𝕏

Task 55250580

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-BASE_MID-conf_162_2
Workunit 26119891
Created 28 Jun 2024, 8:00:09 UTC
Sent 29 Jun 2024, 9:17:11 UTC
Report deadline 2 Jul 2024, 9:17:11 UTC
Received 30 Jun 2024, 4:35:16 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233433
Run time 2 hours 9 min 24 sec
CPU time 2 hours 4 min 20 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 3.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.66 MB
Peak swap size 32.60 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-BASE_MID-conf_162.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-BASE_MID-conf_162_2_r1735516181_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-BASE_MID-conf_162_2_r1735516181_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 107.168723
     * GNaL_b in INaL: 0.007588
     * Gto_b in Ito: 0.096522
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032928
     * GKs_b in IKs: 0.002070
     * GK1_b in IK1: 0.157642
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 69.178110
     * GKb_b in IKb: 0.003745
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044118
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11365989, states[0] = -86.724803, states[40]= 0.000001
Saving checkpoint... 
Iteration: 21141067, states[0] = -14.256529, states[40]= 0.000188
Saving checkpoint... 
Iteration: 32561759, states[0] = 24.271556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41092268, states[0] = 11.368219, states[40]= 0.000018


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-BASE_MID-conf_162.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-BASE_MID-conf_162_2_r1735516181_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-BASE_MID-conf_162_2_r1735516181_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 107.168723
     * GNaL_b in INaL: 0.007588
     * Gto_b in Ito: 0.096522
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032928
     * GKs_b in IKs: 0.002070
     * GK1_b in IK1: 0.157642
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 69.178110
     * GKb_b in IKb: 0.003745
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044118
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 41092268
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 11.368219 (After loading)
 - states[40]: 0.000018 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 50719049, states[0] = -86.197311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60787913, states[0] = -86.630507, states[40]= 0.000001
Saving checkpoint... 
Iteration: 70562666, states[0] = 22.813177, states[40]= 0.000001
Saving checkpoint... 
Iteration: 85199290, states[0] = -85.031251, states[40]= 0.000001
Saving checkpoint... 
Iteration: 100163285, states[0] = -44.188480, states[40]= 0.000329
Saving checkpoint... 
Iteration: 113987852, states[0] = -86.958435, states[40]= 0.000002
Saving checkpoint... 
Iteration: 121895161, states[0] = -86.899799, states[40]= 0.000002
Saving checkpoint... 
Iteration: 132710413, states[0] = -86.173382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143427181, states[0] = -86.930857, states[40]= 0.000002
Saving checkpoint... 
Iteration: 156377213, states[0] = -86.882008, states[40]= 0.000002
Saving checkpoint... 
Iteration: 171261403, states[0] = -86.557712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 185853663, states[0] = -86.846617, states[40]= 0.000002
Saving checkpoint... 
Iteration: 200408209, states[0] = -86.915077, states[40]= 0.000002
Saving checkpoint... 
Iteration: 215308936, states[0] = -86.744537, states[40]= 0.000002
Saving checkpoint... 
Iteration: 230101944, states[0] = 4.174470, states[40]= 0.000103
Saving checkpoint... 
Iteration: 244980483, states[0] = -86.957238, states[40]= 0.000002
Saving checkpoint... 
Iteration: 259910626, states[0] = -86.913772, states[40]= 0.000002
Saving checkpoint... 
Iteration: 274738107, states[0] = -86.410624, states[40]= 0.000001
Saving checkpoint... 
Iteration: 289502933, states[0] = 15.692349, states[40]= 1.505736
Saving checkpoint... 
Iteration: 304393334, states[0] = -86.893829, states[40]= 0.000002
Saving checkpoint... 
Iteration: 319175157, states[0] = -58.772779, states[40]= 0.000059
Saving checkpoint... 
Iteration: 333635338, states[0] = -20.993709, states[40]= 0.000446
Saving checkpoint... 
Iteration: 348532825, states[0] = 30.366438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363301266, states[0] = -86.711163, states[40]= 0.000002
Saving checkpoint... 
Iteration: 378099099, states[0] = 5.721788, states[40]= 0.000080
Saving checkpoint... 
Iteration: 393029558, states[0] = 30.706246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407975749, states[0] = -86.944164, states[40]= 0.000002
Saving checkpoint... 
Iteration: 422907654, states[0] = -86.899811, states[40]= 0.000002
Saving checkpoint... 
Iteration: 437739669, states[0] = -86.409743, states[40]= 0.000001
Saving checkpoint... 
Iteration: 452453510, states[0] = -86.930461, states[40]= 0.000002
Saving checkpoint... 
Iteration: 467217131, states[0] = -86.230073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481459074, states[0] = -86.931356, states[40]= 0.000002
Saving checkpoint... 
Iteration: 496217799, states[0] = -86.234075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 511043781, states[0] = 28.263443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525674931, states[0] = -58.471581, states[40]= 0.000061
Saving checkpoint... 
Iteration: 540276706, states[0] = -86.606713, states[40]= 0.000002
Saving checkpoint... 
Iteration: 555139508, states[0] = -24.349401, states[40]= 0.000646
Saving checkpoint... 
Iteration: 569916146, states[0] = -86.897001, states[40]= 0.000002
Saving checkpoint... 
Iteration: 584137067, states[0] = -22.381788, states[40]= 0.000522
Saving checkpoint... 
Iteration: 598430406, states[0] = -86.905961, states[40]= 0.000002
Saving checkpoint... 
Iteration: 612415467, states[0] = -86.893467, states[40]= 0.000002
Saving checkpoint... 
Iteration: 626661924, states[0] = -44.278761, states[40]= 0.000338
Saving checkpoint... 
Iteration: 641079190, states[0] = 15.439265, states[40]= 0.000009
Saving checkpoint... 
Iteration: 652987976, states[0] = -86.931864, states[40]= 0.000002
Saving checkpoint... 
Iteration: 664849444, states[0] = -86.806890, states[40]= 0.000002
Saving checkpoint... 
Iteration: 676322074, states[0] = -86.748021, states[40]= 0.000002
Saving checkpoint... 
Iteration: 687564842, states[0] = 21.435628, states[40]= 0.000001
Saving checkpoint... 
Iteration: 698927235, states[0] = -86.896711, states[40]= 0.000002
Saving checkpoint... 
Iteration: 709817191, states[0] = -86.733124, states[40]= 0.000002
Saving checkpoint... 
Iteration: 720907016, states[0] = -86.878464, states[40]= 0.000002
Saving checkpoint... 
Iteration: 731587736, states[0] = 11.475917, states[40]= 0.000025
Saving checkpoint... 
Iteration: 742585768, states[0] = 12.412748, states[40]= 0.000020
Saving checkpoint... 
Iteration: 753466141, states[0] = -86.915906, states[40]= 0.000002
Saving checkpoint... 
Iteration: 764486834, states[0] = -86.923709, states[40]= 0.000002
Saving checkpoint... 
Iteration: 775318504, states[0] = -86.731924, states[40]= 0.000002
Saving checkpoint... 
Iteration: 786310947, states[0] = -86.710575, states[40]= 0.000002
Saving checkpoint... 
Iteration: 797461773, states[0] = -86.910743, states[40]= 0.000002
Saving checkpoint... 
Iteration: 808425575, states[0] = -86.887820, states[40]= 0.000002
Saving checkpoint... 
Iteration: 819456381, states[0] = -86.906467, states[40]= 0.000002
Saving checkpoint... 
Iteration: 830208432, states[0] = -86.100416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841148995, states[0] = -32.145889, states[40]= 0.000819
Saving checkpoint... 
Iteration: 852295422, states[0] = -86.657217, states[40]= 0.000002
Saving checkpoint... 
Iteration: 863460495, states[0] = -86.905550, states[40]= 0.000002
Saving checkpoint... 
Iteration: 874751011, states[0] = -86.451180, states[40]= 0.000001
Saving checkpoint... 
Iteration: 885816973, states[0] = -86.720152, states[40]= 0.000002
Saving checkpoint... 
Iteration: 896945509, states[0] = -86.895015, states[40]= 0.000002
Saving checkpoint... 
Iteration: 908037206, states[0] = 29.699859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919096416, states[0] = 7.157256, states[40]= 0.000061
Saving checkpoint... 
Iteration: 930344618, states[0] = -86.779357, states[40]= 0.000002
Saving checkpoint... 
Iteration: 940642529, states[0] = -26.744366, states[40]= 0.000773
Saving checkpoint... 
Iteration: 951632558, states[0] = -18.619630, states[40]= 0.000348
Saving checkpoint... 
Iteration: 962762962, states[0] = -86.511416, states[40]= 0.000001
Saving checkpoint... 
Iteration: 973810648, states[0] = -86.696504, states[40]= 0.000002
Saving checkpoint... 
Iteration: 984717396, states[0] = -86.194873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995656599, states[0] = -39.005976, states[40]= 0.000546
Saving checkpoint... 
Iteration: 1006699831, states[0] = -85.613813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017907079, states[0] = -86.857846, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1028916654, states[0] = -86.865470, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1040007789, states[0] = 24.477032, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1050411484, states[0] = -86.859542, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1061504408, states[0] = 18.521648, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1072754454, states[0] = -86.457200, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1083912787, states[0] = -86.858335, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1095040174, states[0] = 29.115849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106099282, states[0] = 5.654117, states[40]= 0.000079
Saving checkpoint... 
Iteration: 1117162699, states[0] = -45.008085, states[40]= 0.000310
Saving checkpoint... 
Iteration: 1128644108, states[0] = -28.012458, states[40]= 0.000816
Saving checkpoint... 
Iteration: 1139876755, states[0] = -86.815745, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1150628220, states[0] = -14.858892, states[40]= 0.000291
Saving checkpoint... 
Iteration: 1161831740, states[0] = -86.736663, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1172930245, states[0] = -86.865910, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1184202198, states[0] = -85.842793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195487600, states[0] = -86.894096, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1206773428, states[0] = -86.544812, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1218149037, states[0] = -32.144229, states[40]= 0.000814
Saving checkpoint... 
Iteration: 1229122724, states[0] = -10.074953, states[40]= 0.000289
Saving checkpoint... 
Iteration: 1240423766, states[0] = -86.856403, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1251548930, states[0] = 26.892455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262308425, states[0] = -86.669743, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1273526722, states[0] = 30.883180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284711372, states[0] = -86.110045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296063688, states[0] = 21.894459, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1307167571, states[0] = -50.095362, states[40]= 0.000175
Saving checkpoint... 
Iteration: 1318388266, states[0] = -86.817466, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1329706837, states[0] = -86.029997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340975860, states[0] = -86.879439, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1351985234, states[0] = -86.882376, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1362885276, states[0] = -86.810856, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1373408400, states[0] = -86.834297, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1384673763, states[0] = -56.960178, states[40]= 0.000074
Saving checkpoint... 
Iteration: 1395946198, states[0] = -86.860758, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1407100766, states[0] = 4.865322, states[40]= 0.000090
Saving checkpoint... 
Iteration: 1418155264, states[0] = -37.704748, states[40]= 0.000600
Saving checkpoint... 
Iteration: 1429283247, states[0] = -86.570997, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1440366829, states[0] = -86.780974, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1451593761, states[0] = 8.536832, states[40]= 0.000046
Saving checkpoint... 
Iteration: 1462636528, states[0] = -21.864657, states[40]= 0.000484
Saving checkpoint... 
Iteration: 1472914025, states[0] = -86.832321, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1484126026, states[0] = -12.907963, states[40]= 0.000285
Saving checkpoint... 
Iteration: 1495342282, states[0] = -86.735310, states[40]= 0.000002
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.753046
 - CaMKt in component CaMK (millimolar): 0.026982
 - cass in component intracellular_ions (millimolar): 0.000096
 - nai in component intracellular_ions (millimolar): 8.208870
 - nass in component intracellular_ions (millimolar): 8.209032
 - ki in component intracellular_ions (millimolar): 143.045578
 - kss in component intracellular_ions (millimolar): 143.045536
 - cansr in component intracellular_ions (millimolar): 2.184858
 - cajsr in component intracellular_ions (millimolar): 2.128463
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.008223
 - hf in component INa (dimensionless): 0.657797
 - hs in component INa (dimensionless): 0.657767
 - j in component INa (dimensionless): 0.657593
 - hsp in component INa (dimensionless): 0.409587
 - jp in component INa (dimensionless): 0.657467
 - mL in component INaL (dimensionless): 0.000233
 - hL in component INaL (dimensionless): 0.454669
 - hLp in component INaL (dimensionless): 0.221736
 - a in component Ito (dimensionless): 0.001080
 - iF in component Ito (dimensionless): 0.999457
 - iS in component Ito (dimensionless): 0.536134
 - ap in component Ito (dimensionless): 0.000550
 - iFp in component Ito (dimensionless): 0.999457
 - iSp in component Ito (dimensionless): 0.579919
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.879517
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999640
 - jca in component ICaL (dimensionless): 0.999943
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004436
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.505497
 - xs1 in component IKs (dimensionless): 0.330396
 - xs2 in component IKs (dimensionless): 0.000219
 - xk1 in component IK1 (dimensionless): 0.997043
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
00:02:29 (47873): called boinc_finish(0)

</stderr_txt>
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