𝕏

Task 55268889

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_519_0
Workunit 26243583
Created 29 Jun 2024, 9:11:55 UTC
Sent 29 Jun 2024, 11:50:57 UTC
Report deadline 2 Jul 2024, 11:50:57 UTC
Received 2 Jul 2024, 16:41:14 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 235599
Run time 4 hours 27 min 55 sec
CPU time 3 hours 51 min 21 sec
Validate state Valid
Credit 45.08
Device peak FLOPS 3.09 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.85 MB
Peak swap size 6.39 MB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_519.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_519_0_r1360913149_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_519_0_r1360913149_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 113.811177
     * GNaL_b in INaL: 0.006263
     * Gto_b in Ito: 0.072596
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032781
     * GKs_b in IKs: 0.001800
     * GK1_b in IK1: 0.153128
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 73.681314
     * GKb_b in IKb: 0.003735
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027739
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7337930, states[0] = -94.175510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17602626, states[0] = -94.081604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23256943, states[0] = -94.066918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28800165, states[0] = -94.073565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34000392, states[0] = -45.094404, states[40]= 0.000010


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_519.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_519_0_r1360913149_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_519_0_r1360913149_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 113.811177
     * GNaL_b in INaL: 0.006263
     * Gto_b in Ito: 0.072596
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032781
     * GKs_b in IKs: 0.001800
     * GK1_b in IK1: 0.153128
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 73.681314
     * GKb_b in IKb: 0.003735
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027739
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 34000392
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -45.094404 (After loading)
 - states[40]: 0.000010 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 40935875, states[0] = -94.055016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51570855, states[0] = -94.028647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61403495, states[0] = -94.035106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67137171, states[0] = -94.046914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72704747, states[0] = -94.068905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78258264, states[0] = -93.663429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83905632, states[0] = -94.029267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89638746, states[0] = -94.036530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95257993, states[0] = -94.049883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100957893, states[0] = -94.065025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105787446, states[0] = -94.036767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110797127, states[0] = -94.075109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116527245, states[0] = -94.068895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122310648, states[0] = -93.863853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127842969, states[0] = -94.038824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133317650, states[0] = -94.053589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139021019, states[0] = -94.066929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143699567, states[0] = -94.043230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152009882, states[0] = 21.841590, states[40]= 0.000005
Saving checkpoint... 
Iteration: 157729050, states[0] = -94.043302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163499624, states[0] = -94.049402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169253267, states[0] = -94.057963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175010448, states[0] = -94.069058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180794109, states[0] = -94.080226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185704236, states[0] = -94.044578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191448785, states[0] = -94.051495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197058981, states[0] = -94.066937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202877779, states[0] = -94.076285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208637506, states[0] = -94.083724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214453060, states[0] = -94.048488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220170565, states[0] = -72.669154, states[40]= 0.000003
Saving checkpoint... 
Iteration: 225805562, states[0] = -94.042509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231498500, states[0] = -94.050043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237291453, states[0] = -94.056899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243096550, states[0] = -94.065084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248716361, states[0] = -94.083184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254479789, states[0] = -94.059826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260071902, states[0] = 17.858411, states[40]= 0.000003
Saving checkpoint... 
Iteration: 264965973, states[0] = -94.071407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270723777, states[0] = -94.082807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275641450, states[0] = -94.045871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286230847, states[0] = -93.518058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291747880, states[0] = -94.043238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295457023, states[0] = -94.050780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299762233, states[0] = -94.042847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305146979, states[0] = -94.062238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310773086, states[0] = -94.080659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316504179, states[0] = -94.066981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321632081, states[0] = -94.045647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327390598, states[0] = -94.052581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332907987, states[0] = -94.073781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338666269, states[0] = -94.083029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343541027, states[0] = -94.047820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349148450, states[0] = -94.061711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354964438, states[0] = -94.070584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360762587, states[0] = -94.080558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366538614, states[0] = -94.074005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372326092, states[0] = -93.902893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378014855, states[0] = 24.368094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383800441, states[0] = -94.041149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389474008, states[0] = -94.049267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395234014, states[0] = -94.057595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401034968, states[0] = -94.066492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406671159, states[0] = -94.082288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413561402, states[0] = -94.046501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420719510, states[0] = -94.081360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424914757, states[0] = -94.072431, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_519.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_519_0_r1360913149_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_519_0_r1360913149_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 113.811177
     * GNaL_b in INaL: 0.006263
     * Gto_b in Ito: 0.072596
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032781
     * GKs_b in IKs: 0.001800
     * GK1_b in IK1: 0.153128
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 73.681314
     * GKb_b in IKb: 0.003735
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027739
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 424914757
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.072431 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 432265839, states[0] = -93.710348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440477702, states[0] = -94.057134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446182864, states[0] = -89.730124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451935744, states[0] = -94.037813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457667502, states[0] = -94.043305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463459786, states[0] = -94.048892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469199206, states[0] = -94.058216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474954247, states[0] = -94.069810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479861153, states[0] = -94.038888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485504150, states[0] = -94.047325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491322463, states[0] = -94.053168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497114615, states[0] = -94.061629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502940125, states[0] = -94.070244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508420112, states[0] = -94.025502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514230887, states[0] = -93.515797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519949287, states[0] = -94.036829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525785262, states[0] = -94.039912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531571830, states[0] = -94.044927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535971980, states[0] = -94.036261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547893000, states[0] = -94.037539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557680690, states[0] = -94.041895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563394184, states[0] = -94.049892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568320371, states[0] = -93.887887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573956091, states[0] = -94.036118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579735363, states[0] = -94.040399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585310761, states[0] = -94.052566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591116934, states[0] = -94.060495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596796076, states[0] = -94.076552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602603727, states[0] = -94.078539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608311696, states[0] = -93.866217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614096066, states[0] = 5.308532, states[40]= 0.000061
Saving checkpoint... 
Iteration: 619275927, states[0] = -94.053500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625066150, states[0] = -94.062516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630621806, states[0] = -94.079088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636405718, states[0] = -94.012620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642189926, states[0] = -92.726591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645875048, states[0] = -94.036802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649523003, states[0] = -94.044986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653054669, states[0] = -94.062768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657447242, states[0] = -94.047155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658876997, states[0] = -94.071857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669932689, states[0] = -94.035478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677501438, states[0] = -94.045301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689536648, states[0] = -94.044162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700040212, states[0] = 26.931737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705762460, states[0] = -94.038425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711538972, states[0] = -94.043856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717283769, states[0] = -94.052129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721884616, states[0] = -94.035788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727161094, states[0] = -94.057026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732556565, states[0] = -94.072751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738054011, states[0] = 24.232848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743614885, states[0] = -94.041476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749417712, states[0] = -94.047085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754848886, states[0] = -94.072258, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_519.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_519_0_r1360913149_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_519_0_r1360913149_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 113.811177
     * GNaL_b in INaL: 0.006263
     * Gto_b in Ito: 0.072596
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032781
     * GKs_b in IKs: 0.001800
     * GK1_b in IK1: 0.153128
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 73.681314
     * GKb_b in IKb: 0.003735
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027739
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 754848886
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.072258 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 762137050, states[0] = -33.664453, states[40]= 0.000281
Saving checkpoint... 
Iteration: 770228355, states[0] = -93.495792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776028795, states[0] = 27.209148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781873613, states[0] = -94.035339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787615910, states[0] = -94.040968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793408565, states[0] = -94.046900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799230871, states[0] = -94.053303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805035114, states[0] = -94.062069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809906685, states[0] = -94.034414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815708227, states[0] = -94.038426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821468919, states[0] = -94.044692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827265038, states[0] = -94.051643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832889135, states[0] = -94.069321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840183351, states[0] = -90.112557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846110762, states[0] = -5.580258, states[40]= 0.000189
Saving checkpoint... 
Iteration: 851913054, states[0] = -94.033837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857706069, states[0] = -94.038016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863334151, states[0] = -94.048676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869128163, states[0] = -94.056941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874880899, states[0] = -94.069293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880654089, states[0] = -94.077073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886408566, states[0] = -94.012305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891380035, states[0] = -94.046775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896914990, states[0] = -94.067261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902735650, states[0] = -94.075619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908302300, states[0] = -93.837271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913928809, states[0] = -94.032872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919762144, states[0] = -94.036087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925472426, states[0] = -94.043447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931248371, states[0] = -94.051158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936447745, states[0] = -94.038204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942076244, states[0] = 15.922199, states[40]= 0.000006
Saving checkpoint... 
Iteration: 947787925, states[0] = -94.035231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953368857, states[0] = -94.046476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958984330, states[0] = -94.062958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964552519, states[0] = -94.069662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971022961, states[0] = -94.060861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979972210, states[0] = -94.031390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985753638, states[0] = -94.035548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991493631, states[0] = -94.042091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997247828, states[0] = -94.050457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003024836, states[0] = -94.060417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008627637, states[0] = -94.075161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014355071, states[0] = -93.949129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019999848, states[0] = -94.030486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025705051, states[0] = -94.036198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031459017, states[0] = -94.042695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037094507, states[0] = -94.056658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042219288, states[0] = -93.428062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047779097, states[0] = -94.034321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052706210, states[0] = -94.074785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058239699, states[0] = -93.565869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063998463, states[0] = -94.030027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069505823, states[0] = -94.040879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075138711, states[0] = -94.054211, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_519.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_519_0_r1360913149_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_519_0_r1360913149_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 113.811177
     * GNaL_b in INaL: 0.006263
     * Gto_b in Ito: 0.072596
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032781
     * GKs_b in IKs: 0.001800
     * GK1_b in IK1: 0.153128
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 73.681314
     * GKb_b in IKb: 0.003735
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027739
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1075138711
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.054211 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1082355838, states[0] = -93.949562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092823660, states[0] = -94.069827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099718722, states[0] = -94.035075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105072444, states[0] = -94.056964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110429274, states[0] = -94.025298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116184008, states[0] = -90.581203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121966508, states[0] = -94.029930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127445668, states[0] = -94.042057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133217998, states[0] = -94.050171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138876469, states[0] = -94.066640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144582078, states[0] = -94.071053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152911914, states[0] = -94.064626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163279812, states[0] = -94.047397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173804549, states[0] = -94.032409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181579238, states[0] = -94.037608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187138686, states[0] = -94.052987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192778298, states[0] = -94.070830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197503157, states[0] = -94.039555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202808110, states[0] = -94.069374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208309437, states[0] = -93.853680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213905348, states[0] = -94.030009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219616734, states[0] = -94.036214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225329498, states[0] = -94.044879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230900663, states[0] = -94.064366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236044155, states[0] = 26.400246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241668764, states[0] = -94.034685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247010573, states[0] = -94.058467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252718037, states[0] = -94.072317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258279539, states[0] = -93.757784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263976785, states[0] = -94.028198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268260699, states[0] = -93.677203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278259532, states[0] = -93.671480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284044482, states[0] = 26.347078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289745106, states[0] = -94.032403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294209746, states[0] = -93.351348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305984473, states[0] = -94.027607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315891258, states[0] = -94.029152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321507132, states[0] = -94.038081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327286588, states[0] = -94.045345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332892348, states[0] = -94.063689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338604544, states[0] = -94.070552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344405852, states[0] = -94.004980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349464172, states[0] = -94.039054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355193056, states[0] = -94.048780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360937504, states[0] = -94.061004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365688138, states[0] = -94.032866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371432417, states[0] = -94.039802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377223411, states[0] = -94.047280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382803838, states[0] = -94.067609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388465725, states[0] = -94.041934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394213918, states[0] = -93.383348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399884836, states[0] = -94.028352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405643880, states[0] = -94.033494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411368787, states[0] = -94.041464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417127431, states[0] = -94.050979, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_519.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_519_0_r1360913149_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_519_0_r1360913149_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 113.811177
     * GNaL_b in INaL: 0.006263
     * Gto_b in Ito: 0.072596
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032781
     * GKs_b in IKs: 0.001800
     * GK1_b in IK1: 0.153128
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 73.681314
     * GKb_b in IKb: 0.003735
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027739
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1417127431
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.050979 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1422616174, states[0] = -94.070216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434609224, states[0] = -94.069757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445260143, states[0] = -94.045069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452945979, states[0] = -94.059554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458518847, states[0] = -94.058167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464106085, states[0] = -1.612307, states[40]= 0.000149
Saving checkpoint... 
Iteration: 1469811429, states[0] = -94.029024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475476630, states[0] = -94.037296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481203415, states[0] = -94.046967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486984538, states[0] = -94.057175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492325070, states[0] = -93.888305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497618841, states[0] = -94.033114, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.901190
 - CaMKt in component CaMK (millimolar): 0.002324
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.107269
 - nass in component intracellular_ions (millimolar): 7.107405
 - ki in component intracellular_ions (millimolar): 144.579399
 - kss in component intracellular_ions (millimolar): 144.579385
 - cansr in component intracellular_ions (millimolar): 2.406906
 - cajsr in component intracellular_ions (millimolar): 2.407212
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.004003
 - hf in component INa (dimensionless): 0.861524
 - hs in component INa (dimensionless): 0.861524
 - j in component INa (dimensionless): 0.861528
 - hsp in component INa (dimensionless): 0.691958
 - jp in component INa (dimensionless): 0.861531
 - mL in component INaL (dimensionless): 0.000060
 - hL in component INaL (dimensionless): 0.702030
 - hLp in component INaL (dimensionless): 0.506862
 - a in component Ito (dimensionless): 0.000667
 - iF in component Ito (dimensionless): 0.999845
 - iS in component Ito (dimensionless): 0.999845
 - ap in component Ito (dimensionless): 0.000340
 - iFp in component Ito (dimensionless): 0.999845
 - iSp in component Ito (dimensionless): 0.999845
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996757
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005252
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.007078
 - xs1 in component IKs (dimensionless): 0.039105
 - xs2 in component IKs (dimensionless): 0.000098
 - xk1 in component IK1 (dimensionless): 0.997588
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:06:32 (2412): called boinc_finish(0)

</stderr_txt>
]]>


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