148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243495799, states[0] = -84.584663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1256241217, states[0] = -84.579373, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1268181186, states[0] = -84.480983, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1281184419, states[0] = -83.852582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294553724, states[0] = 16.891151, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1307037683, states[0] = -82.614013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319822105, states[0] = -83.966753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333036673, states[0] = -84.429698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1346191296, states[0] = -84.501225, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1359505599, states[0] = -51.505741, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1371855497, states[0] = -24.232997, states[40]= 0.000149
Saving checkpoint... 
Iteration: 1383925998, states[0] = -83.732983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396680855, states[0] = -83.809613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409184119, states[0] = -84.484906, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1422412714, states[0] = 24.688686, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1434764879, states[0] = 32.088933, states[40]= 0.010514
Saving checkpoint... 
Iteration: 1447402329, states[0] = -84.399065, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1460473240, states[0] = -84.152041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472990715, states[0] = -84.574765, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1485881594, states[0] = -52.569622, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1498272923, states[0] = -71.178018, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.460128
 - CaMKt in component CaMK (millimolar): 0.029103
 - cass in component intracellular_ions (millimolar): 0.000098
 - nai in component intracellular_ions (millimolar): 6.835119
 - nass in component intracellular_ions (millimolar): 6.835258
 - ki in component intracellular_ions (millimolar): 144.884359
 - kss in component intracellular_ions (millimolar): 144.884333
 - cansr in component intracellular_ions (millimolar): 1.912992
 - cajsr in component intracellular_ions (millimolar): 1.743423
 - cai in component intracellular_ions (millimolar): 0.000099
 - m in component INa (dimensionless): 0.010351
 - hf in component INa (dimensionless): 0.568747
 - hs in component INa (dimensionless): 0.568636
 - j in component INa (dimensionless): 0.568045
 - hsp in component INa (dimensionless): 0.322249
 - jp in component INa (dimensionless): 0.567607
 - mL in component INaL (dimensionless): 0.000360
 - hL in component INaL (dimensionless): 0.360584
 - hLp in component INaL (dimensionless): 0.160868
 - a in component Ito (dimensionless): 0.001260
 - iF in component Ito (dimensionless): 0.999189
 - iS in component Ito (dimensionless): 0.419705
 - ap in component Ito (dimensionless): 0.000642
 - iFp in component Ito (dimensionless): 0.999189
 - iSp in component Ito (dimensionless): 0.456767
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.867117
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.998091
 - jca in component ICaL (dimensionless): 0.999358
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004706
 - xrf in component IKr (dimensionless): 0.000097
 - xrs in component IKr (dimensionless): 0.627064
 - xs1 in component IKs (dimensionless): 0.349746
 - xs2 in component IKs (dimensionless): 0.000283
 - xk1 in component IK1 (dimensionless): 0.996810
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
21:55:09 (90444): called boinc_finish(0)

</stderr_txt>
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