𝕏

Task 55298073

Name HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_14_0
Workunit 26258158
Created 29 Jun 2024, 9:27:25 UTC
Sent 29 Jun 2024, 15:45:11 UTC
Report deadline 3 Jul 2024, 1:21:11 UTC
Received 30 Jun 2024, 5:12:49 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218427
Run time 2 hours 39 min 58 sec
CPU time 2 hours 33 min 58 sec
Validate state Valid
Credit 60.69
Device peak FLOPS 4.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.02 MB
Peak swap size 32.57 GB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.16.19</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_14.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_14_0_r568291732_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Pueyo_APDR-conf_14_0_r568291732_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 111.727334
     * GNaL_b in INaL: 0.006681
     * Gto_b in Ito: 0.089601
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033751
     * GKs_b in IKs: 0.001877
     * GK1_b in IK1: 0.159851
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 65.826329
     * GKb_b in IKb: 0.003905
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.039554
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12875159, states[0] = -95.077215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25076779, states[0] = -2.186157, states[40]= 0.003931
Saving checkpoint... 
Iteration: 38656324, states[0] = -89.447155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52338434, states[0] = -95.020523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66019165, states[0] = 20.882016, states[40]= 0.010259
Saving checkpoint... 
Iteration: 79664448, states[0] = -94.011405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93282533, states[0] = -94.971300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106933942, states[0] = -95.041816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120533966, states[0] = 17.116337, states[40]= 0.005537
Saving checkpoint... 
Iteration: 134233253, states[0] = -94.909491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147894000, states[0] = -95.029522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161164385, states[0] = -93.889137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174855854, states[0] = -95.014867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188340548, states[0] = -95.007423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202012469, states[0] = 22.018794, states[40]= 0.030403
Saving checkpoint... 
Iteration: 215599876, states[0] = -20.556527, states[40]= 0.000928
Saving checkpoint... 
Iteration: 229285222, states[0] = -94.969386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242817152, states[0] = -94.993667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256504053, states[0] = 31.088157, states[40]= 0.160517
Saving checkpoint... 
Iteration: 270221652, states[0] = -94.889442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283879895, states[0] = -95.023918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297576948, states[0] = -1.303505, states[40]= 0.004064
Saving checkpoint... 
Iteration: 311271013, states[0] = -94.955622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324961942, states[0] = -95.044006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338657264, states[0] = -88.730411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352372529, states[0] = -95.021170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366053706, states[0] = 9.876212, states[40]= 0.004884
Saving checkpoint... 
Iteration: 379742070, states[0] = -94.920797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393438738, states[0] = -95.039733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407143537, states[0] = -67.214783, states[40]= 0.000002
Saving checkpoint... 
Iteration: 420820296, states[0] = -94.995490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434509862, states[0] = 22.614074, states[40]= 0.055458
Saving checkpoint... 
Iteration: 448006245, states[0] = 25.287280, states[40]= 0.126522
Saving checkpoint... 
Iteration: 461323692, states[0] = -94.997555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475022153, states[0] = 20.375732, states[40]= 0.008052
Saving checkpoint... 
Iteration: 488426010, states[0] = -95.036930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502095979, states[0] = -16.807749, states[40]= 0.001245
Saving checkpoint... 
Iteration: 515769137, states[0] = -94.953523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529311618, states[0] = -94.989740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542830500, states[0] = -95.001488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556413857, states[0] = -95.033947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570154437, states[0] = -84.414735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583795736, states[0] = -94.977948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597428332, states[0] = -95.037381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611152742, states[0] = -81.504108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624792789, states[0] = -94.975524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638411000, states[0] = -95.033151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652072773, states[0] = 1.113315, states[40]= 0.004382
Saving checkpoint... 
Iteration: 665362860, states[0] = -95.017132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678393000, states[0] = -95.027973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691703535, states[0] = -94.855768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706209961, states[0] = -94.868176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720100612, states[0] = -21.256729, states[40]= 0.000886
Saving checkpoint... 
Iteration: 734022453, states[0] = 20.310907, states[40]= 0.007901
Saving checkpoint... 
Iteration: 747980445, states[0] = -95.046479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761833135, states[0] = -95.002814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775799785, states[0] = -94.980996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789688699, states[0] = -94.824511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803635180, states[0] = -56.931659, states[40]= 0.000009
Saving checkpoint... 
Iteration: 817531064, states[0] = 18.049572, states[40]= 0.005823
Saving checkpoint... 
Iteration: 831434241, states[0] = -95.038506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845331537, states[0] = -95.001868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859199450, states[0] = -94.847443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873162310, states[0] = -93.124569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887043884, states[0] = 13.668773, states[40]= 0.005044
Saving checkpoint... 
Iteration: 900983462, states[0] = -95.046782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914942078, states[0] = -95.040046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928948089, states[0] = -95.041184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942742724, states[0] = -94.921319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956580800, states[0] = -3.819256, states[40]= 0.003631
Saving checkpoint... 
Iteration: 970497796, states[0] = -95.048511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984405412, states[0] = -95.031411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998375405, states[0] = -95.021803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012238152, states[0] = -94.914815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026147587, states[0] = -72.982711, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1040043462, states[0] = 13.825114, states[40]= 0.005055
Saving checkpoint... 
Iteration: 1053912500, states[0] = -95.033262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067774388, states[0] = -94.958522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081632198, states[0] = -53.498217, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1095617875, states[0] = -38.044596, states[40]= 0.000172
Saving checkpoint... 
Iteration: 1109464054, states[0] = -95.043812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123404106, states[0] = -95.030953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137323836, states[0] = -94.997185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151188280, states[0] = -94.823298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165118548, states[0] = -38.724405, states[40]= 0.000156
Saving checkpoint... 
Iteration: 1179002222, states[0] = 43.078135, states[40]= 0.102728
Saving checkpoint... 
Iteration: 1192935333, states[0] = -95.038492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206794704, states[0] = -94.976695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220733998, states[0] = -94.908543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234585266, states[0] = -7.163442, states[40]= 0.002942
Saving checkpoint... 
Iteration: 1248352687, states[0] = -95.012313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262233376, states[0] = -94.907575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276175148, states[0] = -94.762436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289766414, states[0] = -94.950095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303689800, states[0] = -94.826656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317482388, states[0] = -95.046358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331229505, states[0] = -94.901546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344990609, states[0] = -95.047399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358875791, states[0] = -95.021701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372757963, states[0] = -94.940492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386656073, states[0] = -87.037274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400605947, states[0] = -26.382830, states[40]= 0.000635
Saving checkpoint... 
Iteration: 1414508025, states[0] = 23.475620, states[40]= 0.085954
Saving checkpoint... 
Iteration: 1428459360, states[0] = -95.042831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442358943, states[0] = -95.014954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455848789, states[0] = -95.010359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468966461, states[0] = -95.043950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482454722, states[0] = -95.042004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496376350, states[0] = -95.021812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510206066, states[0] = 27.084549, states[40]= 0.113101
Saving checkpoint... 
Iteration: 1523939220, states[0] = -95.248109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537688134, states[0] = -95.177168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551676278, states[0] = -12.764041, states[40]= 0.002056
Saving checkpoint... 
Iteration: 1565388757, states[0] = -95.321632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579127658, states[0] = -95.264121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592928420, states[0] = -95.267580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606655456, states[0] = -95.108114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620437565, states[0] = -92.491243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1634229821, states[0] = -81.526051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1648051450, states[0] = -95.075189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1661814957, states[0] = -58.495748, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1675540661, states[0] = 11.847696, states[40]= 0.005975
Saving checkpoint... 
Iteration: 1689290134, states[0] = -95.332683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703068609, states[0] = -95.315929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1716771856, states[0] = -95.164327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1730453590, states[0] = 4.928415, states[40]= 0.005371
Saving checkpoint... 
Iteration: 1744026523, states[0] = -75.643284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1757427885, states[0] = 17.576273, states[40]= 0.007330
Saving checkpoint... 
Iteration: 1771234150, states[0] = 14.918351, states[40]= 0.006458
Saving checkpoint... 
Iteration: 1784976130, states[0] = -95.322290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1798770757, states[0] = -95.317818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1812510508, states[0] = 22.119892, states[40]= 0.047237
Saving checkpoint... 
Iteration: 1826277014, states[0] = -94.996187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839978268, states[0] = -95.069458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1853692869, states[0] = -94.849314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867405802, states[0] = -95.041654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1881135819, states[0] = -58.229770, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1894885271, states[0] = -95.029438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1908614902, states[0] = -35.276308, states[40]= 0.000251
Saving checkpoint... 
Iteration: 1922380035, states[0] = -95.024958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936070857, states[0] = 2.099229, states[40]= 0.004485
Saving checkpoint... 
Iteration: 1949817254, states[0] = -94.993445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963506869, states[0] = 24.476738, states[40]= 0.111498
Saving checkpoint... 
Iteration: 1977298049, states[0] = -94.979218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991053942, states[0] = 9.776124, states[40]= 0.004882
Saving checkpoint... 
Iteration: 2004800481, states[0] = -94.980833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2018573159, states[0] = 0.897955, states[40]= 0.004358
Saving checkpoint... 
Iteration: 2032028647, states[0] = 18.754958, states[40]= 0.006154
Saving checkpoint... 
Iteration: 2045727527, states[0] = -94.897911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2059507854, states[0] = 23.593733, states[40]= 0.089444
Saving checkpoint... 
Iteration: 2072977888, states[0] = -95.045194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086717097, states[0] = -94.880231, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.923824
 - CaMKt in component CaMK (millimolar): 0.007091
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.728379
 - nass in component intracellular_ions (millimolar): 6.728440
 - ki in component intracellular_ions (millimolar): 145.246990
 - kss in component intracellular_ions (millimolar): 145.246969
 - cansr in component intracellular_ions (millimolar): 1.320277
 - cajsr in component intracellular_ions (millimolar): 1.282382
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003610
 - hf in component INa (dimensionless): 0.880382
 - hs in component INa (dimensionless): 0.880377
 - j in component INa (dimensionless): 0.880349
 - hsp in component INa (dimensionless): 0.726549
 - jp in component INa (dimensionless): 0.880330
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711063
 - hLp in component INaL (dimensionless): 0.454351
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.623606
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.699042
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936874
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999891
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001628
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.328036
 - xs1 in component IKs (dimensionless): 0.238717
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997331
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:12:32 (42867): called boinc_finish(0)

</stderr_txt>
]]>


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