𝕏

Task 55251348

Name HuVeMOp_20240627011117817647_ORdGradInc_k_24-BASE_MID-conf_485_2
Workunit 26070955
Created 28 Jun 2024, 10:58:13 UTC
Sent 29 Jun 2024, 9:21:56 UTC
Report deadline 2 Jul 2024, 9:21:56 UTC
Received 30 Jun 2024, 11:27:45 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 72956
Run time 1 hours 41 min 24 sec
CPU time 1 hours 20 min 40 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 5.56 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.86 MB
Peak swap size 4.13 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627011117817647_ORdGradInc_k_24-BASE_MID-conf_485.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627011117817647_ORdGradInc_k_24-BASE_MID-conf_485_2_r1150747027_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627011117817647_ORdGradInc_k_24-BASE_MID-conf_485_2_r1150747027_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 96.832252
     * GNaL_b in INaL: 0.009098
     * Gto_b in Ito: 0.084901
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031902
     * GKs_b in IKs: 0.001915
     * GK1_b in IK1: 0.169107
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 64.810173
     * GKb_b in IKb: 0.003816
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034195
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8361458, states[0] = -86.825058, states[40]= 0.000001
Saving checkpoint... 
Iteration: 17066909, states[0] = 24.031648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25660276, states[0] = -24.639246, states[40]= 0.000779
Saving checkpoint... 
Iteration: 34888176, states[0] = -86.891262, states[40]= 0.000002
Saving checkpoint... 
Iteration: 42488306, states[0] = -86.971410, states[40]= 0.000002
Saving checkpoint... 
Iteration: 51397402, states[0] = -86.927489, states[40]= 0.000002
Saving checkpoint... 
Iteration: 60074437, states[0] = 19.147123, states[40]= 0.000003
Saving checkpoint... 
Iteration: 69260887, states[0] = -86.612376, states[40]= 0.000001
Saving checkpoint... 
Iteration: 76679133, states[0] = -51.098840, states[40]= 0.000182
Saving checkpoint... 
Iteration: 85632248, states[0] = -12.629609, states[40]= 0.000334
Saving checkpoint... 
Iteration: 93602228, states[0] = 5.988542, states[40]= 0.000074
Saving checkpoint... 
Iteration: 102369020, states[0] = -86.934123, states[40]= 0.000002
Saving checkpoint... 
Iteration: 110976271, states[0] = -87.021312, states[40]= 0.000002
Saving checkpoint... 
Iteration: 119571783, states[0] = 19.429474, states[40]= 0.000003
Saving checkpoint... 
Iteration: 127916378, states[0] = -86.989806, states[40]= 0.000002
Saving checkpoint... 
Iteration: 136287756, states[0] = -86.755023, states[40]= 0.000002
Saving checkpoint... 
Iteration: 144870782, states[0] = -86.943798, states[40]= 0.000002
Saving checkpoint... 
Iteration: 153265154, states[0] = -86.662578, states[40]= 0.000001
Saving checkpoint... 
Iteration: 161938638, states[0] = -87.007435, states[40]= 0.000002
Saving checkpoint... 
Iteration: 170317278, states[0] = -86.845105, states[40]= 0.000002
Saving checkpoint... 
Iteration: 179172111, states[0] = -47.455062, states[40]= 0.000308
Saving checkpoint... 
Iteration: 187221345, states[0] = -86.388401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195610142, states[0] = 1.177190, states[40]= 0.000171
Saving checkpoint... 
Iteration: 204158520, states[0] = -34.813980, states[40]= 0.000986
Saving checkpoint... 
Iteration: 212737071, states[0] = -86.502762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 221894902, states[0] = -86.970512, states[40]= 0.000002
Saving checkpoint... 
Iteration: 230803846, states[0] = -86.806230, states[40]= 0.000002
Saving checkpoint... 
Iteration: 239882734, states[0] = -86.956238, states[40]= 0.000002
Saving checkpoint... 
Iteration: 249945018, states[0] = -87.007646, states[40]= 0.000002
Saving checkpoint... 
Iteration: 258237927, states[0] = -86.505741, states[40]= 0.000001
Saving checkpoint... 
Iteration: 267386634, states[0] = -86.958988, states[40]= 0.000002
Saving checkpoint... 
Iteration: 275583866, states[0] = 14.086155, states[40]= 0.000013
Saving checkpoint... 
Iteration: 284171835, states[0] = -47.343476, states[40]= 0.000312
Saving checkpoint... 
Iteration: 292058238, states[0] = 24.440918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300750504, states[0] = -86.579883, states[40]= 0.000001
Saving checkpoint... 
Iteration: 308317481, states[0] = -86.838264, states[40]= 0.000002
Saving checkpoint... 
Iteration: 316591620, states[0] = 10.537148, states[40]= 0.000031
Saving checkpoint... 
Iteration: 324602835, states[0] = 5.056826, states[40]= 0.000093
Saving checkpoint... 
Iteration: 333715911, states[0] = -86.328468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341709656, states[0] = -86.205961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349871373, states[0] = -86.934924, states[40]= 0.000002
Saving checkpoint... 
Iteration: 357951267, states[0] = -87.004006, states[40]= 0.000002
Saving checkpoint... 
Iteration: 365774361, states[0] = -86.692740, states[40]= 0.000001
Saving checkpoint... 
Iteration: 374453843, states[0] = -87.004256, states[40]= 0.000002
Saving checkpoint... 
Iteration: 382788649, states[0] = -86.747002, states[40]= 0.000002
Saving checkpoint... 
Iteration: 391051850, states[0] = 26.588782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399831927, states[0] = -86.865168, states[40]= 0.000002
Saving checkpoint... 
Iteration: 408974092, states[0] = -87.011305, states[40]= 0.000002
Saving checkpoint... 
Iteration: 417253114, states[0] = -86.586400, states[40]= 0.000001
Saving checkpoint... 
Iteration: 425049042, states[0] = 27.456773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434058561, states[0] = 24.329332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442527425, states[0] = 31.790966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450887652, states[0] = -86.947782, states[40]= 0.000002
Saving checkpoint... 
Iteration: 458854188, states[0] = -86.902306, states[40]= 0.000002
Saving checkpoint... 
Iteration: 466425810, states[0] = -86.980866, states[40]= 0.000002
Saving checkpoint... 
Iteration: 474295695, states[0] = -86.764663, states[40]= 0.000002
Saving checkpoint... 
Iteration: 482067977, states[0] = 20.795227, states[40]= 0.000002
Saving checkpoint... 
Iteration: 490017705, states[0] = 31.270236, states[40]= -0.000000
Saving checkpoint... 
Iteration: 497260822, states[0] = -86.621290, states[40]= 0.000001
Saving checkpoint... 
Iteration: 504798396, states[0] = -86.771217, states[40]= 0.000002
Saving checkpoint... 
Iteration: 514516555, states[0] = 30.993730, states[40]= -0.000000
Saving checkpoint... 
Iteration: 523867344, states[0] = -86.917642, states[40]= 0.000002
Saving checkpoint... 
Iteration: 532900406, states[0] = -86.955311, states[40]= 0.000002
Saving checkpoint... 
Iteration: 542520277, states[0] = 31.685699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552877797, states[0] = -86.929374, states[40]= 0.000002
Saving checkpoint... 
Iteration: 562860356, states[0] = -86.904872, states[40]= 0.000002
Saving checkpoint... 
Iteration: 572514942, states[0] = 30.489528, states[40]= -0.000000
Saving checkpoint... 
Iteration: 582033192, states[0] = 31.158606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591651199, states[0] = -28.948598, states[40]= 0.001160
Saving checkpoint... 
Iteration: 601161650, states[0] = -37.560223, states[40]= 0.000810
Saving checkpoint... 
Iteration: 610045413, states[0] = 28.502103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619014783, states[0] = 30.432662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627309564, states[0] = -86.795765, states[40]= 0.000002
Saving checkpoint... 
Iteration: 635781247, states[0] = -86.702136, states[40]= 0.000001
Saving checkpoint... 
Iteration: 643268611, states[0] = -86.648407, states[40]= 0.000001
Saving checkpoint... 
Iteration: 651257645, states[0] = -86.594458, states[40]= 0.000001
Saving checkpoint... 
Iteration: 659652752, states[0] = -30.147947, states[40]= 0.001161
Saving checkpoint... 
Iteration: 666899814, states[0] = -86.945709, states[40]= 0.000002
Saving checkpoint... 
Iteration: 675703026, states[0] = -85.397345, states[40]= 0.000001
Saving checkpoint... 
Iteration: 684529526, states[0] = 31.624794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693116319, states[0] = -2.530794, states[40]= 0.000257
Saving checkpoint... 
Iteration: 702596554, states[0] = 8.197445, states[40]= 0.000051
Saving checkpoint... 
Iteration: 712474373, states[0] = -86.990973, states[40]= 0.000002
Saving checkpoint... 
Iteration: 722295414, states[0] = -86.746774, states[40]= 0.000002
Saving checkpoint... 
Iteration: 731735954, states[0] = -86.459776, states[40]= 0.000001
Saving checkpoint... 
Iteration: 742635828, states[0] = -17.348247, states[40]= 0.000403
Saving checkpoint... 
Iteration: 751404689, states[0] = -86.944595, states[40]= 0.000002
Saving checkpoint... 
Iteration: 760592228, states[0] = 10.265153, states[40]= 0.000033
Saving checkpoint... 
Iteration: 770080094, states[0] = 15.764217, states[40]= 0.000008
Saving checkpoint... 
Iteration: 779562528, states[0] = 22.895104, states[40]= 0.000001
Saving checkpoint... 
Iteration: 787530271, states[0] = 31.549315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798074687, states[0] = 18.074543, states[40]= 0.000004
Saving checkpoint... 
Iteration: 807840318, states[0] = -86.854252, states[40]= 0.000002
Saving checkpoint... 
Iteration: 817428838, states[0] = -86.959337, states[40]= 0.000002
Saving checkpoint... 
Iteration: 827460121, states[0] = -86.976885, states[40]= 0.000002
Saving checkpoint... 
Iteration: 837489437, states[0] = -86.988235, states[40]= 0.000002
Saving checkpoint... 
Iteration: 846791876, states[0] = -86.726449, states[40]= 0.000002
Saving checkpoint... 
Iteration: 857670255, states[0] = -45.669788, states[40]= 0.000373
Saving checkpoint... 
Iteration: 867628165, states[0] = -11.143724, states[40]= 0.000344
Saving checkpoint... 
Iteration: 877877598, states[0] = -86.907158, states[40]= 0.000002
Saving checkpoint... 
Iteration: 888563123, states[0] = 22.675155, states[40]= 0.000001
Saving checkpoint... 
Iteration: 899109220, states[0] = 1.686444, states[40]= 0.000158
Saving checkpoint... 
Iteration: 907353097, states[0] = -86.870117, states[40]= 0.000002
Saving checkpoint... 
Iteration: 917084588, states[0] = 13.779161, states[40]= 0.000014
Saving checkpoint... 
Iteration: 928789033, states[0] = -86.710990, states[40]= 0.000002
Saving checkpoint... 
Iteration: 938901500, states[0] = -86.928991, states[40]= 0.000002
Saving checkpoint... 
Iteration: 948285312, states[0] = -86.696175, states[40]= 0.000002
Saving checkpoint... 
Iteration: 959104457, states[0] = 4.244651, states[40]= 0.000106
Saving checkpoint... 
Iteration: 970732141, states[0] = -86.416864, states[40]= 0.000001
Saving checkpoint... 
Iteration: 979722363, states[0] = -86.342642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990731992, states[0] = -86.414412, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1001069646, states[0] = 20.144995, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1011139561, states[0] = -20.230820, states[40]= 0.000538
Saving checkpoint... 
Iteration: 1022172799, states[0] = -48.262326, states[40]= 0.000277
Saving checkpoint... 
Iteration: 1030380659, states[0] = -86.900587, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1038982526, states[0] = -86.972211, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1047776843, states[0] = -86.656239, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1057909122, states[0] = -86.927819, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1067113151, states[0] = -0.559367, states[40]= 0.000210
Saving checkpoint... 
Iteration: 1076316045, states[0] = -86.782329, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1086896976, states[0] = -86.914628, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1098193726, states[0] = -76.117436, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1109551852, states[0] = 26.606895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119283526, states[0] = -86.677770, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1129883145, states[0] = -86.896819, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1139972585, states[0] = -86.961512, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1150621828, states[0] = -6.248396, states[40]= 0.000318
Saving checkpoint... 
Iteration: 1161412566, states[0] = -86.923784, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1172131082, states[0] = -13.478459, states[40]= 0.000346
Saving checkpoint... 
Iteration: 1182533764, states[0] = 31.086330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192588324, states[0] = 12.091997, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1203171131, states[0] = -46.517417, states[40]= 0.000337
Saving checkpoint... 
Iteration: 1212937316, states[0] = -86.938303, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1224331194, states[0] = -86.807627, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1235457637, states[0] = -86.948260, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1246172219, states[0] = -47.631598, states[40]= 0.000297
Saving checkpoint... 
Iteration: 1257780355, states[0] = -86.656034, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1268878112, states[0] = -86.881415, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1279348104, states[0] = -86.836503, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1288058834, states[0] = 24.254559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297215891, states[0] = -86.260040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306026500, states[0] = 31.865960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316432699, states[0] = -86.928365, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1327655964, states[0] = -32.658041, states[40]= 0.001078
Saving checkpoint... 
Iteration: 1337066553, states[0] = 21.375603, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1348326225, states[0] = -86.788290, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1357892968, states[0] = -86.892237, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1368243030, states[0] = -86.461524, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1380413338, states[0] = -86.909667, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1390069072, states[0] = 20.384597, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1400809321, states[0] = -86.742435, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1410815184, states[0] = -86.757415, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1420911008, states[0] = -86.905017, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1431131331, states[0] = -13.657953, states[40]= 0.000345
Saving checkpoint... 
Iteration: 1441161235, states[0] = -37.110745, states[40]= 0.000825
Saving checkpoint... 
Iteration: 1452216120, states[0] = -86.251700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461968586, states[0] = -86.938154, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1472928965, states[0] = -86.915308, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1483380631, states[0] = -86.869986, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1492253307, states[0] = -86.513203, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.823027
 - CaMKt in component CaMK (millimolar): 0.026606
 - cass in component intracellular_ions (millimolar): 0.000096
 - nai in component intracellular_ions (millimolar): 8.261171
 - nass in component intracellular_ions (millimolar): 8.261332
 - ki in component intracellular_ions (millimolar): 143.015423
 - kss in component intracellular_ions (millimolar): 143.015383
 - cansr in component intracellular_ions (millimolar): 2.153054
 - cajsr in component intracellular_ions (millimolar): 2.094032
 - cai in component intracellular_ions (millimolar): 0.000099
 - m in component INa (dimensionless): 0.008166
 - hf in component INa (dimensionless): 0.660381
 - hs in component INa (dimensionless): 0.660352
 - j in component INa (dimensionless): 0.660184
 - hsp in component INa (dimensionless): 0.412374
 - jp in component INa (dimensionless): 0.660062
 - mL in component INaL (dimensionless): 0.000230
 - hL in component INaL (dimensionless): 0.455797
 - hLp in component INaL (dimensionless): 0.221110
 - a in component Ito (dimensionless): 0.001075
 - iF in component Ito (dimensionless): 0.999464
 - iS in component Ito (dimensionless): 0.529602
 - ap in component Ito (dimensionless): 0.000548
 - iFp in component Ito (dimensionless): 0.999464
 - iSp in component Ito (dimensionless): 0.572965
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.873555
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999579
 - jca in component ICaL (dimensionless): 0.999934
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004313
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.512763
 - xs1 in component IKs (dimensionless): 0.339147
 - xs2 in component IKs (dimensionless): 0.000217
 - xk1 in component IK1 (dimensionless): 0.997026
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
13:13:50 (22213): called boinc_finish(0)

</stderr_txt>
]]>


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