𝕏

Task 55285843

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pieske_500-conf_682_1
Workunit 26252048
Created 29 Jun 2024, 9:21:16 UTC
Sent 29 Jun 2024, 14:02:29 UTC
Report deadline 2 Jul 2024, 14:02:29 UTC
Received 30 Jun 2024, 1:20:51 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238165
Run time 2 hours 35 min 34 sec
CPU time 2 hours 31 min 32 sec
Validate state Valid
Credit 40.73
Device peak FLOPS 2.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
aarch64-unknown-linux-gnu
Peak working set size 2.13 MB
Peak swap size 10.95 MB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pieske_500-conf_682.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pieske_500-conf_682_1_r558082361_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pieske_500-conf_682_1_r558082361_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 94.431715
     * GNaL_b in INaL: 0.006554
     * Gto_b in Ito: 0.075694
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.029830
     * GKs_b in IKs: 0.002119
     * GK1_b in IK1: 0.160027
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 73.433859
     * GKb_b in IKb: 0.003869
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025547
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9902846, states[0] = -87.208287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19780929, states[0] = 16.643949, states[40]= 0.006838
Saving checkpoint... 
Iteration: 29781717, states[0] = 16.450338, states[40]= 0.006725
Saving checkpoint... 
Iteration: 39817649, states[0] = -7.032542, states[40]= 0.003472
Saving checkpoint... 
Iteration: 49890656, states[0] = -86.832275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59901076, states[0] = -87.089383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69929845, states[0] = -87.179324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79794268, states[0] = 10.131808, states[40]= 0.005935
Saving checkpoint... 
Iteration: 89679128, states[0] = -87.172586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99602993, states[0] = -46.276391, states[40]= 0.000052
Saving checkpoint... 
Iteration: 109550436, states[0] = 6.559615, states[40]= 0.005670
Saving checkpoint... 
Iteration: 119578363, states[0] = -18.040920, states[40]= 0.001277
Saving checkpoint... 
Iteration: 129557433, states[0] = 2.033962, states[40]= 0.005236
Saving checkpoint... 
Iteration: 139585629, states[0] = -26.363243, states[40]= 0.000640
Saving checkpoint... 
Iteration: 149486216, states[0] = -87.276059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159366517, states[0] = -62.948718, states[40]= 0.000004
Saving checkpoint... 
Iteration: 169233123, states[0] = -87.271441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179173458, states[0] = -87.152989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189197137, states[0] = -87.209000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199260495, states[0] = 24.412624, states[40]= 0.040335
Saving checkpoint... 
Iteration: 209172762, states[0] = -87.150951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219189031, states[0] = -87.191135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229034490, states[0] = 15.456027, states[40]= 0.006479
Saving checkpoint... 
Iteration: 238889109, states[0] = -86.570071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248785120, states[0] = 15.136974, states[40]= 0.006431
Saving checkpoint... 
Iteration: 258780705, states[0] = 17.309479, states[40]= 0.006840
Saving checkpoint... 
Iteration: 268841023, states[0] = -32.449858, states[40]= 0.000352
Saving checkpoint... 
Iteration: 278943610, states[0] = -87.201218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289081858, states[0] = -22.007822, states[40]= 0.000907
Saving checkpoint... 
Iteration: 299195029, states[0] = -87.204256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309271301, states[0] = 21.289924, states[40]= 0.009272
Saving checkpoint... 
Iteration: 319372083, states[0] = -70.923530, states[40]= 0.000001
Saving checkpoint... 
Iteration: 329593283, states[0] = -35.001081, states[40]= 0.000259
Saving checkpoint... 
Iteration: 339760373, states[0] = 24.447844, states[40]= 0.041399
Saving checkpoint... 
Iteration: 349970678, states[0] = -87.252150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360207639, states[0] = -87.229453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370344734, states[0] = -36.639867, states[40]= 0.000209
Saving checkpoint... 
Iteration: 380487927, states[0] = -87.277462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390503082, states[0] = 33.393576, states[40]= 0.125992
Saving checkpoint... 
Iteration: 400570195, states[0] = -8.836151, states[40]= 0.003016
Saving checkpoint... 
Iteration: 410803679, states[0] = 4.564194, states[40]= 0.005503
Saving checkpoint... 
Iteration: 421143212, states[0] = -86.914240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431382748, states[0] = -84.376959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441597717, states[0] = -40.023928, states[40]= 0.000132
Saving checkpoint... 
Iteration: 451706022, states[0] = -87.226314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461879920, states[0] = -81.953965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471993012, states[0] = -87.283952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482195251, states[0] = -87.204548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492484602, states[0] = -87.272843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502727420, states[0] = -87.262496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512875478, states[0] = -76.090565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523117057, states[0] = -63.658336, states[40]= 0.000003
Saving checkpoint... 
Iteration: 533195890, states[0] = -87.205859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543322758, states[0] = -11.595149, states[40]= 0.002370
Saving checkpoint... 
Iteration: 553431941, states[0] = -87.173992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563603635, states[0] = -46.875525, states[40]= 0.000048
Saving checkpoint... 
Iteration: 573830611, states[0] = -20.570585, states[40]= 0.001021
Saving checkpoint... 
Iteration: 583965385, states[0] = -87.243108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594127258, states[0] = -78.666382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604263314, states[0] = 23.694334, states[40]= 0.023103
Saving checkpoint... 
Iteration: 614436859, states[0] = -87.185679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624660240, states[0] = -87.114377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634935800, states[0] = -87.183178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645172245, states[0] = -87.149052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655449702, states[0] = -87.213669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665643160, states[0] = -86.911560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675896881, states[0] = -87.022938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686135091, states[0] = -85.583593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696240245, states[0] = -87.280201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706363746, states[0] = -59.258171, states[40]= 0.000007
Saving checkpoint... 
Iteration: 716680109, states[0] = -87.169310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726962447, states[0] = -87.237847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737301328, states[0] = 6.047044, states[40]= 0.005629
Saving checkpoint... 
Iteration: 747702961, states[0] = -87.220104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757994456, states[0] = -87.285475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768147823, states[0] = -87.038148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778315400, states[0] = -4.184862, states[40]= 0.004144
Saving checkpoint... 
Iteration: 788502394, states[0] = 36.375761, states[40]= 0.108359
Saving checkpoint... 
Iteration: 798700377, states[0] = -87.214900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808870164, states[0] = -68.061228, states[40]= 0.000002
Saving checkpoint... 
Iteration: 819026966, states[0] = 19.014219, states[40]= 0.007398
Saving checkpoint... 
Iteration: 829272743, states[0] = 20.751279, states[40]= 0.008586
Saving checkpoint... 
Iteration: 839600661, states[0] = -43.403159, states[40]= 0.000081
Saving checkpoint... 
Iteration: 849852047, states[0] = -45.013361, states[40]= 0.000063
Saving checkpoint... 
Iteration: 859969122, states[0] = -87.249116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870170504, states[0] = -87.144124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880423038, states[0] = -87.150941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890742694, states[0] = -87.283145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901022020, states[0] = 21.025221, states[40]= 0.008904
Saving checkpoint... 
Iteration: 911301114, states[0] = 6.179341, states[40]= 0.005639
Saving checkpoint... 
Iteration: 921504900, states[0] = 28.402909, states[40]= 0.122689
Saving checkpoint... 
Iteration: 931629564, states[0] = -81.565306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941756503, states[0] = 26.345894, states[40]= 0.094662
Saving checkpoint... 
Iteration: 952122173, states[0] = -71.057824, states[40]= 0.000001
Saving checkpoint... 
Iteration: 962504925, states[0] = 28.358404, states[40]= 0.122326
Saving checkpoint... 
Iteration: 972783708, states[0] = 15.848951, states[40]= 0.006543
Saving checkpoint... 
Iteration: 983016894, states[0] = 22.737274, states[40]= 0.013566
Saving checkpoint... 
Iteration: 993224244, states[0] = -87.257174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003399323, states[0] = -87.056487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013549001, states[0] = 7.463120, states[40]= 0.005736
Saving checkpoint... 
Iteration: 1023684518, states[0] = -87.179759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033915342, states[0] = -87.129484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044297711, states[0] = 8.229103, states[40]= 0.005791
Saving checkpoint... 
Iteration: 1054519711, states[0] = 21.848127, states[40]= 0.010332
Saving checkpoint... 
Iteration: 1064756702, states[0] = 26.175196, states[40]= 0.091047
Saving checkpoint... 
Iteration: 1074898767, states[0] = -87.050218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085137237, states[0] = -86.232085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095367053, states[0] = -63.651511, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1105629727, states[0] = -81.744304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115897181, states[0] = -87.027732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126134035, states[0] = -85.115607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136339522, states[0] = -30.750854, states[40]= 0.000424
Saving checkpoint... 
Iteration: 1146652760, states[0] = -87.083081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156755617, states[0] = 27.304719, states[40]= 0.110897
Saving checkpoint... 
Iteration: 1166861816, states[0] = -56.798703, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1177063988, states[0] = -2.955857, states[40]= 0.004411
Saving checkpoint... 
Iteration: 1187347447, states[0] = -39.715304, states[40]= 0.000137
Saving checkpoint... 
Iteration: 1197513616, states[0] = 23.619208, states[40]= 0.021905
Saving checkpoint... 
Iteration: 1207694090, states[0] = -87.201344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218001089, states[0] = 39.931385, states[40]= 0.037398
Saving checkpoint... 
Iteration: 1228259583, states[0] = 24.689737, states[40]= 0.049114
Saving checkpoint... 
Iteration: 1238444957, states[0] = -87.203181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248558031, states[0] = 1.637861, states[40]= 0.005186
Saving checkpoint... 
Iteration: 1258720871, states[0] = -87.251578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268986604, states[0] = -87.274825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279236626, states[0] = -87.274845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289530622, states[0] = 17.349288, states[40]= 0.006850
Saving checkpoint... 
Iteration: 1299815143, states[0] = -3.956149, states[40]= 0.004195
Saving checkpoint... 
Iteration: 1309946228, states[0] = -87.205818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320126599, states[0] = -77.734636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330246382, states[0] = -87.287277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340384232, states[0] = -85.211190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350637872, states[0] = -86.364929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360945555, states[0] = -87.204340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371136327, states[0] = -85.998200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381291576, states[0] = 11.716774, states[40]= 0.006055
Saving checkpoint... 
Iteration: 1391356868, states[0] = -50.723099, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1401441859, states[0] = -87.196272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411619608, states[0] = -67.250031, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1421849735, states[0] = -42.333752, states[40]= 0.000094
Saving checkpoint... 
Iteration: 1432167619, states[0] = -87.135588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442370013, states[0] = -67.838719, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1452517633, states[0] = 22.516664, states[40]= 0.012486
Saving checkpoint... 
Iteration: 1462692970, states[0] = -87.198658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472844163, states[0] = -35.993245, states[40]= 0.000228
Saving checkpoint... 
Iteration: 1482981744, states[0] = -87.267868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493194444, states[0] = -87.201830, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.167157
 - CaMKt in component CaMK (millimolar): 0.019192
 - cass in component intracellular_ions (millimolar): 0.000094
 - nai in component intracellular_ions (millimolar): 6.653941
 - nass in component intracellular_ions (millimolar): 6.654040
 - ki in component intracellular_ions (millimolar): 145.305758
 - kss in component intracellular_ions (millimolar): 145.305734
 - cansr in component intracellular_ions (millimolar): 1.415954
 - cajsr in component intracellular_ions (millimolar): 1.198607
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.007888
 - hf in component INa (dimensionless): 0.672949
 - hs in component INa (dimensionless): 0.672839
 - j in component INa (dimensionless): 0.672055
 - hsp in component INa (dimensionless): 0.425856
 - jp in component INa (dimensionless): 0.669655
 - mL in component INaL (dimensionless): 0.000215
 - hL in component INaL (dimensionless): 0.374760
 - hLp in component INaL (dimensionless): 0.172477
 - a in component Ito (dimensionless): 0.001050
 - iF in component Ito (dimensionless): 0.999495
 - iS in component Ito (dimensionless): 0.283832
 - ap in component Ito (dimensionless): 0.000535
 - iFp in component Ito (dimensionless): 0.999495
 - iSp in component Ito (dimensionless): 0.327687
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.847879
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.989866
 - jca in component ICaL (dimensionless): 0.990481
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004149
 - xrf in component IKr (dimensionless): 0.002344
 - xrs in component IKr (dimensionless): 0.686930
 - xs1 in component IKs (dimensionless): 0.395828
 - xs2 in component IKs (dimensionless): 0.000222
 - xk1 in component IK1 (dimensionless): 0.996943
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:19:59 (262266): called boinc_finish(0)

</stderr_txt>
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