𝕏

Task 55256610

Name HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_MID_10000-conf_762_2
Workunit 25992900
Created 29 Jun 2024, 1:27:40 UTC
Sent 29 Jun 2024, 10:02:21 UTC
Report deadline 2 Jul 2024, 10:02:21 UTC
Received 30 Jun 2024, 1:01:22 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238472
Run time 3 hours 43 min 28 sec
CPU time 2 hours 45 min 32 sec
Validate state Valid
Credit 44.81
Device peak FLOPS 2.31 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 3.58 MB
Peak swap size 1.22 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_MID_10000-conf_762.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_MID_10000-conf_762_2_r973261321_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_MID_10000-conf_762_2_r973261321_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 115.216065
     * GNaL_b in INaL: 0.006055
     * Gto_b in Ito: 0.090709
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033686
     * GKs_b in IKs: 0.001786
     * GK1_b in IK1: 0.165017
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 66.892728
     * GKb_b in IKb: 0.003863
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.047939
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 6035984, states[0] = -94.186328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14778991, states[0] = -94.139309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21996789, states[0] = -94.135916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30725176, states[0] = -94.155496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39217805, states[0] = -94.135537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47828668, states[0] = -94.142530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56572046, states[0] = -94.160551, states[40]= 0.000001
Saving checkpoint... 
Iteration: 65252425, states[0] = -49.297118, states[40]= 0.000430
Saving checkpoint... 
Iteration: 73303495, states[0] = -94.157747, states[40]= 0.000001
Saving checkpoint... 
Iteration: 79684049, states[0] = -94.161704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85224758, states[0] = -33.062842, states[40]= 0.002999
Saving checkpoint... 
Iteration: 92744838, states[0] = -94.167279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 100022009, states[0] = 32.954553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108794876, states[0] = -94.170913, states[40]= 0.000001
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Iteration: 115812286, states[0] = -94.200815, states[40]= 0.000001
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Iteration: 124531249, states[0] = -94.174917, states[40]= 0.000001
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Iteration: 133256045, states[0] = -94.175573, states[40]= 0.000001
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Iteration: 141780649, states[0] = -94.185264, states[40]= 0.000001
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Iteration: 150525908, states[0] = -94.153546, states[40]= 0.000000
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Iteration: 159322610, states[0] = -94.178671, states[40]= 0.000001
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Iteration: 167869307, states[0] = -94.179423, states[40]= 0.000001
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Iteration: 174464331, states[0] = -94.179771, states[40]= 0.000001
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Iteration: 182231299, states[0] = -94.183195, states[40]= 0.000001
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Iteration: 190943607, states[0] = -94.207190, states[40]= 0.000001
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Iteration: 198003308, states[0] = -94.180337, states[40]= 0.000001
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Iteration: 206686022, states[0] = -94.190230, states[40]= 0.000001
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Iteration: 215387090, states[0] = -93.999488, states[40]= 0.000000
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Iteration: 222627012, states[0] = -94.181886, states[40]= 0.000001
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Iteration: 231099981, states[0] = -94.204101, states[40]= 0.000001
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Iteration: 239015077, states[0] = -94.180745, states[40]= 0.000001
Saving checkpoint... 
Iteration: 244089377, states[0] = -94.180850, states[40]= 0.000001
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Iteration: 252662604, states[0] = -94.181984, states[40]= 0.000001
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Iteration: 261341705, states[0] = -94.197781, states[40]= 0.000001
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Iteration: 268757478, states[0] = -94.180692, states[40]= 0.000001
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Iteration: 277304191, states[0] = -94.183925, states[40]= 0.000001
Saving checkpoint... 
Iteration: 286033800, states[0] = -94.206076, states[40]= 0.000001
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Iteration: 293554400, states[0] = -94.180650, states[40]= 0.000001
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Iteration: 301786475, states[0] = -94.189227, states[40]= 0.000001
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Iteration: 309924862, states[0] = -94.182087, states[40]= 0.000001
Saving checkpoint... 
Iteration: 317618273, states[0] = -94.182188, states[40]= 0.000001
Saving checkpoint... 
Iteration: 326269034, states[0] = -94.199610, states[40]= 0.000001
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Iteration: 333413145, states[0] = -94.180606, states[40]= 0.000001
Saving checkpoint... 
Iteration: 341240313, states[0] = -94.200338, states[40]= 0.000001
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Iteration: 349279980, states[0] = -94.181064, states[40]= 0.000001
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Iteration: 356390097, states[0] = -94.196516, states[40]= 0.000001
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Iteration: 364470219, states[0] = -94.181268, states[40]= 0.000001
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Iteration: 371370349, states[0] = -94.196941, states[40]= 0.000001
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Iteration: 379781935, states[0] = -94.181684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 388420854, states[0] = -94.180449, states[40]= 0.000001
Saving checkpoint... 
Iteration: 395612165, states[0] = -94.188859, states[40]= 0.000000
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Iteration: 404278506, states[0] = -94.180897, states[40]= 0.000001
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Iteration: 412758738, states[0] = -94.181410, states[40]= 0.000001
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Iteration: 421467715, states[0] = -94.194570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 430182847, states[0] = -19.183297, states[40]= 0.001129
Saving checkpoint... 
Iteration: 438905868, states[0] = -94.180413, states[40]= 0.000001
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Iteration: 444774085, states[0] = -94.181463, states[40]= 0.000001
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Iteration: 453419547, states[0] = -94.180238, states[40]= 0.000001
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Iteration: 462138702, states[0] = -94.184760, states[40]= 0.000001
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Iteration: 479322646, states[0] = -94.180703, states[40]= 0.000001
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Iteration: 487755824, states[0] = -94.181170, states[40]= 0.000001
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Iteration: 496427468, states[0] = -94.195206, states[40]= 0.000001
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Iteration: 505034547, states[0] = 33.811291, states[40]= 0.000000
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Iteration: 513222355, states[0] = -94.180160, states[40]= 0.000001
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Iteration: 520950045, states[0] = -94.207332, states[40]= 0.000001
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Iteration: 529546830, states[0] = -94.180836, states[40]= 0.000001
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Iteration: 538064972, states[0] = -94.180275, states[40]= 0.000001
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Iteration: 545302542, states[0] = -93.723383, states[40]= 0.000000
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Iteration: 553433339, states[0] = -94.179896, states[40]= 0.000001
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Iteration: 562010131, states[0] = -94.185667, states[40]= 0.000001
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Iteration: 567805867, states[0] = -94.180747, states[40]= 0.000001
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Iteration: 575396280, states[0] = -94.017528, states[40]= 0.000000
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Iteration: 583451826, states[0] = -94.179790, states[40]= 0.000001
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Iteration: 592134939, states[0] = -94.184354, states[40]= 0.000001
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Iteration: 600866431, states[0] = -94.208074, states[40]= 0.000001
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Iteration: 609546199, states[0] = -94.180564, states[40]= 0.000001
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Iteration: 616626117, states[0] = -94.190814, states[40]= 0.000001
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Iteration: 625393211, states[0] = -94.011467, states[40]= 0.000000
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Iteration: 634016504, states[0] = -94.179846, states[40]= 0.000001
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Iteration: 642511724, states[0] = -94.181633, states[40]= 0.000001
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Iteration: 649707486, states[0] = -94.180667, states[40]= 0.000001
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Iteration: 657352655, states[0] = -94.182483, states[40]= 0.000001
Saving checkpoint... 
Iteration: 665605289, states[0] = -94.186246, states[40]= 0.000000
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Iteration: 673032477, states[0] = -94.179871, states[40]= 0.000001
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Iteration: 681785571, states[0] = -94.188044, states[40]= 0.000001
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Iteration: 690550238, states[0] = -94.167597, states[40]= 0.000000
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Iteration: 699092174, states[0] = -94.179697, states[40]= 0.000001
Saving checkpoint... 
Iteration: 707730072, states[0] = -94.180510, states[40]= 0.000001
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Iteration: 716433259, states[0] = -94.194332, states[40]= 0.000001
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Iteration: 723610429, states[0] = -94.179311, states[40]= 0.000001
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Iteration: 732365865, states[0] = -94.182145, states[40]= 0.000001
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Iteration: 741084490, states[0] = -94.203317, states[40]= 0.000001
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Iteration: 749624766, states[0] = -94.180204, states[40]= 0.000001
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Iteration: 755365539, states[0] = -93.948692, states[40]= 0.000000
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Iteration: 762558025, states[0] = -94.181005, states[40]= 0.000001
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Iteration: 771156904, states[0] = -94.201206, states[40]= 0.000001
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Iteration: 779831576, states[0] = -94.180420, states[40]= 0.000001
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Iteration: 786260709, states[0] = -94.198323, states[40]= 0.000001
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Iteration: 794228628, states[0] = -94.179523, states[40]= 0.000001
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Iteration: 801013356, states[0] = -94.204982, states[40]= 0.000001
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Iteration: 808402459, states[0] = -94.179042, states[40]= 0.000001
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Iteration: 817137456, states[0] = -94.183570, states[40]= 0.000001
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Iteration: 824247254, states[0] = -94.179443, states[40]= 0.000001
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Iteration: 832900756, states[0] = -94.179599, states[40]= 0.000001
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Iteration: 841581170, states[0] = -94.190872, states[40]= 0.000001
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Iteration: 847973721, states[0] = -94.179388, states[40]= 0.000001
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Iteration: 852071719, states[0] = -94.184060, states[40]= 0.000001
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Iteration: 855902073, states[0] = -94.206944, states[40]= 0.000001
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Iteration: 856164195, states[0] = -94.200715, states[40]= 0.000001
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Iteration: 864548473, states[0] = -94.179703, states[40]= 0.000001
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Iteration: 870329040, states[0] = -93.833911, states[40]= 0.000000
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Iteration: 877481874, states[0] = -94.180989, states[40]= 0.000001
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Iteration: 883847864, states[0] = -94.178868, states[40]= 0.000001
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Iteration: 892033137, states[0] = -94.184309, states[40]= 0.000001
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Iteration: 897365254, states[0] = -94.181590, states[40]= 0.000001
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Iteration: 902228671, states[0] = -94.182527, states[40]= 0.000001
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Iteration: 908967085, states[0] = -94.178871, states[40]= 0.000001
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Iteration: 914495845, states[0] = -94.179459, states[40]= 0.000001
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Iteration: 919418460, states[0] = -94.179337, states[40]= 0.000001
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Iteration: 926164920, states[0] = -94.200459, states[40]= 0.000001
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Iteration: 934066198, states[0] = -94.178875, states[40]= 0.000001
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Iteration: 946978685, states[0] = -94.184703, states[40]= 0.000001
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Iteration: 962688632, states[0] = -94.179791, states[40]= 0.000001
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Iteration: 982663514, states[0] = -94.179817, states[40]= 0.000001
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Iteration: 993043668, states[0] = -94.178768, states[40]= 0.000001
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Iteration: 1004886325, states[0] = -94.179745, states[40]= 0.000001
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Iteration: 1012652708, states[0] = -94.179757, states[40]= 0.000001
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Iteration: 1030096731, states[0] = 17.561535, states[40]= 0.000003
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Iteration: 1036195058, states[0] = -94.199252, states[40]= 0.000001
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Iteration: 1054642496, states[0] = -94.179196, states[40]= 0.000001
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Iteration: 1060470558, states[0] = -94.115203, states[40]= 0.000000
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Iteration: 1066246037, states[0] = -94.197766, states[40]= 0.000001
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Iteration: 1072598982, states[0] = -94.179773, states[40]= 0.000001
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Iteration: 1120220637, states[0] = -34.648670, states[40]= 0.002262
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Iteration: 1125292686, states[0] = -93.665872, states[40]= 0.000000
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Iteration: 1131097134, states[0] = -94.201650, states[40]= 0.000001
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Iteration: 1139565458, states[0] = -94.178795, states[40]= 0.000001
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Iteration: 1146695624, states[0] = -94.187843, states[40]= 0.000001
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Iteration: 1160512182, states[0] = -94.146263, states[40]= 0.000000
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Iteration: 1185968762, states[0] = -94.204708, states[40]= 0.000001
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Iteration: 1193045242, states[0] = -94.178087, states[40]= 0.000001
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Iteration: 1219841695, states[0] = -94.178944, states[40]= 0.000001
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Iteration: 1238527669, states[0] = -94.177560, states[40]= 0.000001
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Iteration: 1253731678, states[0] = -94.177551, states[40]= 0.000001
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Iteration: 1260202856, states[0] = -25.755619, states[40]= 0.003558
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Iteration: 1265399349, states[0] = -94.020871, states[40]= 0.000000
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Iteration: 1270651885, states[0] = -94.193808, states[40]= 0.000000
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Iteration: 1305357600, states[0] = -93.925388, states[40]= 0.000000
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Iteration: 1317948415, states[0] = -94.177848, states[40]= 0.000001
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Iteration: 1322822834, states[0] = -94.178140, states[40]= 0.000001
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Iteration: 1327975403, states[0] = -94.177758, states[40]= 0.000001
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Iteration: 1333191071, states[0] = -94.177413, states[40]= 0.000001
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Iteration: 1337968585, states[0] = -94.177738, states[40]= 0.000001
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Iteration: 1345189787, states[0] = -21.566083, states[40]= 0.002161
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Iteration: 1352291180, states[0] = -94.180541, states[40]= 0.000001
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Iteration: 1359562310, states[0] = -94.178045, states[40]= 0.000001
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Iteration: 1368082463, states[0] = -94.177435, states[40]= 0.000001
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Iteration: 1375103177, states[0] = 15.227741, states[40]= 0.000006
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Iteration: 1381818994, states[0] = -94.185204, states[40]= 0.000001
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Iteration: 1387859974, states[0] = -94.177819, states[40]= 0.000001
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Iteration: 1393722360, states[0] = -94.177073, states[40]= 0.000001
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Iteration: 1400917113, states[0] = -94.204908, states[40]= 0.000001
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Iteration: 1407348464, states[0] = -94.179969, states[40]= 0.000001
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Iteration: 1411082804, states[0] = -94.201097, states[40]= 0.000001
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Iteration: 1416283252, states[0] = -94.195599, states[40]= 0.000001
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Iteration: 1421743754, states[0] = -94.186156, states[40]= 0.000001
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Iteration: 1428149650, states[0] = -94.177139, states[40]= 0.000001
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Iteration: 1433638083, states[0] = -94.176910, states[40]= 0.000001
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Iteration: 1448507564, states[0] = -94.176849, states[40]= 0.000001
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Iteration: 1455259212, states[0] = -66.071903, states[40]= 0.000028
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Iteration: 1462226230, states[0] = -94.180649, states[40]= 0.000001
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Iteration: 1466966739, states[0] = -94.183075, states[40]= 0.000001
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Iteration: 1473407452, states[0] = -94.176786, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1478791310, states[0] = -94.176817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1482836154, states[0] = -94.177561, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1489021223, states[0] = -94.176952, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1494898264, states[0] = -94.178103, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.054240
 - CaMKt in component CaMK (millimolar): 0.000839
 - cass in component intracellular_ions (millimolar): 0.000092
 - nai in component intracellular_ions (millimolar): 7.763347
 - nass in component intracellular_ions (millimolar): 7.763486
 - ki in component intracellular_ions (millimolar): 144.115711
 - kss in component intracellular_ions (millimolar): 144.115699
 - cansr in component intracellular_ions (millimolar): 1.691048
 - cajsr in component intracellular_ions (millimolar): 1.691837
 - cai in component intracellular_ions (millimolar): 0.000097
 - m in component INa (dimensionless): 0.003942
 - hf in component INa (dimensionless): 0.864496
 - hs in component INa (dimensionless): 0.864496
 - j in component INa (dimensionless): 0.864496
 - hsp in component INa (dimensionless): 0.697287
 - jp in component INa (dimensionless): 0.864495
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706231
 - hLp in component INaL (dimensionless): 0.512277
 - a in component Ito (dimensionless): 0.000660
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.999845
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.999848
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999987
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003762
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000006
 - xs1 in component IKs (dimensionless): 0.002825
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997551
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
19:00:51 (2432): called boinc_finish(0)

</stderr_txt>
]]>