𝕏

Task 55293800

Name HuVeMOp_20240629112358674907_ORdGradInc_k_25-Coppini_2000-conf_106_1
Workunit 26256022
Created 29 Jun 2024, 9:25:25 UTC
Sent 29 Jun 2024, 15:15:20 UTC
Report deadline 2 Jul 2024, 15:15:20 UTC
Received 30 Jun 2024, 0:06:17 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 40 min 13 sec
CPU time 1 hours 36 min 8 sec
Validate state Valid
Credit 42.66
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.06 MB
Peak swap size 4.13 GB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Coppini_2000-conf_106.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Coppini_2000-conf_106_1_r1321346054_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Coppini_2000-conf_106_1_r1321346054_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 114.881746
     * GNaL_b in INaL: 0.005722
     * Gto_b in Ito: 0.094237
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033257
     * GKs_b in IKs: 0.001757
     * GK1_b in IK1: 0.179130
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 70.431105
     * GKb_b in IKb: 0.003757
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050531
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11432014, states[0] = -94.763776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23456061, states[0] = -94.721808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35764578, states[0] = -94.732449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50440592, states[0] = -94.679898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64447722, states[0] = -94.676255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75921480, states[0] = -94.708074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87834485, states[0] = -94.707164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98578440, states[0] = -94.698245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109611225, states[0] = -94.700142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120449434, states[0] = -94.667687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131190412, states[0] = -94.008421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142321515, states[0] = -94.571074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152878897, states[0] = -94.701485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164106992, states[0] = -10.658247, states[40]= 0.002365
Saving checkpoint... 
Iteration: 175287974, states[0] = -94.518011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186104668, states[0] = -8.609926, states[40]= 0.002799
Saving checkpoint... 
Iteration: 198618652, states[0] = -94.697618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210639849, states[0] = -94.698846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220879804, states[0] = -94.700516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233212376, states[0] = -94.311829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245818093, states[0] = -94.701270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258700326, states[0] = -94.700844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270291564, states[0] = -94.523821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281260556, states[0] = -94.459055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292243574, states[0] = -94.413979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303463704, states[0] = -94.670117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316149309, states[0] = -49.521379, states[40]= 0.000097
Saving checkpoint... 
Iteration: 328979617, states[0] = -94.698101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340100510, states[0] = -5.190410, states[40]= 0.003529
Saving checkpoint... 
Iteration: 352256288, states[0] = -94.448272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363718110, states[0] = -94.700919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375645414, states[0] = -94.698632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386842340, states[0] = -94.700640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398595429, states[0] = -94.695079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410651842, states[0] = -94.698880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423312858, states[0] = -94.557415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435463337, states[0] = -94.669731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446983161, states[0] = -94.697790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458824007, states[0] = -94.700730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471959472, states[0] = -94.698279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482769663, states[0] = -94.701026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494958582, states[0] = -94.698256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507705903, states[0] = -94.700438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521102229, states[0] = -6.554365, states[40]= 0.003246
Saving checkpoint... 
Iteration: 533715704, states[0] = -94.700560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544672944, states[0] = -94.699487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557234710, states[0] = -94.386895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568991686, states[0] = -94.697365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579993163, states[0] = -94.697310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591962681, states[0] = -94.697982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604635000, states[0] = -94.697631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617745482, states[0] = -94.700714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630644903, states[0] = -94.698126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642433627, states[0] = -94.657826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655066879, states[0] = 12.979106, states[40]= 0.003693
Saving checkpoint... 
Iteration: 667495256, states[0] = -94.678578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680066152, states[0] = 13.267112, states[40]= 0.003648
Saving checkpoint... 
Iteration: 692857356, states[0] = -94.699847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705795781, states[0] = -94.700514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718114462, states[0] = -17.430257, states[40]= 0.001398
Saving checkpoint... 
Iteration: 730430096, states[0] = -94.656067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742646050, states[0] = -94.697974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755168913, states[0] = -71.395409, states[40]= 0.000003
Saving checkpoint... 
Iteration: 768082367, states[0] = 6.048048, states[40]= 0.004408
Saving checkpoint... 
Iteration: 780729956, states[0] = -94.700283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793049000, states[0] = 19.317274, states[40]= 0.002507
Saving checkpoint... 
Iteration: 805860744, states[0] = -94.699583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818635715, states[0] = -94.697272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830786503, states[0] = -94.700330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843226740, states[0] = -94.360686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855871684, states[0] = -94.699311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867941696, states[0] = -94.697926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880712127, states[0] = -94.699852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892236005, states[0] = -94.390270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905191359, states[0] = -94.059240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916892804, states[0] = -94.698822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929955142, states[0] = -94.697516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942851413, states[0] = -94.699468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956122150, states[0] = -24.367548, states[40]= 0.001254
Saving checkpoint... 
Iteration: 968858712, states[0] = -94.699309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981486370, states[0] = -94.675676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994652428, states[0] = -94.697812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007256917, states[0] = -94.448618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019904506, states[0] = -94.698406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032298309, states[0] = -94.533894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044675488, states[0] = -94.698636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057166629, states[0] = -68.322322, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1069430843, states[0] = -94.655772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082469923, states[0] = -94.670664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095278338, states[0] = -94.497101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108443261, states[0] = -94.661040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122182862, states[0] = -91.725470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135397362, states[0] = -94.637726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147782920, states[0] = -94.699750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160439219, states[0] = -94.659271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172971480, states[0] = -94.696695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186281202, states[0] = -94.502662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198814024, states[0] = -94.699445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211522867, states[0] = -94.683618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224394093, states[0] = -94.635486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236504329, states[0] = -94.679679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248445566, states[0] = -94.661702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261670440, states[0] = -94.698054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274014581, states[0] = 25.910559, states[40]= 0.011516
Saving checkpoint... 
Iteration: 1287880593, states[0] = -94.698348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300600605, states[0] = -94.693850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313570480, states[0] = -94.690731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326507825, states[0] = -94.680298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338335141, states[0] = -94.584164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351597335, states[0] = -94.693464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364606213, states[0] = -94.694203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377039320, states[0] = 22.181006, states[40]= 0.001970
Saving checkpoint... 
Iteration: 1390005853, states[0] = 26.815708, states[40]= 0.197543
Saving checkpoint... 
Iteration: 1402649123, states[0] = -94.696890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415281325, states[0] = -94.502471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428560954, states[0] = -94.689317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441202446, states[0] = -94.268721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452673026, states[0] = -94.697787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465072508, states[0] = 10.647260, states[40]= 0.004019
Saving checkpoint... 
Iteration: 1476142305, states[0] = -42.668159, states[40]= 0.000261
Saving checkpoint... 
Iteration: 1488642142, states[0] = -94.696372, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.571363
 - CaMKt in component CaMK (millimolar): 0.004230
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.567115
 - nass in component intracellular_ions (millimolar): 6.567200
 - ki in component intracellular_ions (millimolar): 145.343216
 - kss in component intracellular_ions (millimolar): 145.343200
 - cansr in component intracellular_ions (millimolar): 1.597962
 - cajsr in component intracellular_ions (millimolar): 1.597360
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.003741
 - hf in component INa (dimensionless): 0.874146
 - hs in component INa (dimensionless): 0.874147
 - j in component INa (dimensionless): 0.874152
 - hsp in component INa (dimensionless): 0.714924
 - jp in component INa (dimensionless): 0.874155
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.720230
 - hLp in component INaL (dimensionless): 0.513261
 - a in component Ito (dimensionless): 0.000638
 - iF in component Ito (dimensionless): 0.999862
 - iS in component Ito (dimensionless): 0.893677
 - ap in component Ito (dimensionless): 0.000325
 - iFp in component Ito (dimensionless): 0.999862
 - iSp in component Ito (dimensionless): 0.933373
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.976610
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002754
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.094621
 - xs1 in component IKs (dimensionless): 0.121991
 - xs2 in component IKs (dimensionless): 0.000091
 - xk1 in component IK1 (dimensionless): 0.997422
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:27:48 (89209): called boinc_finish(0)

</stderr_txt>
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