𝕏

Task 55286072

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-Coppini_1000-conf_184_0
Workunit 26252163
Created 29 Jun 2024, 9:21:21 UTC
Sent 29 Jun 2024, 14:02:29 UTC
Report deadline 2 Jul 2024, 14:02:29 UTC
Received 29 Jun 2024, 20:49:05 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238165
Run time 2 hours 40 min 45 sec
CPU time 2 hours 34 min 44 sec
Validate state Valid
Credit 40.89
Device peak FLOPS 2.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
aarch64-unknown-linux-gnu
Peak working set size 2.13 MB
Peak swap size 11.14 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Coppini_1000-conf_184.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Coppini_1000-conf_184_0_r1752841462_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Coppini_1000-conf_184_0_r1752841462_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 113.213412
     * GNaL_b in INaL: 0.005684
     * Gto_b in Ito: 0.094859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030129
     * GKs_b in IKs: 0.002076
     * GK1_b in IK1: 0.178261
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 74.047205
     * GKb_b in IKb: 0.003852
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019956
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9844333, states[0] = -95.096202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19793703, states[0] = -94.986519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29665471, states[0] = -84.228251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39509316, states[0] = 26.734827, states[40]= 0.063722
Saving checkpoint... 
Iteration: 49256866, states[0] = -94.874430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59124739, states[0] = -33.932064, states[40]= 0.000785
Saving checkpoint... 
Iteration: 68939678, states[0] = -95.060632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78863889, states[0] = -95.018434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88820651, states[0] = -94.975515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98763573, states[0] = -94.880157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108675993, states[0] = -93.455346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118543926, states[0] = 19.942437, states[40]= 0.002329
Saving checkpoint... 
Iteration: 128360493, states[0] = -95.012178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138283593, states[0] = -94.918302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148224650, states[0] = -94.770085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158186868, states[0] = -94.586285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168069401, states[0] = 9.619765, states[40]= 0.004291
Saving checkpoint... 
Iteration: 178049145, states[0] = 18.051433, states[40]= 0.002720
Saving checkpoint... 
Iteration: 187484530, states[0] = -95.067202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197287494, states[0] = -94.924287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207146104, states[0] = -54.575151, states[40]= 0.000050
Saving checkpoint... 
Iteration: 217073173, states[0] = 7.795981, states[40]= 0.004505
Saving checkpoint... 
Iteration: 226972192, states[0] = -95.063963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236937395, states[0] = -95.053199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246936327, states[0] = -95.052758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256902341, states[0] = -95.037756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266774696, states[0] = -94.900404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276596196, states[0] = -7.104351, states[40]= 0.003361
Saving checkpoint... 
Iteration: 286492869, states[0] = -95.068457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296477511, states[0] = -95.064972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306423822, states[0] = -95.047580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316312660, states[0] = -94.961392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326221114, states[0] = -94.756618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336129236, states[0] = -37.621079, states[40]= 0.000533
Saving checkpoint... 
Iteration: 346064264, states[0] = 11.958107, states[40]= 0.003935
Saving checkpoint... 
Iteration: 356018393, states[0] = 26.791075, states[40]= 0.004023
Saving checkpoint... 
Iteration: 365968119, states[0] = -95.062299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375965149, states[0] = -95.061452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385909244, states[0] = -95.040689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395878783, states[0] = -95.023380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405936328, states[0] = -95.052102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415842832, states[0] = -94.994717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425727333, states[0] = -94.777425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435601590, states[0] = -11.973302, states[40]= 0.002276
Saving checkpoint... 
Iteration: 445586718, states[0] = 0.076349, states[40]= 0.004599
Saving checkpoint... 
Iteration: 455571868, states[0] = 8.442783, states[40]= 0.004437
Saving checkpoint... 
Iteration: 465610940, states[0] = -20.790306, states[40]= 0.001332
Saving checkpoint... 
Iteration: 475665723, states[0] = -80.891537, states[40]= 0.000001
Saving checkpoint... 
Iteration: 485651722, states[0] = -60.749594, states[40]= 0.000018
Saving checkpoint... 
Iteration: 495603372, states[0] = -13.651087, states[40]= 0.001970
Saving checkpoint... 
Iteration: 505466348, states[0] = -95.061268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515569117, states[0] = 9.759874, states[40]= 0.004274
Saving checkpoint... 
Iteration: 525499846, states[0] = -95.068894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535464052, states[0] = -95.060517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545510160, states[0] = 26.829768, states[40]= 0.048066
Saving checkpoint... 
Iteration: 555558699, states[0] = 14.317684, states[40]= 0.003496
Saving checkpoint... 
Iteration: 565609582, states[0] = -19.522883, states[40]= 0.001371
Saving checkpoint... 
Iteration: 575531581, states[0] = 24.023491, states[40]= 0.001661
Saving checkpoint... 
Iteration: 585439674, states[0] = -95.052607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595414400, states[0] = -95.042295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605443121, states[0] = -95.053737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615435892, states[0] = -95.051112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625451061, states[0] = -95.056289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635483108, states[0] = -95.064945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645482657, states[0] = -95.064802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655364414, states[0] = -95.012167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665312140, states[0] = -94.959322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675295993, states[0] = -94.936154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685299073, states[0] = -94.940841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695277878, states[0] = -94.904837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705259887, states[0] = -94.866980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715194617, states[0] = -94.647338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725168122, states[0] = -85.193618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735066036, states[0] = 11.172961, states[40]= 0.004066
Saving checkpoint... 
Iteration: 744991004, states[0] = -95.066247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754989253, states[0] = -95.065835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764960798, states[0] = -95.058687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774918201, states[0] = -95.043301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784818736, states[0] = -94.967206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794612619, states[0] = -22.343730, states[40]= 0.001311
Saving checkpoint... 
Iteration: 804505192, states[0] = 29.461941, states[40]= 0.250211
Saving checkpoint... 
Iteration: 814251041, states[0] = -94.845008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824181148, states[0] = -94.372233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834135779, states[0] = -43.931652, states[40]= 0.000238
Saving checkpoint... 
Iteration: 844203632, states[0] = -94.687504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854153013, states[0] = -62.244094, states[40]= 0.000014
Saving checkpoint... 
Iteration: 864063554, states[0] = 12.268647, states[40]= 0.003882
Saving checkpoint... 
Iteration: 873937359, states[0] = -95.050630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883783475, states[0] = -94.914405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893747062, states[0] = -94.834296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903731061, states[0] = -94.787584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913737796, states[0] = -94.808179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923756641, states[0] = -94.858449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933814022, states[0] = -94.960700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943680472, states[0] = -94.313957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953513943, states[0] = 26.968783, states[40]= 0.014056
Saving checkpoint... 
Iteration: 963245206, states[0] = -94.829012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973139656, states[0] = -47.833051, states[40]= 0.000138
Saving checkpoint... 
Iteration: 983002095, states[0] = 44.326560, states[40]= 0.441800
Saving checkpoint... 
Iteration: 992834779, states[0] = -94.984441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002693603, states[0] = -94.640759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012506364, states[0] = 27.868713, states[40]= 0.170475
Saving checkpoint... 
Iteration: 1022310066, states[0] = -94.955152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032055773, states[0] = 15.501263, states[40]= 0.003256
Saving checkpoint... 
Iteration: 1041783942, states[0] = -94.914608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051735720, states[0] = -94.801424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061607109, states[0] = -17.192495, states[40]= 0.001518
Saving checkpoint... 
Iteration: 1071504104, states[0] = 32.390148, states[40]= 0.350574
Saving checkpoint... 
Iteration: 1081402219, states[0] = -95.034409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091248896, states[0] = -94.838355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100951357, states[0] = -95.054503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110669016, states[0] = -86.687193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120548461, states[0] = 18.310937, states[40]= 0.002669
Saving checkpoint... 
Iteration: 1130501501, states[0] = 48.605519, states[40]= 0.313826
Saving checkpoint... 
Iteration: 1140491489, states[0] = -95.064786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150507721, states[0] = 27.089153, states[40]= 0.108497
Saving checkpoint... 
Iteration: 1160319902, states[0] = -94.967133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170060295, states[0] = 13.657180, states[40]= 0.003626
Saving checkpoint... 
Iteration: 1179761272, states[0] = -94.868273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189612723, states[0] = -22.438274, states[40]= 0.001311
Saving checkpoint... 
Iteration: 1199537129, states[0] = 22.297730, states[40]= 0.001914
Saving checkpoint... 
Iteration: 1209078311, states[0] = 5.115883, states[40]= 0.004697
Saving checkpoint... 
Iteration: 1218625159, states[0] = -33.819564, states[40]= 0.000800
Saving checkpoint... 
Iteration: 1228216806, states[0] = -94.737505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237634859, states[0] = -43.021959, states[40]= 0.000270
Saving checkpoint... 
Iteration: 1246764473, states[0] = -94.875184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256110997, states[0] = -20.840603, states[40]= 0.001331
Saving checkpoint... 
Iteration: 1265528360, states[0] = 24.914858, states[40]= 0.001588
Saving checkpoint... 
Iteration: 1275105725, states[0] = -15.880016, states[40]= 0.001653
Saving checkpoint... 
Iteration: 1284671779, states[0] = -90.470356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294240398, states[0] = -94.814236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303752092, states[0] = -94.845724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313098537, states[0] = -9.161590, states[40]= 0.002884
Saving checkpoint... 
Iteration: 1322469660, states[0] = -95.058925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331548643, states[0] = 18.243526, states[40]= 0.002683
Saving checkpoint... 
Iteration: 1341020793, states[0] = 26.499694, states[40]= 0.002496
Saving checkpoint... 
Iteration: 1350677114, states[0] = -93.749825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360217112, states[0] = -94.738097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369635943, states[0] = -44.091949, states[40]= 0.000233
Saving checkpoint... 
Iteration: 1379119534, states[0] = -28.663315, states[40]= 0.001165
Saving checkpoint... 
Iteration: 1388241520, states[0] = -94.817063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397314254, states[0] = -94.959157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406578548, states[0] = 4.986307, states[40]= 0.004703
Saving checkpoint... 
Iteration: 1416050960, states[0] = 17.372429, states[40]= 0.002865
Saving checkpoint... 
Iteration: 1425551783, states[0] = 17.058602, states[40]= 0.002931
Saving checkpoint... 
Iteration: 1434921303, states[0] = -95.042043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444517530, states[0] = 26.865649, states[40]= 0.004977
Saving checkpoint... 
Iteration: 1453858699, states[0] = -95.004519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463134546, states[0] = -42.713723, states[40]= 0.000281
Saving checkpoint... 
Iteration: 1472413811, states[0] = -95.038553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481893563, states[0] = -95.028120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491595970, states[0] = -6.906750, states[40]= 0.003406
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.940948
 - CaMKt in component CaMK (millimolar): 0.013015
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.632081
 - nass in component intracellular_ions (millimolar): 6.632180
 - ki in component intracellular_ions (millimolar): 145.245830
 - kss in component intracellular_ions (millimolar): 145.245807
 - cansr in component intracellular_ions (millimolar): 1.681854
 - cajsr in component intracellular_ions (millimolar): 1.639943
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003604
 - hf in component INa (dimensionless): 0.880677
 - hs in component INa (dimensionless): 0.880670
 - j in component INa (dimensionless): 0.880621
 - hsp in component INa (dimensionless): 0.727089
 - jp in component INa (dimensionless): 0.880588
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.707735
 - hLp in component INaL (dimensionless): 0.444265
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.609429
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.680525
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.914712
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999827
 - jca in component ICaL (dimensionless): 0.999971
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003131
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.365522
 - xs1 in component IKs (dimensionless): 0.271016
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997327
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:53:15 (234715): called boinc_finish(0)

</stderr_txt>
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