𝕏

Task 55250967

Name HuVeMOp_20240624185102527553_ORdGradInc_k_24-CLVPET-conf_677_3
Workunit 25918676
Created 28 Jun 2024, 9:25:47 UTC
Sent 29 Jun 2024, 9:21:56 UTC
Report deadline 2 Jul 2024, 12:14:44 UTC
Received 30 Jun 2024, 12:51:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 72956
Run time 1 hours 50 min 30 sec
CPU time 1 hours 27 min 59 sec
Validate state Valid
Credit 55.16
Device peak FLOPS 5.56 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.79 MB
Peak swap size 4.13 GB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-CLVPET-conf_677.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-CLVPET-conf_677_3_r821516268_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-CLVPET-conf_677_3_r821516268_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.059731
     * GNaL_b in INaL: 0.005755
     * Gto_b in Ito: 0.071307
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033997
     * GKs_b in IKs: 0.001834
     * GK1_b in IK1: 0.143393
     * Gncx_b in INaCa_i: 0.000951
     * Pnak_b in INaK: 64.507262
     * GKb_b in IKb: 0.003894
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.051951
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7478354, states[0] = -94.831650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16149312, states[0] = -71.684974, states[40]= 0.000002
Saving checkpoint... 
Iteration: 24351042, states[0] = -94.713046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32883199, states[0] = -94.732083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41975583, states[0] = -94.770541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51218165, states[0] = -94.424602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61005560, states[0] = 31.928291, states[40]= 0.207922
Saving checkpoint... 
Iteration: 71380938, states[0] = -94.729443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79810758, states[0] = -94.657885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88905311, states[0] = -94.745134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96747773, states[0] = -94.526815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105779687, states[0] = -94.604965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113702556, states[0] = -94.359599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121118383, states[0] = -36.185160, states[40]= 0.000514
Saving checkpoint... 
Iteration: 128738248, states[0] = -94.498192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136652538, states[0] = -74.484155, states[40]= 0.000001
Saving checkpoint... 
Iteration: 144973667, states[0] = -94.772479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153296273, states[0] = -94.636255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161174704, states[0] = -93.908500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168900272, states[0] = -94.743172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177070378, states[0] = 7.008354, states[40]= 0.004725
Saving checkpoint... 
Iteration: 185634697, states[0] = -53.618106, states[40]= 0.000048
Saving checkpoint... 
Iteration: 194834903, states[0] = -94.689908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203758006, states[0] = -94.555428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212325643, states[0] = -94.678943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221084644, states[0] = -2.300012, states[40]= 0.004384
Saving checkpoint... 
Iteration: 229740809, states[0] = -94.506319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237759175, states[0] = -94.558336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245841630, states[0] = -94.697055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254038432, states[0] = 21.399120, states[40]= 0.002405
Saving checkpoint... 
Iteration: 262336194, states[0] = -94.691146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271164736, states[0] = -90.452797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279353452, states[0] = -94.708570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287507836, states[0] = 29.732839, states[40]= 0.098197
Saving checkpoint... 
Iteration: 295050770, states[0] = 16.377358, states[40]= 0.003352
Saving checkpoint... 
Iteration: 303312250, states[0] = -94.660803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311907830, states[0] = -94.746909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318947828, states[0] = -94.764185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326795095, states[0] = -94.633785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336409734, states[0] = -94.747813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345470414, states[0] = -94.771103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354350501, states[0] = -94.705521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363242024, states[0] = -94.509609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372395579, states[0] = -94.739792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382211927, states[0] = -94.400247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392621942, states[0] = -39.898802, states[40]= 0.000333
Saving checkpoint... 
Iteration: 401387075, states[0] = -94.734364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411280761, states[0] = -94.606767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420262560, states[0] = -94.566151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429826953, states[0] = -94.679769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438518169, states[0] = 27.838886, states[40]= 0.004338
Saving checkpoint... 
Iteration: 447610805, states[0] = -28.437841, states[40]= 0.000963
Saving checkpoint... 
Iteration: 457061142, states[0] = 11.721099, states[40]= 0.004186
Saving checkpoint... 
Iteration: 465462942, states[0] = -94.768513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471965360, states[0] = -94.769200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479481388, states[0] = -94.773445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487504890, states[0] = 33.202295, states[40]= 0.258461
Saving checkpoint... 
Iteration: 495011499, states[0] = 28.823655, states[40]= 0.029323
Saving checkpoint... 
Iteration: 504677766, states[0] = -94.098514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512756311, states[0] = -94.549870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523257651, states[0] = -94.553339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532444968, states[0] = -94.762369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541688006, states[0] = -94.280770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550459640, states[0] = -94.767193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560117573, states[0] = -35.372030, states[40]= 0.000560
Saving checkpoint... 
Iteration: 570518596, states[0] = 27.752566, states[40]= 0.003959
Saving checkpoint... 
Iteration: 580282986, states[0] = -94.610551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590885821, states[0] = -94.732826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601681138, states[0] = -94.198325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612510557, states[0] = 28.956690, states[40]= 0.039878
Saving checkpoint... 
Iteration: 621922412, states[0] = -94.752890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631752543, states[0] = -94.539265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641117951, states[0] = -35.760668, states[40]= 0.000538
Saving checkpoint... 
Iteration: 650181088, states[0] = -94.197110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660568421, states[0] = 8.066489, states[40]= 0.004639
Saving checkpoint... 
Iteration: 669696764, states[0] = -94.330658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678733256, states[0] = -94.480005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688304516, states[0] = -94.647823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698174916, states[0] = -93.925083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707466484, states[0] = -94.768637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717301100, states[0] = -94.642308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726954019, states[0] = -94.764742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735340989, states[0] = -94.694547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744400953, states[0] = -94.741520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752326329, states[0] = -94.677785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761566160, states[0] = 9.246412, states[40]= 0.004518
Saving checkpoint... 
Iteration: 770166633, states[0] = -91.752034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779200524, states[0] = -94.348266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789084621, states[0] = -2.281120, states[40]= 0.004387
Saving checkpoint... 
Iteration: 798603800, states[0] = -21.206608, states[40]= 0.001204
Saving checkpoint... 
Iteration: 808297047, states[0] = -94.635285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818935323, states[0] = -94.757640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829626608, states[0] = -44.837582, states[40]= 0.000174
Saving checkpoint... 
Iteration: 839540647, states[0] = 20.532101, states[40]= 0.002557
Saving checkpoint... 
Iteration: 848398348, states[0] = -94.739632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859048406, states[0] = 17.376141, states[40]= 0.003157
Saving checkpoint... 
Iteration: 869252575, states[0] = -94.538449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877036446, states[0] = 22.162712, states[40]= 0.002279
Saving checkpoint... 
Iteration: 888145285, states[0] = -65.398448, states[40]= 0.000007
Saving checkpoint... 
Iteration: 897441532, states[0] = -94.759736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908897070, states[0] = -94.738655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918520078, states[0] = 27.428839, states[40]= 0.003013
Saving checkpoint... 
Iteration: 928671826, states[0] = -93.537532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939104850, states[0] = -22.300834, states[40]= 0.001164
Saving checkpoint... 
Iteration: 950332911, states[0] = -94.684854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959502312, states[0] = 43.781638, states[40]= 0.458170
Saving checkpoint... 
Iteration: 970731483, states[0] = -94.472815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981157419, states[0] = -81.504453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992008507, states[0] = 29.445132, states[40]= 0.078557
Saving checkpoint... 
Iteration: 1002551698, states[0] = 15.981029, states[40]= 0.003430
Saving checkpoint... 
Iteration: 1013587027, states[0] = -4.266182, states[40]= 0.004035
Saving checkpoint... 
Iteration: 1022698768, states[0] = -94.339031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032469491, states[0] = -94.768262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042829671, states[0] = -94.680724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053423139, states[0] = -94.751593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064454440, states[0] = -94.763609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073698771, states[0] = -94.338849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085722298, states[0] = -94.439041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096845827, states[0] = -94.698150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105648242, states[0] = -68.929966, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1115839483, states[0] = -94.691510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126716988, states[0] = -94.418157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137502142, states[0] = 44.786534, states[40]= 0.448520
Saving checkpoint... 
Iteration: 1149157206, states[0] = -81.189727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161115706, states[0] = -33.453053, states[40]= 0.000676
Saving checkpoint... 
Iteration: 1172059377, states[0] = 12.552645, states[40]= 0.004054
Saving checkpoint... 
Iteration: 1184284532, states[0] = -94.611271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195012406, states[0] = 28.712757, states[40]= 0.021900
Saving checkpoint... 
Iteration: 1206165646, states[0] = -91.125531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215051976, states[0] = 15.861687, states[40]= 0.003453
Saving checkpoint... 
Iteration: 1225413938, states[0] = -94.746593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236788035, states[0] = -94.617710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246560128, states[0] = 12.201621, states[40]= 0.004111
Saving checkpoint... 
Iteration: 1258293127, states[0] = -94.626834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267333951, states[0] = -94.684842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277863864, states[0] = -94.713931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289770709, states[0] = -94.582031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300994145, states[0] = -94.773260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311147710, states[0] = -68.277673, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1320819215, states[0] = -94.666547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331933945, states[0] = -94.755156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343313401, states[0] = -94.658505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355316357, states[0] = -94.662567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366055809, states[0] = 14.180022, states[40]= 0.003771
Saving checkpoint... 
Iteration: 1376874270, states[0] = -94.721745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387290906, states[0] = -94.622392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398586603, states[0] = -3.903599, states[40]= 0.004106
Saving checkpoint... 
Iteration: 1407235107, states[0] = -94.483446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418721979, states[0] = -94.436553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430146633, states[0] = -66.981004, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1440030778, states[0] = 24.238245, states[40]= 0.001988
Saving checkpoint... 
Iteration: 1449844333, states[0] = -94.695309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460422332, states[0] = -94.749694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471365734, states[0] = -94.714737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481348136, states[0] = -94.698982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490151624, states[0] = -73.258662, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1500266011, states[0] = -85.715724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510935477, states[0] = -94.936581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521424570, states[0] = -53.440622, states[40]= 0.000070
Saving checkpoint... 
Iteration: 1531215937, states[0] = -94.800486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541068038, states[0] = -94.492276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1553090266, states[0] = -94.514071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1563313053, states[0] = -94.355572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573861040, states[0] = -94.510051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584402879, states[0] = -94.393773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595193243, states[0] = -93.209884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606602391, states[0] = -94.369307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617060257, states[0] = -94.360712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628039110, states[0] = -94.264572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636712288, states[0] = -94.257167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647256420, states[0] = -94.243323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659177651, states[0] = -94.242033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669563407, states[0] = -94.232962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679084152, states[0] = -94.235306, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.102121
 - CaMKt in component CaMK (millimolar): 0.001149
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.498750
 - nass in component intracellular_ions (millimolar): 6.498838
 - ki in component intracellular_ions (millimolar): 145.394890
 - kss in component intracellular_ions (millimolar): 145.394878
 - cansr in component intracellular_ions (millimolar): 1.588808
 - cajsr in component intracellular_ions (millimolar): 1.588766
 - cai in component intracellular_ions (millimolar): 0.000091
 - m in component INa (dimensionless): 0.003923
 - hf in component INa (dimensionless): 0.865415
 - hs in component INa (dimensionless): 0.865416
 - j in component INa (dimensionless): 0.865417
 - hsp in component INa (dimensionless): 0.698948
 - jp in component INa (dimensionless): 0.865418
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707579
 - hLp in component INaL (dimensionless): 0.513862
 - a in component Ito (dimensionless): 0.000658
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.997754
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999247
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998939
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003183
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001855
 - xs1 in component IKs (dimensionless): 0.021527
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997539
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:50:31 (23918): called boinc_finish(0)

</stderr_txt>
]]>


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