𝕏

Task 55264232

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_811_0
Workunit 26241260
Created 29 Jun 2024, 9:09:13 UTC
Sent 29 Jun 2024, 11:04:44 UTC
Report deadline 2 Jul 2024, 11:04:44 UTC
Received 29 Jun 2024, 19:27:00 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 40 min 42 sec
CPU time 1 hours 37 min 32 sec
Validate state Valid
Credit 42.71
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.74 MB
Peak swap size 4.13 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_811.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_811_0_r271795622_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_EPI_4000-conf_811_0_r271795622_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.284514
     * GNaL_b in INaL: 0.004948
     * Gto_b in Ito: 0.095684
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030623
     * GKs_b in IKs: 0.002147
     * GK1_b in IK1: 0.160781
     * Gncx_b in INaCa_i: 0.000975
     * Pnak_b in INaK: 65.824072
     * GKb_b in IKb: 0.003710
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019772
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11778327, states[0] = -94.204495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23793610, states[0] = -94.143255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35885596, states[0] = -94.118577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48863089, states[0] = -94.146219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60924180, states[0] = -94.147272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73360265, states[0] = -94.135201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85836677, states[0] = -94.128936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98283707, states[0] = -93.871037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110884405, states[0] = -94.167830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123361444, states[0] = -94.150615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136096402, states[0] = 6.725025, states[40]= 0.000108
Saving checkpoint... 
Iteration: 149309508, states[0] = -94.155356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161898575, states[0] = -94.141832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173975562, states[0] = -94.141094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186452874, states[0] = -94.144605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199469039, states[0] = -94.152242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211675306, states[0] = -94.147199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224782667, states[0] = -94.179536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237560941, states[0] = -94.149820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249997558, states[0] = -94.141181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262311402, states[0] = -93.966164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273941240, states[0] = -94.141815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286523282, states[0] = -94.168657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299152807, states[0] = -94.162351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311537533, states[0] = -94.149620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324762834, states[0] = -94.179203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336449402, states[0] = -94.141851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349807911, states[0] = -94.143136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362832676, states[0] = -94.175935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375416022, states[0] = -94.152104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388022162, states[0] = 23.776949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400049753, states[0] = 24.382101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412510494, states[0] = -94.163895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424841981, states[0] = -94.174649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437577241, states[0] = -94.146855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450580428, states[0] = -94.175109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463482361, states[0] = -94.148955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476270057, states[0] = -93.826121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488867939, states[0] = -94.172560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501513569, states[0] = -94.147567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514268232, states[0] = -93.817802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526169046, states[0] = -63.239001, states[40]= 0.000030
Saving checkpoint... 
Iteration: 539424488, states[0] = -94.149517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552492358, states[0] = -94.156681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565482602, states[0] = -94.147490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579894932, states[0] = -94.138315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592425098, states[0] = -94.123429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607636127, states[0] = -94.143028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622218723, states[0] = -93.531657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637160636, states[0] = -94.157262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657670042, states[0] = -94.141549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671652848, states[0] = -94.141731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688222610, states[0] = -93.558475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704805146, states[0] = -94.172241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721250506, states[0] = -94.152630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735131492, states[0] = -94.157053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747152312, states[0] = -94.156027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760411059, states[0] = -94.110438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772750772, states[0] = -94.173226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785971422, states[0] = -94.134129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799171675, states[0] = -94.154507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812595267, states[0] = -94.171230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824509016, states[0] = -94.157645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836709863, states[0] = -94.173293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849362613, states[0] = -94.146990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862622787, states[0] = -94.172136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875984391, states[0] = -94.132643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887907602, states[0] = -94.133696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900362187, states[0] = -94.055223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912775462, states[0] = -94.170413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925521119, states[0] = -94.141309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938103800, states[0] = 2.167794, states[40]= 0.000223
Saving checkpoint... 
Iteration: 950483487, states[0] = -94.148010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962804794, states[0] = -94.168580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975190945, states[0] = -94.151247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988239133, states[0] = -93.661832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998863882, states[0] = -94.165484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009388849, states[0] = -94.143890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019194438, states[0] = -94.150487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029378471, states[0] = -94.143929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039900134, states[0] = -94.131660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050930830, states[0] = -94.161599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062286534, states[0] = -93.880521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074079490, states[0] = 15.000224, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1085550298, states[0] = -94.138278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096234826, states[0] = -93.633788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107646232, states[0] = -94.135660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117671908, states[0] = -94.134944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126805247, states[0] = -94.166229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137881060, states[0] = -94.130584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148517265, states[0] = -94.155089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159594984, states[0] = -94.136118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171809400, states[0] = -94.131382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183025683, states[0] = -94.155282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193865357, states[0] = -94.130054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204681523, states[0] = -94.168333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214955315, states[0] = -94.158100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225100253, states[0] = -94.151383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236332174, states[0] = -93.999514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246890874, states[0] = -94.160696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257282809, states[0] = -94.143838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267738319, states[0] = -94.131401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277231371, states[0] = -94.145406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287414489, states[0] = -94.139144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297564623, states[0] = -94.134891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306559914, states[0] = -94.160564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316818680, states[0] = -94.162962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326091823, states[0] = 9.075083, states[40]= 0.000067
Saving checkpoint... 
Iteration: 1335397123, states[0] = -94.138980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345887398, states[0] = -94.127499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356769103, states[0] = -94.164319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368609593, states[0] = -94.164272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380089105, states[0] = 10.469766, states[40]= 0.000049
Saving checkpoint... 
Iteration: 1390816135, states[0] = -94.162017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401903585, states[0] = -94.126428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412384017, states[0] = -94.075324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423067579, states[0] = -94.149979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434021441, states[0] = 23.617711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444165177, states[0] = -58.890222, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1455337035, states[0] = -94.139169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467217843, states[0] = -94.143196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479182673, states[0] = -94.144377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490243597, states[0] = -93.680636, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.999462
 - CaMKt in component CaMK (millimolar): 0.002428
 - cass in component intracellular_ions (millimolar): 0.000103
 - nai in component intracellular_ions (millimolar): 7.350528
 - nass in component intracellular_ions (millimolar): 7.350672
 - ki in component intracellular_ions (millimolar): 144.295260
 - kss in component intracellular_ions (millimolar): 144.295244
 - cansr in component intracellular_ions (millimolar): 2.483057
 - cajsr in component intracellular_ions (millimolar): 2.483729
 - cai in component intracellular_ions (millimolar): 0.000108
 - m in component INa (dimensionless): 0.003964
 - hf in component INa (dimensionless): 0.863439
 - hs in component INa (dimensionless): 0.863439
 - j in component INa (dimensionless): 0.863443
 - hsp in component INa (dimensionless): 0.695389
 - jp in component INa (dimensionless): 0.863445
 - mL in component INaL (dimensionless): 0.000059
 - hL in component INaL (dimensionless): 0.704763
 - hLp in component INaL (dimensionless): 0.510098
 - a in component Ito (dimensionless): 0.000663
 - iF in component Ito (dimensionless): 0.999847
 - iS in component Ito (dimensionless): 0.999847
 - ap in component Ito (dimensionless): 0.000338
 - iFp in component Ito (dimensionless): 0.999847
 - iSp in component Ito (dimensionless): 0.999847
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996782
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005803
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.006716
 - xs1 in component IKs (dimensionless): 0.040016
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997564
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:57:54 (87078): called boinc_finish(0)

</stderr_txt>
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