𝕏

Task 55258178

Name HuVeMOp_20240626064103635658_ORdGradInc_k_24-Drouin_EPI_4000-conf_170_2
Workunit 26013134
Created 29 Jun 2024, 7:05:58 UTC
Sent 29 Jun 2024, 10:11:48 UTC
Report deadline 2 Jul 2024, 10:11:48 UTC
Received 1 Jul 2024, 9:48:12 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241675
Run time 4 hours 40 min 40 sec
CPU time 2 hours 19 min 3 sec
Validate state Valid
Credit 41.93
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.46 MB
Peak swap size 32.57 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Drouin_EPI_4000-conf_170.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Drouin_EPI_4000-conf_170_2_r1476931181_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Drouin_EPI_4000-conf_170_2_r1476931181_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.984066
     * GNaL_b in INaL: 0.007806
     * Gto_b in Ito: 0.088325
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.034108
     * GKs_b in IKs: 0.001772
     * GK1_b in IK1: 0.165216
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.977250
     * GKb_b in IKb: 0.004004
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.041921
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9579331, states[0] = -94.355856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22250066, states[0] = -93.923703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33942701, states[0] = -94.253417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48175521, states[0] = -80.524316, states[40]= 0.000001
Saving checkpoint... 
Iteration: 62043802, states[0] = 25.920058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75246802, states[0] = -94.266047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85840865, states[0] = -94.254626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99679903, states[0] = -94.260927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109825857, states[0] = -94.260093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119927947, states[0] = -94.259907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130103931, states[0] = 0.623923, states[40]= 0.000165
Saving checkpoint... 
Iteration: 143582738, states[0] = -94.268584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158076819, states[0] = 15.750062, states[40]= 0.000008
Saving checkpoint... 
Iteration: 172613077, states[0] = -94.299122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187123457, states[0] = -94.283886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201087775, states[0] = -94.285391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215858679, states[0] = -94.264685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231187136, states[0] = -94.281511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241202250, states[0] = -94.280896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251390330, states[0] = -94.274774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262214174, states[0] = -93.677469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276563659, states[0] = -94.295173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290877824, states[0] = -94.293839, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Drouin_EPI_4000-conf_170.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Drouin_EPI_4000-conf_170_2_r1476931181_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Drouin_EPI_4000-conf_170_2_r1476931181_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.984066
     * GNaL_b in INaL: 0.007806
     * Gto_b in Ito: 0.088325
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.034108
     * GKs_b in IKs: 0.001772
     * GK1_b in IK1: 0.165216
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.977250
     * GKb_b in IKb: 0.004004
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.041921
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 290877824
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.293839 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 318974369, states[0] = -94.289231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320044747, states[0] = 25.516167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329514421, states[0] = -94.270596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338541548, states[0] = -94.291519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351014796, states[0] = -94.287076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362440688, states[0] = -94.260125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375120372, states[0] = -94.282431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387508860, states[0] = -94.270002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399996018, states[0] = -94.260590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410524049, states[0] = -94.287572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421745027, states[0] = -94.264434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433477001, states[0] = -94.270223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445193864, states[0] = -94.278773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457104700, states[0] = -94.282002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468290549, states[0] = -94.047548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480234330, states[0] = -93.805902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491491461, states[0] = -94.269112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501521080, states[0] = -94.268245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508852984, states[0] = -94.292182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517417985, states[0] = -94.270733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524330590, states[0] = -94.142161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529448925, states[0] = -94.269737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535987702, states[0] = -94.258973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542456970, states[0] = -94.265658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550035706, states[0] = 26.147990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559164672, states[0] = -94.278390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567102907, states[0] = -94.280670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577434736, states[0] = -94.269503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587505093, states[0] = -94.267541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598555874, states[0] = -94.290208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608090210, states[0] = 9.030220, states[40]= 0.000043
Saving checkpoint... 
Iteration: 614306683, states[0] = -94.089633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624764236, states[0] = -94.294129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635369140, states[0] = -94.270617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645347677, states[0] = -94.271130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654522958, states[0] = -94.284250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659669576, states[0] = -94.262883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666952610, states[0] = -94.285770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675516803, states[0] = -94.266129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684483324, states[0] = -94.273768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693788074, states[0] = -94.260164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703839062, states[0] = -94.259145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713232849, states[0] = -94.273973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722287316, states[0] = -94.034368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731296382, states[0] = -94.271626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736557949, states[0] = -94.288705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742212783, states[0] = -93.661268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747625816, states[0] = -94.262680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750790284, states[0] = -94.291619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756703712, states[0] = -94.293923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759683185, states[0] = -94.261322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759926108, states[0] = -94.257019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765483508, states[0] = -94.265811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773013581, states[0] = -94.281743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781159457, states[0] = -94.275747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787401584, states[0] = -94.267738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796350679, states[0] = -94.171941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806454426, states[0] = -94.261156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806969053, states[0] = -94.283253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815728896, states[0] = -94.259704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818880515, states[0] = -94.287031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819525571, states[0] = -94.264070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823069977, states[0] = -94.278736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829368300, states[0] = -94.268167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833611127, states[0] = -94.261907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836510689, states[0] = -94.279315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841561129, states[0] = -94.262942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843701822, states[0] = -94.259879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845466402, states[0] = -94.265237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846910050, states[0] = -94.285368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848084162, states[0] = 12.212279, states[40]= 0.000021
Saving checkpoint... 
Iteration: 848488612, states[0] = -94.273322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853963230, states[0] = -94.255261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862206346, states[0] = -93.612034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872192031, states[0] = -93.442770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883687422, states[0] = -94.259655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893874269, states[0] = -94.256130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904041205, states[0] = 25.902466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914243938, states[0] = -93.853679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929149355, states[0] = -94.274245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943952853, states[0] = -94.254266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959841618, states[0] = -94.255832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975691514, states[0] = -94.258399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990925361, states[0] = -94.282849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006562702, states[0] = -94.285827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022431872, states[0] = -94.246810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037045529, states[0] = -94.277020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052563797, states[0] = -94.285364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065518776, states[0] = -94.261094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080542906, states[0] = -94.282275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094898081, states[0] = -94.282738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109512106, states[0] = -94.260701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123598881, states[0] = -94.258473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137685752, states[0] = -94.256442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152471125, states[0] = -94.263580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168204764, states[0] = -93.595775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183054632, states[0] = -94.274775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198309799, states[0] = -94.089655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214314003, states[0] = -94.099207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229089123, states[0] = -94.272773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243749110, states[0] = -94.253850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259134984, states[0] = -94.270582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276200351, states[0] = -93.558070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292790943, states[0] = -94.284687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308281734, states[0] = -94.008748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324212292, states[0] = -93.650012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340427215, states[0] = -94.239958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356138655, states[0] = -35.071892, states[40]= 0.000338
Saving checkpoint... 
Iteration: 1371245469, states[0] = -94.265136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387625468, states[0] = -94.254509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404273849, states[0] = -93.979845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419497675, states[0] = -94.257097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434509833, states[0] = -94.271489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449964819, states[0] = -94.247613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464644109, states[0] = -94.284870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477629009, states[0] = -94.253279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489808803, states[0] = -94.249614, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.122432
 - CaMKt in component CaMK (millimolar): 0.002348
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.188726
 - nass in component intracellular_ions (millimolar): 7.188865
 - ki in component intracellular_ions (millimolar): 144.478026
 - kss in component intracellular_ions (millimolar): 144.478011
 - cansr in component intracellular_ions (millimolar): 2.431292
 - cajsr in component intracellular_ions (millimolar): 2.431799
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.003915
 - hf in component INa (dimensionless): 0.865804
 - hs in component INa (dimensionless): 0.865804
 - j in component INa (dimensionless): 0.865808
 - hsp in component INa (dimensionless): 0.699652
 - jp in component INa (dimensionless): 0.865810
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.708166
 - hLp in component INaL (dimensionless): 0.514218
 - a in component Ito (dimensionless): 0.000657
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.999851
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.999851
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996822
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005408
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.006556
 - xs1 in component IKs (dimensionless): 0.039094
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997534
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:47:08 (17026): called boinc_finish(0)

</stderr_txt>
]]>


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