𝕏

Task 55286726

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-Schmidt_3000-conf_587_0
Workunit 26252488
Created 29 Jun 2024, 9:21:47 UTC
Sent 29 Jun 2024, 14:11:59 UTC
Report deadline 2 Jul 2024, 14:11:59 UTC
Received 29 Jun 2024, 23:05:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 50 min 49 sec
CPU time 1 hours 45 min 55 sec
Validate state Valid
Credit 45.63
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.21 MB
Peak swap size 4.13 GB
Peak disk usage 0.95 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Schmidt_3000-conf_587.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Schmidt_3000-conf_587_0_r901420112_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Schmidt_3000-conf_587_0_r901420112_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 107.623232
     * GNaL_b in INaL: 0.004915
     * Gto_b in Ito: 0.079580
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033449
     * GKs_b in IKs: 0.002111
     * GK1_b in IK1: 0.164354
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.174315
     * GKb_b in IKb: 0.003673
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037651
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1498500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11272924, states[0] = -84.258039, states[40]= 0.000001
Saving checkpoint... 
Iteration: 22486810, states[0] = -84.135311, states[40]= 0.000001
Saving checkpoint... 
Iteration: 33843627, states[0] = -84.112071, states[40]= 0.000001
Saving checkpoint... 
Iteration: 45191930, states[0] = -82.754458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56863966, states[0] = -84.042973, states[40]= 0.000001
Saving checkpoint... 
Iteration: 67989541, states[0] = -84.011850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 80278031, states[0] = -84.047331, states[40]= 0.000001
Saving checkpoint... 
Iteration: 91992955, states[0] = -83.998145, states[40]= 0.000001
Saving checkpoint... 
Iteration: 103740155, states[0] = -83.447746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114051810, states[0] = 21.642335, states[40]= 0.000077
Saving checkpoint... 
Iteration: 125309524, states[0] = -84.030255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 136432966, states[0] = -83.999905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 146968793, states[0] = -83.997178, states[40]= 0.000001
Saving checkpoint... 
Iteration: 157651246, states[0] = -45.334980, states[40]= 0.000100
Saving checkpoint... 
Iteration: 167831194, states[0] = -84.000866, states[40]= 0.000001
Saving checkpoint... 
Iteration: 177654098, states[0] = -84.021937, states[40]= 0.000001
Saving checkpoint... 
Iteration: 187955032, states[0] = -83.959231, states[40]= 0.000001
Saving checkpoint... 
Iteration: 198873090, states[0] = -84.021713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 208368770, states[0] = -83.997523, states[40]= 0.000001
Saving checkpoint... 
Iteration: 218795563, states[0] = -84.000446, states[40]= 0.000001
Saving checkpoint... 
Iteration: 229700745, states[0] = -83.054807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240683111, states[0] = -84.022116, states[40]= 0.000001
Saving checkpoint... 
Iteration: 251947705, states[0] = -83.993628, states[40]= 0.000001
Saving checkpoint... 
Iteration: 262227569, states[0] = -84.002992, states[40]= 0.000001
Saving checkpoint... 
Iteration: 272451946, states[0] = -84.016936, states[40]= 0.000001
Saving checkpoint... 
Iteration: 283731465, states[0] = -83.383475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294140343, states[0] = -35.232676, states[40]= 0.000329
Saving checkpoint... 
Iteration: 304464069, states[0] = -83.992605, states[40]= 0.000001
Saving checkpoint... 
Iteration: 314907593, states[0] = -83.994733, states[40]= 0.000001
Saving checkpoint... 
Iteration: 325618768, states[0] = -15.029577, states[40]= 0.000617
Saving checkpoint... 
Iteration: 336720619, states[0] = -84.022708, states[40]= 0.000001
Saving checkpoint... 
Iteration: 346696353, states[0] = -82.763468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357261044, states[0] = -83.542390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368519105, states[0] = -84.013004, states[40]= 0.000001
Saving checkpoint... 
Iteration: 378931755, states[0] = -84.017369, states[40]= 0.000001
Saving checkpoint... 
Iteration: 390087504, states[0] = 6.604833, states[40]= 0.000589
Saving checkpoint... 
Iteration: 401138280, states[0] = -84.017799, states[40]= 0.000001
Saving checkpoint... 
Iteration: 411509479, states[0] = -83.987462, states[40]= 0.000001
Saving checkpoint... 
Iteration: 422117822, states[0] = -84.015310, states[40]= 0.000001
Saving checkpoint... 
Iteration: 432402480, states[0] = -83.907881, states[40]= 0.000001
Saving checkpoint... 
Iteration: 442511682, states[0] = 30.686384, states[40]= 0.030224
Saving checkpoint... 
Iteration: 452957292, states[0] = -83.992236, states[40]= 0.000001
Saving checkpoint... 
Iteration: 463245454, states[0] = -84.001183, states[40]= 0.000001
Saving checkpoint... 
Iteration: 473629337, states[0] = -84.006866, states[40]= 0.000001
Saving checkpoint... 
Iteration: 483702122, states[0] = -84.021645, states[40]= 0.000001
Saving checkpoint... 
Iteration: 494902178, states[0] = -83.994226, states[40]= 0.000001
Saving checkpoint... 
Iteration: 504408547, states[0] = -83.914607, states[40]= 0.000001
Saving checkpoint... 
Iteration: 514863717, states[0] = -83.851684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 524970634, states[0] = -83.991467, states[40]= 0.000001
Saving checkpoint... 
Iteration: 534563010, states[0] = -84.004667, states[40]= 0.000001
Saving checkpoint... 
Iteration: 543714845, states[0] = -84.021786, states[40]= 0.000001
Saving checkpoint... 
Iteration: 555272207, states[0] = -83.592337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566157037, states[0] = -84.018875, states[40]= 0.000001
Saving checkpoint... 
Iteration: 576766445, states[0] = -84.022030, states[40]= 0.000001
Saving checkpoint... 
Iteration: 587836072, states[0] = -83.996632, states[40]= 0.000001
Saving checkpoint... 
Iteration: 598794694, states[0] = -83.679249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609990001, states[0] = -84.013601, states[40]= 0.000001
Saving checkpoint... 
Iteration: 620974398, states[0] = -83.990970, states[40]= 0.000001
Saving checkpoint... 
Iteration: 632950255, states[0] = -83.991832, states[40]= 0.000001
Saving checkpoint... 
Iteration: 643685581, states[0] = -79.086532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654150950, states[0] = -44.895574, states[40]= 0.000107
Saving checkpoint... 
Iteration: 664793771, states[0] = -83.675792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676109394, states[0] = -84.007140, states[40]= 0.000001
Saving checkpoint... 
Iteration: 686287886, states[0] = -84.021366, states[40]= 0.000001
Saving checkpoint... 
Iteration: 696881560, states[0] = -84.018435, states[40]= 0.000001
Saving checkpoint... 
Iteration: 707924806, states[0] = -83.992536, states[40]= 0.000001
Saving checkpoint... 
Iteration: 719543423, states[0] = -84.010418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 730706894, states[0] = -83.199936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741814425, states[0] = -84.020590, states[40]= 0.000001
Saving checkpoint... 
Iteration: 751649547, states[0] = -43.615800, states[40]= 0.000126
Saving checkpoint... 
Iteration: 762459015, states[0] = -83.958480, states[40]= 0.000001
Saving checkpoint... 
Iteration: 773576825, states[0] = -84.008470, states[40]= 0.000001
Saving checkpoint... 
Iteration: 785302637, states[0] = -84.020713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 796434742, states[0] = -83.991820, states[40]= 0.000001
Saving checkpoint... 
Iteration: 807941399, states[0] = -84.015304, states[40]= 0.000001
Saving checkpoint... 
Iteration: 818972841, states[0] = -83.990292, states[40]= 0.000001
Saving checkpoint... 
Iteration: 830407861, states[0] = -84.016797, states[40]= 0.000001
Saving checkpoint... 
Iteration: 841032118, states[0] = -84.010558, states[40]= 0.000001
Saving checkpoint... 
Iteration: 852015162, states[0] = 31.133687, states[40]= 0.008924
Saving checkpoint... 
Iteration: 862651348, states[0] = -45.257077, states[40]= 0.000102
Saving checkpoint... 
Iteration: 873106079, states[0] = -3.944227, states[40]= 0.001032
Saving checkpoint... 
Iteration: 883832450, states[0] = -83.786787, states[40]= 0.000001
Saving checkpoint... 
Iteration: 894462943, states[0] = -83.960655, states[40]= 0.000001
Saving checkpoint... 
Iteration: 905230931, states[0] = -84.020737, states[40]= 0.000001
Saving checkpoint... 
Iteration: 916435538, states[0] = -83.991343, states[40]= 0.000001
Saving checkpoint... 
Iteration: 927518331, states[0] = -83.989152, states[40]= 0.000001
Saving checkpoint... 
Iteration: 938479722, states[0] = -84.012908, states[40]= 0.000001
Saving checkpoint... 
Iteration: 948910280, states[0] = -84.016248, states[40]= 0.000001
Saving checkpoint... 
Iteration: 960164354, states[0] = -57.322538, states[40]= 0.000018
Saving checkpoint... 
Iteration: 971750464, states[0] = -83.999058, states[40]= 0.000001
Saving checkpoint... 
Iteration: 982151939, states[0] = -84.003827, states[40]= 0.000001
Saving checkpoint... 
Iteration: 992791078, states[0] = -83.997111, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1003095606, states[0] = -84.006640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1013168093, states[0] = -84.018016, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1023656683, states[0] = -84.017152, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1034555740, states[0] = -84.008604, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1048342167, states[0] = -83.994658, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1063072255, states[0] = -84.007635, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1076565187, states[0] = -84.007954, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1087334496, states[0] = -83.994843, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1097738969, states[0] = -83.999131, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1107541288, states[0] = -83.996497, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1118935405, states[0] = -83.990595, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1129227421, states[0] = -83.999564, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1139286579, states[0] = -84.019709, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1150289089, states[0] = -83.996616, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1160417511, states[0] = -84.015132, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1170534586, states[0] = -83.994111, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1181838919, states[0] = -83.994301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1193367396, states[0] = -84.017166, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1205114108, states[0] = -84.011899, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1216643739, states[0] = -38.321836, states[40]= 0.000239
Saving checkpoint... 
Iteration: 1228194860, states[0] = -84.000774, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1240356823, states[0] = -83.993321, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1252606249, states[0] = -4.066090, states[40]= 0.001031
Saving checkpoint... 
Iteration: 1264826943, states[0] = -83.771959, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1275833300, states[0] = -84.018069, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1286461239, states[0] = -84.012551, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1297358664, states[0] = -83.993032, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1307723606, states[0] = -83.999083, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1319995008, states[0] = -83.987616, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1332540222, states[0] = -83.995330, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1344556452, states[0] = -83.999980, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1357280808, states[0] = -83.996223, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1369975646, states[0] = -83.966857, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1382066050, states[0] = -84.002268, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1394401596, states[0] = -84.014988, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1405730225, states[0] = -83.371611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416956540, states[0] = -84.012301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1429109350, states[0] = -84.004347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1440904995, states[0] = -84.014664, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1453712018, states[0] = -83.251691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465880155, states[0] = -83.874419, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1478419453, states[0] = -84.013863, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1490843146, states[0] = -83.992972, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -83.862725
 - CaMKt in component CaMK (millimolar): 0.002712
 - cass in component intracellular_ions (millimolar): 0.000090
 - nai in component intracellular_ions (millimolar): 6.269851
 - nass in component intracellular_ions (millimolar): 6.269960
 - ki in component intracellular_ions (millimolar): 145.611888
 - kss in component intracellular_ions (millimolar): 145.611875
 - cansr in component intracellular_ions (millimolar): 1.673570
 - cajsr in component intracellular_ions (millimolar): 1.673649
 - cai in component intracellular_ions (millimolar): 0.000094
 - m in component INa (dimensionless): 0.010990
 - hf in component INa (dimensionless): 0.544524
 - hs in component INa (dimensionless): 0.544528
 - j in component INa (dimensionless): 0.544545
 - hsp in component INa (dimensionless): 0.301510
 - jp in component INa (dimensionless): 0.544555
 - mL in component INaL (dimensionless): 0.000404
 - hL in component INaL (dimensionless): 0.381464
 - hLp in component INaL (dimensionless): 0.211095
 - a in component Ito (dimensionless): 0.001312
 - iF in component Ito (dimensionless): 0.999100
 - iS in component Ito (dimensionless): 0.948817
 - ap in component Ito (dimensionless): 0.000669
 - iFp in component Ito (dimensionless): 0.999100
 - iSp in component Ito (dimensionless): 0.962950
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.991139
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003494
 - xrf in component IKr (dimensionless): 0.000014
 - xrs in component IKr (dimensionless): 0.085765
 - xs1 in component IKs (dimensionless): 0.069879
 - xs2 in component IKs (dimensionless): 0.000302
 - xk1 in component IK1 (dimensionless): 0.996951
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
18:03:58 (88446): called boinc_finish(0)

</stderr_txt>
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