𝕏

Task 55283122

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_959_0
Workunit 26250697
Created 29 Jun 2024, 9:19:43 UTC
Sent 29 Jun 2024, 13:43:49 UTC
Report deadline 2 Jul 2024, 23:19:49 UTC
Received 2 Jul 2024, 17:56:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239729
Run time 2 hours 56 min 6 sec
CPU time 2 hours 55 min 51 sec
Validate state Valid
Credit 60.86
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.34 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.16.6</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_959.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_959_0_r2137656955_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_959_0_r2137656955_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 107.482244
     * GNaL_b in INaL: 0.004460
     * Gto_b in Ito: 0.080129
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030205
     * GKs_b in IKs: 0.001774
     * GK1_b in IK1: 0.163227
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 66.006675
     * GKb_b in IKb: 0.003711
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.052266
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12022202, states[0] = 19.842008, states[40]= 0.008693
Saving checkpoint... 
Iteration: 24296753, states[0] = -94.885250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36248020, states[0] = -94.826491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48235611, states[0] = -94.802249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60644665, states[0] = -68.858097, states[40]= 0.000001
Saving checkpoint... 
Iteration: 72911528, states[0] = -94.905829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84842131, states[0] = -94.879566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96793692, states[0] = -94.848618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108944696, states[0] = -94.907103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121349380, states[0] = -94.878831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133658980, states[0] = -89.516780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145610847, states[0] = -32.418532, states[40]= 0.000347
Saving checkpoint... 
Iteration: 157563275, states[0] = 4.960472, states[40]= 0.004774
Saving checkpoint... 
Iteration: 169643882, states[0] = -66.689490, states[40]= 0.000001
Saving checkpoint... 
Iteration: 181615280, states[0] = -36.620763, states[40]= 0.000201
Saving checkpoint... 
Iteration: 193591824, states[0] = -14.292425, states[40]= 0.001579
Saving checkpoint... 
Iteration: 205538804, states[0] = 15.051796, states[40]= 0.005471
Saving checkpoint... 
Iteration: 217478780, states[0] = -94.909253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229424285, states[0] = -94.900085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241364514, states[0] = -94.882829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253318070, states[0] = -94.860614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265276094, states[0] = -94.829490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277561669, states[0] = 5.714406, states[40]= 0.004820
Saving checkpoint... 
Iteration: 289860110, states[0] = -94.881047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302280898, states[0] = -94.833713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314598121, states[0] = -20.244463, states[40]= 0.000950
Saving checkpoint... 
Iteration: 326565236, states[0] = 4.053346, states[40]= 0.004709
Saving checkpoint... 
Iteration: 338696564, states[0] = -94.719123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351086281, states[0] = -9.295339, states[40]= 0.002501
Saving checkpoint... 
Iteration: 363454461, states[0] = -94.905534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375830849, states[0] = -94.867635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387900559, states[0] = -94.894196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399843404, states[0] = -94.873814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411815373, states[0] = -94.858843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423761209, states[0] = -94.814705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435895787, states[0] = -94.892858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448172281, states[0] = -94.559622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460120952, states[0] = -42.125273, states[40]= 0.000090
Saving checkpoint... 
Iteration: 472107726, states[0] = -29.376696, states[40]= 0.000484
Saving checkpoint... 
Iteration: 484038907, states[0] = 15.016201, states[40]= 0.005465
Saving checkpoint... 
Iteration: 496008023, states[0] = 24.520929, states[40]= 0.083226
Saving checkpoint... 
Iteration: 507958822, states[0] = -94.906133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519912455, states[0] = -94.897132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531854478, states[0] = -94.878602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543803476, states[0] = -94.851038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555767567, states[0] = -94.821161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567714056, states[0] = -94.750522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579719511, states[0] = -94.759498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591745751, states[0] = -94.796808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603995416, states[0] = -94.910845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616272124, states[0] = -94.825552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628672962, states[0] = -94.582235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641085508, states[0] = -8.642623, states[40]= 0.002640
Saving checkpoint... 
Iteration: 653423135, states[0] = -94.899485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665386245, states[0] = -94.889919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677562537, states[0] = 5.318948, states[40]= 0.004796
Saving checkpoint... 
Iteration: 689817850, states[0] = -94.860171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701758057, states[0] = -94.811135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713705650, states[0] = -94.735776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725942054, states[0] = -94.903194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738312659, states[0] = -94.856964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750710776, states[0] = -94.744807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763112236, states[0] = -33.675946, states[40]= 0.000298
Saving checkpoint... 
Iteration: 775073426, states[0] = -0.218544, states[40]= 0.004260
Saving checkpoint... 
Iteration: 787140163, states[0] = -62.219875, states[40]= 0.000003
Saving checkpoint... 
Iteration: 799286254, states[0] = -94.837921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811666397, states[0] = -93.974534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823779153, states[0] = -94.831861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835832714, states[0] = -94.868327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847781580, states[0] = -94.833963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859764120, states[0] = -94.817488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872144232, states[0] = -67.074308, states[40]= 0.000001
Saving checkpoint... 
Iteration: 884539245, states[0] = 14.889745, states[40]= 0.005445
Saving checkpoint... 
Iteration: 896947483, states[0] = -94.904051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909363805, states[0] = -94.882089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921762965, states[0] = -94.816253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934190280, states[0] = -94.706317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946598520, states[0] = -20.623501, states[40]= 0.000925
Saving checkpoint... 
Iteration: 958772243, states[0] = -94.825459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971020738, states[0] = 20.787603, states[40]= 0.009535
Saving checkpoint... 
Iteration: 983295940, states[0] = -94.845379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995509668, states[0] = 23.552635, states[40]= 0.057293
Saving checkpoint... 
Iteration: 1007455012, states[0] = -94.905235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019631481, states[0] = -52.844287, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1032018551, states[0] = 21.300408, states[40]= 0.011692
Saving checkpoint... 
Iteration: 1044405169, states[0] = -94.895011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056814108, states[0] = -94.857677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069220310, states[0] = -94.760482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081477342, states[0] = -94.908413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093768072, states[0] = -94.821339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105970673, states[0] = -94.907507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118377573, states[0] = -94.886872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130789537, states[0] = -94.840372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143206181, states[0] = -94.736471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155613389, states[0] = -34.778946, states[40]= 0.000258
Saving checkpoint... 
Iteration: 1168002193, states[0] = 43.750129, states[40]= 0.094424
Saving checkpoint... 
Iteration: 1180390239, states[0] = -94.890814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192693017, states[0] = -94.711696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204845503, states[0] = -94.874295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217006666, states[0] = 25.899247, states[40]= 0.110653
Saving checkpoint... 
Iteration: 1229405739, states[0] = -94.895046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241797604, states[0] = -94.846451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253931143, states[0] = -94.900797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266034076, states[0] = 16.768192, states[40]= 0.005832
Saving checkpoint... 
Iteration: 1278008334, states[0] = 24.293942, states[40]= 0.077642
Saving checkpoint... 
Iteration: 1290054486, states[0] = 8.838820, states[40]= 0.004975
Saving checkpoint... 
Iteration: 1301996261, states[0] = -94.910519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313935207, states[0] = -94.901561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325876210, states[0] = -94.886290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338048475, states[0] = 11.300557, states[40]= 0.005098
Saving checkpoint... 
Iteration: 1350247221, states[0] = -94.798168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362199463, states[0] = -94.724003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374170205, states[0] = -94.453561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386338050, states[0] = -94.870674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398280464, states[0] = -94.832666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410490718, states[0] = -94.909841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422896900, states[0] = -94.892577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435298022, states[0] = -94.846640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447685512, states[0] = -94.695288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460077644, states[0] = -2.797694, states[40]= 0.003849
Saving checkpoint... 
Iteration: 1472206840, states[0] = -94.737451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484138581, states[0] = -60.440875, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1496075135, states[0] = -1.224143, states[40]= 0.004113
Saving checkpoint... 
Iteration: 1507978724, states[0] = -94.999861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1519852880, states[0] = 5.837776, states[40]= 0.005458
Saving checkpoint... 
Iteration: 1531985299, states[0] = -95.032021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543937396, states[0] = -89.296271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555973515, states[0] = -95.019700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567889022, states[0] = -27.359953, states[40]= 0.000577
Saving checkpoint... 
Iteration: 1579806996, states[0] = 26.687113, states[40]= 0.096317
Saving checkpoint... 
Iteration: 1591728278, states[0] = -95.123551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1603626773, states[0] = -72.930056, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1615527201, states[0] = 17.979553, states[40]= 0.007898
Saving checkpoint... 
Iteration: 1627420663, states[0] = -95.116078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1639332418, states[0] = -82.970166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651235929, states[0] = 14.050406, states[40]= 0.006529
Saving checkpoint... 
Iteration: 1663493582, states[0] = -95.186419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675743835, states[0] = -95.145418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1688113036, states[0] = 22.996509, states[40]= 0.029053
Saving checkpoint... 
Iteration: 1700081510, states[0] = -95.178627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711997788, states[0] = -95.081060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723916774, states[0] = -59.423638, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1735832583, states[0] = 15.610645, states[40]= 0.006913
Saving checkpoint... 
Iteration: 1747833345, states[0] = 15.260091, states[40]= 0.006815
Saving checkpoint... 
Iteration: 1760176516, states[0] = -14.057460, states[40]= 0.001817
Saving checkpoint... 
Iteration: 1772540724, states[0] = -93.263251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1784498001, states[0] = -37.668222, states[40]= 0.000176
Saving checkpoint... 
Iteration: 1796704640, states[0] = 31.459781, states[40]= 0.124896
Saving checkpoint... 
Iteration: 1809038955, states[0] = 14.315185, states[40]= 0.005446
Saving checkpoint... 
Iteration: 1821161053, states[0] = -93.230516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833181226, states[0] = -94.709203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845212937, states[0] = -94.765948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857423964, states[0] = -94.911338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869453425, states[0] = -94.913209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1881351584, states[0] = -94.882792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1893251258, states[0] = -94.807182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905283317, states[0] = -94.837948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1917211490, states[0] = -94.747591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1929394039, states[0] = -94.892999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941739763, states[0] = -94.789398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954065438, states[0] = 3.938073, states[40]= 0.004701
Saving checkpoint... 
Iteration: 1966387903, states[0] = -94.890145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1978684513, states[0] = -94.692707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991025100, states[0] = 19.633266, states[40]= 0.007396
Saving checkpoint... 
Iteration: 2003337322, states[0] = -94.870089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015664335, states[0] = -93.392230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027981416, states[0] = -94.908409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2040314124, states[0] = -94.857114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052638935, states[0] = -60.838085, states[40]= 0.000004
Saving checkpoint... 
Iteration: 2064918181, states[0] = -94.897525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2077249899, states[0] = -94.800944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2089364756, states[0] = -94.881710, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.786276
 - CaMKt in component CaMK (millimolar): 0.006809
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.711180
 - nass in component intracellular_ions (millimolar): 6.711237
 - ki in component intracellular_ions (millimolar): 145.268449
 - kss in component intracellular_ions (millimolar): 145.268431
 - cansr in component intracellular_ions (millimolar): 1.304511
 - cajsr in component intracellular_ions (millimolar): 1.267094
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003661
 - hf in component INa (dimensionless): 0.877981
 - hs in component INa (dimensionless): 0.877977
 - j in component INa (dimensionless): 0.877950
 - hsp in component INa (dimensionless): 0.722038
 - jp in component INa (dimensionless): 0.877932
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.707324
 - hLp in component INaL (dimensionless): 0.449889
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.622917
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.698103
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938021
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999893
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001578
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332066
 - xs1 in component IKs (dimensionless): 0.235078
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997367
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:56:22 (218416): called boinc_finish(0)

</stderr_txt>
]]>


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