𝕏

Task 55258057

Name HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_724_2
Workunit 26041173
Created 29 Jun 2024, 6:46:52 UTC
Sent 29 Jun 2024, 10:11:25 UTC
Report deadline 2 Jul 2024, 19:47:25 UTC
Received 2 Jul 2024, 20:22:26 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236758
Run time 2 hours 36 min 39 sec
CPU time 2 hours 33 min 26 sec
Validate state Valid
Credit 66.24
Device peak FLOPS 3.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 6.99 MB
Peak swap size 1.55 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_724.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_724_2_r48436346_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626145050251776_ORdGradInc_k_24-Pueyo_APDR-conf_724_2_r48436346_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 118.277017
     * GNaL_b in INaL: 0.005763
     * Gto_b in Ito: 0.079200
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.034038
     * GKs_b in IKs: 0.001865
     * GK1_b in IK1: 0.147194
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 63.839109
     * GKb_b in IKb: 0.003963
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036308
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14402147, states[0] = -94.983918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28962912, states[0] = -94.977889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43631668, states[0] = -61.134468, states[40]= 0.000004
Saving checkpoint... 
Iteration: 58178236, states[0] = -94.702911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72790276, states[0] = -94.882960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87406162, states[0] = -94.941614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102021045, states[0] = 20.731967, states[40]= 0.009513
Saving checkpoint... 
Iteration: 116153206, states[0] = -89.686306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130095349, states[0] = -21.269342, states[40]= 0.000882
Saving checkpoint... 
Iteration: 144604293, states[0] = -30.302597, states[40]= 0.000429
Saving checkpoint... 
Iteration: 159121511, states[0] = -48.436165, states[40]= 0.000034
Saving checkpoint... 
Iteration: 173593716, states[0] = -19.561475, states[40]= 0.001004
Saving checkpoint... 
Iteration: 188063583, states[0] = 3.909377, states[40]= 0.004787
Saving checkpoint... 
Iteration: 202589561, states[0] = -15.362851, states[40]= 0.001457
Saving checkpoint... 
Iteration: 216883747, states[0] = -94.929357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230413265, states[0] = -94.938501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244977160, states[0] = -94.951425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259440152, states[0] = -94.944851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273950979, states[0] = -94.946988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288449339, states[0] = -94.946658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302890387, states[0] = -94.931484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316931923, states[0] = -94.942991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330608531, states[0] = -34.567537, states[40]= 0.000261
Saving checkpoint... 
Iteration: 345137527, states[0] = -66.983500, states[40]= 0.000001
Saving checkpoint... 
Iteration: 359723730, states[0] = -94.790367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374254888, states[0] = -94.837115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388832958, states[0] = -94.905799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403300005, states[0] = -94.883171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417818488, states[0] = -94.896749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432291274, states[0] = -94.875807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446798470, states[0] = -94.881899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461129695, states[0] = -57.639507, states[40]= 0.000007
Saving checkpoint... 
Iteration: 475664104, states[0] = -94.360907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490159106, states[0] = -93.453103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504605405, states[0] = -31.378936, states[40]= 0.000382
Saving checkpoint... 
Iteration: 518545070, states[0] = 12.280148, states[40]= 0.005290
Saving checkpoint... 
Iteration: 533035219, states[0] = 16.181914, states[40]= 0.005848
Saving checkpoint... 
Iteration: 547586827, states[0] = -12.659789, states[40]= 0.001888
Saving checkpoint... 
Iteration: 562078299, states[0] = -5.158224, states[40]= 0.003461
Saving checkpoint... 
Iteration: 576604086, states[0] = -30.039112, states[40]= 0.000440
Saving checkpoint... 
Iteration: 591170539, states[0] = -94.628437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605700923, states[0] = -94.746043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620060875, states[0] = 5.260667, states[40]= 0.004883
Saving checkpoint... 
Iteration: 634581253, states[0] = -7.554978, states[40]= 0.002940
Saving checkpoint... 
Iteration: 649091573, states[0] = -17.372996, states[40]= 0.001209
Saving checkpoint... 
Iteration: 663142501, states[0] = -73.707455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677693348, states[0] = -94.729468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692206578, states[0] = -94.757747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706689792, states[0] = -94.721351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720558870, states[0] = 6.220371, states[40]= 0.004941
Saving checkpoint... 
Iteration: 734838391, states[0] = -94.908666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749380681, states[0] = -94.927799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763928141, states[0] = -94.941844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778447398, states[0] = -94.945972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793006453, states[0] = 26.734589, states[40]= 0.117096
Saving checkpoint... 
Iteration: 807554738, states[0] = 8.120979, states[40]= 0.005041
Saving checkpoint... 
Iteration: 822114619, states[0] = -40.895264, states[40]= 0.000108
Saving checkpoint... 
Iteration: 836680976, states[0] = -94.698776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851254495, states[0] = -94.836325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865564628, states[0] = 3.378965, states[40]= 0.004743
Saving checkpoint... 
Iteration: 879939565, states[0] = -94.944319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894441026, states[0] = -94.944616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909017796, states[0] = 21.575082, states[40]= 0.013054
Saving checkpoint... 
Iteration: 922662440, states[0] = -94.177959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936713368, states[0] = -94.771027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951234290, states[0] = -94.807522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965768534, states[0] = -94.852997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980270872, states[0] = -94.855549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994762409, states[0] = -94.845972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009231282, states[0] = -94.802683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023488551, states[0] = -94.952492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037989014, states[0] = -94.952544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052447963, states[0] = -94.945919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066842509, states[0] = -94.910692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081367569, states[0] = -94.922471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095860346, states[0] = -94.919350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110451174, states[0] = -94.946500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124053493, states[0] = 8.676773, states[40]= 0.005069
Saving checkpoint... 
Iteration: 1138021250, states[0] = 20.706011, states[40]= 0.009378
Saving checkpoint... 
Iteration: 1152598527, states[0] = -24.408313, states[40]= 0.000707
Saving checkpoint... 
Iteration: 1167126023, states[0] = -53.460142, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1181660926, states[0] = -93.924187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196023013, states[0] = 20.224144, states[40]= 0.008371
Saving checkpoint... 
Iteration: 1210510970, states[0] = 23.342825, states[40]= 0.043710
Saving checkpoint... 
Iteration: 1224992261, states[0] = -94.952853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239528867, states[0] = 18.428216, states[40]= 0.006653
Saving checkpoint... 
Iteration: 1254007096, states[0] = 25.867777, states[40]= 0.103450
Saving checkpoint... 
Iteration: 1268471274, states[0] = -94.949863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282993634, states[0] = -94.952992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297442761, states[0] = -94.944734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312063304, states[0] = 4.057248, states[40]= 0.004798
Saving checkpoint... 
Iteration: 1326109676, states[0] = -35.741622, states[40]= 0.000224
Saving checkpoint... 
Iteration: 1340644862, states[0] = -77.246904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355227789, states[0] = -94.796713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369759695, states[0] = -94.842498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384270697, states[0] = -94.855117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398764069, states[0] = -94.847673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413317834, states[0] = -94.895714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427864259, states[0] = -94.920864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442483651, states[0] = -94.951579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457131752, states[0] = -60.013161, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1471728063, states[0] = -94.797102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486367733, states[0] = -94.922297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501025546, states[0] = -72.655418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1515596333, states[0] = -95.218953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1529602578, states[0] = -95.124054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543956046, states[0] = -95.016018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1558429798, states[0] = -95.189933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572849753, states[0] = -95.220632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1587277414, states[0] = -95.251143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601679744, states[0] = -95.255245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616076157, states[0] = -95.253623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630523493, states[0] = 19.248220, states[40]= 0.009349
Saving checkpoint... 
Iteration: 1644901597, states[0] = 49.928930, states[40]= 0.048050
Saving checkpoint... 
Iteration: 1659298576, states[0] = -95.272368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673601189, states[0] = -95.156794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1687986377, states[0] = -95.125797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1702333453, states[0] = -91.498775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1716746250, states[0] = -94.923293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1729798230, states[0] = -95.272626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1744240876, states[0] = 11.016930, states[40]= 0.006218
Saving checkpoint... 
Iteration: 1758684922, states[0] = -27.148218, states[40]= 0.000581
Saving checkpoint... 
Iteration: 1773130480, states[0] = -88.174325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1787524663, states[0] = -78.684773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1801995310, states[0] = -95.029963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1816446422, states[0] = -94.997236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1830760875, states[0] = -94.879199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845243484, states[0] = -94.844584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1859561159, states[0] = 4.820295, states[40]= 0.004865
Saving checkpoint... 
Iteration: 1873954616, states[0] = -94.956935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1888335286, states[0] = -94.913044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902795264, states[0] = -94.882876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1917221681, states[0] = -94.788844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1930895988, states[0] = -94.934315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945429568, states[0] = -94.942769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1959948596, states[0] = -94.946342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1974485617, states[0] = -94.952072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988970321, states[0] = -94.949624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003428585, states[0] = -94.941417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017744703, states[0] = -94.822558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2032137843, states[0] = -67.392024, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2046635529, states[0] = -64.504846, states[40]= 0.000002
Saving checkpoint... 
Iteration: 2061057115, states[0] = 7.038536, states[40]= 0.004986
Saving checkpoint... 
Iteration: 2075438077, states[0] = -94.943271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2089844115, states[0] = -94.910894, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.829119
 - CaMKt in component CaMK (millimolar): 0.006795
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.771811
 - nass in component intracellular_ions (millimolar): 6.771871
 - ki in component intracellular_ions (millimolar): 145.206676
 - kss in component intracellular_ions (millimolar): 145.206655
 - cansr in component intracellular_ions (millimolar): 1.309740
 - cajsr in component intracellular_ions (millimolar): 1.272776
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003645
 - hf in component INa (dimensionless): 0.878733
 - hs in component INa (dimensionless): 0.878728
 - j in component INa (dimensionless): 0.878698
 - hsp in component INa (dimensionless): 0.723445
 - jp in component INa (dimensionless): 0.878678
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709705
 - hLp in component INaL (dimensionless): 0.455011
 - a in component Ito (dimensionless): 0.000627
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.629064
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.705290
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940133
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999903
 - jca in component ICaL (dimensionless): 0.999982
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001600
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331466
 - xs1 in component IKs (dimensionless): 0.228355
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997356
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:22:12 (1960): called boinc_finish(0)

</stderr_txt>
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