𝕏

Task 55298324

Name HuVeMOp_20240629112358674907_ORdGradInc_k_25-Drouin_EPI_1000-conf_215_1
Workunit 26258283
Created 29 Jun 2024, 9:27:31 UTC
Sent 29 Jun 2024, 15:49:45 UTC
Report deadline 2 Jul 2024, 15:49:45 UTC
Received 2 Jul 2024, 15:38:27 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 41 min 40 sec
CPU time 37 min 22 sec
Validate state Valid
Credit 45.84
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.66 MB
Peak swap size 391.76 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Drouin_EPI_1000-conf_215.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Drouin_EPI_1000-conf_215_1_r576291457_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Drouin_EPI_1000-conf_215_1_r576291457_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 90.753222
     * GNaL_b in INaL: 0.005640
     * Gto_b in Ito: 0.086885
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033429
     * GKs_b in IKs: 0.001978
     * GK1_b in IK1: 0.157008
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 67.865082
     * GKb_b in IKb: 0.003834
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020283
     * celltype in environment: 1.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9748087, states[0] = -94.331726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18905924, states[0] = -94.546002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29146702, states[0] = -63.114012, states[40]= 0.000048
Saving checkpoint... 
Iteration: 37842360, states[0] = -94.511104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46859562, states[0] = -94.545001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56124624, states[0] = -39.132915, states[40]= 0.001521
Saving checkpoint... 
Iteration: 65235334, states[0] = -94.269599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76259092, states[0] = -94.386629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86900236, states[0] = -94.621793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96998067, states[0] = -94.650628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106763432, states[0] = -94.420471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116409655, states[0] = -94.637964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126528719, states[0] = 23.200943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138108050, states[0] = -22.031357, states[40]= 0.002218
Saving checkpoint... 
Iteration: 149299642, states[0] = -94.524627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160582510, states[0] = 4.806558, states[40]= 0.000948
Saving checkpoint... 
Iteration: 170716851, states[0] = -94.195140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179920382, states[0] = -94.644400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189264431, states[0] = -94.428411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197778746, states[0] = -94.472231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209294760, states[0] = -94.511405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220069495, states[0] = 12.387130, states[40]= 0.000160
Saving checkpoint... 
Iteration: 228260094, states[0] = -94.410169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238204332, states[0] = -94.097120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245237700, states[0] = -94.312355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253707308, states[0] = -94.119466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262718584, states[0] = -94.199871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272481981, states[0] = -94.650366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281923090, states[0] = -94.637330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292212801, states[0] = -94.157163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301308086, states[0] = -94.530639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308901360, states[0] = -94.625990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318548712, states[0] = 20.426231, states[40]= 0.000004
Saving checkpoint... 
Iteration: 327598763, states[0] = -10.650840, states[40]= 0.002423
Saving checkpoint... 
Iteration: 335570816, states[0] = 11.718162, states[40]= 0.000196
Saving checkpoint... 
Iteration: 344161086, states[0] = -92.042607, states[40]= 0.000001
Saving checkpoint... 
Iteration: 355219514, states[0] = -94.197525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364957763, states[0] = -94.638752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375351211, states[0] = -94.583873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385255142, states[0] = -94.377375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393838117, states[0] = -94.567676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402024458, states[0] = 23.004221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413441709, states[0] = -94.631012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422658635, states[0] = -90.339539, states[40]= 0.000002
Saving checkpoint... 
Iteration: 432599936, states[0] = -12.091718, states[40]= 0.002330
Saving checkpoint... 
Iteration: 443056959, states[0] = 17.829439, states[40]= 0.000019
Saving checkpoint... 
Iteration: 454171313, states[0] = -93.686756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462219145, states[0] = -94.185300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472304737, states[0] = -94.508889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481757274, states[0] = -94.376863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489542481, states[0] = 21.854228, states[40]= 0.000001
Saving checkpoint... 
Iteration: 498941288, states[0] = -94.623287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509277234, states[0] = -94.440401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518300868, states[0] = -94.497030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528553740, states[0] = 18.941543, states[40]= 0.000010
Saving checkpoint... 
Iteration: 539515890, states[0] = 21.751369, states[40]= -0.000000
Saving checkpoint... 
Iteration: 550225711, states[0] = -94.218547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559858181, states[0] = -94.574071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568483036, states[0] = -94.624049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579141618, states[0] = -64.550791, states[40]= 0.000117
Saving checkpoint... 
Iteration: 589311992, states[0] = -94.511755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600486860, states[0] = -94.621550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609622976, states[0] = -40.636775, states[40]= 0.001891
Saving checkpoint... 
Iteration: 618497408, states[0] = -94.620695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628674064, states[0] = -93.737076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638353348, states[0] = -94.562473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649283977, states[0] = -94.446175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660102371, states[0] = -15.124977, states[40]= 0.002119
Saving checkpoint... 
Iteration: 670734664, states[0] = -94.258064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679555968, states[0] = 18.191850, states[40]= 0.000016
Saving checkpoint... 
Iteration: 689489555, states[0] = -94.613912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699013423, states[0] = 21.103107, states[40]= -0.000002
Saving checkpoint... 
Iteration: 708447331, states[0] = -94.606086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718104483, states[0] = -17.777783, states[40]= 0.002033
Saving checkpoint... 
Iteration: 729958236, states[0] = -94.606337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740595202, states[0] = -6.426361, states[40]= 0.002517
Saving checkpoint... 
Iteration: 751208277, states[0] = -94.081256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760023782, states[0] = 22.960653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769611522, states[0] = -26.471595, states[40]= 0.002732
Saving checkpoint... 
Iteration: 779773748, states[0] = -94.405797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786893516, states[0] = -94.579224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796841438, states[0] = -94.535550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806179064, states[0] = -93.796640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816524946, states[0] = 23.046863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826133440, states[0] = -54.013079, states[40]= 0.000478
Saving checkpoint... 
Iteration: 834527533, states[0] = 23.158264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844495968, states[0] = -94.600477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854651607, states[0] = -79.863084, states[40]= 0.000013
Saving checkpoint... 
Iteration: 863496875, states[0] = -94.598845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872677912, states[0] = -93.775340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882824325, states[0] = -94.505334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890734924, states[0] = -94.239355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898976021, states[0] = -94.593838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909970674, states[0] = -94.592175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920185476, states[0] = -93.859237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930718448, states[0] = -94.137784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940206773, states[0] = -94.052119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949970951, states[0] = -94.588651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960157109, states[0] = -88.594686, states[40]= 0.000003
Saving checkpoint... 
Iteration: 969005644, states[0] = 16.233581, states[40]= 0.000003
Saving checkpoint... 
Iteration: 978953957, states[0] = -94.583272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989313955, states[0] = -94.479269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998646032, states[0] = -70.698075, states[40]= 0.000048
Saving checkpoint... 
Iteration: 1007723242, states[0] = -94.161655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016365382, states[0] = -94.539526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024375713, states[0] = -94.546804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032818959, states[0] = -94.483623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044374385, states[0] = -94.544040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055751532, states[0] = -94.302087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065682984, states[0] = -93.818628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076848252, states[0] = -94.518019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085447927, states[0] = -94.572563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095626873, states[0] = -45.568283, states[40]= 0.001212
Saving checkpoint... 
Iteration: 1104420234, states[0] = -94.562964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114066732, states[0] = 13.756938, states[40]= 0.000101
Saving checkpoint... 
Iteration: 1124452447, states[0] = -94.570075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134787472, states[0] = -94.411386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144332100, states[0] = -94.492816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154127466, states[0] = -46.324101, states[40]= 0.001123
Saving checkpoint... 
Iteration: 1163451795, states[0] = -94.566437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172590306, states[0] = -1.406378, states[40]= 0.002023
Saving checkpoint... 
Iteration: 1181371088, states[0] = -94.529352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191970805, states[0] = -94.567088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200858707, states[0] = -94.517240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209045095, states[0] = 21.338728, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1219541771, states[0] = 22.007202, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1231047691, states[0] = 20.721091, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1241230827, states[0] = -94.185198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251074215, states[0] = 9.942752, states[40]= 0.000314
Saving checkpoint... 
Iteration: 1260889466, states[0] = -94.534584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269753008, states[0] = -94.288739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279882409, states[0] = -94.528539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290878550, states[0] = -94.524969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301512107, states[0] = 20.689802, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1310270200, states[0] = -94.346934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320565468, states[0] = 14.355365, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1328817385, states[0] = -94.454516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338174566, states[0] = -93.679349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345819157, states[0] = -94.455858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354352550, states[0] = -94.497601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365017369, states[0] = 22.084761, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1375892596, states[0] = -94.526103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386427883, states[0] = -94.540321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395682986, states[0] = -93.787942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406183327, states[0] = -93.790764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415965679, states[0] = -94.546354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425395610, states[0] = -94.523315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434168347, states[0] = -93.453406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444130569, states[0] = -50.283991, states[40]= 0.000735
Saving checkpoint... 
Iteration: 1454949579, states[0] = -94.539938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464014326, states[0] = 21.374175, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1472979638, states[0] = -94.543088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482061836, states[0] = 15.959269, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1490781121, states[0] = -94.362744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499855681, states[0] = -94.487634, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.418157
 - CaMKt in component CaMK (millimolar): 0.029380
 - cass in component intracellular_ions (millimolar): 0.000110
 - nai in component intracellular_ions (millimolar): 7.990323
 - nass in component intracellular_ions (millimolar): 7.990504
 - ki in component intracellular_ions (millimolar): 142.884353
 - kss in component intracellular_ions (millimolar): 142.884314
 - cansr in component intracellular_ions (millimolar): 3.385062
 - cajsr in component intracellular_ions (millimolar): 3.366355
 - cai in component intracellular_ions (millimolar): 0.000115
 - m in component INa (dimensionless): 0.003800
 - hf in component INa (dimensionless): 0.871351
 - hs in component INa (dimensionless): 0.871349
 - j in component INa (dimensionless): 0.871326
 - hsp in component INa (dimensionless): 0.709746
 - jp in component INa (dimensionless): 0.871305
 - mL in component INaL (dimensionless): 0.000054
 - hL in component INaL (dimensionless): 0.697120
 - hLp in component INaL (dimensionless): 0.438071
 - a in component Ito (dimensionless): 0.000644
 - iF in component Ito (dimensionless): 0.999858
 - iS in component Ito (dimensionless): 0.999858
 - ap in component Ito (dimensionless): 0.000328
 - iFp in component Ito (dimensionless): 0.999858
 - iSp in component Ito (dimensionless): 0.999858
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.918704
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999872
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.007364
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.321160
 - xs1 in component IKs (dimensionless): 0.269156
 - xs2 in component IKs (dimensionless): 0.000093
 - xk1 in component IK1 (dimensionless): 0.997461
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:38:17 (8661): called boinc_finish(0)

</stderr_txt>
]]>


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