𝕏

Task 55285673

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_481_1
Workunit 26251963
Created 29 Jun 2024, 9:21:11 UTC
Sent 29 Jun 2024, 14:02:46 UTC
Report deadline 2 Jul 2024, 23:38:46 UTC
Received 2 Jul 2024, 22:23:18 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213933
Run time 2 hours 56 min 22 sec
CPU time 2 hours 7 min 20 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 3.66 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.36 MB
Peak swap size 5.43 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_481.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_481_1_r783682464_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_481_1_r783682464_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 115.022041
     * GNaL_b in INaL: 0.005713
     * Gto_b in Ito: 0.098953
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032573
     * GKs_b in IKs: 0.002052
     * GK1_b in IK1: 0.170179
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 74.740461
     * GKb_b in IKb: 0.003728
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038677
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13426174, states[0] = -95.236006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28384377, states[0] = -95.182250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43037956, states[0] = 15.065323, states[40]= 0.005100
Saving checkpoint... 
Iteration: 57898936, states[0] = -95.150679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72753228, states[0] = -95.051624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86798553, states[0] = -95.089711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101469576, states[0] = -95.148957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115802686, states[0] = -95.087327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130351389, states[0] = -95.113745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145208642, states[0] = -94.971623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159557491, states[0] = 8.418193, states[40]= 0.004717
Saving checkpoint... 
Iteration: 173290333, states[0] = -95.074690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187345244, states[0] = -95.108883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201339699, states[0] = -95.106028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216157146, states[0] = -87.812086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231131482, states[0] = -51.387672, states[40]= 0.000022
Saving checkpoint... 
Iteration: 245662736, states[0] = -93.306504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260511136, states[0] = 21.278469, states[40]= 0.041506
Saving checkpoint... 
Iteration: 275381914, states[0] = -95.123055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290237725, states[0] = -95.017097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304834108, states[0] = -95.102816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319587229, states[0] = -7.993958, states[40]= 0.002710
Saving checkpoint... 
Iteration: 334484448, states[0] = -95.145031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349366549, states[0] = -95.117459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364053455, states[0] = 10.025447, states[40]= 0.004754
Saving checkpoint... 
Iteration: 378728605, states[0] = -95.003640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391606305, states[0] = -25.768011, states[40]= 0.000648
Saving checkpoint... 
Iteration: 406332071, states[0] = -95.101651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421156509, states[0] = -86.775925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436044408, states[0] = 13.368932, states[40]= 0.004877
Saving checkpoint... 
Iteration: 450967243, states[0] = -95.142551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465851801, states[0] = -95.111267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478674779, states[0] = -94.868769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480782504, states[0] = -95.067171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488094528, states[0] = -14.494972, states[40]= 0.001511
Saving checkpoint... 
Iteration: 495560908, states[0] = 7.035809, states[40]= 0.004678
Saving checkpoint... 
Iteration: 507141536, states[0] = -63.095514, states[40]= 0.000003
Saving checkpoint... 
Iteration: 515760074, states[0] = -95.044884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525769159, states[0] = -95.054519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537725817, states[0] = -94.999192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547662177, states[0] = -93.011194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558113657, states[0] = -32.876302, states[40]= 0.000328
Saving checkpoint... 
Iteration: 568552360, states[0] = 10.444686, states[40]= 0.004763
Saving checkpoint... 
Iteration: 582011219, states[0] = 21.265462, states[40]= 0.040708
Saving checkpoint... 
Iteration: 595582764, states[0] = -4.569707, states[40]= 0.003415
Saving checkpoint... 
Iteration: 609134548, states[0] = -54.826557, states[40]= 0.000012
Saving checkpoint... 
Iteration: 622477602, states[0] = -95.143926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635459521, states[0] = -95.141220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649154231, states[0] = -82.769150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661985153, states[0] = -95.144898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673321470, states[0] = -95.095465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681296454, states[0] = -95.078514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695123420, states[0] = -42.668503, states[40]= 0.000085
Saving checkpoint... 
Iteration: 709570634, states[0] = 2.607073, states[40]= 0.004429
Saving checkpoint... 
Iteration: 721787036, states[0] = -95.070918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735816372, states[0] = -95.092303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749341033, states[0] = -95.106036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761866605, states[0] = -95.117201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775774010, states[0] = -95.059141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787758617, states[0] = -95.043069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800733443, states[0] = -95.010605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814824327, states[0] = -95.097051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827237350, states[0] = -95.016190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839765968, states[0] = -95.051025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852968940, states[0] = -95.142537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865392941, states[0] = -95.126126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878577369, states[0] = -1.055371, states[40]= 0.004015
Saving checkpoint... 
Iteration: 892494472, states[0] = -95.145881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906448461, states[0] = -95.139150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918034692, states[0] = 16.628260, states[40]= 0.005309
Saving checkpoint... 
Iteration: 932307515, states[0] = -95.086362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947435643, states[0] = -95.136677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959722566, states[0] = -94.993696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972308889, states[0] = -95.087271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986480564, states[0] = -95.144083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001418069, states[0] = -95.132778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013388691, states[0] = -95.124723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025483443, states[0] = -95.144435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038050170, states[0] = 11.270334, states[40]= 0.004785
Saving checkpoint... 
Iteration: 1050886185, states[0] = -95.123903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064440473, states[0] = -95.137555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076280565, states[0] = -95.065044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090736384, states[0] = -95.014649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103464271, states[0] = -95.141661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116085622, states[0] = -6.704483, states[40]= 0.002981
Saving checkpoint... 
Iteration: 1128131645, states[0] = -51.559255, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1140090293, states[0] = -10.611877, states[40]= 0.002175
Saving checkpoint... 
Iteration: 1153007027, states[0] = 23.060060, states[40]= 0.109534
Saving checkpoint... 
Iteration: 1166482290, states[0] = -95.144191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178870096, states[0] = -95.118247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192806466, states[0] = -95.085465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205209994, states[0] = -94.971796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216617987, states[0] = -37.138601, states[40]= 0.000189
Saving checkpoint... 
Iteration: 1230934550, states[0] = -95.136266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244942569, states[0] = -95.137836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257652231, states[0] = -79.108997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269730309, states[0] = -95.005634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283634908, states[0] = -55.235852, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1297091613, states[0] = -11.795540, states[40]= 0.001952
Saving checkpoint... 
Iteration: 1308908623, states[0] = -95.130221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321743548, states[0] = -95.024300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334708344, states[0] = -94.968670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347429034, states[0] = -95.135031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360876025, states[0] = -95.120277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373141024, states[0] = -62.457238, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1384249798, states[0] = -95.032244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396797653, states[0] = -95.078947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409646091, states[0] = -69.163756, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1421670187, states[0] = -94.746986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431698631, states[0] = -94.949859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446331016, states[0] = -95.100385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460328940, states[0] = -95.099236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472410038, states[0] = -95.130478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485651433, states[0] = -77.683452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498048760, states[0] = 11.793503, states[40]= 0.004802
Saving checkpoint... 
Iteration: 1510942911, states[0] = -93.874238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1525720081, states[0] = -95.307821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1538944142, states[0] = -95.349220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551444115, states[0] = -94.777404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564294069, states[0] = -32.080640, states[40]= 0.000356
Saving checkpoint... 
Iteration: 1577928236, states[0] = -95.345546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592307360, states[0] = -95.316931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605085147, states[0] = -22.548230, states[40]= 0.000838
Saving checkpoint... 
Iteration: 1617514547, states[0] = -95.330454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631121714, states[0] = 19.418572, states[40]= 0.009384
Saving checkpoint... 
Iteration: 1644979534, states[0] = -16.390532, states[40]= 0.001430
Saving checkpoint... 
Iteration: 1656722203, states[0] = -67.724956, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1670112726, states[0] = 21.611372, states[40]= 0.030531
Saving checkpoint... 
Iteration: 1682707190, states[0] = 24.143729, states[40]= 0.099751
Saving checkpoint... 
Iteration: 1696174103, states[0] = -95.398279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1710400713, states[0] = -40.133708, states[40]= 0.000126
Saving checkpoint... 
Iteration: 1723281569, states[0] = -18.683262, states[40]= 0.001156
Saving checkpoint... 
Iteration: 1735826765, states[0] = 17.740613, states[40]= 0.007400
Saving checkpoint... 
Iteration: 1747472457, states[0] = -95.397013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1761583446, states[0] = -95.405336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1775684305, states[0] = -95.405939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1789712291, states[0] = -95.328371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803645221, states[0] = -75.112702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1816801662, states[0] = -95.123125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1830114365, states[0] = -35.460499, states[40]= 0.000237
Saving checkpoint... 
Iteration: 1840325897, states[0] = -95.118272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1852871813, states[0] = -95.132704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866236089, states[0] = -95.023415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879254095, states[0] = -95.043589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892156874, states[0] = -87.886869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904291551, states[0] = -95.076817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1917265666, states[0] = -95.051987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1930426518, states[0] = -95.135395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943420452, states[0] = -95.133570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956393247, states[0] = -95.126052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970117831, states[0] = -37.010607, states[40]= 0.000192
Saving checkpoint... 
Iteration: 1984720508, states[0] = -94.989834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998639536, states[0] = -60.656106, states[40]= 0.000005
Saving checkpoint... 
Iteration: 2011112302, states[0] = -31.564402, states[40]= 0.000382
Saving checkpoint... 
Iteration: 2024512258, states[0] = 21.121213, states[40]= 0.032097
Saving checkpoint... 
Iteration: 2037476024, states[0] = -95.142758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050145077, states[0] = -67.740417, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2061208424, states[0] = -94.968296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2074580213, states[0] = -2.829922, states[40]= 0.003735
Saving checkpoint... 
Iteration: 2087603023, states[0] = -22.616772, states[40]= 0.000795
Saving checkpoint... 
Iteration: 2098642166, states[0] = -63.888678, states[40]= 0.000003
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.021528
 - CaMKt in component CaMK (millimolar): 0.007009
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.463802
 - nass in component intracellular_ions (millimolar): 6.463862
 - ki in component intracellular_ions (millimolar): 145.513979
 - kss in component intracellular_ions (millimolar): 145.513959
 - cansr in component intracellular_ions (millimolar): 1.309213
 - cajsr in component intracellular_ions (millimolar): 1.271091
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003575
 - hf in component INa (dimensionless): 0.882062
 - hs in component INa (dimensionless): 0.882058
 - j in component INa (dimensionless): 0.882030
 - hsp in component INa (dimensionless): 0.729727
 - jp in component INa (dimensionless): 0.882012
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.713426
 - hLp in component INaL (dimensionless): 0.456676
 - a in component Ito (dimensionless): 0.000618
 - iF in component Ito (dimensionless): 0.999872
 - iS in component Ito (dimensionless): 0.623181
 - ap in component Ito (dimensionless): 0.000315
 - iFp in component Ito (dimensionless): 0.999872
 - iSp in component Ito (dimensionless): 0.698811
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937440
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999892
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001580
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.324746
 - xs1 in component IKs (dimensionless): 0.240151
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997305
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:22:48 (13584): called boinc_finish(0)

</stderr_txt>
]]>


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