𝕏

Task 55285983

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_83_1
Workunit 26252118
Created 29 Jun 2024, 9:21:21 UTC
Sent 29 Jun 2024, 14:02:46 UTC
Report deadline 2 Jul 2024, 23:38:46 UTC
Received 2 Jul 2024, 22:18:37 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213933
Run time 2 hours 55 min 51 sec
CPU time 2 hours 7 min 55 sec
Validate state Valid
Credit 61.69
Device peak FLOPS 3.66 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.30 MB
Peak swap size 5.43 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_83.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_83_1_r1091284480_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_83_1_r1091284480_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 90.524296
     * GNaL_b in INaL: 0.006621
     * Gto_b in Ito: 0.084830
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033496
     * GKs_b in IKs: 0.001980
     * GK1_b in IK1: 0.152713
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 75.279395
     * GKb_b in IKb: 0.003910
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.048406
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11215363, states[0] = -95.012340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24731923, states[0] = -94.977503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39218209, states[0] = -94.920143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53809943, states[0] = -95.006871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67408550, states[0] = -95.040068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82378891, states[0] = -95.022847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97104559, states[0] = -23.616686, states[40]= 0.000747
Saving checkpoint... 
Iteration: 111960239, states[0] = -95.035218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126867910, states[0] = -95.008607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140892452, states[0] = -95.016141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155546359, states[0] = 13.255342, states[40]= 0.004937
Saving checkpoint... 
Iteration: 169762270, states[0] = -94.931378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184260628, states[0] = -94.929114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199065856, states[0] = 5.317723, states[40]= 0.004652
Saving checkpoint... 
Iteration: 213369055, states[0] = -95.005748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227141170, states[0] = -61.164722, states[40]= 0.000004
Saving checkpoint... 
Iteration: 241119652, states[0] = -37.769077, states[40]= 0.000171
Saving checkpoint... 
Iteration: 255173571, states[0] = -94.605258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269886680, states[0] = -95.011923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284812179, states[0] = -94.975369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299441761, states[0] = -95.026236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314228218, states[0] = -94.883381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329076283, states[0] = 0.066074, states[40]= 0.004185
Saving checkpoint... 
Iteration: 343897752, states[0] = -95.015352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358502643, states[0] = 38.143250, states[40]= 0.123571
Saving checkpoint... 
Iteration: 373282315, states[0] = -94.951151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388155588, states[0] = -81.333280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403110710, states[0] = -29.066584, states[40]= 0.000493
Saving checkpoint... 
Iteration: 417685362, states[0] = -94.795871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432397431, states[0] = -95.015195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445281255, states[0] = -94.950105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460005235, states[0] = 27.101879, states[40]= 0.139914
Saving checkpoint... 
Iteration: 474884899, states[0] = -95.011147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489815324, states[0] = -94.977353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504724383, states[0] = -94.876906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519619585, states[0] = -37.696179, states[40]= 0.000173
Saving checkpoint... 
Iteration: 532194500, states[0] = -94.819826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534366743, states[0] = -95.004361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542217317, states[0] = -94.864602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549531083, states[0] = 18.563219, states[40]= 0.005794
Saving checkpoint... 
Iteration: 561111632, states[0] = -29.951378, states[40]= 0.000452
Saving checkpoint... 
Iteration: 569723847, states[0] = -94.875961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579969090, states[0] = -95.030823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591818723, states[0] = -94.979530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601505192, states[0] = 27.196314, states[40]= 0.140709
Saving checkpoint... 
Iteration: 611681027, states[0] = -94.772926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622291718, states[0] = -94.959398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635877415, states[0] = -95.008406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649456273, states[0] = -95.028691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663086559, states[0] = -6.785335, states[40]= 0.002967
Saving checkpoint... 
Iteration: 676417626, states[0] = -95.020596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689486833, states[0] = -95.033253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703198823, states[0] = -94.828854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715931629, states[0] = -95.023845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726933289, states[0] = -95.024198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735186784, states[0] = -94.800467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748921737, states[0] = -95.021557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763357395, states[0] = -95.000257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775452147, states[0] = -95.027885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789345996, states[0] = -94.994898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803007182, states[0] = 24.353291, states[40]= 0.097641
Saving checkpoint... 
Iteration: 815435805, states[0] = -95.024678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829272235, states[0] = -94.940905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841361121, states[0] = -95.001830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854574917, states[0] = 0.827512, states[40]= 0.004278
Saving checkpoint... 
Iteration: 868484490, states[0] = -95.032836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880845971, states[0] = -94.994828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893381642, states[0] = -95.009761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906649605, states[0] = -71.957848, states[40]= 0.000001
Saving checkpoint... 
Iteration: 919043521, states[0] = 14.331116, states[40]= 0.005004
Saving checkpoint... 
Iteration: 932369225, states[0] = -95.005107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946258642, states[0] = -94.925651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960057298, states[0] = 9.004793, states[40]= 0.004797
Saving checkpoint... 
Iteration: 971658846, states[0] = -86.552329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985943507, states[0] = -95.026133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000893814, states[0] = -95.013729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013272009, states[0] = -94.940555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025539564, states[0] = 15.759441, states[40]= 0.005147
Saving checkpoint... 
Iteration: 1039941819, states[0] = -95.025767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054591489, states[0] = -10.915108, states[40]= 0.002115
Saving checkpoint... 
Iteration: 1066591426, states[0] = -10.859261, states[40]= 0.002126
Saving checkpoint... 
Iteration: 1078825983, states[0] = -94.983767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091205630, states[0] = -94.842301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104107084, states[0] = -25.598733, states[40]= 0.000656
Saving checkpoint... 
Iteration: 1117891250, states[0] = -95.012845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129659868, states[0] = -87.999486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144140576, states[0] = -60.455453, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1156944334, states[0] = -95.026188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169799218, states[0] = -94.965204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181898075, states[0] = -95.014922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193833439, states[0] = -94.988029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206683096, states[0] = -94.785581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220262439, states[0] = -94.929937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232665675, states[0] = -93.100993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246530649, states[0] = 18.694030, states[40]= 0.005847
Saving checkpoint... 
Iteration: 1258848697, states[0] = -94.995925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270369683, states[0] = -95.005077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284836006, states[0] = -94.989392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298922072, states[0] = -95.021296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311490973, states[0] = -95.033390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323617373, states[0] = -35.512830, states[40]= 0.000233
Saving checkpoint... 
Iteration: 1337558153, states[0] = 8.653966, states[40]= 0.004787
Saving checkpoint... 
Iteration: 1351058272, states[0] = 8.604884, states[40]= 0.004785
Saving checkpoint... 
Iteration: 1362933738, states[0] = -95.023899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376045046, states[0] = 13.766826, states[40]= 0.004965
Saving checkpoint... 
Iteration: 1388902928, states[0] = -95.016218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401531734, states[0] = 18.364571, states[40]= 0.005719
Saving checkpoint... 
Iteration: 1415144094, states[0] = -64.669571, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1427095803, states[0] = -14.867307, states[40]= 0.001457
Saving checkpoint... 
Iteration: 1438046769, states[0] = 13.122045, states[40]= 0.004929
Saving checkpoint... 
Iteration: 1450773017, states[0] = -94.941328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463457437, states[0] = -95.028386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475234563, states[0] = -94.892641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485361063, states[0] = -95.001405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500098804, states[0] = -22.376780, states[40]= 0.000789
Saving checkpoint... 
Iteration: 1514070930, states[0] = -95.268433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526082920, states[0] = -95.293340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1538988204, states[0] = -95.309427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551369338, states[0] = -4.761444, states[40]= 0.003817
Saving checkpoint... 
Iteration: 1564369925, states[0] = -95.147600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579193566, states[0] = -95.330852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592525760, states[0] = -70.400278, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1604822972, states[0] = -66.441349, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1617662517, states[0] = 0.050036, states[40]= 0.004727
Saving checkpoint... 
Iteration: 1631416641, states[0] = 21.716689, states[40]= 0.015368
Saving checkpoint... 
Iteration: 1645801288, states[0] = 46.699113, states[40]= 0.038824
Saving checkpoint... 
Iteration: 1658347074, states[0] = -95.295513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1671003391, states[0] = 34.623335, states[40]= 0.121068
Saving checkpoint... 
Iteration: 1684538704, states[0] = 13.262330, states[40]= 0.006022
Saving checkpoint... 
Iteration: 1698147982, states[0] = -94.827370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1709819922, states[0] = -62.452081, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1723406944, states[0] = -95.238570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1736026750, states[0] = -95.270063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1749230193, states[0] = -95.274859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1763286391, states[0] = -95.197780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776340847, states[0] = 12.227254, states[40]= 0.005890
Saving checkpoint... 
Iteration: 1788582549, states[0] = -95.329070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1800639574, states[0] = -66.251838, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1814553236, states[0] = 9.821731, states[40]= 0.004865
Saving checkpoint... 
Iteration: 1828677436, states[0] = -94.787507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1842571426, states[0] = 2.153131, states[40]= 0.004436
Saving checkpoint... 
Iteration: 1856569542, states[0] = 3.279170, states[40]= 0.004527
Saving checkpoint... 
Iteration: 1869437050, states[0] = -95.034221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882784856, states[0] = -94.959229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892727879, states[0] = -94.886803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905478354, states[0] = -95.034662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919018116, states[0] = 21.639541, states[40]= 0.011455
Saving checkpoint... 
Iteration: 1931911300, states[0] = -95.019648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944680860, states[0] = -94.772110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1957257816, states[0] = -94.924687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970129123, states[0] = -47.632304, states[40]= 0.000039
Saving checkpoint... 
Iteration: 1983188969, states[0] = -94.806194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1996142999, states[0] = -63.347451, states[40]= 0.000003
Saving checkpoint... 
Iteration: 2009294857, states[0] = -94.961255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023105275, states[0] = -23.878126, states[40]= 0.000735
Saving checkpoint... 
Iteration: 2037790068, states[0] = -94.957105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051691204, states[0] = -94.811415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2064089401, states[0] = -9.103892, states[40]= 0.002478
Saving checkpoint... 
Iteration: 2077517556, states[0] = 21.746412, states[40]= 0.012272
Saving checkpoint... 
Iteration: 2090364256, states[0] = -95.002330, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.909800
 - CaMKt in component CaMK (millimolar): 0.006812
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.425258
 - nass in component intracellular_ions (millimolar): 6.425317
 - ki in component intracellular_ions (millimolar): 145.555567
 - kss in component intracellular_ions (millimolar): 145.555547
 - cansr in component intracellular_ions (millimolar): 1.297305
 - cajsr in component intracellular_ions (millimolar): 1.259374
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003616
 - hf in component INa (dimensionless): 0.880139
 - hs in component INa (dimensionless): 0.880134
 - j in component INa (dimensionless): 0.880106
 - hsp in component INa (dimensionless): 0.726091
 - jp in component INa (dimensionless): 0.880087
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710002
 - hLp in component INaL (dimensionless): 0.451804
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620852
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695591
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934667
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001543
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.324314
 - xs1 in component IKs (dimensionless): 0.243159
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:18:00 (15172): called boinc_finish(0)

</stderr_txt>
]]>


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