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Task 55274589

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_630_0
Workunit 26246433
Created 29 Jun 2024, 9:14:59 UTC
Sent 29 Jun 2024, 12:36:16 UTC
Report deadline 2 Jul 2024, 22:12:16 UTC
Received 29 Jun 2024, 14:48:01 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234818
Run time 46 min 50 sec
CPU time 39 min 46 sec
Validate state Valid
Credit 58.24
Device peak FLOPS 5.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.45 MB
Peak swap size 391.85 GB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>7.24.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_630.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_630_0_r1666627331_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_630_0_r1666627331_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 96.965687
     * GNaL_b in INaL: 0.005937
     * Gto_b in Ito: 0.077264
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030604
     * GKs_b in IKs: 0.001808
     * GK1_b in IK1: 0.161067
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 73.474658
     * GKb_b in IKb: 0.003919
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.053585
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 32193749, states[0] = -94.774448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58262434, states[0] = -94.845987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86011022, states[0] = 23.588903, states[40]= 0.041100
Saving checkpoint... 
Iteration: 114527063, states[0] = 19.898452, states[40]= 0.006867
Saving checkpoint... 
Iteration: 144783939, states[0] = -94.844538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171524959, states[0] = 20.526165, states[40]= 0.007451
Saving checkpoint... 
Iteration: 200888767, states[0] = -94.898538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231089891, states[0] = -8.980845, states[40]= 0.002507
Saving checkpoint... 
Iteration: 259415265, states[0] = -94.905348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291458976, states[0] = -94.913733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320855464, states[0] = -94.886256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349296043, states[0] = -94.852435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377887631, states[0] = -94.897777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405076353, states[0] = 0.163228, states[40]= 0.004225
Saving checkpoint... 
Iteration: 431865241, states[0] = -94.890086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459792110, states[0] = -94.849340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489583417, states[0] = -4.132178, states[40]= 0.003518
Saving checkpoint... 
Iteration: 520175218, states[0] = -94.471516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550231314, states[0] = -94.783020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580465662, states[0] = -94.914562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607631815, states[0] = -47.994450, states[40]= 0.000036
Saving checkpoint... 
Iteration: 633645602, states[0] = -62.869481, states[40]= 0.000003
Saving checkpoint... 
Iteration: 662174641, states[0] = -94.429085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692344506, states[0] = -94.881207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721852722, states[0] = -94.884864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753538931, states[0] = 16.022596, states[40]= 0.005420
Saving checkpoint... 
Iteration: 781229246, states[0] = -94.779857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812511793, states[0] = 23.450530, states[40]= 0.034872
Saving checkpoint... 
Iteration: 841724086, states[0] = -94.771994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870541647, states[0] = 15.029008, states[40]= 0.005277
Saving checkpoint... 
Iteration: 898284277, states[0] = -94.842687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926142364, states[0] = -59.201798, states[40]= 0.000005
Saving checkpoint... 
Iteration: 954165626, states[0] = -91.201702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984386466, states[0] = -94.897083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014716201, states[0] = -94.759244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044307256, states[0] = -94.860052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072084385, states[0] = -4.796617, states[40]= 0.003387
Saving checkpoint... 
Iteration: 1101319036, states[0] = -94.867508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131089270, states[0] = -8.470388, states[40]= 0.002614
Saving checkpoint... 
Iteration: 1158647389, states[0] = -64.987419, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1188155642, states[0] = -76.378657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213591983, states[0] = -10.727086, states[40]= 0.002154
Saving checkpoint... 
Iteration: 1242268091, states[0] = -94.827497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271747665, states[0] = -94.804619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301712499, states[0] = -94.752866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332646489, states[0] = -63.910044, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1360879473, states[0] = -94.894633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390401333, states[0] = -94.901159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422257469, states[0] = -94.816105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453947498, states[0] = -94.911185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484753436, states[0] = -94.811450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1514897533, states[0] = -95.050494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1547279579, states[0] = -95.040208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1575825386, states[0] = -95.129292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605676479, states[0] = -10.886227, states[40]= 0.002408
Saving checkpoint... 
Iteration: 1637461566, states[0] = 1.158254, states[40]= 0.004914
Saving checkpoint... 
Iteration: 1669582542, states[0] = -17.278723, states[40]= 0.001313
Saving checkpoint... 
Iteration: 1695613651, states[0] = 23.309989, states[40]= 0.025599
Saving checkpoint... 
Iteration: 1723579471, states[0] = -14.048642, states[40]= 0.001787
Saving checkpoint... 
Iteration: 1753280165, states[0] = -14.776955, states[40]= 0.001666
Saving checkpoint... 
Iteration: 1783193207, states[0] = -95.199415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1814286864, states[0] = -94.886460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845205112, states[0] = -94.757506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1875702489, states[0] = -94.742029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904061161, states[0] = 7.304528, states[40]= 0.004826
Saving checkpoint... 
Iteration: 1930899315, states[0] = -94.901608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1959911272, states[0] = -94.903914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1985334913, states[0] = -94.876031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013609037, states[0] = -26.234515, states[40]= 0.000642
Saving checkpoint... 
Iteration: 2040145655, states[0] = -62.934029, states[40]= 0.000003
Saving checkpoint... 
Iteration: 2071592041, states[0] = -10.777292, states[40]= 0.002144
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.793830
 - CaMKt in component CaMK (millimolar): 0.006646
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.511942
 - nass in component intracellular_ions (millimolar): 6.511998
 - ki in component intracellular_ions (millimolar): 145.472219
 - kss in component intracellular_ions (millimolar): 145.472201
 - cansr in component intracellular_ions (millimolar): 1.285753
 - cajsr in component intracellular_ions (millimolar): 1.247964
 - cai in component intracellular_ions (millimolar): 0.000073
 - m in component INa (dimensionless): 0.003658
 - hf in component INa (dimensionless): 0.878114
 - hs in component INa (dimensionless): 0.878110
 - j in component INa (dimensionless): 0.878083
 - hsp in component INa (dimensionless): 0.722287
 - jp in component INa (dimensionless): 0.878065
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.706371
 - hLp in component INaL (dimensionless): 0.446686
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.617645
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.691579
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933453
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999878
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001500
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.336837
 - xs1 in component IKs (dimensionless): 0.244880
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997365
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:42:52 (80348): called boinc_finish(0)

</stderr_txt>
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