𝕏

Task 55291832

Name HuVeMOp_20240629112358674907_ORdGradInc_k_25-Schmidt_750-conf_600_1
Workunit 26255039
Created 29 Jun 2024, 9:24:27 UTC
Sent 29 Jun 2024, 15:06:35 UTC
Report deadline 2 Jul 2024, 15:06:35 UTC
Received 30 Jun 2024, 4:37:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 231733
Run time 8 hours 56 min 38 sec
CPU time 8 hours 56 min 20 sec
Validate state Valid
Credit 43.17
Device peak FLOPS 1.26 GFLOPS
Application version Human ventricular cell models optimization v0.02
aarch64-unknown-linux-gnu
Peak working set size 2.20 MB
Peak swap size 11.11 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Schmidt_750-conf_600.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Schmidt_750-conf_600_1_r351292726_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Schmidt_750-conf_600_1_r351292726_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 93.342627
     * GNaL_b in INaL: 0.007249
     * Gto_b in Ito: 0.087531
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030529
     * GKs_b in IKs: 0.001914
     * GK1_b in IK1: 0.179668
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 71.913311
     * GKb_b in IKb: 0.003700
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036077
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4000.000000
     * CL_0 in membrane: 750.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499625000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 2795715, states[0] = -84.361852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 5590282, states[0] = -84.746043, states[40]= 0.000001
Saving checkpoint... 
Iteration: 8382501, states[0] = -47.249822, states[40]= 0.000065
Saving checkpoint... 
Iteration: 11175829, states[0] = -84.621065, states[40]= 0.000001
Saving checkpoint... 
Iteration: 13975964, states[0] = -13.332058, states[40]= 0.000377
Saving checkpoint... 
Iteration: 16772508, states[0] = -84.526093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 19566995, states[0] = 11.115651, states[40]= 0.000085
Saving checkpoint... 
Iteration: 22363814, states[0] = -84.391907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25161475, states[0] = 25.843161, states[40]= 0.000009
Saving checkpoint... 
Iteration: 27960695, states[0] = -84.236602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30758987, states[0] = 30.471847, states[40]= 0.087957
Saving checkpoint... 
Iteration: 33557408, states[0] = -84.021249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36355269, states[0] = -84.658050, states[40]= 0.000001
Saving checkpoint... 
Iteration: 39154051, states[0] = -71.214013, states[40]= 0.000002
Saving checkpoint... 
Iteration: 41953810, states[0] = -84.622045, states[40]= 0.000001
Saving checkpoint... 
Iteration: 44753408, states[0] = -41.248409, states[40]= 0.000081
Saving checkpoint... 
Iteration: 47553031, states[0] = -84.575282, states[40]= 0.000001
Saving checkpoint... 
Iteration: 50351037, states[0] = -13.265323, states[40]= 0.000234
Saving checkpoint... 
Iteration: 53149389, states[0] = -84.504156, states[40]= 0.000001
Saving checkpoint... 
Iteration: 55948144, states[0] = 7.938030, states[40]= 0.000101
Saving checkpoint... 
Iteration: 58729572, states[0] = -84.330416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61527618, states[0] = 29.369668, states[40]= 0.000118
Saving checkpoint... 
Iteration: 64325069, states[0] = -84.154707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67122089, states[0] = -84.669015, states[40]= 0.000001
Saving checkpoint... 
Iteration: 69919804, states[0] = -83.460817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72717795, states[0] = -84.636619, states[40]= 0.000001
Saving checkpoint... 
Iteration: 75516681, states[0] = -55.138813, states[40]= 0.000015
Saving checkpoint... 
Iteration: 78314616, states[0] = -84.593341, states[40]= 0.000001
Saving checkpoint... 
Iteration: 81112642, states[0] = -25.207859, states[40]= 0.000197
Saving checkpoint... 
Iteration: 83911501, states[0] = -84.533275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 86710457, states[0] = 0.462677, states[40]= 0.000229
Saving checkpoint... 
Iteration: 89509686, states[0] = -84.453588, states[40]= 0.000001
Saving checkpoint... 
Iteration: 92307812, states[0] = 16.084019, states[40]= 0.000029
Saving checkpoint... 
Iteration: 95105919, states[0] = -84.333700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97904169, states[0] = 28.846347, states[40]= 0.000069
Saving checkpoint... 
Iteration: 100701743, states[0] = -84.163241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103500495, states[0] = 4.468193, states[40]= 0.004848
Saving checkpoint... 
Iteration: 106297022, states[0] = -83.683322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109094635, states[0] = -84.636606, states[40]= 0.000001
Saving checkpoint... 
Iteration: 111892881, states[0] = -56.410205, states[40]= 0.000013
Saving checkpoint... 
Iteration: 114691683, states[0] = -84.594903, states[40]= 0.000001
Saving checkpoint... 
Iteration: 117489116, states[0] = -26.637503, states[40]= 0.000199
Saving checkpoint... 
Iteration: 120286351, states[0] = -84.531034, states[40]= 0.000001
Saving checkpoint... 
Iteration: 123083049, states[0] = 2.084753, states[40]= 0.000201
Saving checkpoint... 
Iteration: 125880869, states[0] = -84.438344, states[40]= 0.000001
Saving checkpoint... 
Iteration: 128678866, states[0] = 18.043666, states[40]= 0.000020
Saving checkpoint... 
Iteration: 131477940, states[0] = -84.317243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134276754, states[0] = 29.682285, states[40]= 0.000160
Saving checkpoint... 
Iteration: 137074489, states[0] = -84.146363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139871199, states[0] = -84.664220, states[40]= 0.000001
Saving checkpoint... 
Iteration: 142669215, states[0] = -83.348844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145467358, states[0] = -84.632493, states[40]= 0.000001
Saving checkpoint... 
Iteration: 148265764, states[0] = -53.993181, states[40]= 0.000018
Saving checkpoint... 
Iteration: 151062982, states[0] = -84.587173, states[40]= 0.000001
Saving checkpoint... 
Iteration: 153859982, states[0] = -22.421916, states[40]= 0.000191
Saving checkpoint... 
Iteration: 156657079, states[0] = -84.518970, states[40]= 0.000001
Saving checkpoint... 
Iteration: 159453514, states[0] = 4.900502, states[40]= 0.000151
Saving checkpoint... 
Iteration: 162251450, states[0] = -84.420807, states[40]= 0.000001
Saving checkpoint... 
Iteration: 165033327, states[0] = 27.276956, states[40]= 0.000018
Saving checkpoint... 
Iteration: 167830236, states[0] = -84.184311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170611366, states[0] = -84.653838, states[40]= 0.000001
Saving checkpoint... 
Iteration: 173409151, states[0] = -77.422022, states[40]= 0.000001
Saving checkpoint... 
Iteration: 176206890, states[0] = -84.617399, states[40]= 0.000001
Saving checkpoint... 
Iteration: 179004406, states[0] = -41.962695, states[40]= 0.000077
Saving checkpoint... 
Iteration: 181802111, states[0] = -84.565320, states[40]= 0.000001
Saving checkpoint... 
Iteration: 184599384, states[0] = -11.341975, states[40]= 0.000261
Saving checkpoint... 
Iteration: 187397559, states[0] = -84.491617, states[40]= 0.000001
Saving checkpoint... 
Iteration: 190196046, states[0] = 9.168489, states[40]= 0.000087
Saving checkpoint... 
Iteration: 192992793, states[0] = -84.385057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195792170, states[0] = 23.522000, states[40]= 0.000007
Saving checkpoint... 
Iteration: 198591401, states[0] = -84.252646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201389396, states[0] = 31.835597, states[40]= 0.012784
Saving checkpoint... 
Iteration: 204186178, states[0] = -84.043183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206986264, states[0] = -84.652940, states[40]= 0.000001
Saving checkpoint... 
Iteration: 209785286, states[0] = -78.663517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212584498, states[0] = -84.620354, states[40]= 0.000001
Saving checkpoint... 
Iteration: 215384348, states[0] = -47.066090, states[40]= 0.000043
Saving checkpoint... 
Iteration: 218183149, states[0] = -84.576612, states[40]= 0.000001
Saving checkpoint... 
Iteration: 220981120, states[0] = -18.402575, states[40]= 0.000195
Saving checkpoint... 
Iteration: 223779745, states[0] = -84.511234, states[40]= 0.000001
Saving checkpoint... 
Iteration: 226562303, states[0] = 13.817930, states[40]= 0.000043
Saving checkpoint... 
Iteration: 229361356, states[0] = -84.355729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232139364, states[0] = 31.833582, states[40]= 0.012930
Saving checkpoint... 
Iteration: 234939412, states[0] = -84.069717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237739907, states[0] = -84.655998, states[40]= 0.000001
Saving checkpoint... 
Iteration: 240540667, states[0] = -82.403932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243338217, states[0] = -84.624862, states[40]= 0.000001
Saving checkpoint... 
Iteration: 246135914, states[0] = -48.717206, states[40]= 0.000035
Saving checkpoint... 
Iteration: 248935248, states[0] = -84.579978, states[40]= 0.000001
Saving checkpoint... 
Iteration: 251734219, states[0] = -21.627243, states[40]= 0.000190
Saving checkpoint... 
Iteration: 254534983, states[0] = -84.524382, states[40]= 0.000001
Saving checkpoint... 
Iteration: 257334403, states[0] = 1.209741, states[40]= 0.000217
Saving checkpoint... 
Iteration: 260134140, states[0] = -84.446869, states[40]= 0.000001
Saving checkpoint... 
Iteration: 262934156, states[0] = 15.424157, states[40]= 0.000033
Saving checkpoint... 
Iteration: 265733387, states[0] = -84.341041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268534321, states[0] = 26.879889, states[40]= 0.000014
Saving checkpoint... 
Iteration: 271333604, states[0] = -84.203769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274133104, states[0] = 30.154429, states[40]= 0.120711
Saving checkpoint... 
Iteration: 276932579, states[0] = -84.005688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279731934, states[0] = -84.646866, states[40]= 0.000001
Saving checkpoint... 
Iteration: 282531229, states[0] = -73.657436, states[40]= 0.000001
Saving checkpoint... 
Iteration: 285329772, states[0] = -84.612013, states[40]= 0.000001
Saving checkpoint... 
Iteration: 288128877, states[0] = -41.417330, states[40]= 0.000081
Saving checkpoint... 
Iteration: 290928245, states[0] = -84.565396, states[40]= 0.000001
Saving checkpoint... 
Iteration: 293727362, states[0] = -14.436275, states[40]= 0.000226
Saving checkpoint... 
Iteration: 296528048, states[0] = -84.505095, states[40]= 0.000001
Saving checkpoint... 
Iteration: 299326910, states[0] = 5.851715, states[40]= 0.000135
Saving checkpoint... 
Iteration: 302126863, states[0] = -84.419423, states[40]= 0.000001
Saving checkpoint... 
Iteration: 304928127, states[0] = 18.408541, states[40]= 0.000019
Saving checkpoint... 
Iteration: 307729050, states[0] = -84.318913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310530192, states[0] = 28.483561, states[40]= 0.000049
Saving checkpoint... 
Iteration: 313331088, states[0] = -84.186768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316131662, states[0] = 29.657117, states[40]= 0.201154
Saving checkpoint... 
Iteration: 318932171, states[0] = -84.000043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321732777, states[0] = -84.646937, states[40]= 0.000001
Saving checkpoint... 
Iteration: 324534002, states[0] = -77.231034, states[40]= 0.000001
Saving checkpoint... 
Iteration: 327335275, states[0] = -84.619124, states[40]= 0.000001
Saving checkpoint... 
Iteration: 330134572, states[0] = -47.296334, states[40]= 0.000042
Saving checkpoint... 
Iteration: 332919970, states[0] = -84.546765, states[40]= 0.000001
Saving checkpoint... 
Iteration: 335720120, states[0] = -7.163099, states[40]= 0.000294
Saving checkpoint... 
Iteration: 338520223, states[0] = -84.481483, states[40]= 0.000001
Saving checkpoint... 
Iteration: 341321073, states[0] = 9.155886, states[40]= 0.000087
Saving checkpoint... 
Iteration: 344119671, states[0] = -84.389857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346918805, states[0] = 22.787577, states[40]= 0.000008
Saving checkpoint... 
Iteration: 349717343, states[0] = -84.254959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352517747, states[0] = 31.777851, states[40]= 0.003871
Saving checkpoint... 
Iteration: 355319375, states[0] = -84.105082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358118965, states[0] = -84.657515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 360918669, states[0] = -83.242833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363718561, states[0] = -84.629448, states[40]= 0.000001
Saving checkpoint... 
Iteration: 366518574, states[0] = -57.156446, states[40]= 0.000012
Saving checkpoint... 
Iteration: 369319379, states[0] = -84.593824, states[40]= 0.000001
Saving checkpoint... 
Iteration: 372117971, states[0] = -30.472373, states[40]= 0.000187
Saving checkpoint... 
Iteration: 374915940, states[0] = -84.536593, states[40]= 0.000001
Saving checkpoint... 
Iteration: 377713871, states[0] = -1.938585, states[40]= 0.000268
Saving checkpoint... 
Iteration: 380511772, states[0] = -84.453474, states[40]= 0.000001
Saving checkpoint... 
Iteration: 383311141, states[0] = 14.416290, states[40]= 0.000039
Saving checkpoint... 
Iteration: 386109233, states[0] = -84.342603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388907119, states[0] = 27.753988, states[40]= 0.000026
Saving checkpoint... 
Iteration: 391704236, states[0] = -84.173006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394500561, states[0] = 26.418220, states[40]= 0.038261
Saving checkpoint... 
Iteration: 397283858, states[0] = -77.054991, states[40]= 0.000001
Saving checkpoint... 
Iteration: 400079948, states[0] = -84.609974, states[40]= 0.000001
Saving checkpoint... 
Iteration: 402859073, states[0] = -21.472189, states[40]= 0.000190
Saving checkpoint... 
Iteration: 405655622, states[0] = -84.509917, states[40]= 0.000001
Saving checkpoint... 
Iteration: 408452826, states[0] = 5.314649, states[40]= 0.000144
Saving checkpoint... 
Iteration: 411251266, states[0] = -84.414918, states[40]= 0.000001
Saving checkpoint... 
Iteration: 414050060, states[0] = 19.882160, states[40]= 0.000014
Saving checkpoint... 
Iteration: 416849593, states[0] = -84.293660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419648313, states[0] = 30.715127, states[40]= 0.000537
Saving checkpoint... 
Iteration: 422446067, states[0] = -84.115995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425244849, states[0] = -84.657006, states[40]= 0.000001
Saving checkpoint... 
Iteration: 428043896, states[0] = -83.282738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430842734, states[0] = -84.627049, states[40]= 0.000001
Saving checkpoint... 
Iteration: 433641060, states[0] = -54.299748, states[40]= 0.000017
Saving checkpoint... 
Iteration: 436440164, states[0] = -84.585185, states[40]= 0.000001
Saving checkpoint... 
Iteration: 439239099, states[0] = -26.586361, states[40]= 0.000200
Saving checkpoint... 
Iteration: 442038627, states[0] = -84.529680, states[40]= 0.000001
Saving checkpoint... 
Iteration: 444837249, states[0] = -0.748051, states[40]= 0.000251
Saving checkpoint... 
Iteration: 447637463, states[0] = -84.454442, states[40]= 0.000001
Saving checkpoint... 
Iteration: 450437485, states[0] = 13.726146, states[40]= 0.000044
Saving checkpoint... 
Iteration: 453237890, states[0] = -84.358161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456037770, states[0] = 25.446831, states[40]= 0.000007
Saving checkpoint... 
Iteration: 458838304, states[0] = -84.228932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461639050, states[0] = 31.808905, states[40]= 0.014462
Saving checkpoint... 
Iteration: 464439486, states[0] = -84.065533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467241085, states[0] = -84.652562, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470042220, states[0] = -82.906916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472843036, states[0] = -84.626595, states[40]= 0.000001
Saving checkpoint... 
Iteration: 475643921, states[0] = -57.554101, states[40]= 0.000011
Saving checkpoint... 
Iteration: 478444749, states[0] = -84.592258, states[40]= 0.000001
Saving checkpoint... 
Iteration: 481248665, states[0] = -36.161592, states[40]= 0.000133
Saving checkpoint... 
Iteration: 484051177, states[0] = -84.557230, states[40]= 0.000001
Saving checkpoint... 
Iteration: 486854101, states[0] = -16.266375, states[40]= 0.000209
Saving checkpoint... 
Iteration: 489657538, states[0] = -84.513311, states[40]= 0.000001
Saving checkpoint... 
Iteration: 492460781, states[0] = 0.282096, states[40]= 0.000234
Saving checkpoint... 
Iteration: 495264994, states[0] = -84.461839, states[40]= 0.000001
Saving checkpoint... 
Iteration: 498067950, states[0] = 10.853020, states[40]= 0.000068
Saving checkpoint... 
Iteration: 500859502, states[0] = -84.341532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503662583, states[0] = 25.526780, states[40]= 0.000008
Saving checkpoint... 
Iteration: 506465270, states[0] = -84.239666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509267592, states[0] = 31.793503, states[40]= 0.004091
Saving checkpoint... 
Iteration: 512070289, states[0] = -84.108515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514873065, states[0] = -84.658175, states[40]= 0.000001
Saving checkpoint... 
Iteration: 517676629, states[0] = -83.896192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520479178, states[0] = -84.639003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 523280718, states[0] = -72.935093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 526082594, states[0] = -84.611330, states[40]= 0.000001
Saving checkpoint... 
Iteration: 528885076, states[0] = -47.820245, states[40]= 0.000039
Saving checkpoint... 
Iteration: 531687592, states[0] = -84.578639, states[40]= 0.000001
Saving checkpoint... 
Iteration: 534489393, states[0] = -26.879703, states[40]= 0.000200
Saving checkpoint... 
Iteration: 537291680, states[0] = -84.535070, states[40]= 0.000001
Saving checkpoint... 
Iteration: 540093538, states[0] = -5.730959, states[40]= 0.000295
Saving checkpoint... 
Iteration: 542897461, states[0] = -84.484087, states[40]= 0.000001
Saving checkpoint... 
Iteration: 545701213, states[0] = 6.259994, states[40]= 0.000128
Saving checkpoint... 
Iteration: 548504769, states[0] = -84.425327, states[40]= 0.000001
Saving checkpoint... 
Iteration: 551307353, states[0] = 16.331422, states[40]= 0.000028
Saving checkpoint... 
Iteration: 554109392, states[0] = -84.339927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556911929, states[0] = 25.804000, states[40]= 0.000008
Saving checkpoint... 
Iteration: 559714069, states[0] = -84.231447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562515780, states[0] = 31.883236, states[40]= 0.007801
Saving checkpoint... 
Iteration: 565306530, states[0] = -83.986939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568107958, states[0] = -84.642205, states[40]= 0.000001
Saving checkpoint... 
Iteration: 570910284, states[0] = -78.635477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573712174, states[0] = -84.616818, states[40]= 0.000001
Saving checkpoint... 
Iteration: 576503188, states[0] = -40.709242, states[40]= 0.000088
Saving checkpoint... 
Iteration: 579305240, states[0] = -84.563628, states[40]= 0.000001
Saving checkpoint... 
Iteration: 582106946, states[0] = -19.257408, states[40]= 0.000192
Saving checkpoint... 
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Iteration: 924090477, states[0] = -3.167706, states[40]= 0.000281
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Iteration: 929700896, states[0] = 6.447513, states[40]= 0.000125
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Iteration: 932505607, states[0] = -84.420612, states[40]= 0.000001
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Iteration: 935309683, states[0] = 15.163216, states[40]= 0.000034
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Iteration: 971747976, states[0] = -35.458268, states[40]= 0.000141
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Iteration: 982957549, states[0] = 2.427033, states[40]= 0.000195
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Iteration: 988563476, states[0] = 13.217652, states[40]= 0.000047
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Iteration: 991366892, states[0] = -84.364894, states[40]= 0.000000
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Iteration: 994169673, states[0] = 22.397566, states[40]= 0.000009
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Iteration: 996972443, states[0] = -84.270237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999775489, states[0] = 30.093275, states[40]= 0.000249
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Iteration: 1005371043, states[0] = -84.646528, states[40]= 0.000001
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Iteration: 1008173558, states[0] = -83.761431, states[40]= 0.000000
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Iteration: 1010976116, states[0] = -84.625688, states[40]= 0.000001
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Iteration: 1013779010, states[0] = -70.513406, states[40]= 0.000002
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Iteration: 1019384954, states[0] = -47.674898, states[40]= 0.000040
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Iteration: 1024988992, states[0] = -26.462545, states[40]= 0.000200
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Iteration: 1027790482, states[0] = -84.522352, states[40]= 0.000001
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Iteration: 1030592172, states[0] = -4.547281, states[40]= 0.000291
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Iteration: 1033394246, states[0] = -84.464432, states[40]= 0.000001
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Iteration: 1036196866, states[0] = 8.725109, states[40]= 0.000093
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Iteration: 1039000448, states[0] = -84.399004, states[40]= 0.000001
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Iteration: 1041803121, states[0] = 18.417224, states[40]= 0.000019
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Iteration: 1047406967, states[0] = 27.817891, states[40]= 0.000028
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Iteration: 1050208521, states[0] = -84.187210, states[40]= 0.000000
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Iteration: 1053011109, states[0] = 31.256042, states[40]= 0.041339
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Iteration: 1055813111, states[0] = -84.042051, states[40]= 0.000000
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Iteration: 1058614869, states[0] = -84.639544, states[40]= 0.000001
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Iteration: 1061416881, states[0] = -82.788661, states[40]= 0.000000
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Iteration: 1064219731, states[0] = -84.616903, states[40]= 0.000001
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Iteration: 1067022206, states[0] = -61.463394, states[40]= 0.000006
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Iteration: 1069814153, states[0] = -84.570663, states[40]= 0.000001
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Iteration: 1072616878, states[0] = -29.358949, states[40]= 0.000194
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Iteration: 1075419462, states[0] = -84.530665, states[40]= 0.000001
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Iteration: 1078222225, states[0] = -9.151856, states[40]= 0.000282
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Iteration: 1081025949, states[0] = -84.483356, states[40]= 0.000001
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Iteration: 1083828298, states[0] = 5.042631, states[40]= 0.000148
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Iteration: 1086631618, states[0] = -84.421154, states[40]= 0.000001
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Iteration: 1089435356, states[0] = 14.822769, states[40]= 0.000036
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Iteration: 1092239071, states[0] = -84.350450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095040928, states[0] = 24.080929, states[40]= 0.000007
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Iteration: 1097842934, states[0] = -84.243004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100645479, states[0] = 31.378327, states[40]= 0.001466
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Iteration: 1103447943, states[0] = -84.115292, states[40]= 0.000000
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Iteration: 1106249473, states[0] = -84.647624, states[40]= 0.000001
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Iteration: 1109051156, states[0] = -83.869003, states[40]= 0.000000
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Iteration: 1111851725, states[0] = -84.624377, states[40]= 0.000001
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Iteration: 1114653555, states[0] = -69.870014, states[40]= 0.000002
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Iteration: 1117455703, states[0] = -84.596715, states[40]= 0.000001
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Iteration: 1120257885, states[0] = -45.507403, states[40]= 0.000052
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Iteration: 1123058334, states[0] = -84.558767, states[40]= 0.000001
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Iteration: 1125859072, states[0] = -21.451234, states[40]= 0.000190
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Iteration: 1128660840, states[0] = -84.508925, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1131462725, states[0] = -1.079772, states[40]= 0.000255
Saving checkpoint... 
Iteration: 1134264086, states[0] = -84.445932, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1137065354, states[0] = 12.237351, states[40]= 0.000055
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Iteration: 1139866485, states[0] = -84.360109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142667243, states[0] = 23.496964, states[40]= 0.000007
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Iteration: 1145467616, states[0] = -84.240203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148269249, states[0] = 31.593510, states[40]= 0.002268
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Iteration: 1151072176, states[0] = -84.108870, states[40]= 0.000000
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Iteration: 1153874107, states[0] = -84.646346, states[40]= 0.000001
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Iteration: 1156676309, states[0] = -83.872641, states[40]= 0.000000
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Iteration: 1159478239, states[0] = -84.625160, states[40]= 0.000001
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Iteration: 1162279814, states[0] = -71.628960, states[40]= 0.000001
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Iteration: 1165080793, states[0] = -84.595894, states[40]= 0.000001
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Iteration: 1167883250, states[0] = -45.885445, states[40]= 0.000050
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Iteration: 1170684748, states[0] = -84.560510, states[40]= 0.000001
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Iteration: 1173476035, states[0] = -13.020423, states[40]= 0.000242
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Iteration: 1176278786, states[0] = -84.489372, states[40]= 0.000001
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Iteration: 1179081126, states[0] = 3.325698, states[40]= 0.000179
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Iteration: 1181883297, states[0] = -84.425217, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1184685764, states[0] = 14.615648, states[40]= 0.000038
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Iteration: 1187487990, states[0] = -84.343647, states[40]= 0.000000
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Iteration: 1190290533, states[0] = 24.255706, states[40]= 0.000007
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Iteration: 1193092028, states[0] = -84.235835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195893380, states[0] = 31.714294, states[40]= 0.003090
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Iteration: 1198695812, states[0] = -84.098102, states[40]= 0.000000
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Iteration: 1201497995, states[0] = -84.644395, states[40]= 0.000001
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Iteration: 1204300229, states[0] = -83.834774, states[40]= 0.000000
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Iteration: 1207101156, states[0] = -84.621811, states[40]= 0.000001
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Iteration: 1209902395, states[0] = -68.253034, states[40]= 0.000002
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Iteration: 1212704547, states[0] = -84.593086, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1215506840, states[0] = -44.422327, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1218309343, states[0] = -84.558785, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1221112417, states[0] = -24.866466, states[40]= 0.000197
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Iteration: 1223915445, states[0] = -84.518312, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1226718021, states[0] = -5.265896, states[40]= 0.000294
Saving checkpoint... 
Iteration: 1229519985, states[0] = -84.462739, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1232322059, states[0] = 8.620099, states[40]= 0.000094
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Iteration: 1235124557, states[0] = -84.391534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237915798, states[0] = 24.139377, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1240717603, states[0] = -84.238173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243520261, states[0] = 31.420968, states[40]= 0.001583
Saving checkpoint... 
Iteration: 1246323460, states[0] = -84.115980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249125535, states[0] = 21.597750, states[40]= 0.022861
Saving checkpoint... 
Iteration: 1251926519, states[0] = -83.876736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254727239, states[0] = -84.622111, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1257527950, states[0] = -69.017712, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1260330252, states[0] = -84.593183, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1263132487, states[0] = -45.089854, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1265933964, states[0] = -84.557105, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1268734442, states[0] = -21.828669, states[40]= 0.000190
Saving checkpoint... 
Iteration: 1271535774, states[0] = -84.505878, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1274335935, states[0] = 0.187960, states[40]= 0.000235
Saving checkpoint... 
Iteration: 1277136098, states[0] = -84.433018, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1279936711, states[0] = 14.131676, states[40]= 0.000041
Saving checkpoint... 
Iteration: 1282736551, states[0] = -84.335134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285537293, states[0] = 25.655801, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1288337258, states[0] = -84.205548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291136484, states[0] = 31.360704, states[40]= 0.036152
Saving checkpoint... 
Iteration: 1293936779, states[0] = -84.025755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296735722, states[0] = -84.630563, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1299535816, states[0] = -79.120682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302336341, states[0] = -84.601075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1305137166, states[0] = -50.014482, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1307936886, states[0] = -84.561751, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1310737177, states[0] = -24.620770, states[40]= 0.000197
Saving checkpoint... 
Iteration: 1313537507, states[0] = -84.509364, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1316336957, states[0] = -0.526047, states[40]= 0.000247
Saving checkpoint... 
Iteration: 1319136522, states[0] = -84.433611, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1321936416, states[0] = 14.283367, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1324737257, states[0] = -84.337516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327537634, states[0] = 25.511392, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1330319412, states[0] = -84.085175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333118795, states[0] = -84.637871, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1335919810, states[0] = -83.403220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338721028, states[0] = -84.613023, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1341511809, states[0] = -49.631254, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1344309308, states[0] = -84.556186, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1347110382, states[0] = -22.791430, states[40]= 0.000192
Saving checkpoint... 
Iteration: 1349911394, states[0] = -84.505858, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Schmidt_750-conf_600.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Schmidt_750-conf_600_1_r351292726_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-Schmidt_750-conf_600_1_r351292726_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 93.342627
     * GNaL_b in INaL: 0.007249
     * Gto_b in Ito: 0.087531
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030529
     * GKs_b in IKs: 0.001914
     * GK1_b in IK1: 0.179668
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 71.913311
     * GKb_b in IKb: 0.003700
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036077
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4000.000000
     * CL_0 in membrane: 750.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499625000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1349911394
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -84.505858 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1352695353, states[0] = 9.560519, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1355478182, states[0] = -84.293103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358261686, states[0] = 31.412834, states[40]= 0.033634
Saving checkpoint... 
Iteration: 1361044006, states[0] = -83.273573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363827483, states[0] = -84.586924, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1366609607, states[0] = -21.995756, states[40]= 0.000190
Saving checkpoint... 
Iteration: 1369398106, states[0] = -84.469291, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1372185076, states[0] = 14.967476, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1374971112, states[0] = -84.255196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377758112, states[0] = 30.161505, states[40]= 0.120313
Saving checkpoint... 
Iteration: 1380544996, states[0] = -83.428200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383332782, states[0] = -84.594422, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1386119789, states[0] = -32.261804, states[40]= 0.000173
Saving checkpoint... 
Iteration: 1388907536, states[0] = -84.495164, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1391694323, states[0] = 10.121366, states[40]= 0.000076
Saving checkpoint... 
Iteration: 1394482899, states[0] = -84.315656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397270455, states[0] = 31.385167, states[40]= 0.001478
Saving checkpoint... 
Iteration: 1400058276, states[0] = -83.989830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402847432, states[0] = -84.613461, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1405637076, states[0] = -49.914486, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1408424287, states[0] = -84.534625, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1411211531, states[0] = -0.224252, states[40]= 0.000242
Saving checkpoint... 
Iteration: 1414000128, states[0] = -84.390138, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1416787840, states[0] = 25.424333, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1419575899, states[0] = -84.129323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422363048, states[0] = -84.630443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1425150858, states[0] = -66.149306, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1427939266, states[0] = -84.563674, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1430727833, states[0] = -14.901417, states[40]= 0.000221
Saving checkpoint... 
Iteration: 1433516807, states[0] = -84.448685, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1436304613, states[0] = 17.692995, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1439093250, states[0] = -84.237809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441863955, states[0] = -84.630969, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1444651562, states[0] = -67.098009, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1447439562, states[0] = -84.563813, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1450228032, states[0] = -15.110824, states[40]= 0.000219
Saving checkpoint... 
Iteration: 1453017530, states[0] = -84.450583, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1455806421, states[0] = 16.802168, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1458594953, states[0] = -84.247036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461381288, states[0] = 29.583131, states[40]= 0.229390
Saving checkpoint... 
Iteration: 1464168901, states[0] = -83.251518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466956893, states[0] = -84.591456, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1469743392, states[0] = -30.863075, states[40]= 0.000184
Saving checkpoint... 
Iteration: 1472532522, states[0] = -84.493440, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1475322658, states[0] = 8.289359, states[40]= 0.000098
Saving checkpoint... 
Iteration: 1478112541, states[0] = -84.335684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480901326, states[0] = 29.833802, states[40]= 0.000186
Saving checkpoint... 
Iteration: 1483691571, states[0] = -84.060691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486479198, states[0] = -84.619702, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1489268394, states[0] = -56.899677, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1492056840, states[0] = -84.548446, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1494846010, states[0] = -7.970000, states[40]= 0.000290
Saving checkpoint... 
Iteration: 1497635358, states[0] = -84.426010, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.516060
 - CaMKt in component CaMK (millimolar): 0.030529
 - cass in component intracellular_ions (millimolar): 0.000098
 - nai in component intracellular_ions (millimolar): 6.721009
 - nass in component intracellular_ions (millimolar): 6.721149
 - ki in component intracellular_ions (millimolar): 144.980816
 - kss in component intracellular_ions (millimolar): 144.980790
 - cansr in component intracellular_ions (millimolar): 1.947515
 - cajsr in component intracellular_ions (millimolar): 1.774030
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.010293
 - hf in component INa (dimensionless): 0.571000
 - hs in component INa (dimensionless): 0.570904
 - j in component INa (dimensionless): 0.570393
 - hsp in component INa (dimensionless): 0.324303
 - jp in component INa (dimensionless): 0.570008
 - mL in component INaL (dimensionless): 0.000356
 - hL in component INaL (dimensionless): 0.360401
 - hLp in component INaL (dimensionless): 0.159698
 - a in component Ito (dimensionless): 0.001256
 - iF in component Ito (dimensionless): 0.999197
 - iS in component Ito (dimensionless): 0.410802
 - ap in component Ito (dimensionless): 0.000640
 - iFp in component Ito (dimensionless): 0.999197
 - iSp in component Ito (dimensionless): 0.446619
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.858140
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.997770
 - jca in component ICaL (dimensionless): 0.999240
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004839
 - xrf in component IKr (dimensionless): 0.000118
 - xrs in component IKr (dimensionless): 0.633515
 - xs1 in component IKs (dimensionless): 0.363978
 - xs2 in component IKs (dimensionless): 0.000281
 - xk1 in component IK1 (dimensionless): 0.996796
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
05:30:10 (5053): called boinc_finish(0)

</stderr_txt>
]]>


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