𝕏

Task 55255801

Name HuVeMOp_20240625112745323441_ORdGradInc_k_24-BASE_EPI-conf_634_2
Workunit 25983040
Created 28 Jun 2024, 22:52:40 UTC
Sent 29 Jun 2024, 9:52:08 UTC
Report deadline 2 Jul 2024, 9:52:08 UTC
Received 1 Jul 2024, 7:19:55 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236767
Run time 1 hours 36 min 46 sec
CPU time 1 hours 35 min 39 sec
Validate state Valid
Credit 43.33
Device peak FLOPS 3.23 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.96 MB
Peak swap size 6.24 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-BASE_EPI-conf_634.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-BASE_EPI-conf_634_2_r793259596_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-BASE_EPI-conf_634_2_r793259596_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 104.469769
     * GNaL_b in INaL: 0.005991
     * Gto_b in Ito: 0.069313
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033545
     * GKs_b in IKs: 0.001809
     * GK1_b in IK1: 0.167840
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 66.382601
     * GKb_b in IKb: 0.003930
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.052223
     * celltype in environment: 1.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 5751154, states[0] = -86.957036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14297966, states[0] = -86.985949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22888546, states[0] = -87.069246, states[40]= 0.000001
Saving checkpoint... 
Iteration: 31359224, states[0] = -87.064889, states[40]= 0.000001
Saving checkpoint... 
Iteration: 39980845, states[0] = -87.119938, states[40]= 0.000001
Saving checkpoint... 
Iteration: 48453462, states[0] = -87.125168, states[40]= 0.000001
Saving checkpoint... 
Iteration: 57082657, states[0] = 1.484952, states[40]= 0.000011
Saving checkpoint... 
Iteration: 63266401, states[0] = -86.975205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71967302, states[0] = -87.145426, states[40]= 0.000001
Saving checkpoint... 
Iteration: 80416585, states[0] = -87.136595, states[40]= 0.000001
Saving checkpoint... 
Iteration: 88892236, states[0] = -87.129759, states[40]= 0.000001
Saving checkpoint... 
Iteration: 97461405, states[0] = -87.152934, states[40]= 0.000001
Saving checkpoint... 
Iteration: 106086406, states[0] = -1.934142, states[40]= 0.000014
Saving checkpoint... 
Iteration: 114521102, states[0] = 20.214354, states[40]= 0.000881
Saving checkpoint... 
Iteration: 123082972, states[0] = 0.648075, states[40]= 0.000011
Saving checkpoint... 
Iteration: 131752274, states[0] = -86.956572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140337567, states[0] = -87.100122, states[40]= 0.000001
Saving checkpoint... 
Iteration: 148925951, states[0] = -87.148892, states[40]= 0.000001
Saving checkpoint... 
Iteration: 157574036, states[0] = 6.288858, states[40]= 0.000004
Saving checkpoint... 
Iteration: 165749667, states[0] = -86.949728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178044580, states[0] = 18.130701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189588303, states[0] = -3.721961, states[40]= 0.000016
Saving checkpoint... 
Iteration: 198624954, states[0] = -47.532806, states[40]= 0.000004
Saving checkpoint... 
Iteration: 207427441, states[0] = -87.148927, states[40]= 0.000001
Saving checkpoint... 
Iteration: 216307731, states[0] = -87.066630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225144130, states[0] = -75.808892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233962181, states[0] = -87.156558, states[40]= 0.000001
Saving checkpoint... 
Iteration: 242717430, states[0] = -86.828743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251420347, states[0] = -87.145749, states[40]= 0.000001
Saving checkpoint... 
Iteration: 260049195, states[0] = 16.885491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268548701, states[0] = 17.030510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277205131, states[0] = -86.766057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285120101, states[0] = -41.295046, states[40]= 0.000008
Saving checkpoint... 
Iteration: 293744063, states[0] = -86.929993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302361282, states[0] = -87.116282, states[40]= 0.000001
Saving checkpoint... 
Iteration: 310969627, states[0] = -87.155951, states[40]= 0.000001
Saving checkpoint... 
Iteration: 319699796, states[0] = -86.734739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328386119, states[0] = -87.130022, states[40]= 0.000001
Saving checkpoint... 
Iteration: 337001863, states[0] = 26.048517, states[40]= 1.391267
Saving checkpoint... 
Iteration: 345583990, states[0] = -0.183846, states[40]= 0.000012
Saving checkpoint... 
Iteration: 354129473, states[0] = -53.503825, states[40]= 0.000002
Saving checkpoint... 
Iteration: 362721825, states[0] = -86.845297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371168919, states[0] = -86.507607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378372641, states[0] = -87.121466, states[40]= 0.000001
Saving checkpoint... 
Iteration: 386064489, states[0] = 11.098566, states[40]= 0.000001
Saving checkpoint... 
Iteration: 394288330, states[0] = -87.032545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402548218, states[0] = 17.170484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411099486, states[0] = -15.903899, states[40]= 0.000015
Saving checkpoint... 
Iteration: 416829030, states[0] = -87.086452, states[40]= 0.000001
Saving checkpoint... 
Iteration: 425065961, states[0] = 10.422383, states[40]= 0.000002
Saving checkpoint... 
Iteration: 433399256, states[0] = -87.133302, states[40]= 0.000001
Saving checkpoint... 
Iteration: 441807135, states[0] = -87.060104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450126234, states[0] = -49.211367, states[40]= 0.000004
Saving checkpoint... 
Iteration: 458421582, states[0] = -87.140829, states[40]= 0.000001
Saving checkpoint... 
Iteration: 466528220, states[0] = 20.351274, states[40]= 0.000058
Saving checkpoint... 
Iteration: 474902455, states[0] = -87.133544, states[40]= 0.000001
Saving checkpoint... 
Iteration: 483211151, states[0] = -86.792191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491524917, states[0] = 20.367774, states[40]= 0.000203
Saving checkpoint... 
Iteration: 499907288, states[0] = -87.134789, states[40]= 0.000001
Saving checkpoint... 
Iteration: 508193106, states[0] = -86.688711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516615412, states[0] = -35.402940, states[40]= 0.000012
Saving checkpoint... 
Iteration: 525026113, states[0] = 20.379297, states[40]= 0.000129
Saving checkpoint... 
Iteration: 530714452, states[0] = -86.807173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539220446, states[0] = -86.834602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547489131, states[0] = -87.152688, states[40]= 0.000001
Saving checkpoint... 
Iteration: 555740506, states[0] = -86.911542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564161038, states[0] = -86.358069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570481283, states[0] = -87.151043, states[40]= 0.000001
Saving checkpoint... 
Iteration: 579106951, states[0] = -25.016870, states[40]= 0.000015
Saving checkpoint... 
Iteration: 587680070, states[0] = -86.595921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596077708, states[0] = 4.104590, states[40]= 0.000006
Saving checkpoint... 
Iteration: 604435334, states[0] = -87.141047, states[40]= 0.000001
Saving checkpoint... 
Iteration: 612853035, states[0] = -87.102373, states[40]= 0.000001
Saving checkpoint... 
Iteration: 621341867, states[0] = -87.093170, states[40]= 0.000001
Saving checkpoint... 
Iteration: 629579681, states[0] = 2.847568, states[40]= 0.000008
Saving checkpoint... 
Iteration: 638041975, states[0] = 18.715294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646385103, states[0] = -87.121282, states[40]= 0.000001
Saving checkpoint... 
Iteration: 654765289, states[0] = -86.978949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662891061, states[0] = -87.123733, states[40]= 0.000001
Saving checkpoint... 
Iteration: 671201430, states[0] = -86.734901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679581340, states[0] = 1.733096, states[40]= 0.000009
Saving checkpoint... 
Iteration: 687971251, states[0] = -87.146475, states[40]= 0.000001
Saving checkpoint... 
Iteration: 696286120, states[0] = -87.020793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704532782, states[0] = 20.087858, states[40]= 0.000011
Saving checkpoint... 
Iteration: 707803320, states[0] = -87.047905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713594409, states[0] = -9.907120, states[40]= 0.000018
Saving checkpoint... 
Iteration: 722061760, states[0] = 12.298807, states[40]= 0.000001
Saving checkpoint... 
Iteration: 730467290, states[0] = -87.144709, states[40]= 0.000001
Saving checkpoint... 
Iteration: 738893860, states[0] = -87.123045, states[40]= 0.000001
Saving checkpoint... 
Iteration: 744825336, states[0] = -87.074091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 753752413, states[0] = -86.942995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762238958, states[0] = -86.900892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770885110, states[0] = -87.118060, states[40]= 0.000001
Saving checkpoint... 
Iteration: 779633640, states[0] = -59.190910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 788024792, states[0] = 20.367462, states[40]= 0.000212
Saving checkpoint... 
Iteration: 796723551, states[0] = -86.841259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803965671, states[0] = -87.142524, states[40]= 0.000001
Saving checkpoint... 
Iteration: 812527685, states[0] = 20.366467, states[40]= 0.000071
Saving checkpoint... 
Iteration: 819469800, states[0] = -87.142833, states[40]= 0.000001
Saving checkpoint... 
Iteration: 827987107, states[0] = -87.145174, states[40]= 0.000001
Saving checkpoint... 
Iteration: 836343505, states[0] = -87.088989, states[40]= 0.000001
Saving checkpoint... 
Iteration: 844882057, states[0] = -87.114582, states[40]= 0.000001
Saving checkpoint... 
Iteration: 853321160, states[0] = -87.066700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861666589, states[0] = -86.467759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870192665, states[0] = -86.676245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878643131, states[0] = -74.081960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887030892, states[0] = 20.233033, states[40]= 0.000022
Saving checkpoint... 
Iteration: 895474860, states[0] = -87.141683, states[40]= 0.000001
Saving checkpoint... 
Iteration: 903969741, states[0] = -87.140638, states[40]= 0.000001
Saving checkpoint... 
Iteration: 912482544, states[0] = -87.142375, states[40]= 0.000001
Saving checkpoint... 
Iteration: 920984434, states[0] = -87.142414, states[40]= 0.000001
Saving checkpoint... 
Iteration: 929546849, states[0] = 17.554168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938160409, states[0] = -86.322282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944645461, states[0] = -77.921862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953120368, states[0] = -41.614543, states[40]= 0.000008
Saving checkpoint... 
Iteration: 961621203, states[0] = -42.678856, states[40]= 0.000007
Saving checkpoint... 
Iteration: 970126380, states[0] = -49.385168, states[40]= 0.000004
Saving checkpoint... 
Iteration: 976568868, states[0] = 9.023935, states[40]= 0.000002
Saving checkpoint... 
Iteration: 984932258, states[0] = -87.130366, states[40]= 0.000001
Saving checkpoint... 
Iteration: 993418805, states[0] = -87.126084, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1001876842, states[0] = -87.107706, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1010481582, states[0] = -87.139705, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1019016593, states[0] = 19.690579, states[40]= 0.005153
Saving checkpoint... 
Iteration: 1027560457, states[0] = 12.848546, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1036117964, states[0] = -38.573837, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1044449972, states[0] = -87.133201, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1053286138, states[0] = -87.011519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061873338, states[0] = -87.104159, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1070528291, states[0] = 20.353654, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1079147426, states[0] = -80.740238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087703394, states[0] = -86.734989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096131926, states[0] = -56.796541, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1104539640, states[0] = 19.171604, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1112932374, states[0] = -87.127085, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1121282200, states[0] = -87.002530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129750912, states[0] = -86.928852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138243833, states[0] = -86.907119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146797955, states[0] = -87.028587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155278484, states[0] = -86.994472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163874887, states[0] = -87.102406, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1172166637, states[0] = -86.459933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179134979, states[0] = -61.082555, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1187738757, states[0] = -86.889030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196411405, states[0] = -87.118279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1205171474, states[0] = -86.509617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211520550, states[0] = 20.158699, states[40]= 0.001085
Saving checkpoint... 
Iteration: 1220346065, states[0] = -87.081153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1229030430, states[0] = 20.263436, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1237629665, states[0] = -53.728287, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1246230984, states[0] = -86.859350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254863777, states[0] = -87.093253, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1263433118, states[0] = -87.123394, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1271860055, states[0] = -87.090316, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1280437393, states[0] = -87.124092, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1288923106, states[0] = -87.119810, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1297494537, states[0] = -87.133944, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1306029615, states[0] = 20.306094, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1314590223, states[0] = -5.498793, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1320816019, states[0] = -87.048568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329536259, states[0] = 19.703924, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1338171410, states[0] = -86.505461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346762268, states[0] = -86.953551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355277225, states[0] = -86.986739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363733846, states[0] = -86.866981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372264899, states[0] = -86.959269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380798601, states[0] = -87.023475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389163872, states[0] = -86.410697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397689804, states[0] = -86.643417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406125410, states[0] = -48.100488, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1414686737, states[0] = -86.622062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423157122, states[0] = -86.072275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429173856, states[0] = -86.524247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437608721, states[0] = -27.150532, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1446170400, states[0] = -86.493214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454668503, states[0] = -86.473977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463508210, states[0] = 16.415279, states[40]= 0.154675
Saving checkpoint... 
Iteration: 1471975219, states[0] = -87.126825, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1480602774, states[0] = -19.889556, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1489392214, states[0] = -87.102855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1498369085, states[0] = -87.090304, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.005189
 - CaMKt in component CaMK (millimolar): 0.017889
 - cass in component intracellular_ions (millimolar): 0.000079
 - nai in component intracellular_ions (millimolar): 7.360682
 - nass in component intracellular_ions (millimolar): 7.360781
 - ki in component intracellular_ions (millimolar): 144.258252
 - kss in component intracellular_ions (millimolar): 144.258217
 - cansr in component intracellular_ions (millimolar): 2.130990
 - cajsr in component intracellular_ions (millimolar): 2.075891
 - cai in component intracellular_ions (millimolar): 0.000081
 - m in component INa (dimensionless): 0.008017
 - hf in component INa (dimensionless): 0.667061
 - hs in component INa (dimensionless): 0.667051
 - j in component INa (dimensionless): 0.666989
 - hsp in component INa (dimensionless): 0.419711
 - jp in component INa (dimensionless): 0.666941
 - mL in component INaL (dimensionless): 0.000222
 - hL in component INaL (dimensionless): 0.471620
 - hLp in component INaL (dimensionless): 0.245336
 - a in component Ito (dimensionless): 0.001062
 - iF in component Ito (dimensionless): 0.999481
 - iS in component Ito (dimensionless): 0.999444
 - ap in component Ito (dimensionless): 0.000541
 - iFp in component Ito (dimensionless): 0.999481
 - iSp in component Ito (dimensionless): 0.999472
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930928
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999899
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002112
 - xrf in component IKr (dimensionless): 0.000009
 - xrs in component IKr (dimensionless): 0.362591
 - xs1 in component IKs (dimensionless): 0.257776
 - xs2 in component IKs (dimensionless): 0.000213
 - xk1 in component IK1 (dimensionless): 0.996981
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
02:01:37 (10432): called boinc_finish(0)

</stderr_txt>
]]>


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