𝕏

Task 55242128

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_4000-conf_592_0
Workunit 26234643
Created 28 Jun 2024, 6:17:14 UTC
Sent 29 Jun 2024, 8:10:39 UTC
Report deadline 2 Jul 2024, 8:10:39 UTC
Received 30 Jun 2024, 9:04:22 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222286
Run time 2 hours 52 min
CPU time 2 hours 2 min 53 sec
Validate state Valid
Credit 43.45
Device peak FLOPS 5.11 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.64 MB
Peak swap size 32.63 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_4000-conf_592.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_4000-conf_592_0_r1338158412_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_4000-conf_592_0_r1338158412_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.937560
     * GNaL_b in INaL: 0.005321
     * Gto_b in Ito: 0.076677
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031924
     * GKs_b in IKs: 0.001798
     * GK1_b in IK1: 0.157852
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 66.973685
     * GKb_b in IKb: 0.003756
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025260
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11368154, states[0] = -94.322691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23267638, states[0] = -94.263803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34158068, states[0] = -51.642490, states[40]= 0.000040
Saving checkpoint... 
Iteration: 44632772, states[0] = -94.257125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55172179, states[0] = -94.238894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65559406, states[0] = -94.229089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76002354, states[0] = 23.010985, states[40]= 1.739591
Saving checkpoint... 
Iteration: 86322942, states[0] = -94.083692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97146552, states[0] = -94.251194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109181147, states[0] = -94.252349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121138308, states[0] = -94.255952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131942601, states[0] = -94.236011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142776367, states[0] = -94.274073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153951236, states[0] = -94.237562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164788821, states[0] = -94.274828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174886612, states[0] = -94.270962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185326095, states[0] = -94.253118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196296344, states[0] = -94.027182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207555180, states[0] = -94.246783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219041333, states[0] = -94.264340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230506250, states[0] = -94.261669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241494519, states[0] = -94.248319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252342882, states[0] = -94.133892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263345301, states[0] = -94.252548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275272362, states[0] = -94.254883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286465367, states[0] = -94.247356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297083490, states[0] = -94.261994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308017643, states[0] = 24.712232, states[40]= -0.000000
Saving checkpoint... 
Iteration: 318503414, states[0] = -94.260183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329245922, states[0] = -94.255270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340351059, states[0] = -94.146479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351342113, states[0] = -94.251758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362524478, states[0] = -94.264769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374605064, states[0] = -94.274805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385395384, states[0] = -94.249717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396064852, states[0] = 20.867250, states[40]= 0.000001
Saving checkpoint... 
Iteration: 406461858, states[0] = -94.244510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417204298, states[0] = -94.255810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427973284, states[0] = -94.236553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439009392, states[0] = -94.263677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450225918, states[0] = -93.695704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461200673, states[0] = -94.255442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471185130, states[0] = -94.255920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482083521, states[0] = 12.833336, states[40]= 0.000016
Saving checkpoint... 
Iteration: 493001332, states[0] = -94.263424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504188967, states[0] = -92.627815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514521657, states[0] = -94.262430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525915724, states[0] = -94.236350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540785201, states[0] = -94.272500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551750624, states[0] = -94.239053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562845115, states[0] = -94.269798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573543627, states[0] = -94.243460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584331322, states[0] = -94.108908, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_4000-conf_592.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_4000-conf_592_0_r1338158412_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_4000-conf_592_0_r1338158412_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.937560
     * GNaL_b in INaL: 0.005321
     * Gto_b in Ito: 0.076677
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031924
     * GKs_b in IKs: 0.001798
     * GK1_b in IK1: 0.157852
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 66.973685
     * GKb_b in IKb: 0.003756
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025260
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 584331322
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.108908 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 598074299, states[0] = 17.122909, states[40]= 0.000005
Saving checkpoint... 
Iteration: 611318308, states[0] = -94.249557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624743076, states[0] = -94.272906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639268524, states[0] = -94.250928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652951203, states[0] = -94.263895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666727948, states[0] = -94.272804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678765380, states[0] = -94.271610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693199736, states[0] = -94.252812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709186338, states[0] = -94.253139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723513608, states[0] = -94.242505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737206832, states[0] = -94.252037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750297073, states[0] = -94.023725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762949828, states[0] = -94.262694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775582600, states[0] = -94.240168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788038704, states[0] = 26.828075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800429082, states[0] = -94.222252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812833644, states[0] = -94.267423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824639027, states[0] = -94.271125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837076820, states[0] = -94.256125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850148283, states[0] = -44.217532, states[40]= 0.000165
Saving checkpoint... 
Iteration: 862605708, states[0] = -94.269250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875249547, states[0] = -94.248884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889648670, states[0] = -94.237317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905871311, states[0] = -94.232727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921163031, states[0] = -94.251608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937570374, states[0] = -94.238602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952831945, states[0] = -94.265890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963602317, states[0] = -94.237533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975843264, states[0] = -94.232417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989355293, states[0] = -94.244012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002226885, states[0] = -93.695640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016495052, states[0] = -94.249791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032520707, states[0] = -94.256273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047974443, states[0] = -94.229397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063551208, states[0] = -94.237629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077381809, states[0] = -94.242175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090497257, states[0] = -94.249601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103115240, states[0] = -94.251449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115845847, states[0] = -94.230760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130968563, states[0] = -94.257599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145726928, states[0] = -94.232694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160813926, states[0] = -94.264260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175779646, states[0] = -94.231300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190809886, states[0] = -94.264081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206072309, states[0] = 17.971735, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1220673221, states[0] = -94.267066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235954957, states[0] = -94.227539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251067696, states[0] = -94.251764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265495218, states[0] = -94.236757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279627397, states[0] = -94.233310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293991237, states[0] = -94.226305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308142332, states[0] = -37.359976, states[40]= 0.000296
Saving checkpoint... 
Iteration: 1322671275, states[0] = -94.265888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336956077, states[0] = -94.255809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351356260, states[0] = -94.239816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365916923, states[0] = -94.226655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380088500, states[0] = 10.285414, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1395030444, states[0] = -94.251745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409416101, states[0] = -94.237322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424312939, states[0] = -94.058681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439603226, states[0] = -94.232033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454230141, states[0] = -93.711722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469494271, states[0] = -94.234435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483247992, states[0] = -94.241948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494721112, states[0] = -94.263447, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.099769
 - CaMKt in component CaMK (millimolar): 0.002332
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.196525
 - nass in component intracellular_ions (millimolar): 7.196661
 - ki in component intracellular_ions (millimolar): 144.483350
 - kss in component intracellular_ions (millimolar): 144.483335
 - cansr in component intracellular_ions (millimolar): 2.415009
 - cajsr in component intracellular_ions (millimolar): 2.415426
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003924
 - hf in component INa (dimensionless): 0.865370
 - hs in component INa (dimensionless): 0.865371
 - j in component INa (dimensionless): 0.865375
 - hsp in component INa (dimensionless): 0.698869
 - jp in component INa (dimensionless): 0.865377
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707543
 - hLp in component INaL (dimensionless): 0.513457
 - a in component Ito (dimensionless): 0.000658
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.999850
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999850
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996733
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005293
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.006787
 - xs1 in component IKs (dimensionless): 0.039537
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997540
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:12:04 (1199): called boinc_finish(0)

</stderr_txt>
]]>