𝕏

Task 55292395

Name HuVeMOp_20240629112358674907_ORdGradInc_k_25-Drouin_EPI_3000-conf_102_0
Workunit 26255321
Created 29 Jun 2024, 9:24:43 UTC
Sent 29 Jun 2024, 15:02:15 UTC
Report deadline 2 Jul 2024, 15:02:15 UTC
Received 30 Jun 2024, 4:53:41 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 208022
Run time 3 hours 32 min 24 sec
CPU time 3 hours 19 min 29 sec
Validate state Valid
Credit 43.27
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.47 MB
Peak swap size 3.68 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.17</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Drouin_EPI_3000-conf_102.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Drouin_EPI_3000-conf_102_0_r466231630_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Drouin_EPI_3000-conf_102_0_r466231630_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.557514
     * GNaL_b in INaL: 0.005493
     * Gto_b in Ito: 0.090682
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034031
     * GKs_b in IKs: 0.002049
     * GK1_b in IK1: 0.165937
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 74.687179
     * GKb_b in IKb: 0.003922
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018681
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7357920, states[0] = -94.343696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14723048, states[0] = -94.285672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22103805, states[0] = -94.257693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29418223, states[0] = -94.248350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36787548, states[0] = -94.246478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44209047, states[0] = -94.246903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51568492, states[0] = -94.244499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58931689, states[0] = -94.207796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66267719, states[0] = -93.920949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73654692, states[0] = -58.223327, states[40]= 0.000031
Saving checkpoint... 
Iteration: 81032955, states[0] = 25.446260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88378796, states[0] = -94.230368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95741703, states[0] = -94.237405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103112850, states[0] = -94.244586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110500668, states[0] = -94.251364, states[40]= 0.000000
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Iteration: 117881289, states[0] = -94.258634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125238642, states[0] = -94.266097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132647388, states[0] = -94.268322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139820024, states[0] = -94.092888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147196751, states[0] = -93.491562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154591426, states[0] = 6.709854, states[40]= 0.000071
Saving checkpoint... 
Iteration: 161843459, states[0] = -94.240558, states[40]= 0.000000
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Iteration: 168856929, states[0] = -94.262986, states[40]= 0.000000
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Iteration: 175792690, states[0] = -94.024834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182735669, states[0] = -94.244945, states[40]= 0.000000
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Iteration: 189718225, states[0] = -94.269131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196614307, states[0] = -12.169578, states[40]= 0.000262
Saving checkpoint... 
Iteration: 203527752, states[0] = -94.254302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210519779, states[0] = -94.259271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217621820, states[0] = -20.653507, states[40]= 0.000263
Saving checkpoint... 
Iteration: 224706738, states[0] = -94.245903, states[40]= 0.000000
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Iteration: 231747681, states[0] = -94.267821, states[40]= 0.000000
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Iteration: 238799028, states[0] = -94.042616, states[40]= 0.000000
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Iteration: 245701963, states[0] = -94.245820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252791458, states[0] = -94.265695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259859899, states[0] = -94.161344, states[40]= 0.000000
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Iteration: 266802674, states[0] = -94.241483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273893338, states[0] = -94.260275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280949678, states[0] = -94.235818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287996174, states[0] = -94.234603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295026314, states[0] = -94.253069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302028361, states[0] = -94.259508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309125604, states[0] = -24.924585, states[40]= 0.000331
Saving checkpoint... 
Iteration: 316007555, states[0] = -94.253631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322987993, states[0] = -94.249675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329992613, states[0] = -94.233955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337002117, states[0] = -94.253522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343874464, states[0] = -94.177783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350656865, states[0] = -94.245926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357492638, states[0] = -94.250392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364370059, states[0] = -94.237296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370761936, states[0] = -93.910994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377538597, states[0] = -94.250950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384441115, states[0] = -94.229656, states[40]= 0.000000
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Iteration: 391368204, states[0] = -94.236860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398291926, states[0] = -94.263067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405068513, states[0] = 18.052527, states[40]= 0.000004
Saving checkpoint... 
Iteration: 412081252, states[0] = -94.248247, states[40]= 0.000000
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Iteration: 418126484, states[0] = -94.246034, states[40]= 0.000000
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Iteration: 423166098, states[0] = -74.908852, states[40]= 0.000003
Saving checkpoint... 
Iteration: 426835164, states[0] = -94.260469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430515047, states[0] = 22.240564, states[40]= 0.000000
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Iteration: 434246223, states[0] = -94.264304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438005302, states[0] = 14.707487, states[40]= 0.000022
Saving checkpoint... 
Iteration: 441697602, states[0] = -94.265603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445436604, states[0] = -94.233569, states[40]= 0.000000
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Iteration: 449205834, states[0] = -94.265280, states[40]= 0.000000
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Iteration: 452678715, states[0] = -94.243088, states[40]= 0.000000
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Iteration: 457307527, states[0] = -94.237830, states[40]= 0.000000
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Iteration: 463865758, states[0] = -94.165199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470904324, states[0] = -94.234152, states[40]= 0.000000
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Iteration: 478291761, states[0] = -94.238032, states[40]= 0.000000
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Iteration: 485675734, states[0] = -94.242601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493054332, states[0] = -94.248040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500410019, states[0] = -94.255254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507789910, states[0] = -94.261132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515210955, states[0] = -94.263924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522553936, states[0] = -94.259238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529783289, states[0] = -93.989511, states[40]= 0.000000
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Iteration: 537184884, states[0] = -93.188356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544594377, states[0] = 4.835242, states[40]= 0.000097
Saving checkpoint... 
Iteration: 551950712, states[0] = -94.231138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559360763, states[0] = -94.234005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566773879, states[0] = -94.237076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574123073, states[0] = -94.243299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581482775, states[0] = -94.249976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588873887, states[0] = -94.255496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596294557, states[0] = -94.259281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603652067, states[0] = -94.263012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611047759, states[0] = -94.256807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618426840, states[0] = -94.217173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625840481, states[0] = -94.125440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633158845, states[0] = -64.718613, states[40]= 0.000014
Saving checkpoint... 
Iteration: 640564001, states[0] = 19.759077, states[40]= 0.000002
Saving checkpoint... 
Iteration: 647955977, states[0] = -94.229188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655312376, states[0] = -94.233971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662680208, states[0] = -94.239123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670063965, states[0] = -94.244292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677450281, states[0] = -94.249872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684846741, states[0] = -94.255107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692257471, states[0] = -94.259094, states[40]= 0.000000
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Iteration: 699634005, states[0] = -94.261031, states[40]= 0.000000
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Iteration: 707020588, states[0] = -94.250569, states[40]= 0.000000
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Iteration: 714420745, states[0] = -94.211482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721843553, states[0] = -94.128719, states[40]= 0.000000
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Iteration: 729261713, states[0] = -93.903241, states[40]= 0.000000
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Iteration: 736635532, states[0] = -36.326005, states[40]= 0.000313
Saving checkpoint... 
Iteration: 743999436, states[0] = -94.226067, states[40]= 0.000000
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Iteration: 751426887, states[0] = -94.228199, states[40]= 0.000000
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Iteration: 758857681, states[0] = -94.230409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766230930, states[0] = -94.235080, states[40]= 0.000000
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Iteration: 773624625, states[0] = -94.239525, states[40]= 0.000000
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Iteration: 781041776, states[0] = -94.243313, states[40]= 0.000000
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Iteration: 788460190, states[0] = -94.247300, states[40]= 0.000000
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Iteration: 795861366, states[0] = -94.252304, states[40]= 0.000000
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Iteration: 803269157, states[0] = -94.256565, states[40]= 0.000000
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Iteration: 810668598, states[0] = -94.259170, states[40]= 0.000000
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Iteration: 818079245, states[0] = -94.256304, states[40]= 0.000000
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Iteration: 825503177, states[0] = -94.244518, states[40]= 0.000000
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Iteration: 832921866, states[0] = -94.210022, states[40]= 0.000000
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Iteration: 840345067, states[0] = -94.128935, states[40]= 0.000000
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Iteration: 847761816, states[0] = -93.901451, states[40]= 0.000000
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Iteration: 855150626, states[0] = -54.714595, states[40]= 0.000052
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Iteration: 862585899, states[0] = 9.835228, states[40]= 0.000038
Saving checkpoint... 
Iteration: 869983658, states[0] = -94.224203, states[40]= 0.000000
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Iteration: 877369104, states[0] = -94.227806, states[40]= 0.000000
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Iteration: 884771657, states[0] = -94.231258, states[40]= 0.000000
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Iteration: 892189039, states[0] = -94.234487, states[40]= 0.000000
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Iteration: 899589808, states[0] = -94.238804, states[40]= 0.000000
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Iteration: 907030076, states[0] = -94.241561, states[40]= 0.000000
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Iteration: 914441661, states[0] = -94.245938, states[40]= 0.000000
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Iteration: 921873072, states[0] = -94.249377, states[40]= 0.000000
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Iteration: 929290841, states[0] = -94.253292, states[40]= 0.000000
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Iteration: 936758305, states[0] = -94.254544, states[40]= 0.000000
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Iteration: 944170110, states[0] = -94.256696, states[40]= 0.000000
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Iteration: 951569456, states[0] = -94.252987, states[40]= 0.000000
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Iteration: 958994208, states[0] = -94.239704, states[40]= 0.000000
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Iteration: 966368555, states[0] = -94.159296, states[40]= 0.000000
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Iteration: 973602544, states[0] = -0.928609, states[40]= 0.000200
Saving checkpoint... 
Iteration: 981024984, states[0] = 24.585768, states[40]= 0.000000
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Iteration: 988381738, states[0] = -94.225321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994448459, states[0] = -94.223001, states[40]= 0.000000
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Iteration: 1001362317, states[0] = -94.248459, states[40]= 0.000000
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Iteration: 1008230299, states[0] = -93.731458, states[40]= 0.000000
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Iteration: 1015318343, states[0] = -94.227077, states[40]= 0.000000
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Iteration: 1022312359, states[0] = -94.250566, states[40]= 0.000000
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Iteration: 1029357014, states[0] = -94.143166, states[40]= 0.000000
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Iteration: 1036358303, states[0] = -94.225251, states[40]= 0.000000
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Iteration: 1043383890, states[0] = -94.246570, states[40]= 0.000000
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Iteration: 1050398015, states[0] = -94.187990, states[40]= 0.000000
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Iteration: 1057446862, states[0] = -94.221884, states[40]= 0.000000
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Iteration: 1064494762, states[0] = -94.240422, states[40]= 0.000000
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Iteration: 1071528429, states[0] = -94.245295, states[40]= 0.000000
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Iteration: 1078129699, states[0] = -94.233659, states[40]= 0.000000
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Iteration: 1085205781, states[0] = -94.253510, states[40]= 0.000000
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Iteration: 1092069724, states[0] = 17.568674, states[40]= 0.000005
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Iteration: 1099182877, states[0] = -94.230921, states[40]= 0.000000
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Iteration: 1106242165, states[0] = -94.252015, states[40]= 0.000000
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Iteration: 1113356789, states[0] = -94.141287, states[40]= 0.000000
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Iteration: 1120697774, states[0] = -93.484725, states[40]= 0.000000
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Iteration: 1128092503, states[0] = 6.016093, states[40]= 0.000080
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Iteration: 1135496932, states[0] = -94.218885, states[40]= 0.000000
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Iteration: 1142908281, states[0] = -94.221556, states[40]= 0.000000
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Iteration: 1150334569, states[0] = -94.223980, states[40]= 0.000000
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Iteration: 1157757737, states[0] = -94.226751, states[40]= 0.000000
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Iteration: 1165146074, states[0] = -94.231308, states[40]= 0.000000
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Iteration: 1172565593, states[0] = -94.234905, states[40]= 0.000000
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Iteration: 1179926440, states[0] = -94.241812, states[40]= 0.000000
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Iteration: 1187361240, states[0] = -94.245068, states[40]= 0.000000
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Iteration: 1194766700, states[0] = -94.249424, states[40]= 0.000000
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Iteration: 1202117062, states[0] = -94.251299, states[40]= 0.000000
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Iteration: 1209503998, states[0] = -94.237615, states[40]= 0.000000
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Iteration: 1216942565, states[0] = -94.214984, states[40]= 0.000000
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Iteration: 1224363678, states[0] = -94.148417, states[40]= 0.000000
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Iteration: 1231787145, states[0] = -93.988891, states[40]= 0.000000
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Iteration: 1239214135, states[0] = -93.615251, states[40]= 0.000000
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Iteration: 1246619615, states[0] = -18.151078, states[40]= 0.000245
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Iteration: 1254021178, states[0] = 23.885458, states[40]= 0.000000
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Iteration: 1261421295, states[0] = -94.218922, states[40]= 0.000000
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Iteration: 1268832836, states[0] = -94.221841, states[40]= 0.000000
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Iteration: 1276251457, states[0] = -94.224799, states[40]= 0.000000
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Iteration: 1283664303, states[0] = -94.228302, states[40]= 0.000000
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Iteration: 1291011407, states[0] = -94.235377, states[40]= 0.000000
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Iteration: 1298432940, states[0] = -94.239277, states[40]= 0.000000
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Iteration: 1305834065, states[0] = -94.244254, states[40]= 0.000000
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Iteration: 1313249877, states[0] = -94.247902, states[40]= 0.000000
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Iteration: 1320656976, states[0] = -94.249766, states[40]= 0.000000
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Iteration: 1328074356, states[0] = -94.246460, states[40]= 0.000000
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Iteration: 1335494772, states[0] = -94.232879, states[40]= 0.000000
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Iteration: 1342905160, states[0] = -94.188473, states[40]= 0.000000
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Iteration: 1350330107, states[0] = -94.093385, states[40]= 0.000000
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Iteration: 1357714797, states[0] = -93.617910, states[40]= 0.000000
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Iteration: 1365127305, states[0] = -26.815242, states[40]= 0.000360
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Iteration: 1372532401, states[0] = 25.305626, states[40]= 0.000000
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Iteration: 1379948984, states[0] = -94.215824, states[40]= 0.000000
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Iteration: 1387283058, states[0] = -94.221502, states[40]= 0.000000
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Iteration: 1394661354, states[0] = -94.226374, states[40]= 0.000000
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Iteration: 1401870112, states[0] = -94.240641, states[40]= 0.000000
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Iteration: 1409264971, states[0] = -94.245527, states[40]= 0.000000
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Iteration: 1416641552, states[0] = -94.247887, states[40]= 0.000000
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Iteration: 1423962245, states[0] = -94.220218, states[40]= 0.000000
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Iteration: 1431316965, states[0] = -94.064859, states[40]= 0.000000
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Iteration: 1438703774, states[0] = -93.530218, states[40]= 0.000000
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Iteration: 1446091739, states[0] = 6.485742, states[40]= 0.000073
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Iteration: 1453466830, states[0] = -94.213898, states[40]= 0.000000
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Iteration: 1460837477, states[0] = -94.218108, states[40]= 0.000000
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Iteration: 1468241878, states[0] = -94.221619, states[40]= 0.000000
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Iteration: 1475627706, states[0] = -94.226372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483013324, states[0] = -94.231721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490428555, states[0] = -94.235948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497830278, states[0] = -94.240886, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.087983
 - CaMKt in component CaMK (millimolar): 0.003733
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 7.215714
 - nass in component intracellular_ions (millimolar): 7.215860
 - ki in component intracellular_ions (millimolar): 144.392673
 - kss in component intracellular_ions (millimolar): 144.392655
 - cansr in component intracellular_ions (millimolar): 2.503678
 - cajsr in component intracellular_ions (millimolar): 2.504359
 - cai in component intracellular_ions (millimolar): 0.000107
 - m in component INa (dimensionless): 0.003928
 - hf in component INa (dimensionless): 0.865145
 - hs in component INa (dimensionless): 0.865146
 - j in component INa (dimensionless): 0.865153
 - hsp in component INa (dimensionless): 0.698465
 - jp in component INa (dimensionless): 0.865157
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707263
 - hLp in component INaL (dimensionless): 0.510926
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.999850
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999850
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.991510
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005603
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.024297
 - xs1 in component IKs (dimensionless): 0.067276
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997543
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:10:28 (418): called boinc_finish(0)

</stderr_txt>
]]>


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