𝕏

Task 55258061

Name HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_673_2
Workunit 26043047
Created 29 Jun 2024, 6:46:52 UTC
Sent 29 Jun 2024, 10:10:48 UTC
Report deadline 2 Jul 2024, 19:46:48 UTC
Received 2 Jul 2024, 17:46:27 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236758
Run time 2 hours 36 min 15 sec
CPU time 2 hours 33 min 10 sec
Validate state Valid
Credit 60.71
Device peak FLOPS 3.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 6.97 MB
Peak swap size 1.45 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_673.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_673_2_r639810733_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_673_2_r639810733_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 114.202699
     * GNaL_b in INaL: 0.008743
     * Gto_b in Ito: 0.068453
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032322
     * GKs_b in IKs: 0.001859
     * GK1_b in IK1: 0.160881
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 67.648112
     * GKb_b in IKb: 0.003784
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038289
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14458979, states[0] = -95.096536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29096495, states[0] = -14.006305, states[40]= 0.001642
Saving checkpoint... 
Iteration: 43719986, states[0] = -94.904120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58292878, states[0] = -94.981792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72826728, states[0] = -94.999457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87439077, states[0] = -95.035510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102028732, states[0] = 21.089852, states[40]= 0.006996
Saving checkpoint... 
Iteration: 116640056, states[0] = -54.753281, states[40]= 0.000014
Saving checkpoint... 
Iteration: 130989317, states[0] = -95.038687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145580800, states[0] = -0.621820, states[40]= 0.004247
Saving checkpoint... 
Iteration: 160139930, states[0] = -54.433918, states[40]= 0.000015
Saving checkpoint... 
Iteration: 174807748, states[0] = -94.977768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189408018, states[0] = -95.022085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202620011, states[0] = -33.539595, states[40]= 0.000338
Saving checkpoint... 
Iteration: 217169454, states[0] = -93.402427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231653544, states[0] = -71.811386, states[40]= 0.000001
Saving checkpoint... 
Iteration: 246239897, states[0] = -94.909494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260709933, states[0] = -94.862134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275163017, states[0] = -87.532376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289691563, states[0] = -94.826707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304189567, states[0] = -94.821662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318699817, states[0] = -94.843538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333144119, states[0] = -59.313325, states[40]= 0.000006
Saving checkpoint... 
Iteration: 347635387, states[0] = -49.189188, states[40]= 0.000035
Saving checkpoint... 
Iteration: 362140784, states[0] = -55.359500, states[40]= 0.000013
Saving checkpoint... 
Iteration: 376641623, states[0] = -56.342537, states[40]= 0.000011
Saving checkpoint... 
Iteration: 391122124, states[0] = -35.523322, states[40]= 0.000262
Saving checkpoint... 
Iteration: 404963231, states[0] = -95.033051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419517021, states[0] = 24.299002, states[40]= 0.015123
Saving checkpoint... 
Iteration: 434046191, states[0] = 14.962904, states[40]= 0.005399
Saving checkpoint... 
Iteration: 448576457, states[0] = 1.823315, states[40]= 0.004566
Saving checkpoint... 
Iteration: 463070344, states[0] = 4.866580, states[40]= 0.004847
Saving checkpoint... 
Iteration: 477545042, states[0] = 15.402407, states[40]= 0.005439
Saving checkpoint... 
Iteration: 492064368, states[0] = 7.578133, states[40]= 0.005017
Saving checkpoint... 
Iteration: 506545754, states[0] = 15.130446, states[40]= 0.005414
Saving checkpoint... 
Iteration: 521066132, states[0] = 6.799054, states[40]= 0.004974
Saving checkpoint... 
Iteration: 535574621, states[0] = 2.773254, states[40]= 0.004666
Saving checkpoint... 
Iteration: 549925174, states[0] = -95.025758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564478141, states[0] = -95.035161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578911365, states[0] = -95.022417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593300490, states[0] = -94.971793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606979174, states[0] = -95.035280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621527368, states[0] = 21.559560, states[40]= 0.007309
Saving checkpoint... 
Iteration: 635907131, states[0] = -95.021279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650375957, states[0] = -95.011592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664851153, states[0] = -95.001552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679269631, states[0] = -94.944663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693742779, states[0] = -94.913112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708115154, states[0] = -29.011046, states[40]= 0.000557
Saving checkpoint... 
Iteration: 722606963, states[0] = -21.519881, states[40]= 0.000917
Saving checkpoint... 
Iteration: 737055898, states[0] = 11.135302, states[40]= 0.005179
Saving checkpoint... 
Iteration: 751513919, states[0] = 25.052732, states[40]= 0.024373
Saving checkpoint... 
Iteration: 765983388, states[0] = -95.035758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780439961, states[0] = -95.028755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794992097, states[0] = -95.036830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808560609, states[0] = 9.190042, states[40]= 0.005095
Saving checkpoint... 
Iteration: 823048067, states[0] = 14.238771, states[40]= 0.005343
Saving checkpoint... 
Iteration: 837539960, states[0] = 17.304307, states[40]= 0.005685
Saving checkpoint... 
Iteration: 852053824, states[0] = 11.970833, states[40]= 0.005216
Saving checkpoint... 
Iteration: 866546976, states[0] = 14.660906, states[40]= 0.005374
Saving checkpoint... 
Iteration: 881086234, states[0] = -4.003537, states[40]= 0.003648
Saving checkpoint... 
Iteration: 895606325, states[0] = -20.937832, states[40]= 0.000948
Saving checkpoint... 
Iteration: 910090404, states[0] = -7.025276, states[40]= 0.003004
Saving checkpoint... 
Iteration: 924637019, states[0] = -51.025825, states[40]= 0.000026
Saving checkpoint... 
Iteration: 938951704, states[0] = -95.030857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953451186, states[0] = -95.030758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967894429, states[0] = -95.017505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982380557, states[0] = -95.013036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996817081, states[0] = -94.983022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010274863, states[0] = -94.949703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024717009, states[0] = -94.873946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039203354, states[0] = -94.849776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053686221, states[0] = -94.809930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067887811, states[0] = -95.015398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082352932, states[0] = -95.002140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096827129, states[0] = -94.989035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111235463, states[0] = -94.902744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125767860, states[0] = -94.942607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140128638, states[0] = -41.943135, states[40]= 0.000105
Saving checkpoint... 
Iteration: 1154550614, states[0] = 13.243850, states[40]= 0.005280
Saving checkpoint... 
Iteration: 1169056107, states[0] = 11.050531, states[40]= 0.005175
Saving checkpoint... 
Iteration: 1183545123, states[0] = 15.371628, states[40]= 0.005436
Saving checkpoint... 
Iteration: 1198076203, states[0] = 1.956998, states[40]= 0.004581
Saving checkpoint... 
Iteration: 1211862297, states[0] = -95.006075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226381093, states[0] = -95.013095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240769853, states[0] = -94.944602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255336410, states[0] = -94.994048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269838523, states[0] = -94.995137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284262133, states[0] = -94.936387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298731354, states[0] = -94.896628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313216057, states[0] = -94.872186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327721823, states[0] = -94.881759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342175084, states[0] = -94.545518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356622218, states[0] = -35.612478, states[40]= 0.000259
Saving checkpoint... 
Iteration: 1371082846, states[0] = -1.808546, states[40]= 0.004056
Saving checkpoint... 
Iteration: 1385569739, states[0] = 5.151343, states[40]= 0.004868
Saving checkpoint... 
Iteration: 1400123382, states[0] = -36.728043, states[40]= 0.000222
Saving checkpoint... 
Iteration: 1413637169, states[0] = -51.195725, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1428191995, states[0] = -94.827101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442680909, states[0] = -94.766696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457206064, states[0] = -94.854527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471735943, states[0] = -94.903247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486151279, states[0] = -68.512773, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1500682651, states[0] = -10.619301, states[40]= 0.002410
Saving checkpoint... 
Iteration: 1514865090, states[0] = -95.087201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1529397804, states[0] = -95.291209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543864275, states[0] = 1.357212, states[40]= 0.005084
Saving checkpoint... 
Iteration: 1558347134, states[0] = -93.875254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572863955, states[0] = -95.287132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1587332181, states[0] = 17.968286, states[40]= 0.007404
Saving checkpoint... 
Iteration: 1601720159, states[0] = 22.863277, states[40]= 0.012236
Saving checkpoint... 
Iteration: 1615236026, states[0] = 16.169770, states[40]= 0.006896
Saving checkpoint... 
Iteration: 1629710532, states[0] = -44.629291, states[40]= 0.000073
Saving checkpoint... 
Iteration: 1644202957, states[0] = -95.215497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1658689257, states[0] = -95.314042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673180183, states[0] = -12.352611, states[40]= 0.002157
Saving checkpoint... 
Iteration: 1687624510, states[0] = -62.557063, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1702126630, states[0] = -95.252808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1716572738, states[0] = -95.301976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1731039456, states[0] = 14.506833, states[40]= 0.006566
Saving checkpoint... 
Iteration: 1745373022, states[0] = -95.302234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1759875680, states[0] = -7.999439, states[40]= 0.003157
Saving checkpoint... 
Iteration: 1774408050, states[0] = -95.224871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1788783826, states[0] = -95.179010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803042832, states[0] = 15.288080, states[40]= 0.005595
Saving checkpoint... 
Iteration: 1816986631, states[0] = -95.077408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1831438414, states[0] = -95.055866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845926597, states[0] = -95.043775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1860350932, states[0] = -95.012889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874794676, states[0] = -94.974586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1889299715, states[0] = -94.975724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1903780888, states[0] = -94.958302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918266723, states[0] = -94.943228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932741900, states[0] = -94.912742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1947170278, states[0] = -93.723376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1961612649, states[0] = -26.748742, states[40]= 0.000672
Saving checkpoint... 
Iteration: 1976067436, states[0] = 6.202786, states[40]= 0.004939
Saving checkpoint... 
Iteration: 1990493104, states[0] = -95.036573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004676196, states[0] = -94.621542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2018482981, states[0] = -95.035145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2032916939, states[0] = -95.023107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047383660, states[0] = -95.013551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2061805579, states[0] = -94.974744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2076255422, states[0] = -94.928297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2090897683, states[0] = -95.017868, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.912918
 - CaMKt in component CaMK (millimolar): 0.006811
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.658347
 - nass in component intracellular_ions (millimolar): 6.658407
 - ki in component intracellular_ions (millimolar): 145.322313
 - kss in component intracellular_ions (millimolar): 145.322293
 - cansr in component intracellular_ions (millimolar): 1.304173
 - cajsr in component intracellular_ions (millimolar): 1.266015
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003614
 - hf in component INa (dimensionless): 0.880193
 - hs in component INa (dimensionless): 0.880188
 - j in component INa (dimensionless): 0.880161
 - hsp in component INa (dimensionless): 0.726193
 - jp in component INa (dimensionless): 0.880142
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.709237
 - hLp in component INaL (dimensionless): 0.449445
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.616183
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.689312
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.927247
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999858
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001594
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.354575
 - xs1 in component IKs (dimensionless): 0.253744
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997334
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:46:18 (3664): called boinc_finish(0)

</stderr_txt>
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