𝕏

Task 55268647

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_318_0
Workunit 26243462
Created 29 Jun 2024, 9:11:45 UTC
Sent 29 Jun 2024, 11:51:47 UTC
Report deadline 2 Jul 2024, 11:51:47 UTC
Received 30 Jun 2024, 11:36:21 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238614
Run time 2 hours 9 min 58 sec
CPU time 2 hours 9 min 19 sec
Validate state Valid
Credit 43.67
Device peak FLOPS 3.71 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.74 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_318.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_318_0_r988634649_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_318_0_r988634649_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 97.686633
     * GNaL_b in INaL: 0.007627
     * Gto_b in Ito: 0.089458
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.010136
     * GKs_b in IKs: 0.002121
     * GK1_b in IK1: 0.157166
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 66.023696
     * GKb_b in IKb: 0.003925
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034733
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10465878, states[0] = -94.906981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20229443, states[0] = -45.427468, states[40]= 0.000482
Saving checkpoint... 
Iteration: 30170816, states[0] = -22.388600, states[40]= 0.005143
Saving checkpoint... 
Iteration: 40163645, states[0] = -19.550396, states[40]= 0.004517
Saving checkpoint... 
Iteration: 50129097, states[0] = -4.573928, states[40]= 0.004018
Saving checkpoint... 
Iteration: 60059106, states[0] = 20.635870, states[40]= 0.003625
Saving checkpoint... 
Iteration: 70549802, states[0] = 23.410483, states[40]= 0.003034
Saving checkpoint... 
Iteration: 81054985, states[0] = 21.974538, states[40]= 0.003402
Saving checkpoint... 
Iteration: 90635188, states[0] = -6.562750, states[40]= 0.003557
Saving checkpoint... 
Iteration: 100932864, states[0] = -94.773509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111130911, states[0] = -4.545649, states[40]= 0.003981
Saving checkpoint... 
Iteration: 120886386, states[0] = -94.731261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130869232, states[0] = -94.710243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140719263, states[0] = -35.751939, states[40]= 0.001903
Saving checkpoint... 
Iteration: 151172854, states[0] = -21.146756, states[40]= 0.005153
Saving checkpoint... 
Iteration: 161272953, states[0] = -60.130279, states[40]= 0.000043
Saving checkpoint... 
Iteration: 171321109, states[0] = -94.607422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181709510, states[0] = -32.262818, states[40]= 0.002859
Saving checkpoint... 
Iteration: 192070912, states[0] = 17.387389, states[40]= 0.004405
Saving checkpoint... 
Iteration: 201737724, states[0] = -42.700260, states[40]= 0.000746
Saving checkpoint... 
Iteration: 211910302, states[0] = -94.748561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222466366, states[0] = -94.783558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233563983, states[0] = 19.520115, states[40]= 0.004038
Saving checkpoint... 
Iteration: 243819312, states[0] = -94.583496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253534122, states[0] = 27.963956, states[40]= 0.002361
Saving checkpoint... 
Iteration: 263822405, states[0] = -94.613631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274540229, states[0] = 26.341011, states[40]= 0.002613
Saving checkpoint... 
Iteration: 285146607, states[0] = -11.192800, states[40]= 0.002735
Saving checkpoint... 
Iteration: 295587856, states[0] = 11.841104, states[40]= 0.004986
Saving checkpoint... 
Iteration: 306223201, states[0] = -36.969459, states[40]= 0.001625
Saving checkpoint... 
Iteration: 316430922, states[0] = -94.763048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326926887, states[0] = -94.760260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336917718, states[0] = -94.753539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347125567, states[0] = -2.088225, states[40]= 0.004436
Saving checkpoint... 
Iteration: 357565024, states[0] = 19.211584, states[40]= 0.004099
Saving checkpoint... 
Iteration: 367302185, states[0] = -90.071207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377523356, states[0] = 30.217116, states[40]= 0.002542
Saving checkpoint... 
Iteration: 387236293, states[0] = -42.049236, states[40]= 0.000818
Saving checkpoint... 
Iteration: 397289699, states[0] = -73.521367, states[40]= 0.000004
Saving checkpoint... 
Iteration: 407072332, states[0] = 16.956028, states[40]= 0.004473
Saving checkpoint... 
Iteration: 417067142, states[0] = 18.568210, states[40]= 0.004216
Saving checkpoint... 
Iteration: 428570875, states[0] = 17.413808, states[40]= 0.004405
Saving checkpoint... 
Iteration: 438287654, states[0] = -71.288711, states[40]= 0.000006
Saving checkpoint... 
Iteration: 450106368, states[0] = 5.291427, states[40]= 0.005115
Saving checkpoint... 
Iteration: 460443689, states[0] = -94.770584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470039171, states[0] = 26.632363, states[40]= 0.002564
Saving checkpoint... 
Iteration: 480568509, states[0] = 18.148591, states[40]= 0.004288
Saving checkpoint... 
Iteration: 490670928, states[0] = -20.448606, states[40]= 0.004988
Saving checkpoint... 
Iteration: 500558614, states[0] = 21.115262, states[40]= 0.003714
Saving checkpoint... 
Iteration: 510472222, states[0] = -94.784951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520559563, states[0] = 20.837248, states[40]= 0.003773
Saving checkpoint... 
Iteration: 530293399, states[0] = -78.176894, states[40]= 0.000002
Saving checkpoint... 
Iteration: 541034175, states[0] = 27.953316, states[40]= 0.002364
Saving checkpoint... 
Iteration: 551225109, states[0] = -37.671912, states[40]= 0.001484
Saving checkpoint... 
Iteration: 562069866, states[0] = 17.728575, states[40]= 0.004356
Saving checkpoint... 
Iteration: 571996451, states[0] = -94.794201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582491630, states[0] = -94.792476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593201733, states[0] = -29.691979, states[40]= 0.003702
Saving checkpoint... 
Iteration: 603825258, states[0] = -94.627437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614033592, states[0] = 28.100571, states[40]= 0.002346
Saving checkpoint... 
Iteration: 623921896, states[0] = -94.755829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634286034, states[0] = -69.672870, states[40]= 0.000008
Saving checkpoint... 
Iteration: 644634918, states[0] = -6.031153, states[40]= 0.003651
Saving checkpoint... 
Iteration: 654620005, states[0] = 0.137800, states[40]= 0.004759
Saving checkpoint... 
Iteration: 665419328, states[0] = -94.753808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675832461, states[0] = -94.647229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685900496, states[0] = -94.738127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696383143, states[0] = -94.720729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706640617, states[0] = -8.536491, states[40]= 0.003132
Saving checkpoint... 
Iteration: 717238610, states[0] = -43.007293, states[40]= 0.000713
Saving checkpoint... 
Iteration: 727513312, states[0] = 30.514244, states[40]= 0.016430
Saving checkpoint... 
Iteration: 737906424, states[0] = -94.743231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748303270, states[0] = -91.050279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758843906, states[0] = -94.667595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769038991, states[0] = 26.681626, states[40]= 0.002556
Saving checkpoint... 
Iteration: 779287028, states[0] = -70.646686, states[40]= 0.000007
Saving checkpoint... 
Iteration: 790028930, states[0] = 29.196382, states[40]= 0.002256
Saving checkpoint... 
Iteration: 800222328, states[0] = -36.645005, states[40]= 0.001694
Saving checkpoint... 
Iteration: 810463288, states[0] = -94.780009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821147008, states[0] = -11.364063, states[40]= 0.002719
Saving checkpoint... 
Iteration: 831928445, states[0] = -94.759881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842350329, states[0] = -94.677552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852635262, states[0] = -6.180462, states[40]= 0.003619
Saving checkpoint... 
Iteration: 863316735, states[0] = -94.528985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873677360, states[0] = -22.414332, states[40]= 0.005287
Saving checkpoint... 
Iteration: 884218851, states[0] = -35.393263, states[40]= 0.001981
Saving checkpoint... 
Iteration: 894908445, states[0] = -94.744507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905128202, states[0] = -3.172329, states[40]= 0.004241
Saving checkpoint... 
Iteration: 915631604, states[0] = -4.604550, states[40]= 0.003955
Saving checkpoint... 
Iteration: 926291708, states[0] = -75.941182, states[40]= 0.000003
Saving checkpoint... 
Iteration: 936551880, states[0] = 23.061011, states[40]= 0.003284
Saving checkpoint... 
Iteration: 947384059, states[0] = -94.721020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957718231, states[0] = -35.173578, states[40]= 0.002035
Saving checkpoint... 
Iteration: 968962970, states[0] = -94.779412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979328022, states[0] = -94.635747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990014133, states[0] = 30.592883, states[40]= 0.012933
Saving checkpoint... 
Iteration: 1000473389, states[0] = -94.784086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011041261, states[0] = 26.058528, states[40]= 0.002665
Saving checkpoint... 
Iteration: 1021346970, states[0] = -94.671803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031502474, states[0] = 41.708689, states[40]= 0.382684
Saving checkpoint... 
Iteration: 1041736815, states[0] = -42.261995, states[40]= 0.000793
Saving checkpoint... 
Iteration: 1051795754, states[0] = -81.519461, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1062119880, states[0] = 0.187310, states[40]= 0.004765
Saving checkpoint... 
Iteration: 1072729777, states[0] = -39.447967, states[40]= 0.001173
Saving checkpoint... 
Iteration: 1083078920, states[0] = 14.836922, states[40]= 0.004737
Saving checkpoint... 
Iteration: 1093215677, states[0] = -34.279924, states[40]= 0.002266
Saving checkpoint... 
Iteration: 1103204366, states[0] = -30.523092, states[40]= 0.003421
Saving checkpoint... 
Iteration: 1113622552, states[0] = -0.869764, states[40]= 0.004626
Saving checkpoint... 
Iteration: 1123952931, states[0] = -94.773888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134531201, states[0] = 28.683211, states[40]= 0.002284
Saving checkpoint... 
Iteration: 1145104073, states[0] = 6.128521, states[40]= 0.005129
Saving checkpoint... 
Iteration: 1155601457, states[0] = 7.073206, states[40]= 0.005134
Saving checkpoint... 
Iteration: 1166113097, states[0] = 2.793639, states[40]= 0.005005
Saving checkpoint... 
Iteration: 1176304421, states[0] = -91.904396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186595318, states[0] = 9.255786, states[40]= 0.005101
Saving checkpoint... 
Iteration: 1197092753, states[0] = 10.153552, states[40]= 0.005071
Saving checkpoint... 
Iteration: 1207679584, states[0] = -23.075419, states[40]= 0.005281
Saving checkpoint... 
Iteration: 1217807919, states[0] = -93.521128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228120707, states[0] = -0.137655, states[40]= 0.004725
Saving checkpoint... 
Iteration: 1238301708, states[0] = -89.567926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249522184, states[0] = 30.374364, states[40]= 0.002760
Saving checkpoint... 
Iteration: 1260203041, states[0] = -30.102545, states[40]= 0.003563
Saving checkpoint... 
Iteration: 1270162289, states[0] = -17.560436, states[40]= 0.003757
Saving checkpoint... 
Iteration: 1280592360, states[0] = 10.290423, states[40]= 0.005065
Saving checkpoint... 
Iteration: 1290575818, states[0] = 15.845263, states[40]= 0.004622
Saving checkpoint... 
Iteration: 1301174911, states[0] = -21.676501, states[40]= 0.005236
Saving checkpoint... 
Iteration: 1311792083, states[0] = -76.416822, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1322202115, states[0] = -29.810927, states[40]= 0.003661
Saving checkpoint... 
Iteration: 1332642929, states[0] = -9.561081, states[40]= 0.002950
Saving checkpoint... 
Iteration: 1342944422, states[0] = -94.768534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353167166, states[0] = -19.237259, states[40]= 0.004540
Saving checkpoint... 
Iteration: 1363822486, states[0] = -94.610639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374048373, states[0] = 24.060619, states[40]= 0.003064
Saving checkpoint... 
Iteration: 1384658988, states[0] = -16.338065, states[40]= 0.003252
Saving checkpoint... 
Iteration: 1395053825, states[0] = 22.503622, states[40]= 0.003408
Saving checkpoint... 
Iteration: 1405217455, states[0] = -34.899675, states[40]= 0.002104
Saving checkpoint... 
Iteration: 1416128542, states[0] = -3.313258, states[40]= 0.004214
Saving checkpoint... 
Iteration: 1426370083, states[0] = -94.703366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436618534, states[0] = 0.713255, states[40]= 0.004825
Saving checkpoint... 
Iteration: 1446948842, states[0] = -94.770755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457650331, states[0] = -12.807186, states[40]= 0.002655
Saving checkpoint... 
Iteration: 1467936013, states[0] = -94.763079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478529245, states[0] = 29.128448, states[40]= 0.002258
Saving checkpoint... 
Iteration: 1488875334, states[0] = -94.709597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499050396, states[0] = 23.485222, states[40]= 0.003190
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.668673
 - CaMKt in component CaMK (millimolar): 0.015888
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.427754
 - nass in component intracellular_ions (millimolar): 6.427835
 - ki in component intracellular_ions (millimolar): 145.478728
 - kss in component intracellular_ions (millimolar): 145.478717
 - cansr in component intracellular_ions (millimolar): 1.591834
 - cajsr in component intracellular_ions (millimolar): 1.523058
 - cai in component intracellular_ions (millimolar): 0.000086
 - m in component INa (dimensionless): 0.003705
 - hf in component INa (dimensionless): 0.875896
 - hs in component INa (dimensionless): 0.875882
 - j in component INa (dimensionless): 0.875795
 - hsp in component INa (dimensionless): 0.718088
 - jp in component INa (dimensionless): 0.875682
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.632408
 - hLp in component INaL (dimensionless): 0.320755
 - a in component Ito (dimensionless): 0.000633
 - iF in component Ito (dimensionless): 0.999864
 - iS in component Ito (dimensionless): 0.468424
 - ap in component Ito (dimensionless): 0.000323
 - iFp in component Ito (dimensionless): 0.999864
 - iSp in component Ito (dimensionless): 0.521090
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.847908
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999009
 - jca in component ICaL (dimensionless): 0.999828
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002707
 - xrf in component IKr (dimensionless): 0.000006
 - xrs in component IKr (dimensionless): 0.523561
 - xs1 in component IKs (dimensionless): 0.367879
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997398
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:35:09 (90533): called boinc_finish(0)

</stderr_txt>
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