𝕏

Task 55246574

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_1000-conf_696_1
Workunit 26236864
Created 28 Jun 2024, 6:19:10 UTC
Sent 29 Jun 2024, 8:43:56 UTC
Report deadline 2 Jul 2024, 8:43:56 UTC
Received 29 Jun 2024, 19:52:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 16 min 25 sec
CPU time 2 hours 11 min 49 sec
Validate state Valid
Credit 43.49
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.60 MB
Peak swap size 2.35 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_1000-conf_696.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_1000-conf_696_1_r716890317_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_1000-conf_696_1_r716890317_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.566155
     * GNaL_b in INaL: 0.005639
     * Gto_b in Ito: 0.080834
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030133
     * GKs_b in IKs: 0.001930
     * GK1_b in IK1: 0.179225
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 71.880871
     * GKb_b in IKb: 0.003675
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023214
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11248127, states[0] = -87.011895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22527953, states[0] = 19.439603, states[40]= 0.005806
Saving checkpoint... 
Iteration: 33797500, states[0] = -86.978460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45086344, states[0] = -8.107266, states[40]= 0.002706
Saving checkpoint... 
Iteration: 56290967, states[0] = -86.939795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67564869, states[0] = 5.696911, states[40]= 0.004657
Saving checkpoint... 
Iteration: 78782049, states[0] = -86.915835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89881757, states[0] = -86.971511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101188873, states[0] = -86.769244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112519532, states[0] = 22.405066, states[40]= 0.008903
Saving checkpoint... 
Iteration: 123764587, states[0] = -86.885681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135033027, states[0] = 18.716388, states[40]= 0.005311
Saving checkpoint... 
Iteration: 146286914, states[0] = -86.906173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157533248, states[0] = 18.658240, states[40]= 0.005295
Saving checkpoint... 
Iteration: 168777752, states[0] = -86.896401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180005412, states[0] = 26.499503, states[40]= 0.132622
Saving checkpoint... 
Iteration: 191041882, states[0] = 15.548771, states[40]= 0.004907
Saving checkpoint... 
Iteration: 202274999, states[0] = -86.892887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213534061, states[0] = 18.394884, states[40]= 0.005239
Saving checkpoint... 
Iteration: 224784684, states[0] = -86.902066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235977720, states[0] = -86.982698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247076877, states[0] = 0.034575, states[40]= 0.004163
Saving checkpoint... 
Iteration: 258316399, states[0] = -86.927082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269536900, states[0] = 17.397759, states[40]= 0.005079
Saving checkpoint... 
Iteration: 280759908, states[0] = -86.875863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291993317, states[0] = -86.984633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303270983, states[0] = -86.888230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314533703, states[0] = 18.521149, states[40]= 0.005264
Saving checkpoint... 
Iteration: 325765512, states[0] = -86.882245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336981032, states[0] = -86.982949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348238516, states[0] = -86.847700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359466033, states[0] = -86.980658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370705546, states[0] = -86.792824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381964665, states[0] = -86.980416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393220928, states[0] = -86.820114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404335024, states[0] = -86.938413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415600699, states[0] = -19.409068, states[40]= 0.000977
Saving checkpoint... 
Iteration: 426857572, states[0] = -86.949825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438105776, states[0] = -24.324830, states[40]= 0.000703
Saving checkpoint... 
Iteration: 449347859, states[0] = -86.945189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460591601, states[0] = -10.777388, states[40]= 0.002135
Saving checkpoint... 
Iteration: 471858858, states[0] = -86.950374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483124859, states[0] = -42.991856, states[40]= 0.000077
Saving checkpoint... 
Iteration: 494370860, states[0] = -86.955444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505632288, states[0] = -50.752933, states[40]= 0.000023
Saving checkpoint... 
Iteration: 516909158, states[0] = -86.968279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528135475, states[0] = -54.252689, states[40]= 0.000013
Saving checkpoint... 
Iteration: 539373655, states[0] = -86.956516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550520625, states[0] = 22.235035, states[40]= 0.008152
Saving checkpoint... 
Iteration: 561786027, states[0] = -86.902840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573039765, states[0] = 16.350731, states[40]= 0.004966
Saving checkpoint... 
Iteration: 584155394, states[0] = -81.025552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595424883, states[0] = -86.972298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606651794, states[0] = -76.043904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617819004, states[0] = -86.928487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629088513, states[0] = -8.093071, states[40]= 0.002683
Saving checkpoint... 
Iteration: 640338039, states[0] = -86.939924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651592013, states[0] = -11.149517, states[40]= 0.002064
Saving checkpoint... 
Iteration: 662816676, states[0] = -86.926903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674075090, states[0] = 1.050039, states[40]= 0.004283
Saving checkpoint... 
Iteration: 685349577, states[0] = -86.945874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696603756, states[0] = -22.370508, states[40]= 0.000797
Saving checkpoint... 
Iteration: 707690025, states[0] = -86.762866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718968352, states[0] = -86.980778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730234664, states[0] = -86.841746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741475195, states[0] = -86.981816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752738539, states[0] = -86.847444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763962828, states[0] = -86.979844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775222122, states[0] = -86.821846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786553774, states[0] = 10.888171, states[40]= 0.004780
Saving checkpoint... 
Iteration: 797698120, states[0] = -86.778505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808912128, states[0] = -86.968893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820134051, states[0] = -52.672756, states[40]= 0.000017
Saving checkpoint... 
Iteration: 831374282, states[0] = -86.956557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842622990, states[0] = -41.108638, states[40]= 0.000103
Saving checkpoint... 
Iteration: 853803519, states[0] = -86.917298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864899614, states[0] = -86.965256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876123552, states[0] = -41.672260, states[40]= 0.000095
Saving checkpoint... 
Iteration: 887347926, states[0] = -86.944918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898575519, states[0] = 0.811440, states[40]= 0.004256
Saving checkpoint... 
Iteration: 909815234, states[0] = -86.925753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921005640, states[0] = 26.185246, states[40]= 0.126914
Saving checkpoint... 
Iteration: 932238852, states[0] = -86.847772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943487813, states[0] = -86.983445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954744316, states[0] = -86.855454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965834764, states[0] = -86.937875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977047804, states[0] = 13.270466, states[40]= 0.004817
Saving checkpoint... 
Iteration: 988280125, states[0] = -86.896994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999484701, states[0] = -86.982990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010744088, states[0] = -86.855102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021797514, states[0] = -86.912432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033048556, states[0] = 12.974741, states[40]= 0.004811
Saving checkpoint... 
Iteration: 1044238883, states[0] = -86.847739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055330428, states[0] = -86.935309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066568801, states[0] = 4.297287, states[40]= 0.004564
Saving checkpoint... 
Iteration: 1077774570, states[0] = -86.891403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089022051, states[0] = 21.924677, states[40]= 0.007404
Saving checkpoint... 
Iteration: 1100241676, states[0] = -86.851682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111474323, states[0] = -86.981430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122669851, states[0] = -86.626099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133901912, states[0] = -86.965763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145148142, states[0] = -70.460498, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1156376411, states[0] = -86.957148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167603653, states[0] = -22.270378, states[40]= 0.000802
Saving checkpoint... 
Iteration: 1178729725, states[0] = -86.833859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189842837, states[0] = -86.942111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201093836, states[0] = -12.828350, states[40]= 0.001763
Saving checkpoint... 
Iteration: 1212362698, states[0] = -86.951552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223550328, states[0] = 12.273326, states[40]= 0.004799
Saving checkpoint... 
Iteration: 1234835974, states[0] = -86.938369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246092133, states[0] = -11.258007, states[40]= 0.002044
Saving checkpoint... 
Iteration: 1257341589, states[0] = -86.941408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268620720, states[0] = -38.850685, states[40]= 0.000143
Saving checkpoint... 
Iteration: 1279884862, states[0] = -86.960144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291177746, states[0] = -86.730799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302438868, states[0] = -86.974957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313718099, states[0] = -86.814657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324813361, states[0] = -86.924171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336031094, states[0] = 19.391056, states[40]= 0.005479
Saving checkpoint... 
Iteration: 1347267410, states[0] = -86.883626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358161436, states[0] = -85.477750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369422622, states[0] = -86.971213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380602284, states[0] = -20.944389, states[40]= 0.000875
Saving checkpoint... 
Iteration: 1391806079, states[0] = -86.918865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403019553, states[0] = 22.449422, states[40]= 0.008908
Saving checkpoint... 
Iteration: 1414252106, states[0] = -86.865447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425473109, states[0] = -86.981029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436711878, states[0] = -86.803641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447956062, states[0] = -86.978199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459180390, states[0] = -86.740439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470430401, states[0] = -86.972984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481487458, states[0] = -86.983026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492737477, states[0] = -86.845382, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.860449
 - CaMKt in component CaMK (millimolar): 0.006785
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.383194
 - nass in component intracellular_ions (millimolar): 6.383252
 - ki in component intracellular_ions (millimolar): 145.600303
 - kss in component intracellular_ions (millimolar): 145.600285
 - cansr in component intracellular_ions (millimolar): 1.295701
 - cajsr in component intracellular_ions (millimolar): 1.257647
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.008135
 - hf in component INa (dimensionless): 0.661759
 - hs in component INa (dimensionless): 0.661748
 - j in component INa (dimensionless): 0.661686
 - hsp in component INa (dimensionless): 0.413928
 - jp in component INa (dimensionless): 0.661643
 - mL in component INaL (dimensionless): 0.000228
 - hL in component INaL (dimensionless): 0.466424
 - hLp in component INaL (dimensionless): 0.240467
 - a in component Ito (dimensionless): 0.001072
 - iF in component Ito (dimensionless): 0.999467
 - iS in component Ito (dimensionless): 0.575633
 - ap in component Ito (dimensionless): 0.000546
 - iFp in component Ito (dimensionless): 0.999467
 - iSp in component Ito (dimensionless): 0.629396
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.932730
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999883
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001543
 - xrf in component IKr (dimensionless): 0.000009
 - xrs in component IKr (dimensionless): 0.414697
 - xs1 in component IKs (dimensionless): 0.247279
 - xs2 in component IKs (dimensionless): 0.000216
 - xk1 in component IK1 (dimensionless): 0.997016
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:47:17 (78571): called boinc_finish(0)

</stderr_txt>
]]>


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