𝕏

Task 55252167

Name HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pueyo_APDR-conf_42_2
Workunit 25900454
Created 28 Jun 2024, 12:15:14 UTC
Sent 29 Jun 2024, 9:27:48 UTC
Report deadline 2 Jul 2024, 19:03:48 UTC
Received 1 Jul 2024, 20:33:17 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 226324
Run time 2 hours 43 min 14 sec
CPU time 2 hours 32 min 55 sec
Validate state Valid
Credit 62.23
Device peak FLOPS 4.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.40 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pueyo_APDR-conf_42.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pueyo_APDR-conf_42_2_r497691113_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pueyo_APDR-conf_42_2_r497691113_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 111.300945
     * GNaL_b in INaL: 0.006964
     * Gto_b in Ito: 0.068244
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032941
     * GKs_b in IKs: 0.001769
     * GK1_b in IK1: 0.147821
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 61.571235
     * GKb_b in IKb: 0.003785
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.040742
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15919867, states[0] = -94.866680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30718394, states[0] = -94.699142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45957437, states[0] = -94.857271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60455524, states[0] = -94.853696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77298892, states[0] = -94.786846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92511095, states[0] = 25.212084, states[40]= 0.041685
Saving checkpoint... 
Iteration: 107360305, states[0] = -94.821702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122491106, states[0] = -94.853932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137250764, states[0] = -94.733611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151875644, states[0] = -94.826789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166978153, states[0] = -94.851423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183126415, states[0] = -47.377907, states[40]= 0.000043
Saving checkpoint... 
Iteration: 198831040, states[0] = -94.805258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214569421, states[0] = 2.878162, states[40]= 0.004749
Saving checkpoint... 
Iteration: 228899056, states[0] = -94.834292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244158473, states[0] = -88.567177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259390745, states[0] = -94.831620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274990322, states[0] = -94.852700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290746053, states[0] = -94.726464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306902747, states[0] = -94.835301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322695623, states[0] = -94.638328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337866458, states[0] = -94.822577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352813575, states[0] = -94.793890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368263366, states[0] = -94.748351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383175800, states[0] = -94.536060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399468001, states[0] = -94.849472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414248415, states[0] = -94.729610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430287986, states[0] = -94.773534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445325554, states[0] = -94.801695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459985220, states[0] = -94.851923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474932853, states[0] = -94.842868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491546589, states[0] = 13.222842, states[40]= 0.005405
Saving checkpoint... 
Iteration: 506734832, states[0] = -94.709939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522410293, states[0] = -94.837307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537710452, states[0] = -94.667864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553400350, states[0] = -94.834447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569245075, states[0] = -94.724941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584182769, states[0] = -94.603333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599678543, states[0] = -94.574866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614647873, states[0] = -72.747702, states[40]= 0.000001
Saving checkpoint... 
Iteration: 630093149, states[0] = -14.458065, states[40]= 0.001590
Saving checkpoint... 
Iteration: 645706783, states[0] = -94.660733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661125704, states[0] = -46.595530, states[40]= 0.000049
Saving checkpoint... 
Iteration: 676761605, states[0] = -94.746118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691264279, states[0] = -94.749222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706908352, states[0] = -94.836670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721951961, states[0] = -94.846570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737921075, states[0] = -94.839980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753392962, states[0] = -94.832042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769872804, states[0] = -94.824885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784752813, states[0] = -94.735205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799316781, states[0] = -94.795834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814906182, states[0] = -94.836001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831268932, states[0] = -94.754360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847025600, states[0] = 21.033819, states[40]= 0.007713
Saving checkpoint... 
Iteration: 862553958, states[0] = 10.124732, states[40]= 0.005217
Saving checkpoint... 
Iteration: 877783141, states[0] = -94.768809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893133809, states[0] = -55.553518, states[40]= 0.000011
Saving checkpoint... 
Iteration: 909209399, states[0] = -94.665644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922880724, states[0] = -94.827773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935663980, states[0] = -92.932276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948698061, states[0] = -94.643062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961293941, states[0] = -94.778443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974580863, states[0] = -4.045671, states[40]= 0.003706
Saving checkpoint... 
Iteration: 988262302, states[0] = -94.746763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000902822, states[0] = -94.834930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014083640, states[0] = -6.115095, states[40]= 0.003265
Saving checkpoint... 
Iteration: 1027374735, states[0] = -94.825487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040077903, states[0] = -2.034018, states[40]= 0.004087
Saving checkpoint... 
Iteration: 1053556277, states[0] = 9.116445, states[40]= 0.005167
Saving checkpoint... 
Iteration: 1066030418, states[0] = 19.440137, states[40]= 0.006652
Saving checkpoint... 
Iteration: 1079129862, states[0] = -51.146812, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1092413007, states[0] = -94.837720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105240249, states[0] = -94.717744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118639446, states[0] = -62.011657, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1132678779, states[0] = -94.576876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146767418, states[0] = -94.752513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159766302, states[0] = -94.751258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172882327, states[0] = -94.828209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186121058, states[0] = -41.684183, states[40]= 0.000104
Saving checkpoint... 
Iteration: 1199111828, states[0] = -32.474539, states[40]= 0.000363
Saving checkpoint... 
Iteration: 1211875980, states[0] = -94.825858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224854839, states[0] = -94.816982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237838105, states[0] = -94.808546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250876524, states[0] = -94.826041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263688975, states[0] = -94.622838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276171654, states[0] = -94.389603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289069550, states[0] = 2.812611, states[40]= 0.004743
Saving checkpoint... 
Iteration: 1302097097, states[0] = -18.242236, states[40]= 0.001134
Saving checkpoint... 
Iteration: 1314597000, states[0] = -18.148672, states[40]= 0.001143
Saving checkpoint... 
Iteration: 1327842813, states[0] = -94.811008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341399070, states[0] = -94.833622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355152634, states[0] = -79.933092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369004736, states[0] = 32.537364, states[40]= 0.138896
Saving checkpoint... 
Iteration: 1382195513, states[0] = -94.637495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395587449, states[0] = -9.251691, states[40]= 0.002569
Saving checkpoint... 
Iteration: 1409131078, states[0] = -52.496711, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1422996126, states[0] = -94.852755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436692122, states[0] = -94.630113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450404898, states[0] = -94.835281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463669365, states[0] = -94.205375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477322482, states[0] = -94.799191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490862126, states[0] = -94.820096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504626078, states[0] = -66.961123, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1518494914, states[0] = -94.995678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1531963283, states[0] = -94.929512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1545745729, states[0] = -94.135935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1559466575, states[0] = -3.038210, states[40]= 0.004371
Saving checkpoint... 
Iteration: 1573705227, states[0] = -95.051440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1586852893, states[0] = -94.856436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600232735, states[0] = 16.646015, states[40]= 0.007273
Saving checkpoint... 
Iteration: 1613703969, states[0] = 36.311673, states[40]= 0.117403
Saving checkpoint... 
Iteration: 1626970262, states[0] = -6.596155, states[40]= 0.003547
Saving checkpoint... 
Iteration: 1640872974, states[0] = -94.988898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653894703, states[0] = -95.164400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667448044, states[0] = 8.706255, states[40]= 0.005972
Saving checkpoint... 
Iteration: 1680517003, states[0] = -95.080204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1693295725, states[0] = -34.149336, states[40]= 0.000296
Saving checkpoint... 
Iteration: 1706024477, states[0] = -95.091974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1718886134, states[0] = -95.021212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1732206526, states[0] = 29.706239, states[40]= 0.101314
Saving checkpoint... 
Iteration: 1745161525, states[0] = 0.407678, states[40]= 0.005021
Saving checkpoint... 
Iteration: 1758040239, states[0] = 12.878162, states[40]= 0.006480
Saving checkpoint... 
Iteration: 1771518764, states[0] = 22.583483, states[40]= 0.013481
Saving checkpoint... 
Iteration: 1784460723, states[0] = 0.964078, states[40]= 0.005107
Saving checkpoint... 
Iteration: 1797253422, states[0] = -95.128969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1809469185, states[0] = -94.905596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822228459, states[0] = -94.740105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834584222, states[0] = -7.749209, states[40]= 0.002925
Saving checkpoint... 
Iteration: 1847164683, states[0] = -93.660540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1859848177, states[0] = -94.827997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1873006294, states[0] = 29.018186, states[40]= 0.114937
Saving checkpoint... 
Iteration: 1886046644, states[0] = 13.100126, states[40]= 0.005406
Saving checkpoint... 
Iteration: 1899259145, states[0] = -94.747303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1912356486, states[0] = -94.820629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1924862856, states[0] = -94.822457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1937381439, states[0] = -94.829059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1950352766, states[0] = -94.816700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963428890, states[0] = -94.841891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976003341, states[0] = 38.166579, states[40]= 0.131836
Saving checkpoint... 
Iteration: 1988898618, states[0] = -94.833461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002057878, states[0] = 8.404019, states[40]= 0.005132
Saving checkpoint... 
Iteration: 2015304018, states[0] = -94.786114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028282518, states[0] = -94.767652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2040894351, states[0] = -94.831807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2054207707, states[0] = -94.661750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067009665, states[0] = 25.885389, states[40]= 0.056942
Saving checkpoint... 
Iteration: 2079552932, states[0] = 10.564849, states[40]= 0.005239
Saving checkpoint... 
Iteration: 2092293749, states[0] = -94.777618, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.728672
 - CaMKt in component CaMK (millimolar): 0.006825
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.865391
 - nass in component intracellular_ions (millimolar): 6.865450
 - ki in component intracellular_ions (millimolar): 145.113468
 - kss in component intracellular_ions (millimolar): 145.113449
 - cansr in component intracellular_ions (millimolar): 1.310303
 - cajsr in component intracellular_ions (millimolar): 1.272915
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003682
 - hf in component INa (dimensionless): 0.876963
 - hs in component INa (dimensionless): 0.876959
 - j in component INa (dimensionless): 0.876929
 - hsp in component INa (dimensionless): 0.720132
 - jp in component INa (dimensionless): 0.876909
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.705775
 - hLp in component INaL (dimensionless): 0.448114
 - a in component Ito (dimensionless): 0.000631
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.622198
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.696419
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933860
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999883
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001609
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.345661
 - xs1 in component IKs (dimensionless): 0.239780
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997382
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:33:11 (24033): called boinc_finish(0)

</stderr_txt>
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