𝕏

Task 55285984

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_883_0
Workunit 26252119
Created 29 Jun 2024, 9:21:21 UTC
Sent 29 Jun 2024, 14:02:46 UTC
Report deadline 2 Jul 2024, 23:38:46 UTC
Received 2 Jul 2024, 22:54:42 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213933
Run time 2 hours 58 min 27 sec
CPU time 2 hours 4 min 7 sec
Validate state Valid
Credit 61.75
Device peak FLOPS 3.66 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.36 MB
Peak swap size 5.43 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_883.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_883_0_r2066726089_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_883_0_r2066726089_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 114.252856
     * GNaL_b in INaL: 0.004807
     * Gto_b in Ito: 0.094810
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033163
     * GKs_b in IKs: 0.002113
     * GK1_b in IK1: 0.148394
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 72.353130
     * GKb_b in IKb: 0.003691
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.052387
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12929009, states[0] = -95.068884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27742423, states[0] = -94.905313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42612932, states[0] = -39.463576, states[40]= 0.000126
Saving checkpoint... 
Iteration: 57531690, states[0] = 16.605899, states[40]= 0.005736
Saving checkpoint... 
Iteration: 72452219, states[0] = -94.976628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87389630, states[0] = -94.955185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97580842, states[0] = -6.340330, states[40]= 0.003096
Saving checkpoint... 
Iteration: 100127238, states[0] = -52.822480, states[40]= 0.000016
Saving checkpoint... 
Iteration: 108974949, states[0] = -94.969259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116440738, states[0] = -94.962274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127807416, states[0] = -94.906566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136340732, states[0] = -94.926584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146848489, states[0] = -94.929840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157845694, states[0] = -94.927951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168241571, states[0] = -94.835377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178186795, states[0] = -94.731224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189114681, states[0] = -39.089673, states[40]= 0.000133
Saving checkpoint... 
Iteration: 202679161, states[0] = -94.705378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216252820, states[0] = -94.849948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229816828, states[0] = -94.910042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243170715, states[0] = -94.593084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256226609, states[0] = -94.811074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269449294, states[0] = -94.959441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282744021, states[0] = -94.837858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293378932, states[0] = -94.940806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301901469, states[0] = -94.948151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315554296, states[0] = 8.449760, states[40]= 0.004788
Saving checkpoint... 
Iteration: 330343042, states[0] = -94.925204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342401084, states[0] = -94.948000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356100786, states[0] = -25.046324, states[40]= 0.000651
Saving checkpoint... 
Iteration: 370073219, states[0] = -0.799561, states[40]= 0.004092
Saving checkpoint... 
Iteration: 382320885, states[0] = -94.912441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395968687, states[0] = -94.962599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408568563, states[0] = 1.831315, states[40]= 0.004404
Saving checkpoint... 
Iteration: 421687190, states[0] = -94.731335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435265410, states[0] = -94.864749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447830075, states[0] = -94.918016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460454041, states[0] = -94.960135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473477237, states[0] = -94.963813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485898897, states[0] = -94.947255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499778305, states[0] = -94.878319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513706453, states[0] = -94.773583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526863143, states[0] = -94.934449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538932066, states[0] = -94.955749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553500564, states[0] = 25.146221, states[40]= 0.000925
Saving checkpoint... 
Iteration: 568102644, states[0] = -26.907920, states[40]= 0.000564
Saving checkpoint... 
Iteration: 581056158, states[0] = 7.664810, states[40]= 0.004760
Saving checkpoint... 
Iteration: 592817818, states[0] = -94.910314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607550925, states[0] = 9.832452, states[40]= 0.004838
Saving checkpoint... 
Iteration: 622056365, states[0] = 7.576468, states[40]= 0.004757
Saving checkpoint... 
Iteration: 634126594, states[0] = -51.687574, states[40]= 0.000019
Saving checkpoint... 
Iteration: 647002262, states[0] = 42.574402, states[40]= 0.094387
Saving checkpoint... 
Iteration: 658750857, states[0] = -94.846883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671564639, states[0] = 3.821487, states[40]= 0.004569
Saving checkpoint... 
Iteration: 685487193, states[0] = -94.965024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697074088, states[0] = -1.331843, states[40]= 0.004015
Saving checkpoint... 
Iteration: 711541442, states[0] = 13.500327, states[40]= 0.005072
Saving checkpoint... 
Iteration: 724085955, states[0] = -10.429309, states[40]= 0.002238
Saving checkpoint... 
Iteration: 736855795, states[0] = -94.931099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748856691, states[0] = -94.931496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761027867, states[0] = 18.015043, states[40]= 0.006312
Saving checkpoint... 
Iteration: 773538892, states[0] = 14.433123, states[40]= 0.005186
Saving checkpoint... 
Iteration: 787082369, states[0] = -7.294439, states[40]= 0.002890
Saving checkpoint... 
Iteration: 799775367, states[0] = -94.875186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813118398, states[0] = -42.918610, states[40]= 0.000076
Saving checkpoint... 
Iteration: 825704044, states[0] = -94.768481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837538959, states[0] = 14.408980, states[40]= 0.005183
Saving checkpoint... 
Iteration: 852078732, states[0] = -4.459467, states[40]= 0.003473
Saving checkpoint... 
Iteration: 865773998, states[0] = -94.873741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878294831, states[0] = -94.893069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890905828, states[0] = -94.949010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904461762, states[0] = -94.961174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917736797, states[0] = -94.826858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929837468, states[0] = -94.921873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943199546, states[0] = -94.759002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955511328, states[0] = 21.302520, states[40]= 0.039802
Saving checkpoint... 
Iteration: 968483352, states[0] = -94.964342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982083046, states[0] = -7.861551, states[40]= 0.002770
Saving checkpoint... 
Iteration: 993776314, states[0] = -94.876021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004332625, states[0] = -94.919134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017245557, states[0] = -94.839505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030239818, states[0] = -94.831299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041555030, states[0] = 8.142591, states[40]= 0.004778
Saving checkpoint... 
Iteration: 1052518999, states[0] = 20.073768, states[40]= 0.010655
Saving checkpoint... 
Iteration: 1067364123, states[0] = -94.934519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081331257, states[0] = -94.918302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093414551, states[0] = -94.951232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106074469, states[0] = -1.569903, states[40]= 0.003979
Saving checkpoint... 
Iteration: 1118457875, states[0] = -94.960387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132081922, states[0] = -6.926463, states[40]= 0.002968
Saving checkpoint... 
Iteration: 1146608492, states[0] = -32.779581, states[40]= 0.000311
Saving checkpoint... 
Iteration: 1160404590, states[0] = -94.948490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172709372, states[0] = -94.778979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185414080, states[0] = -94.951052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199477813, states[0] = -94.963436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213813244, states[0] = -94.906834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226392733, states[0] = -94.944884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239340423, states[0] = -94.923258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253188700, states[0] = -94.734522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266741634, states[0] = -94.833796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278335754, states[0] = -94.920715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292014607, states[0] = 20.771539, states[40]= 0.020120
Saving checkpoint... 
Iteration: 1304972640, states[0] = -94.962622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318550389, states[0] = 10.048256, states[40]= 0.004847
Saving checkpoint... 
Iteration: 1332128689, states[0] = -53.963903, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1345550960, states[0] = 9.818502, states[40]= 0.004838
Saving checkpoint... 
Iteration: 1357320562, states[0] = -94.911616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370030278, states[0] = 17.311704, states[40]= 0.005926
Saving checkpoint... 
Iteration: 1384091253, states[0] = -15.508053, states[40]= 0.001386
Saving checkpoint... 
Iteration: 1398155995, states[0] = -89.517407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412307829, states[0] = -94.902865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426277622, states[0] = -94.877055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439147514, states[0] = -77.054923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452306113, states[0] = -94.901577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462185928, states[0] = -94.727419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475309031, states[0] = -94.903696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488855685, states[0] = -94.930574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501992511, states[0] = -95.081783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1514776365, states[0] = -13.999542, states[40]= 0.001790
Saving checkpoint... 
Iteration: 1527488103, states[0] = -95.108959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1540040374, states[0] = -93.882113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1553007127, states[0] = -95.167665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1566002147, states[0] = 44.499653, states[40]= 0.068900
Saving checkpoint... 
Iteration: 1579353350, states[0] = -95.030395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1593314379, states[0] = 21.193643, states[40]= 0.022710
Saving checkpoint... 
Iteration: 1607715352, states[0] = 20.932555, states[40]= 0.019326
Saving checkpoint... 
Iteration: 1621522411, states[0] = 18.856732, states[40]= 0.009266
Saving checkpoint... 
Iteration: 1634000236, states[0] = -95.170485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647867036, states[0] = -95.261428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660538928, states[0] = 11.833239, states[40]= 0.005992
Saving checkpoint... 
Iteration: 1672425272, states[0] = -95.213326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1684542287, states[0] = 10.130876, states[40]= 0.005777
Saving checkpoint... 
Iteration: 1697449750, states[0] = 6.061937, states[40]= 0.005393
Saving checkpoint... 
Iteration: 1710488512, states[0] = -95.147421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1721165162, states[0] = -4.659547, states[40]= 0.003857
Saving checkpoint... 
Iteration: 1731647672, states[0] = 7.237321, states[40]= 0.005496
Saving checkpoint... 
Iteration: 1744689534, states[0] = -95.149679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1757610719, states[0] = -95.190579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770684658, states[0] = -26.071170, states[40]= 0.000613
Saving checkpoint... 
Iteration: 1785097510, states[0] = -41.002811, states[40]= 0.000104
Saving checkpoint... 
Iteration: 1799425194, states[0] = 17.857009, states[40]= 0.008066
Saving checkpoint... 
Iteration: 1814096428, states[0] = -23.584376, states[40]= 0.000729
Saving checkpoint... 
Iteration: 1828400914, states[0] = -94.984175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1841830635, states[0] = -94.942498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1855246219, states[0] = -94.856903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1868469100, states[0] = -94.972922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1881930343, states[0] = -94.961986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895096582, states[0] = -21.082230, states[40]= 0.000862
Saving checkpoint... 
Iteration: 1907242278, states[0] = -94.837881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919347552, states[0] = -94.928881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933341882, states[0] = -94.925165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946521464, states[0] = 19.584400, states[40]= 0.008549
Saving checkpoint... 
Iteration: 1960060927, states[0] = 5.553291, states[40]= 0.004671
Saving checkpoint... 
Iteration: 1974066146, states[0] = 3.067598, states[40]= 0.004513
Saving checkpoint... 
Iteration: 1987242082, states[0] = -94.834267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001201598, states[0] = -94.762829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013210025, states[0] = -94.779829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2026177195, states[0] = -94.692474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039071609, states[0] = 0.148672, states[40]= 0.004218
Saving checkpoint... 
Iteration: 2052799275, states[0] = -94.895937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067020777, states[0] = 19.734300, states[40]= 0.009019
Saving checkpoint... 
Iteration: 2080959786, states[0] = -94.960071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2094529014, states[0] = 17.687195, states[40]= 0.006113
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.841514
 - CaMKt in component CaMK (millimolar): 0.006768
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.521247
 - nass in component intracellular_ions (millimolar): 6.521306
 - ki in component intracellular_ions (millimolar): 145.459306
 - kss in component intracellular_ions (millimolar): 145.459286
 - cansr in component intracellular_ions (millimolar): 1.298251
 - cajsr in component intracellular_ions (millimolar): 1.260902
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003641
 - hf in component INa (dimensionless): 0.878950
 - hs in component INa (dimensionless): 0.878945
 - j in component INa (dimensionless): 0.878917
 - hsp in component INa (dimensionless): 0.723853
 - jp in component INa (dimensionless): 0.878897
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709443
 - hLp in component INaL (dimensionless): 0.453512
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.626831
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.702987
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.941301
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999904
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001543
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.322186
 - xs1 in component IKs (dimensionless): 0.230454
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997353
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:54:09 (11008): called boinc_finish(0)

</stderr_txt>
]]>


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