𝕏

Task 55277429

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-Coppini_2000-conf_735_1
Workunit 26247852
Created 29 Jun 2024, 9:16:29 UTC
Sent 29 Jun 2024, 13:00:33 UTC
Report deadline 2 Jul 2024, 13:00:33 UTC
Received 29 Jun 2024, 21:49:05 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 52 min 52 sec
CPU time 1 hours 45 min 3 sec
Validate state Valid
Credit 44.76
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.07 MB
Peak swap size 4.13 GB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Coppini_2000-conf_735.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Coppini_2000-conf_735_1_r1481085679_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Coppini_2000-conf_735_1_r1481085679_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.525595
     * GNaL_b in INaL: 0.006905
     * Gto_b in Ito: 0.083573
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030588
     * GKs_b in IKs: 0.001752
     * GK1_b in IK1: 0.167805
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 69.675216
     * GKb_b in IKb: 0.003727
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020724
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11507372, states[0] = -94.790011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23394785, states[0] = -94.683566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35796921, states[0] = -94.730204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47722395, states[0] = -94.716206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58777020, states[0] = -94.709125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70618703, states[0] = -94.698181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82172228, states[0] = -59.013872, states[40]= 0.000025
Saving checkpoint... 
Iteration: 93599347, states[0] = -94.690130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104824188, states[0] = -94.695497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116547494, states[0] = -94.679482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127191647, states[0] = -82.707706, states[40]= 0.000001
Saving checkpoint... 
Iteration: 138006918, states[0] = 27.636177, states[40]= 0.133574
Saving checkpoint... 
Iteration: 149394574, states[0] = -94.615039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159988825, states[0] = -94.688174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171964792, states[0] = -94.688427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182698766, states[0] = -94.690055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193554624, states[0] = -94.677340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204654641, states[0] = -94.687836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215143622, states[0] = -33.103952, states[40]= 0.001041
Saving checkpoint... 
Iteration: 225645100, states[0] = -94.687062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235868442, states[0] = -94.689656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245173761, states[0] = -59.687456, states[40]= 0.000022
Saving checkpoint... 
Iteration: 256279606, states[0] = -94.451870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266348059, states[0] = -94.568688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276639960, states[0] = -94.686472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287576901, states[0] = -94.680137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298740426, states[0] = -94.690073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309950265, states[0] = -94.687681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321167314, states[0] = -53.519906, states[40]= 0.000062
Saving checkpoint... 
Iteration: 332912497, states[0] = -94.688483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344840708, states[0] = -94.689728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356636673, states[0] = -94.686050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368088552, states[0] = 6.029245, states[40]= 0.004642
Saving checkpoint... 
Iteration: 379916122, states[0] = -94.688312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392103781, states[0] = -2.336700, states[40]= 0.004141
Saving checkpoint... 
Iteration: 404106645, states[0] = -4.224225, states[40]= 0.003806
Saving checkpoint... 
Iteration: 415621659, states[0] = -94.684765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427710345, states[0] = -94.689276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439727823, states[0] = -94.689612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451352400, states[0] = -94.573346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462167847, states[0] = -54.015761, states[40]= 0.000057
Saving checkpoint... 
Iteration: 473487247, states[0] = -94.660215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484461872, states[0] = -94.650964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496085947, states[0] = 7.261711, states[40]= 0.004596
Saving checkpoint... 
Iteration: 507427850, states[0] = -94.634615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519550367, states[0] = -94.675523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530638029, states[0] = -94.685827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542913701, states[0] = -94.688069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554538613, states[0] = -94.673244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565891089, states[0] = -94.688490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577528451, states[0] = -94.671076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589497674, states[0] = -94.663215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600467830, states[0] = -94.653121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611265904, states[0] = -94.416499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621808957, states[0] = -94.689553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632751444, states[0] = -94.689553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643210195, states[0] = -94.128310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652926993, states[0] = -94.687580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664016638, states[0] = 27.477516, states[40]= 0.006306
Saving checkpoint... 
Iteration: 674707947, states[0] = -94.688773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684255074, states[0] = -94.385592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695068702, states[0] = 14.445706, states[40]= 0.003856
Saving checkpoint... 
Iteration: 705956279, states[0] = -94.686804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716606126, states[0] = -94.682782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727737074, states[0] = -94.689232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738706752, states[0] = -94.688628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749968188, states[0] = -94.686436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761693716, states[0] = -94.688205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771988456, states[0] = -94.685891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782057816, states[0] = 18.247868, states[40]= 0.003159
Saving checkpoint... 
Iteration: 793197967, states[0] = -90.667700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804195942, states[0] = -88.547598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814952924, states[0] = -94.686689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825305084, states[0] = -94.503805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835971375, states[0] = -94.686203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846453906, states[0] = -94.646942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857345444, states[0] = -94.564395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868684371, states[0] = -94.687684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879353047, states[0] = -94.573311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890171556, states[0] = -57.527840, states[40]= 0.000032
Saving checkpoint... 
Iteration: 900994993, states[0] = -94.685493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912107665, states[0] = -4.926270, states[40]= 0.003665
Saving checkpoint... 
Iteration: 923135161, states[0] = -26.456333, states[40]= 0.001604
Saving checkpoint... 
Iteration: 934505677, states[0] = -94.664857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945468278, states[0] = -94.652675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956154073, states[0] = -41.656549, states[40]= 0.000367
Saving checkpoint... 
Iteration: 966526019, states[0] = -94.669838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977298696, states[0] = -94.491478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988317300, states[0] = -94.524507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998145176, states[0] = -34.325243, states[40]= 0.000917
Saving checkpoint... 
Iteration: 1009620303, states[0] = -94.683583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019221456, states[0] = -94.268181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029142726, states[0] = -32.374053, states[40]= 0.001118
Saving checkpoint... 
Iteration: 1038963620, states[0] = -94.686030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049788573, states[0] = -94.688891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060337368, states[0] = -94.553757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071417621, states[0] = -94.627607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081530798, states[0] = -94.670682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092238486, states[0] = -94.331771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103900883, states[0] = -94.687331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114925285, states[0] = -94.686790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126887684, states[0] = -94.687550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137221528, states[0] = -94.268300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148398744, states[0] = -94.614784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158882688, states[0] = -94.687587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170409898, states[0] = -94.622509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182531075, states[0] = -94.670560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194546214, states[0] = -94.673559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205724182, states[0] = -94.688175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216880189, states[0] = -94.687529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227355380, states[0] = -94.575301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238417327, states[0] = -94.627126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248503962, states[0] = -94.663823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259610829, states[0] = -94.682272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270864424, states[0] = -94.687707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281866045, states[0] = -94.687661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292981207, states[0] = -94.685139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304122746, states[0] = -16.678471, states[40]= 0.001571
Saving checkpoint... 
Iteration: 1315048557, states[0] = 21.129067, states[40]= 0.002558
Saving checkpoint... 
Iteration: 1325765080, states[0] = -94.688389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336895097, states[0] = -94.687030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347842787, states[0] = -94.687894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358226819, states[0] = -94.289680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369133199, states[0] = -24.935875, states[40]= 0.001628
Saving checkpoint... 
Iteration: 1380109605, states[0] = -6.306544, states[40]= 0.003370
Saving checkpoint... 
Iteration: 1390735948, states[0] = -94.688030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401732087, states[0] = -94.687955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413249087, states[0] = -94.365922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425021966, states[0] = 27.184884, states[40]= 0.002293
Saving checkpoint... 
Iteration: 1436018645, states[0] = 27.431493, states[40]= 0.003909
Saving checkpoint... 
Iteration: 1447064087, states[0] = 16.120225, states[40]= 0.003572
Saving checkpoint... 
Iteration: 1457334063, states[0] = -94.548596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468437798, states[0] = -94.638199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479506857, states[0] = -94.664199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490421824, states[0] = -94.629387, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.560230
 - CaMKt in component CaMK (millimolar): 0.004235
 - cass in component intracellular_ions (millimolar): 0.000084
 - nai in component intracellular_ions (millimolar): 6.502657
 - nass in component intracellular_ions (millimolar): 6.502743
 - ki in component intracellular_ions (millimolar): 145.410900
 - kss in component intracellular_ions (millimolar): 145.410885
 - cansr in component intracellular_ions (millimolar): 1.585420
 - cajsr in component intracellular_ions (millimolar): 1.584730
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.003745
 - hf in component INa (dimensionless): 0.873945
 - hs in component INa (dimensionless): 0.873946
 - j in component INa (dimensionless): 0.873951
 - hsp in component INa (dimensionless): 0.714551
 - jp in component INa (dimensionless): 0.873954
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.719897
 - hLp in component INaL (dimensionless): 0.510921
 - a in component Ito (dimensionless): 0.000638
 - iF in component Ito (dimensionless): 0.999862
 - iS in component Ito (dimensionless): 0.889495
 - ap in component Ito (dimensionless): 0.000325
 - iFp in component Ito (dimensionless): 0.999862
 - iSp in component Ito (dimensionless): 0.929603
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.973746
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002669
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.100815
 - xs1 in component IKs (dimensionless): 0.131121
 - xs2 in component IKs (dimensionless): 0.000091
 - xk1 in component IK1 (dimensionless): 0.997425
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:19:01 (88121): called boinc_finish(0)

</stderr_txt>
]]>


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