𝕏

Task 55283630

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_365_1
Workunit 26250950
Created 29 Jun 2024, 9:20:04 UTC
Sent 29 Jun 2024, 13:49:47 UTC
Report deadline 2 Jul 2024, 23:25:47 UTC
Received 2 Jul 2024, 3:16:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234386
Run time 2 hours 20 min
CPU time 2 hours 19 min 49 sec
Validate state Valid
Credit 65.77
Device peak FLOPS 4.33 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.92 MB
Peak swap size 3.82 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.16.6</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_365.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_365_1_r699872413_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_365_1_r699872413_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.244144
     * GNaL_b in INaL: 0.005255
     * Gto_b in Ito: 0.083611
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031679
     * GKs_b in IKs: 0.002146
     * GK1_b in IK1: 0.153733
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 68.335693
     * GKb_b in IKb: 0.003885
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025811
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15222927, states[0] = -94.850842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30498254, states[0] = -94.984819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46304546, states[0] = -94.898587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61520860, states[0] = 20.657492, states[40]= 0.008931
Saving checkpoint... 
Iteration: 77085641, states[0] = -8.914324, states[40]= 0.002602
Saving checkpoint... 
Iteration: 92801360, states[0] = -94.876857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108272672, states[0] = -94.847098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123993002, states[0] = -94.945066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139325806, states[0] = -94.889977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154634858, states[0] = -56.688905, states[40]= 0.000009
Saving checkpoint... 
Iteration: 170026611, states[0] = 19.314078, states[40]= 0.006682
Saving checkpoint... 
Iteration: 185359113, states[0] = -94.907165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200741538, states[0] = -94.802800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216741529, states[0] = -94.802671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232584759, states[0] = -7.764089, states[40]= 0.002845
Saving checkpoint... 
Iteration: 248148025, states[0] = -72.318622, states[40]= 0.000001
Saving checkpoint... 
Iteration: 263615343, states[0] = -36.548035, states[40]= 0.000212
Saving checkpoint... 
Iteration: 279124737, states[0] = -45.935984, states[40]= 0.000053
Saving checkpoint... 
Iteration: 294813392, states[0] = -94.879694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310479676, states[0] = -94.940506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325899416, states[0] = -94.922375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341465210, states[0] = -94.938134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356937543, states[0] = -94.932644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373006669, states[0] = 25.411986, states[40]= 0.114404
Saving checkpoint... 
Iteration: 388702296, states[0] = -94.730514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404839367, states[0] = -94.896380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420705286, states[0] = -94.736849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436566430, states[0] = 3.764773, states[40]= 0.004689
Saving checkpoint... 
Iteration: 452187925, states[0] = -94.696950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467586244, states[0] = -9.002926, states[40]= 0.002577
Saving checkpoint... 
Iteration: 483409550, states[0] = -94.925364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499325847, states[0] = -94.888115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514718017, states[0] = -94.762261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530276523, states[0] = -94.846882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546035374, states[0] = 16.522288, states[40]= 0.005557
Saving checkpoint... 
Iteration: 561529201, states[0] = 18.555039, states[40]= 0.006210
Saving checkpoint... 
Iteration: 576944314, states[0] = -94.933967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592802394, states[0] = -94.870969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608150167, states[0] = -75.420661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624010324, states[0] = 23.001418, states[40]= 0.049114
Saving checkpoint... 
Iteration: 639705748, states[0] = -94.737669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655345153, states[0] = -94.899404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671261026, states[0] = -94.828983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687109115, states[0] = -30.545844, states[40]= 0.000442
Saving checkpoint... 
Iteration: 703224484, states[0] = -94.774048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719051004, states[0] = 10.568726, states[40]= 0.005004
Saving checkpoint... 
Iteration: 734802594, states[0] = -94.871036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750927142, states[0] = -94.929920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766679906, states[0] = -94.663079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782098683, states[0] = -20.574366, states[40]= 0.000937
Saving checkpoint... 
Iteration: 798132604, states[0] = -54.198517, states[40]= 0.000014
Saving checkpoint... 
Iteration: 813755573, states[0] = -94.821919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829260750, states[0] = -94.828532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845117752, states[0] = -38.900202, states[40]= 0.000152
Saving checkpoint... 
Iteration: 860738587, states[0] = -94.797534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876489192, states[0] = -94.941488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892403523, states[0] = -94.923279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908113717, states[0] = -34.969503, states[40]= 0.000262
Saving checkpoint... 
Iteration: 924073568, states[0] = -0.023824, states[40]= 0.004300
Saving checkpoint... 
Iteration: 939691818, states[0] = -94.706545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955278379, states[0] = -94.848544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970852443, states[0] = -94.902970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986469278, states[0] = -94.938387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002102239, states[0] = -23.974430, states[40]= 0.000754
Saving checkpoint... 
Iteration: 1017846190, states[0] = -94.899713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033330683, states[0] = -94.890812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048785034, states[0] = -94.855176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064598050, states[0] = -19.967968, states[40]= 0.000978
Saving checkpoint... 
Iteration: 1080600743, states[0] = -22.545019, states[40]= 0.000825
Saving checkpoint... 
Iteration: 1096299103, states[0] = -94.867897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112217402, states[0] = -94.760685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127940914, states[0] = -94.932867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143777306, states[0] = -94.847293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159901388, states[0] = -94.922432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175667783, states[0] = -94.067955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191479295, states[0] = -94.939843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207061323, states[0] = 6.168387, states[40]= 0.004836
Saving checkpoint... 
Iteration: 1222921115, states[0] = -94.928066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238667914, states[0] = -94.089720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254427353, states[0] = -94.929632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269828254, states[0] = -94.889135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285745967, states[0] = -94.808342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301561890, states[0] = 5.910883, states[40]= 0.004823
Saving checkpoint... 
Iteration: 1317423286, states[0] = -94.928565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333086395, states[0] = -9.131577, states[40]= 0.002550
Saving checkpoint... 
Iteration: 1348760458, states[0] = -94.827816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364873111, states[0] = -94.912090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380287958, states[0] = -94.857753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395952440, states[0] = -94.935066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411498103, states[0] = -94.942306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427182242, states[0] = -94.676371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442924560, states[0] = -94.928806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458582270, states[0] = -5.790764, states[40]= 0.003273
Saving checkpoint... 
Iteration: 1474258565, states[0] = -94.825342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490179237, states[0] = -94.657374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505823094, states[0] = -63.921076, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1521384079, states[0] = -20.680454, states[40]= 0.000992
Saving checkpoint... 
Iteration: 1537002076, states[0] = -41.267613, states[40]= 0.000110
Saving checkpoint... 
Iteration: 1552366534, states[0] = -95.023067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568078841, states[0] = -95.217692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1583845892, states[0] = -94.545946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599293438, states[0] = -95.235247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614992595, states[0] = -31.933486, states[40]= 0.000375
Saving checkpoint... 
Iteration: 1630662465, states[0] = -95.024458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1646443954, states[0] = 10.095947, states[40]= 0.005888
Saving checkpoint... 
Iteration: 1662387622, states[0] = -26.529732, states[40]= 0.000631
Saving checkpoint... 
Iteration: 1678401763, states[0] = -95.123828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694036413, states[0] = -95.181103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1709522418, states[0] = -67.529937, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1725208376, states[0] = -95.136673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1740802490, states[0] = -95.125452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1756454559, states[0] = -95.203435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1772097430, states[0] = -95.241441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1788065145, states[0] = -3.187887, states[40]= 0.004267
Saving checkpoint... 
Iteration: 1804254330, states[0] = -94.877379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1819633025, states[0] = -57.587680, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1835468899, states[0] = -94.965358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1851080343, states[0] = -4.982408, states[40]= 0.003455
Saving checkpoint... 
Iteration: 1866581188, states[0] = -5.381213, states[40]= 0.003367
Saving checkpoint... 
Iteration: 1882172759, states[0] = -94.550433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1898493764, states[0] = -94.945742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914612477, states[0] = -33.923179, states[40]= 0.000299
Saving checkpoint... 
Iteration: 1930352570, states[0] = -94.904066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945878330, states[0] = -94.914838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1961749809, states[0] = -94.813992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1977356670, states[0] = -94.904747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993236283, states[0] = -94.793354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009486975, states[0] = -94.940529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2025001382, states[0] = 48.962523, states[40]= 0.055542
Saving checkpoint... 
Iteration: 2041120682, states[0] = -41.812880, states[40]= 0.000100
Saving checkpoint... 
Iteration: 2056998134, states[0] = -94.941858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072870419, states[0] = -94.910459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2089149345, states[0] = -74.199537, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.817907
 - CaMKt in component CaMK (millimolar): 0.007076
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.641601
 - nass in component intracellular_ions (millimolar): 6.641661
 - ki in component intracellular_ions (millimolar): 145.333265
 - kss in component intracellular_ions (millimolar): 145.333246
 - cansr in component intracellular_ions (millimolar): 1.322896
 - cajsr in component intracellular_ions (millimolar): 1.285144
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003649
 - hf in component INa (dimensionless): 0.878537
 - hs in component INa (dimensionless): 0.878532
 - j in component INa (dimensionless): 0.878500
 - hsp in component INa (dimensionless): 0.723075
 - jp in component INa (dimensionless): 0.878479
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.707975
 - hLp in component INaL (dimensionless): 0.450308
 - a in component Ito (dimensionless): 0.000627
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.622921
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.698107
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937586
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999893
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001646
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330415
 - xs1 in component IKs (dimensionless): 0.236009
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997359
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:16:11 (1595426): called boinc_finish(0)

</stderr_txt>
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