𝕏

Task 55307979

Name HuVeMOp_20240629112358674907_ORdGradInc_k_25-Schmidt_666-conf_732_0
Workunit 26263109
Created 29 Jun 2024, 9:32:14 UTC
Sent 29 Jun 2024, 17:20:56 UTC
Report deadline 2 Jul 2024, 17:21:00 UTC
Received 30 Jun 2024, 2:33:52 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 36 min 4 sec
CPU time 1 hours 33 min 51 sec
Validate state Valid
Credit 42.99
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.86 MB
Peak swap size 4.13 GB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Schmidt_666-conf_732.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Schmidt_666-conf_732_0_r321236634_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Schmidt_666-conf_732_0_r321236634_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 116.989383
     * GNaL_b in INaL: 0.007416
     * Gto_b in Ito: 0.099638
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033652
     * GKs_b in IKs: 0.001853
     * GK1_b in IK1: 0.174363
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 74.481788
     * GKb_b in IKb: 0.003923
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.021209
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12369638, states[0] = 24.817152, states[40]= 0.000040
Saving checkpoint... 
Iteration: 23749210, states[0] = -0.612612, states[40]= 0.000368
Saving checkpoint... 
Iteration: 36459090, states[0] = -47.853793, states[40]= 0.000043
Saving checkpoint... 
Iteration: 48682522, states[0] = 30.876940, states[40]= 0.018865
Saving checkpoint... 
Iteration: 61761793, states[0] = -11.186907, states[40]= 0.000307
Saving checkpoint... 
Iteration: 73333360, states[0] = -84.862277, states[40]= 0.000001
Saving checkpoint... 
Iteration: 86205640, states[0] = -84.418689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98519860, states[0] = -84.264997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111047738, states[0] = 22.350026, states[40]= 0.000011
Saving checkpoint... 
Iteration: 122789578, states[0] = -39.713560, states[40]= 0.000100
Saving checkpoint... 
Iteration: 134668418, states[0] = -84.859648, states[40]= 0.000001
Saving checkpoint... 
Iteration: 147075376, states[0] = 8.499558, states[40]= 0.000123
Saving checkpoint... 
Iteration: 159355015, states[0] = 30.907185, states[40]= 0.017001
Saving checkpoint... 
Iteration: 172335578, states[0] = -84.856941, states[40]= 0.000001
Saving checkpoint... 
Iteration: 185127548, states[0] = -41.440697, states[40]= 0.000084
Saving checkpoint... 
Iteration: 197195953, states[0] = -84.300941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209781795, states[0] = -25.993730, states[40]= 0.000200
Saving checkpoint... 
Iteration: 221928879, states[0] = -84.674587, states[40]= 0.000001
Saving checkpoint... 
Iteration: 234970687, states[0] = -84.793223, states[40]= 0.000001
Saving checkpoint... 
Iteration: 246813139, states[0] = -60.385615, states[40]= 0.000008
Saving checkpoint... 
Iteration: 259814582, states[0] = -61.409230, states[40]= 0.000007
Saving checkpoint... 
Iteration: 272226489, states[0] = -84.489720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284919695, states[0] = -84.623502, states[40]= 0.000001
Saving checkpoint... 
Iteration: 297098463, states[0] = -2.602370, states[40]= 0.000330
Saving checkpoint... 
Iteration: 309241044, states[0] = -84.560203, states[40]= 0.000001
Saving checkpoint... 
Iteration: 321615846, states[0] = -84.724066, states[40]= 0.000001
Saving checkpoint... 
Iteration: 334212975, states[0] = -84.377152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346726823, states[0] = 22.050083, states[40]= 0.000012
Saving checkpoint... 
Iteration: 360135788, states[0] = -40.855810, states[40]= 0.000089
Saving checkpoint... 
Iteration: 372569421, states[0] = -84.514468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386257918, states[0] = -84.620086, states[40]= 0.000001
Saving checkpoint... 
Iteration: 398542921, states[0] = -84.325043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411088682, states[0] = 8.439464, states[40]= 0.000122
Saving checkpoint... 
Iteration: 423701475, states[0] = 30.897839, states[40]= 0.017553
Saving checkpoint... 
Iteration: 436191659, states[0] = -84.138754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448312497, states[0] = -84.783565, states[40]= 0.000001
Saving checkpoint... 
Iteration: 461383991, states[0] = 28.506310, states[40]= 0.000126
Saving checkpoint... 
Iteration: 473736977, states[0] = 20.210170, states[40]= 0.000017
Saving checkpoint... 
Iteration: 486107006, states[0] = -1.813758, states[40]= 0.000317
Saving checkpoint... 
Iteration: 499058971, states[0] = 26.007524, states[40]= 0.000017
Saving checkpoint... 
Iteration: 511453633, states[0] = -14.368538, states[40]= 0.000261
Saving checkpoint... 
Iteration: 523630855, states[0] = -84.733884, states[40]= 0.000001
Saving checkpoint... 
Iteration: 536347712, states[0] = -84.839660, states[40]= 0.000001
Saving checkpoint... 
Iteration: 550022609, states[0] = -84.850510, states[40]= 0.000001
Saving checkpoint... 
Iteration: 563180831, states[0] = -82.313325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575579354, states[0] = -84.508505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588210519, states[0] = -84.249618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601259673, states[0] = -84.573727, states[40]= 0.000001
Saving checkpoint... 
Iteration: 613976799, states[0] = -84.753927, states[40]= 0.000001
Saving checkpoint... 
Iteration: 626446000, states[0] = -0.688914, states[40]= 0.000302
Saving checkpoint... 
Iteration: 639010243, states[0] = -84.822083, states[40]= 0.000001
Saving checkpoint... 
Iteration: 651916207, states[0] = -84.504947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664546004, states[0] = -84.233096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676709249, states[0] = 29.521198, states[40]= 0.099835
Saving checkpoint... 
Iteration: 688573778, states[0] = -84.436840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701661373, states[0] = -84.784136, states[40]= 0.000001
Saving checkpoint... 
Iteration: 714186696, states[0] = -81.415208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726165556, states[0] = -54.247846, states[40]= 0.000019
Saving checkpoint... 
Iteration: 738744888, states[0] = 22.776575, states[40]= 0.000011
Saving checkpoint... 
Iteration: 751106535, states[0] = 7.916915, states[40]= 0.000132
Saving checkpoint... 
Iteration: 763529779, states[0] = -83.664860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775553717, states[0] = -84.249092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787965043, states[0] = -84.689340, states[40]= 0.000001
Saving checkpoint... 
Iteration: 799743088, states[0] = 24.973029, states[40]= 0.000011
Saving checkpoint... 
Iteration: 812832331, states[0] = -49.199535, states[40]= 0.000036
Saving checkpoint... 
Iteration: 825828451, states[0] = -43.937815, states[40]= 0.000065
Saving checkpoint... 
Iteration: 838307847, states[0] = -84.710588, states[40]= 0.000001
Saving checkpoint... 
Iteration: 850936731, states[0] = -84.557539, states[40]= 0.000001
Saving checkpoint... 
Iteration: 863598667, states[0] = -84.529202, states[40]= 0.000001
Saving checkpoint... 
Iteration: 875973523, states[0] = -84.700758, states[40]= 0.000001
Saving checkpoint... 
Iteration: 889087760, states[0] = 21.822676, states[40]= 0.000012
Saving checkpoint... 
Iteration: 901921989, states[0] = -84.458902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914395741, states[0] = 31.013397, states[40]= 0.005888
Saving checkpoint... 
Iteration: 927240765, states[0] = -84.349052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939647609, states[0] = -84.712423, states[40]= 0.000001
Saving checkpoint... 
Iteration: 952713502, states[0] = -84.846985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 965106691, states[0] = 14.055065, states[40]= 0.000053
Saving checkpoint... 
Iteration: 977577313, states[0] = -84.353478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990124477, states[0] = 4.032706, states[40]= 0.000207
Saving checkpoint... 
Iteration: 1002245128, states[0] = -84.351898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015264649, states[0] = -84.478669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027826508, states[0] = -30.307214, states[40]= 0.000187
Saving checkpoint... 
Iteration: 1039769825, states[0] = 17.923762, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1051906427, states[0] = -84.289810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064428781, states[0] = 22.335763, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1080467531, states[0] = 0.248280, states[40]= 0.000285
Saving checkpoint... 
Iteration: 1102011232, states[0] = -84.767299, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1113272308, states[0] = -84.492514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126469804, states[0] = 0.269724, states[40]= 0.000284
Saving checkpoint... 
Iteration: 1138640701, states[0] = -84.650868, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1150762852, states[0] = 23.992952, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1162954722, states[0] = -84.562263, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1175271131, states[0] = -84.465646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187605018, states[0] = -84.464967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200546638, states[0] = -82.534377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213234407, states[0] = -84.165770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226025741, states[0] = -84.782425, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1239149855, states[0] = -6.667923, states[40]= 0.000344
Saving checkpoint... 
Iteration: 1252039835, states[0] = -84.806246, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1264521488, states[0] = -49.077123, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1277602447, states[0] = -84.417760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289485089, states[0] = -6.040586, states[40]= 0.000348
Saving checkpoint... 
Iteration: 1302595758, states[0] = -84.361794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315428629, states[0] = 27.808032, states[40]= 0.000065
Saving checkpoint... 
Iteration: 1328306426, states[0] = -84.604708, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1345216692, states[0] = -80.250601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362083906, states[0] = 31.037986, states[40]= 0.008065
Saving checkpoint... 
Iteration: 1379282736, states[0] = -84.469502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390585436, states[0] = -84.243264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402278579, states[0] = -84.436047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415229724, states[0] = -83.717951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427104862, states[0] = 26.228636, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1439403478, states[0] = -84.834460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1450741536, states[0] = 35.421024, states[40]= 0.924466
Saving checkpoint... 
Iteration: 1463784505, states[0] = 21.182466, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1476458039, states[0] = 18.075149, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1488412846, states[0] = 29.090805, states[40]= 0.361557
Total time: 3000150.000000
State Variables:
 - v in component membrane (millivolt): -84.711349
 - CaMKt in component CaMK (millimolar): 0.040097
 - cass in component intracellular_ions (millimolar): 0.000105
 - nai in component intracellular_ions (millimolar): 6.762737
 - nass in component intracellular_ions (millimolar): 6.762896
 - ki in component intracellular_ions (millimolar): 144.887434
 - kss in component intracellular_ions (millimolar): 144.887403
 - cansr in component intracellular_ions (millimolar): 2.098644
 - cajsr in component intracellular_ions (millimolar): 1.856346
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.010094
 - hf in component INa (dimensionless): 0.578841
 - hs in component INa (dimensionless): 0.578698
 - j in component INa (dimensionless): 0.577917
 - hsp in component INa (dimensionless): 0.331230
 - jp in component INa (dimensionless): 0.577278
 - mL in component INaL (dimensionless): 0.000344
 - hL in component INaL (dimensionless): 0.353204
 - hLp in component INaL (dimensionless): 0.155786
 - a in component Ito (dimensionless): 0.001239
 - iF in component Ito (dimensionless): 0.999223
 - iS in component Ito (dimensionless): 0.370159
 - ap in component Ito (dimensionless): 0.000632
 - iFp in component Ito (dimensionless): 0.999224
 - iSp in component Ito (dimensionless): 0.405981
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.844871
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.995929
 - jca in component ICaL (dimensionless): 0.998176
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.006155
 - xrf in component IKr (dimensionless): 0.000345
 - xrs in component IKr (dimensionless): 0.667162
 - xs1 in component IKs (dimensionless): 0.383154
 - xs2 in component IKs (dimensionless): 0.000276
 - xk1 in component IK1 (dimensionless): 0.996749
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
21:33:12 (90253): called boinc_finish(0)

</stderr_txt>
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