𝕏

Task 55283343

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_562_0
Workunit 26250807
Created 29 Jun 2024, 9:19:53 UTC
Sent 29 Jun 2024, 13:47:21 UTC
Report deadline 2 Jul 2024, 23:23:21 UTC
Received 30 Jun 2024, 8:01:07 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228858
Run time 3 hours 12 min 48 sec
CPU time 2 hours 49 min 24 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 5.39 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.70 MB
Peak swap size 5.32 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_562.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_562_0_r350333373_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_562_0_r350333373_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 112.907096
     * GNaL_b in INaL: 0.004785
     * Gto_b in Ito: 0.084005
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032160
     * GKs_b in IKs: 0.001941
     * GK1_b in IK1: 0.175355
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 67.668521
     * GKb_b in IKb: 0.003730
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.021992
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 20435030, states[0] = -95.058635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40960037, states[0] = -95.042780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60627175, states[0] = -52.446758, states[40]= 0.000018
Saving checkpoint... 
Iteration: 81984676, states[0] = -95.031654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103191435, states[0] = -94.825623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124344311, states[0] = -94.990723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144970306, states[0] = -95.024593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163018578, states[0] = 20.933169, states[40]= 0.011557
Saving checkpoint... 
Iteration: 174762513, states[0] = -94.930712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182186941, states[0] = -94.813274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190268826, states[0] = -94.936975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197543725, states[0] = 12.888826, states[40]= 0.005204
Saving checkpoint... 
Iteration: 204402990, states[0] = -95.010200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211701181, states[0] = -94.841540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218187987, states[0] = -94.815230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225689081, states[0] = -94.817476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232404488, states[0] = -95.010491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240357637, states[0] = -94.994820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248644551, states[0] = -73.328498, states[40]= 0.000001
Saving checkpoint... 
Iteration: 257071681, states[0] = 0.152644, states[40]= 0.004325
Saving checkpoint... 
Iteration: 264630929, states[0] = -55.667487, states[40]= 0.000010
Saving checkpoint... 
Iteration: 272809934, states[0] = -94.969834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280543211, states[0] = 13.092900, states[40]= 0.005222
Saving checkpoint... 
Iteration: 287285217, states[0] = -94.951542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294652035, states[0] = -86.578467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302513465, states[0] = 21.988484, states[40]= 0.025404
Saving checkpoint... 
Iteration: 309809217, states[0] = -94.969326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317000059, states[0] = -87.757267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324957305, states[0] = -95.021524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331910363, states[0] = -95.011884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339157456, states[0] = -92.769811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345425270, states[0] = -95.015394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352256590, states[0] = -94.923783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360021225, states[0] = 20.335308, states[40]= 0.009080
Saving checkpoint... 
Iteration: 366447910, states[0] = -95.019884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373431523, states[0] = -95.016715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380283442, states[0] = -94.949976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388190254, states[0] = -94.819699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395534436, states[0] = 16.365301, states[40]= 0.005740
Saving checkpoint... 
Iteration: 403098576, states[0] = -22.393962, states[40]= 0.000814
Saving checkpoint... 
Iteration: 410335702, states[0] = -94.984597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426907400, states[0] = -95.011062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434266370, states[0] = -94.934115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441636424, states[0] = -62.084647, states[40]= 0.000003
Saving checkpoint... 
Iteration: 449483214, states[0] = -95.025221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457223219, states[0] = -94.879396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464894728, states[0] = -95.007548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471004442, states[0] = 30.474467, states[40]= 0.151265
Saving checkpoint... 
Iteration: 477136803, states[0] = -62.549454, states[40]= 0.000003
Saving checkpoint... 
Iteration: 484915116, states[0] = -95.012961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491621450, states[0] = -45.303722, states[40]= 0.000056
Saving checkpoint... 
Iteration: 499021113, states[0] = 20.362239, states[40]= 0.009157
Saving checkpoint... 
Iteration: 506073083, states[0] = -0.670443, states[40]= 0.004211
Saving checkpoint... 
Iteration: 513296343, states[0] = -94.960171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520664686, states[0] = -94.577440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528302552, states[0] = -94.964656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534877074, states[0] = -95.001907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542318025, states[0] = -94.974720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550157674, states[0] = -92.897564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557585574, states[0] = -9.912884, states[40]= 0.002388
Saving checkpoint... 
Iteration: 565033561, states[0] = 16.670285, states[40]= 0.005823
Saving checkpoint... 
Iteration: 573009897, states[0] = 22.988045, states[40]= 0.055293
Saving checkpoint... 
Iteration: 579560365, states[0] = 5.906219, states[40]= 0.004833
Saving checkpoint... 
Iteration: 587088395, states[0] = -12.495668, states[40]= 0.001887
Saving checkpoint... 
Iteration: 594765881, states[0] = -94.933520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601991916, states[0] = -95.026205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609452796, states[0] = -95.020587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615740991, states[0] = -94.904750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622366286, states[0] = -94.997951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629406526, states[0] = -95.010709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637701961, states[0] = -94.842610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645468587, states[0] = -95.023079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653112661, states[0] = -36.281801, states[40]= 0.000209
Saving checkpoint... 
Iteration: 660697400, states[0] = -94.833836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667322068, states[0] = -94.977033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674856683, states[0] = -94.994096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683092932, states[0] = -16.857556, states[40]= 0.001250
Saving checkpoint... 
Iteration: 691280583, states[0] = -94.947319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698143654, states[0] = -71.907948, states[40]= 0.000001
Saving checkpoint... 
Iteration: 704618040, states[0] = -41.737858, states[40]= 0.000096
Saving checkpoint... 
Iteration: 712562150, states[0] = 5.077997, states[40]= 0.004785
Saving checkpoint... 
Iteration: 720754396, states[0] = -94.921077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729386561, states[0] = -95.004909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737966404, states[0] = -95.022696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746561597, states[0] = 5.336984, states[40]= 0.004800
Saving checkpoint... 
Iteration: 754592441, states[0] = -16.378451, states[40]= 0.001306
Saving checkpoint... 
Iteration: 761558462, states[0] = 6.766608, states[40]= 0.004877
Saving checkpoint... 
Iteration: 768969486, states[0] = -95.023135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776975861, states[0] = -95.024037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784545017, states[0] = 12.384698, states[40]= 0.005162
Saving checkpoint... 
Iteration: 792644561, states[0] = -73.337340, states[40]= 0.000001
Saving checkpoint... 
Iteration: 801218752, states[0] = -94.872054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808593269, states[0] = -17.186811, states[40]= 0.001214
Saving checkpoint... 
Iteration: 814930541, states[0] = -95.016236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821595828, states[0] = -19.695696, states[40]= 0.000986
Saving checkpoint... 
Iteration: 829280346, states[0] = -94.947026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842259800, states[0] = -94.927000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861177028, states[0] = -94.788817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880430859, states[0] = -95.016262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897234659, states[0] = -94.896020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917830668, states[0] = -94.981662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938230966, states[0] = -94.890748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958723717, states[0] = -94.879860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979438057, states[0] = -95.017659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998284940, states[0] = -94.950855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018224672, states[0] = -94.881300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038191679, states[0] = -94.822202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056935335, states[0] = -95.017071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077623176, states[0] = -47.142645, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1098530030, states[0] = 17.848853, states[40]= 0.006249
Saving checkpoint... 
Iteration: 1119339499, states[0] = -94.986053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140301929, states[0] = -94.963839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161430749, states[0] = -95.016065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182305446, states[0] = -94.966254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203585752, states[0] = -10.071172, states[40]= 0.002356
Saving checkpoint... 
Iteration: 1223513364, states[0] = 22.010353, states[40]= 0.025917
Saving checkpoint... 
Iteration: 1244477755, states[0] = -95.024008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265381158, states[0] = -95.002833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286399177, states[0] = -95.008313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307454274, states[0] = -95.020408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328569562, states[0] = 1.341738, states[40]= 0.004468
Saving checkpoint... 
Iteration: 1350130757, states[0] = -55.469764, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1370127166, states[0] = -51.474928, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1388614978, states[0] = -38.610101, states[40]= 0.000151
Saving checkpoint... 
Iteration: 1406418984, states[0] = -95.013311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426803570, states[0] = -94.964811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448128972, states[0] = -53.471345, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1468067133, states[0] = 2.629102, states[40]= 0.004599
Saving checkpoint... 
Iteration: 1488793548, states[0] = -94.957451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509083586, states[0] = -20.804152, states[40]= 0.000960
Saving checkpoint... 
Iteration: 1527406512, states[0] = -48.259215, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1546388041, states[0] = -95.139096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567317727, states[0] = -64.144561, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1587971061, states[0] = -9.543993, states[40]= 0.002770
Saving checkpoint... 
Iteration: 1609024620, states[0] = -75.713928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630337888, states[0] = -94.097551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650652569, states[0] = 4.743463, states[40]= 0.005418
Saving checkpoint... 
Iteration: 1670491580, states[0] = -32.748298, states[40]= 0.000328
Saving checkpoint... 
Iteration: 1691280470, states[0] = -95.138580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1710567953, states[0] = -95.259963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1732020473, states[0] = -68.923174, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1753806366, states[0] = 27.084371, states[40]= 0.109854
Saving checkpoint... 
Iteration: 1775556985, states[0] = -95.080986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797446534, states[0] = -95.007347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1819182547, states[0] = -94.835094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1840925886, states[0] = -95.033008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862038378, states[0] = 14.777599, states[40]= 0.005449
Saving checkpoint... 
Iteration: 1881378216, states[0] = -95.007045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890156305, states[0] = -92.244730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1898207826, states[0] = -94.856142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1906469510, states[0] = -95.025078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1913627242, states[0] = -51.744319, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1919594357, states[0] = -18.372502, states[40]= 0.001096
Saving checkpoint... 
Iteration: 1925740152, states[0] = -94.904359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933007099, states[0] = 24.884935, states[40]= 0.104052
Saving checkpoint... 
Iteration: 1940383796, states[0] = -95.004230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1948446294, states[0] = -95.019354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1955434143, states[0] = -95.016869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963359521, states[0] = -94.994928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971057737, states[0] = 7.079666, states[40]= 0.004892
Saving checkpoint... 
Iteration: 1978642636, states[0] = -70.405680, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1986486473, states[0] = -95.024896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993403454, states[0] = -95.009213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2000984794, states[0] = -95.024585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008157113, states[0] = -92.557426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015685122, states[0] = -94.807989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022176720, states[0] = -94.787163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029280743, states[0] = -94.946653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2037312962, states[0] = -94.970674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044969258, states[0] = -95.022309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052615884, states[0] = -39.531150, states[40]= 0.000132
Saving checkpoint... 
Iteration: 2059225785, states[0] = -94.882337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066751922, states[0] = -94.917356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2075175824, states[0] = -94.783993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2082721930, states[0] = -94.876323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2091243315, states[0] = -94.906799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098207342, states[0] = -94.851599, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.902039
 - CaMKt in component CaMK (millimolar): 0.006845
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.691406
 - nass in component intracellular_ions (millimolar): 6.691466
 - ki in component intracellular_ions (millimolar): 145.286851
 - kss in component intracellular_ions (millimolar): 145.286832
 - cansr in component intracellular_ions (millimolar): 1.309730
 - cajsr in component intracellular_ions (millimolar): 1.272444
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003618
 - hf in component INa (dimensionless): 0.880004
 - hs in component INa (dimensionless): 0.880000
 - j in component INa (dimensionless): 0.879972
 - hsp in component INa (dimensionless): 0.725838
 - jp in component INa (dimensionless): 0.879954
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.711352
 - hLp in component INaL (dimensionless): 0.456409
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.627205
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.703435
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.939680
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999899
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001595
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.326700
 - xs1 in component IKs (dimensionless): 0.231564
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997337
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:49:11 (21400): called boinc_finish(0)

</stderr_txt>
]]>


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