𝕏

Task 55277427

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-Coppini_2000-conf_635_1
Workunit 26247851
Created 29 Jun 2024, 9:16:29 UTC
Sent 29 Jun 2024, 13:00:33 UTC
Report deadline 2 Jul 2024, 13:00:33 UTC
Received 29 Jun 2024, 21:49:05 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 51 min 55 sec
CPU time 1 hours 46 min 16 sec
Validate state Valid
Credit 43.53
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.10 MB
Peak swap size 4.13 GB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Coppini_2000-conf_635.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Coppini_2000-conf_635_1_r525947231_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Coppini_2000-conf_635_1_r525947231_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 113.984616
     * GNaL_b in INaL: 0.005356
     * Gto_b in Ito: 0.076052
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033111
     * GKs_b in IKs: 0.002135
     * GK1_b in IK1: 0.175301
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.571591
     * GKb_b in IKb: 0.003883
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025859
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11758565, states[0] = -94.901607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22869914, states[0] = -94.850056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34664251, states[0] = -94.822067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43903814, states[0] = -94.811003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54748930, states[0] = -94.803722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66481897, states[0] = -94.770041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78025069, states[0] = 26.081990, states[40]= 0.002208
Saving checkpoint... 
Iteration: 88823055, states[0] = -94.790670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99782534, states[0] = -94.788939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110608942, states[0] = -94.781996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121296316, states[0] = -94.608009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131212903, states[0] = -94.379358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141771558, states[0] = -94.785004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151278693, states[0] = -94.572234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161578850, states[0] = -94.775675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171723105, states[0] = -94.783589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180706378, states[0] = -94.783088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191704199, states[0] = -94.782852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202792949, states[0] = -94.783338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213868478, states[0] = -94.782349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224819123, states[0] = -94.782935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235716919, states[0] = -94.782688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247382330, states[0] = -94.706333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259071612, states[0] = 10.533115, states[40]= 0.004555
Saving checkpoint... 
Iteration: 270379489, states[0] = -94.704062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282025891, states[0] = 26.023710, states[40]= 0.002212
Saving checkpoint... 
Iteration: 293449867, states[0] = -94.744086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305036650, states[0] = 23.280696, states[40]= 0.002433
Saving checkpoint... 
Iteration: 316541789, states[0] = -94.769017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328740840, states[0] = -94.782697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339738923, states[0] = -94.782658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351009241, states[0] = 27.749205, states[40]= 0.062518
Saving checkpoint... 
Iteration: 361210710, states[0] = -94.367991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372750692, states[0] = -94.782685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383873998, states[0] = -94.781693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395115215, states[0] = -20.024609, states[40]= 0.001324
Saving checkpoint... 
Iteration: 406604099, states[0] = -94.776779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418753872, states[0] = -94.782621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430367032, states[0] = -94.693447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441358207, states[0] = -94.685365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453299357, states[0] = -94.609460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464807169, states[0] = -94.782431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476915060, states[0] = -94.780745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487745701, states[0] = -94.782456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498276750, states[0] = -94.566042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509090864, states[0] = 0.338835, states[40]= 0.004621
Saving checkpoint... 
Iteration: 519542970, states[0] = -94.768858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529621133, states[0] = -94.777975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540763003, states[0] = -94.782446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551618266, states[0] = -94.777720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561458674, states[0] = -94.747018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572419615, states[0] = -94.729487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583145896, states[0] = -48.465390, states[40]= 0.000115
Saving checkpoint... 
Iteration: 592949858, states[0] = -94.779790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603581431, states[0] = -94.774125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614387283, states[0] = -94.709263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625437141, states[0] = -94.738039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636514181, states[0] = -94.763059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647032202, states[0] = 24.522890, states[40]= 0.002250
Saving checkpoint... 
Iteration: 657851960, states[0] = -94.781585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668828984, states[0] = -94.781873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679776024, states[0] = -94.782217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690325950, states[0] = -94.648837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701539823, states[0] = -94.768012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711408494, states[0] = -94.722996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721985262, states[0] = -94.778743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732822750, states[0] = -94.781835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743235815, states[0] = -94.456864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754380627, states[0] = -94.704064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764935674, states[0] = -94.779818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775328500, states[0] = -94.651982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786949827, states[0] = -94.779464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797599645, states[0] = -94.775707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807997272, states[0] = -94.778308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819142616, states[0] = -45.244114, states[40]= 0.000184
Saving checkpoint... 
Iteration: 829475060, states[0] = -94.752231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840661022, states[0] = -94.779819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851319769, states[0] = -94.640240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862433419, states[0] = -94.735921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872981194, states[0] = -94.778587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884311768, states[0] = -94.628618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894750847, states[0] = -94.781804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905466199, states[0] = -94.749146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915570096, states[0] = -94.772217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925518743, states[0] = -94.763566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934666298, states[0] = -94.779892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945514097, states[0] = -94.762521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955593657, states[0] = -94.774854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966757773, states[0] = -94.781715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978001613, states[0] = 48.680016, states[40]= 0.317676
Saving checkpoint... 
Iteration: 988859011, states[0] = -94.780921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999302103, states[0] = -94.613153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010702099, states[0] = -94.780927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021035872, states[0] = 23.507103, states[40]= 0.002397
Saving checkpoint... 
Iteration: 1031957199, states[0] = -94.778884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042599619, states[0] = -94.775293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053715096, states[0] = -94.781125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064135399, states[0] = -38.380812, states[40]= 0.000463
Saving checkpoint... 
Iteration: 1075023615, states[0] = 26.465581, states[40]= 0.002396
Saving checkpoint... 
Iteration: 1086371195, states[0] = -94.695913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098124969, states[0] = -28.858901, states[40]= 0.001137
Saving checkpoint... 
Iteration: 1109084989, states[0] = 3.843589, states[40]= 0.004826
Saving checkpoint... 
Iteration: 1120099939, states[0] = -6.214710, states[40]= 0.003493
Saving checkpoint... 
Iteration: 1131109991, states[0] = -15.171775, states[40]= 0.001692
Saving checkpoint... 
Iteration: 1141495589, states[0] = -94.757692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151978042, states[0] = -94.778193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163184017, states[0] = -93.288477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173936695, states[0] = -94.779109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185127081, states[0] = -30.766677, states[40]= 0.001010
Saving checkpoint... 
Iteration: 1195905116, states[0] = -94.779740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206875472, states[0] = -94.780281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217723380, states[0] = -94.780986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228611002, states[0] = -94.775998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239330024, states[0] = -94.653124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250657392, states[0] = -94.778961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260987260, states[0] = -94.777789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271915403, states[0] = -94.779402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283591975, states[0] = -94.774131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294103127, states[0] = -8.910842, states[40]= 0.002870
Saving checkpoint... 
Iteration: 1304914266, states[0] = -94.779370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316315135, states[0] = -94.632867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327521641, states[0] = -94.763500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338267304, states[0] = -94.543322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349434406, states[0] = -94.735563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359592212, states[0] = -94.774028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370622568, states[0] = -94.776668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382116906, states[0] = -21.572408, states[40]= 0.001297
Saving checkpoint... 
Iteration: 1393612425, states[0] = -94.775839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403910641, states[0] = -94.779278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413804259, states[0] = -94.780859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425940955, states[0] = -94.778591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440009848, states[0] = 27.666816, states[40]= 0.051271
Saving checkpoint... 
Iteration: 1454616040, states[0] = -94.776029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467970815, states[0] = -94.777833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478816539, states[0] = -94.780645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489666866, states[0] = -94.778983, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.653017
 - CaMKt in component CaMK (millimolar): 0.004162
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.471870
 - nass in component intracellular_ions (millimolar): 6.471957
 - ki in component intracellular_ions (millimolar): 145.440750
 - kss in component intracellular_ions (millimolar): 145.440735
 - cansr in component intracellular_ions (millimolar): 1.593764
 - cajsr in component intracellular_ions (millimolar): 1.592983
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.003711
 - hf in component INa (dimensionless): 0.875615
 - hs in component INa (dimensionless): 0.875616
 - j in component INa (dimensionless): 0.875621
 - hsp in component INa (dimensionless): 0.717650
 - jp in component INa (dimensionless): 0.875624
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.722425
 - hLp in component INaL (dimensionless): 0.516105
 - a in component Ito (dimensionless): 0.000634
 - iF in component Ito (dimensionless): 0.999864
 - iS in component Ito (dimensionless): 0.894611
 - ap in component Ito (dimensionless): 0.000323
 - iFp in component Ito (dimensionless): 0.999864
 - iSp in component Ito (dimensionless): 0.934172
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.976680
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002754
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.095619
 - xs1 in component IKs (dimensionless): 0.120313
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997402
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:28:41 (88182): called boinc_finish(0)

</stderr_txt>
]]>


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