𝕏

Task 55269865

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_3000-conf_821_0
Workunit 26244071
Created 29 Jun 2024, 9:12:26 UTC
Sent 29 Jun 2024, 12:01:17 UTC
Report deadline 2 Jul 2024, 12:01:17 UTC
Received 2 Jul 2024, 8:11:18 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 41 min 4 sec
CPU time 37 min 7 sec
Validate state Valid
Credit 42.61
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.56 MB
Peak swap size 391.88 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_3000-conf_821.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_3000-conf_821_0_r1067901176_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_3000-conf_821_0_r1067901176_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.250353
     * GNaL_b in INaL: 0.006177
     * Gto_b in Ito: 0.076906
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030905
     * GKs_b in IKs: 0.001967
     * GK1_b in IK1: 0.179128
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 67.380706
     * GKb_b in IKb: 0.003908
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037387
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10232550, states[0] = -94.456827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20003712, states[0] = -94.413442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28020682, states[0] = -94.403695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36432291, states[0] = -94.368889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45424065, states[0] = -94.363404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55420367, states[0] = -94.384104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67012340, states[0] = -94.401370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77825803, states[0] = -94.393886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89101714, states[0] = -94.418092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100178417, states[0] = -94.404454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110267666, states[0] = -94.422284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121083507, states[0] = -94.411229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129991403, states[0] = -94.415814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137592265, states[0] = -94.412405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147739413, states[0] = -94.426656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158326902, states[0] = -94.424200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170026441, states[0] = -94.419056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180066987, states[0] = 19.495401, states[40]= 0.000002
Saving checkpoint... 
Iteration: 190909318, states[0] = -94.376014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200604650, states[0] = -94.413505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208999704, states[0] = -94.413922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219344486, states[0] = -94.311279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229974236, states[0] = -94.406757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240533579, states[0] = -94.420161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249259050, states[0] = -94.100768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259864979, states[0] = -94.336670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268651218, states[0] = -48.013687, states[40]= 0.000127
Saving checkpoint... 
Iteration: 277367084, states[0] = -94.404083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288595606, states[0] = -94.425768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298421178, states[0] = -94.402281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308159551, states[0] = -94.427357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316761669, states[0] = -94.109998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325566886, states[0] = 19.513629, states[40]= 0.000002
Saving checkpoint... 
Iteration: 335703107, states[0] = -94.408345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345188854, states[0] = -93.475371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356323392, states[0] = -94.422937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365781327, states[0] = -94.405310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376158408, states[0] = -94.409279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386450716, states[0] = -94.417261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396306707, states[0] = -94.241424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405819554, states[0] = -94.422308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414091156, states[0] = 8.150330, states[40]= 0.000047
Saving checkpoint... 
Iteration: 423917692, states[0] = -94.418054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434259130, states[0] = -94.423925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445234656, states[0] = -94.405567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455588872, states[0] = -94.410610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465748597, states[0] = -94.423728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475281385, states[0] = -94.403585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483656921, states[0] = -94.424596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494035907, states[0] = -94.416682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504162614, states[0] = -61.561315, states[40]= 0.000024
Saving checkpoint... 
Iteration: 514269145, states[0] = -94.403355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524665861, states[0] = -94.406672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534272488, states[0] = -94.145342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544240430, states[0] = -94.403810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553942276, states[0] = -94.389492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562696906, states[0] = -93.733656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573099391, states[0] = 3.278359, states[40]= 0.000110
Saving checkpoint... 
Iteration: 583443309, states[0] = -94.397222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594262124, states[0] = -94.107295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604164277, states[0] = -94.405474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616301677, states[0] = -94.400727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626484134, states[0] = -94.412090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636948845, states[0] = -94.413389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645525900, states[0] = -94.412707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655017087, states[0] = -94.410290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664650647, states[0] = -47.340458, states[40]= 0.000137
Saving checkpoint... 
Iteration: 675637518, states[0] = -94.421297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684947690, states[0] = -94.412678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694431341, states[0] = -94.395781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705045632, states[0] = 25.557038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714210028, states[0] = -93.833225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724142904, states[0] = -94.404348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731555668, states[0] = -94.407541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741163558, states[0] = -62.733472, states[40]= 0.000020
Saving checkpoint... 
Iteration: 751503828, states[0] = 14.655963, states[40]= 1.080674
Saving checkpoint... 
Iteration: 763447404, states[0] = -94.394270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772757019, states[0] = -94.084356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781008463, states[0] = -94.408653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789114837, states[0] = -8.845735, states[40]= 0.000268
Saving checkpoint... 
Iteration: 798221762, states[0] = -93.906931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807024414, states[0] = 26.006921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817804983, states[0] = -94.230849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828986961, states[0] = -94.408779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839128476, states[0] = -94.418508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849243248, states[0] = -94.022388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858291995, states[0] = -94.198411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867387158, states[0] = -94.349027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875623759, states[0] = -94.402663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885534964, states[0] = -94.410370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896378693, states[0] = -94.412220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906789612, states[0] = -94.415492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916887388, states[0] = -94.348441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925529327, states[0] = 26.530284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934145669, states[0] = -94.400932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943288465, states[0] = -94.395969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952957029, states[0] = -94.389477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963666713, states[0] = -94.417074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972840250, states[0] = -94.412564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983889156, states[0] = -94.392357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993061266, states[0] = 21.530122, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1000947019, states[0] = -94.384571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009015125, states[0] = -94.404784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019628089, states[0] = -94.400227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029433119, states[0] = -94.377510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039464465, states[0] = -94.389468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049815506, states[0] = -94.393456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060073136, states[0] = -94.401670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070494874, states[0] = -94.404638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081114370, states[0] = -94.399764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091704844, states[0] = -94.396356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100542494, states[0] = -94.402236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110318968, states[0] = -94.255301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119521054, states[0] = -94.404384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129145180, states[0] = -94.397870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135985507, states[0] = -94.396059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146177528, states[0] = -85.267754, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1155542614, states[0] = -94.407198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163754089, states[0] = -94.393581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174114669, states[0] = -94.398286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184724010, states[0] = -94.394241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195229804, states[0] = -94.393881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203891103, states[0] = -94.406854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213020211, states[0] = -94.401357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222871195, states[0] = -94.328211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232558095, states[0] = -94.399537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243209991, states[0] = -94.393792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253813498, states[0] = -94.390296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265301870, states[0] = -94.409407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275946271, states[0] = -94.403416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284829197, states[0] = -94.408077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294481551, states[0] = -94.385007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304433649, states[0] = -94.403493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314778602, states[0] = -94.409428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325092890, states[0] = -94.409303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336568494, states[0] = 18.897276, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1345603158, states[0] = 0.790569, states[40]= 0.000155
Saving checkpoint... 
Iteration: 1356107055, states[0] = -2.053832, states[40]= 0.000206
Saving checkpoint... 
Iteration: 1365005719, states[0] = 16.517029, states[40]= 0.022746
Saving checkpoint... 
Iteration: 1374258956, states[0] = -94.082441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382542536, states[0] = -94.397784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391658635, states[0] = -94.393239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401963870, states[0] = -94.400690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412514043, states[0] = -94.398458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422117032, states[0] = -11.013399, states[40]= 0.000265
Saving checkpoint... 
Iteration: 1432346424, states[0] = -94.386493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442785441, states[0] = -94.388175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454437387, states[0] = -94.400969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463429079, states[0] = -94.401174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473010528, states[0] = 21.627545, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1483419770, states[0] = -94.383625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493250012, states[0] = -94.407481, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.257255
 - CaMKt in component CaMK (millimolar): 0.003635
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 7.344647
 - nass in component intracellular_ions (millimolar): 7.344784
 - ki in component intracellular_ions (millimolar): 144.296202
 - kss in component intracellular_ions (millimolar): 144.296185
 - cansr in component intracellular_ions (millimolar): 2.440318
 - cajsr in component intracellular_ions (millimolar): 2.440950
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.003862
 - hf in component INa (dimensionless): 0.868357
 - hs in component INa (dimensionless): 0.868358
 - j in component INa (dimensionless): 0.868364
 - hsp in component INa (dimensionless): 0.704289
 - jp in component INa (dimensionless): 0.868367
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.711904
 - hLp in component INaL (dimensionless): 0.516386
 - a in component Ito (dimensionless): 0.000651
 - iF in component Ito (dimensionless): 0.999854
 - iS in component Ito (dimensionless): 0.999854
 - ap in component Ito (dimensionless): 0.000332
 - iFp in component Ito (dimensionless): 0.999854
 - iSp in component Ito (dimensionless): 0.999854
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.990958
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005106
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.024984
 - xs1 in component IKs (dimensionless): 0.069567
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997501
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:11:10 (1927): called boinc_finish(0)

</stderr_txt>
]]>


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