𝕏

Task 55302220

Name HuVeMOp_20240629112358674907_ORdGradInc_k_25-TESZT_Block_K1_75-conf_521_0
Workunit 26260231
Created 29 Jun 2024, 9:29:26 UTC
Sent 29 Jun 2024, 16:23:18 UTC
Report deadline 2 Jul 2024, 16:23:18 UTC
Received 1 Jul 2024, 5:40:08 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 3 hours 0 min 31 sec
CPU time 1 hours 29 min 16 sec
Validate state Valid
Credit 44.23
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-TESZT_Block_K1_75-conf_521.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-TESZT_Block_K1_75-conf_521_0_r1562527492_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-TESZT_Block_K1_75-conf_521_0_r1562527492_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 92.227529
     * GNaL_b in INaL: 0.004864
     * Gto_b in Ito: 0.070115
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032607
     * GKs_b in IKs: 0.001886
     * GK1_b in IK1: 0.037938
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 66.510629
     * GKb_b in IKb: 0.003717
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019678
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8408507, states[0] = -90.808196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17107491, states[0] = -23.370847, states[40]= 0.000971
Saving checkpoint... 
Iteration: 25466612, states[0] = -90.453239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32847622, states[0] = -90.015986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41166958, states[0] = -69.115388, states[40]= 0.000002
Saving checkpoint... 
Iteration: 49916818, states[0] = -90.211293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58184299, states[0] = -75.400352, states[40]= 0.000001
Saving checkpoint... 
Iteration: 66443327, states[0] = -90.222432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74970100, states[0] = -90.243455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83240307, states[0] = -86.378741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91917226, states[0] = -90.133910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100627585, states[0] = -41.016802, states[40]= 0.000258
Saving checkpoint... 
Iteration: 109097937, states[0] = -11.337904, states[40]= 0.002161
Saving checkpoint... 
Iteration: 118191904, states[0] = -77.420187, states[40]= 0.000001
Saving checkpoint... 
Iteration: 125610428, states[0] = -24.227010, states[40]= 0.000998
Saving checkpoint... 
Iteration: 133561736, states[0] = 12.491810, states[40]= 0.002829
Saving checkpoint... 
Iteration: 140829720, states[0] = -89.661543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148385223, states[0] = -90.005583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156328043, states[0] = -89.641233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166663498, states[0] = -66.939294, states[40]= 0.000004
Saving checkpoint... 
Iteration: 174839654, states[0] = -89.743079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183239755, states[0] = -86.217025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191753878, states[0] = -87.447534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199902456, states[0] = -90.058938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208470695, states[0] = -90.188598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217320105, states[0] = -89.548241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225346170, states[0] = -89.789372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234213980, states[0] = -82.470852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243352144, states[0] = -89.829763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251657718, states[0] = -63.924995, states[40]= 0.000006
Saving checkpoint... 
Iteration: 259745485, states[0] = -86.768487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268049252, states[0] = 17.815428, states[40]= 0.001898
Saving checkpoint... 
Iteration: 275904512, states[0] = -90.062906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282946500, states[0] = -90.155489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290796750, states[0] = -89.178368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299133384, states[0] = -46.190769, states[40]= 0.000126
Saving checkpoint... 
Iteration: 306890197, states[0] = -90.015489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316003924, states[0] = 33.704075, states[40]= 0.354349
Saving checkpoint... 
Iteration: 324382410, states[0] = -89.985317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331824301, states[0] = -89.593858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339741450, states[0] = -86.382402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348671225, states[0] = -70.371418, states[40]= 0.000002
Saving checkpoint... 
Iteration: 357529062, states[0] = 25.561382, states[40]= 0.000989
Saving checkpoint... 
Iteration: 366099228, states[0] = -12.557996, states[40]= 0.001946
Saving checkpoint... 
Iteration: 376720379, states[0] = -83.601317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385397612, states[0] = -90.040510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393019195, states[0] = 28.269515, states[40]= 0.002625
Saving checkpoint... 
Iteration: 401983834, states[0] = -90.197868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410260293, states[0] = -87.856582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418468867, states[0] = -90.183826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426839005, states[0] = -89.732012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434725994, states[0] = -84.479484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442516528, states[0] = 28.705943, states[40]= 0.005486
Saving checkpoint... 
Iteration: 450027661, states[0] = 26.021663, states[40]= 0.000988
Saving checkpoint... 
Iteration: 458183296, states[0] = -74.774719, states[40]= 0.000001
Saving checkpoint... 
Iteration: 466273994, states[0] = -88.519968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474437542, states[0] = -90.138969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483676324, states[0] = -72.358946, states[40]= 0.000001
Saving checkpoint... 
Iteration: 493155159, states[0] = -62.462034, states[40]= 0.000008
Saving checkpoint... 
Iteration: 501325815, states[0] = -89.608924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509785537, states[0] = -88.904947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519256810, states[0] = -87.639475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528231190, states[0] = -85.199300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537275487, states[0] = -88.576826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546427749, states[0] = -90.119373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555647348, states[0] = -57.435763, states[40]= 0.000021
Saving checkpoint... 
Iteration: 565371236, states[0] = -89.934200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573205231, states[0] = -80.674466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580818793, states[0] = -89.528607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588442584, states[0] = -90.147076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596762883, states[0] = -88.002039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604052058, states[0] = 16.661149, states[40]= 0.002093
Saving checkpoint... 
Iteration: 611723265, states[0] = -84.064109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619996168, states[0] = -90.205165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627772418, states[0] = -88.455340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636609424, states[0] = -23.135123, states[40]= 0.001022
Saving checkpoint... 
Iteration: 645246869, states[0] = -86.886644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654617602, states[0] = -31.293531, states[40]= 0.000734
Saving checkpoint... 
Iteration: 661637337, states[0] = -49.641161, states[40]= 0.000075
Saving checkpoint... 
Iteration: 670099991, states[0] = -13.345811, states[40]= 0.001816
Saving checkpoint... 
Iteration: 679134079, states[0] = -46.806978, states[40]= 0.000115
Saving checkpoint... 
Iteration: 686564698, states[0] = 11.167179, states[40]= 0.003061
Saving checkpoint... 
Iteration: 695367214, states[0] = -89.913418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704690754, states[0] = -77.035623, states[40]= 0.000001
Saving checkpoint... 
Iteration: 712982165, states[0] = -90.194644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721498935, states[0] = -90.206168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730370610, states[0] = -89.930157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739012683, states[0] = 29.029148, states[40]= 0.018721
Saving checkpoint... 
Iteration: 746303157, states[0] = -89.297587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755214044, states[0] = -82.476013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763530164, states[0] = 25.187899, states[40]= 0.001003
Saving checkpoint... 
Iteration: 771624260, states[0] = -37.730630, states[40]= 0.000390
Saving checkpoint... 
Iteration: 780176436, states[0] = -72.398488, states[40]= 0.000001
Saving checkpoint... 
Iteration: 788903472, states[0] = -90.056434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795893366, states[0] = -90.023681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804672147, states[0] = -70.743537, states[40]= 0.000002
Saving checkpoint... 
Iteration: 812405440, states[0] = -90.062125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820537627, states[0] = 22.447966, states[40]= 0.001248
Saving checkpoint... 
Iteration: 828735350, states[0] = -85.712724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836747128, states[0] = -86.907389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845065429, states[0] = 10.828298, states[40]= 0.003116
Saving checkpoint... 
Iteration: 853243226, states[0] = -86.552257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860943464, states[0] = -90.146906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869078011, states[0] = 4.342355, states[40]= 0.003881
Saving checkpoint... 
Iteration: 877552713, states[0] = 16.389594, states[40]= 0.002140
Saving checkpoint... 
Iteration: 885156737, states[0] = -63.369878, states[40]= 0.000007
Saving checkpoint... 
Iteration: 893687065, states[0] = -75.952749, states[40]= 0.000001
Saving checkpoint... 
Iteration: 901534543, states[0] = 23.615831, states[40]= 0.001124
Saving checkpoint... 
Iteration: 910346453, states[0] = -89.786040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918361650, states[0] = -89.882272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926616177, states[0] = -29.889813, states[40]= 0.000807
Saving checkpoint... 
Iteration: 934071104, states[0] = 8.073892, states[40]= 0.003521
Saving checkpoint... 
Iteration: 942111653, states[0] = -25.385877, states[40]= 0.000972
Saving checkpoint... 
Iteration: 951371419, states[0] = -89.932713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958589218, states[0] = -3.227004, states[40]= 0.003631
Saving checkpoint... 
Iteration: 966427043, states[0] = -90.115352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973994660, states[0] = -90.202124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982505174, states[0] = 31.227841, states[40]= 0.235535
Saving checkpoint... 
Iteration: 991501857, states[0] = 41.729856, states[40]= 0.506502
Saving checkpoint... 
Iteration: 999914685, states[0] = -90.086277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008050434, states[0] = 17.332391, states[40]= 0.001978
Saving checkpoint... 
Iteration: 1016466267, states[0] = -90.177387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023893341, states[0] = -90.022210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032171941, states[0] = -70.658952, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1040966194, states[0] = -90.177158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048910575, states[0] = -90.075158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056884001, states[0] = -89.987194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065412204, states[0] = -90.079426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073892794, states[0] = -90.019995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082019641, states[0] = 28.182158, states[40]= 0.002357
Saving checkpoint... 
Iteration: 1091407315, states[0] = -90.065845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098984659, states[0] = -90.194345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106523769, states[0] = 27.188162, states[40]= 0.001183
Saving checkpoint... 
Iteration: 1115208889, states[0] = -81.453627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124088723, states[0] = -2.833209, states[40]= 0.003681
Saving checkpoint... 
Iteration: 1132650290, states[0] = -59.431138, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1141382020, states[0] = -89.978665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149790790, states[0] = -89.038036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159947048, states[0] = -90.150871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167586797, states[0] = -1.365222, states[40]= 0.003831
Saving checkpoint... 
Iteration: 1175098232, states[0] = -11.531029, states[40]= 0.002127
Saving checkpoint... 
Iteration: 1183022221, states[0] = 27.595051, states[40]= 0.001431
Saving checkpoint... 
Iteration: 1191346302, states[0] = -89.783195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199573408, states[0] = 6.883587, states[40]= 0.003663
Saving checkpoint... 
Iteration: 1208053679, states[0] = 15.987136, states[40]= 0.002210
Saving checkpoint... 
Iteration: 1216487434, states[0] = -90.195754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225390801, states[0] = -90.011980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233742829, states[0] = -86.510647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242083307, states[0] = 1.072248, states[40]= 0.003954
Saving checkpoint... 
Iteration: 1250154018, states[0] = -61.778331, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1259433028, states[0] = -90.125773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268228657, states[0] = -84.852214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276802251, states[0] = -89.277824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285113351, states[0] = -27.083890, states[40]= 0.000924
Saving checkpoint... 
Iteration: 1293233129, states[0] = -85.439590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301874032, states[0] = -89.942879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311317039, states[0] = -89.501941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320457187, states[0] = -90.164486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329744733, states[0] = -86.689737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338440759, states[0] = -90.139473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346806725, states[0] = -89.353739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354974212, states[0] = -90.183671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364297052, states[0] = -89.176942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372648762, states[0] = -58.407990, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1381073166, states[0] = 7.011446, states[40]= 0.003649
Saving checkpoint... 
Iteration: 1389637813, states[0] = -50.040033, states[40]= 0.000071
Saving checkpoint... 
Iteration: 1398214105, states[0] = -82.482007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407139733, states[0] = -51.636448, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1415469791, states[0] = -90.178837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424446140, states[0] = -90.147857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432493267, states[0] = -90.198498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440762918, states[0] = -87.997163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449006651, states[0] = 29.850114, states[40]= 0.143297
Saving checkpoint... 
Iteration: 1457387960, states[0] = -90.000094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465972014, states[0] = -90.180831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474178866, states[0] = -73.270791, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1482262597, states[0] = -87.979224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491468012, states[0] = -90.176476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499959965, states[0] = -90.166990, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -90.077982
 - CaMKt in component CaMK (millimolar): 0.012518
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.701818
 - nass in component intracellular_ions (millimolar): 6.701910
 - ki in component intracellular_ions (millimolar): 145.176376
 - kss in component intracellular_ions (millimolar): 145.176357
 - cansr in component intracellular_ions (millimolar): 1.656532
 - cajsr in component intracellular_ions (millimolar): 1.613914
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.005885
 - hf in component INa (dimensionless): 0.768492
 - hs in component INa (dimensionless): 0.768451
 - j in component INa (dimensionless): 0.768145
 - hsp in component INa (dimensionless): 0.544951
 - jp in component INa (dimensionless): 0.767882
 - mL in component INaL (dimensionless): 0.000124
 - hL in component INaL (dimensionless): 0.549742
 - hLp in component INaL (dimensionless): 0.279247
 - a in component Ito (dimensionless): 0.000863
 - iF in component Ito (dimensionless): 0.999697
 - iS in component Ito (dimensionless): 0.569253
 - ap in component Ito (dimensionless): 0.000440
 - iFp in component Ito (dimensionless): 0.999697
 - iSp in component Ito (dimensionless): 0.620572
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.916472
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999838
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003042
 - xrf in component IKr (dimensionless): 0.000006
 - xrs in component IKr (dimensionless): 0.457674
 - xs1 in component IKs (dimensionless): 0.267679
 - xs2 in component IKs (dimensionless): 0.000151
 - xk1 in component IK1 (dimensionless): 0.998348
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:39:58 (23935): called boinc_finish(0)

</stderr_txt>
]]>