𝕏

Task 55236681

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_ENDO_1000-conf_587_1
Workunit 26231922
Created 28 Jun 2024, 6:14:51 UTC
Sent 29 Jun 2024, 7:24:11 UTC
Report deadline 2 Jul 2024, 7:24:11 UTC
Received 1 Jul 2024, 16:19:46 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214494
Run time 2 hours 24 min 8 sec
CPU time 2 hours 10 min 31 sec
Validate state Valid
Credit 45.02
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.11 MB
Peak swap size 6.22 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_ENDO_1000-conf_587.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_ENDO_1000-conf_587_1_r1891267684_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_ENDO_1000-conf_587_1_r1891267684_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 107.623232
     * GNaL_b in INaL: 0.004915
     * Gto_b in Ito: 0.079580
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033449
     * GKs_b in IKs: 0.002111
     * GK1_b in IK1: 0.164354
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.174315
     * GKb_b in IKb: 0.003673
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037651
     * celltype in environment: 0.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10384575, states[0] = -94.374741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20845587, states[0] = -94.299371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31156172, states[0] = -62.403470, states[40]= 0.000024
Saving checkpoint... 
Iteration: 41634417, states[0] = -40.902790, states[40]= 0.000510
Saving checkpoint... 
Iteration: 51896614, states[0] = -94.359429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62271274, states[0] = -94.161395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72770455, states[0] = -94.162783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83271369, states[0] = -94.168406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93592159, states[0] = -0.604559, states[40]= 0.003196
Saving checkpoint... 
Iteration: 103963158, states[0] = -94.409858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114382450, states[0] = -94.364113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124707286, states[0] = -93.892646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135108979, states[0] = -16.661528, states[40]= 0.001453
Saving checkpoint... 
Iteration: 145582048, states[0] = 5.817681, states[40]= 0.002480
Saving checkpoint... 
Iteration: 155888010, states[0] = -94.370506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165965391, states[0] = -94.413431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176175818, states[0] = -90.027388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186553667, states[0] = 19.771719, states[40]= 0.000544
Saving checkpoint... 
Iteration: 196981227, states[0] = -94.418476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207394041, states[0] = -94.375419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217807366, states[0] = -94.263807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228208984, states[0] = -93.903654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238576347, states[0] = 8.937070, states[40]= 0.001952
Saving checkpoint... 
Iteration: 249028043, states[0] = 29.923703, states[40]= 0.000213
Saving checkpoint... 
Iteration: 259478572, states[0] = -94.417267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269864092, states[0] = -94.347639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280339044, states[0] = -94.316734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290667036, states[0] = -78.391945, states[40]= 0.000002
Saving checkpoint... 
Iteration: 301049069, states[0] = 21.774136, states[40]= 0.000403
Saving checkpoint... 
Iteration: 311477004, states[0] = -94.416308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321857383, states[0] = -94.339701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332035315, states[0] = 27.378761, states[40]= 0.000169
Saving checkpoint... 
Iteration: 342491494, states[0] = -94.420014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352953478, states[0] = -94.407719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363353480, states[0] = -94.334707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373768238, states[0] = -94.163558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384001718, states[0] = 48.722026, states[40]= 0.714887
Saving checkpoint... 
Iteration: 394227140, states[0] = -93.999730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404600908, states[0] = -8.309982, states[40]= 0.002577
Saving checkpoint... 
Iteration: 414988224, states[0] = -94.418457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425447328, states[0] = -94.404470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436003956, states[0] = 37.084890, states[40]= 0.490971
Saving checkpoint... 
Iteration: 446505297, states[0] = 33.816086, states[40]= 0.310773
Saving checkpoint... 
Iteration: 457034207, states[0] = 27.793100, states[40]= 0.000161
Saving checkpoint... 
Iteration: 467536916, states[0] = 26.768049, states[40]= 0.000183
Saving checkpoint... 
Iteration: 477931702, states[0] = -94.396661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488284398, states[0] = -94.208621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498763341, states[0] = -94.146530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509103772, states[0] = -11.216855, states[40]= 0.002124
Saving checkpoint... 
Iteration: 519490816, states[0] = -94.418097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529915154, states[0] = -94.386904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540269685, states[0] = -94.166387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550702199, states[0] = -93.858554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561148838, states[0] = -56.847526, states[40]= 0.000057
Saving checkpoint... 
Iteration: 571597540, states[0] = -5.138025, states[40]= 0.002987
Saving checkpoint... 
Iteration: 581935890, states[0] = -94.397715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592357059, states[0] = -94.336651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602650767, states[0] = -58.821638, states[40]= 0.000042
Saving checkpoint... 
Iteration: 612619828, states[0] = -27.830725, states[40]= 0.001292
Saving checkpoint... 
Iteration: 622829001, states[0] = -94.298397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633180555, states[0] = -92.633495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643614604, states[0] = -22.580414, states[40]= 0.001275
Saving checkpoint... 
Iteration: 654084796, states[0] = 4.172923, states[40]= 0.002720
Saving checkpoint... 
Iteration: 664497566, states[0] = -94.418315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674937690, states[0] = -94.397661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685376854, states[0] = -94.356274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695816425, states[0] = -94.276427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706250837, states[0] = -94.099927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716721791, states[0] = -93.969402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727030453, states[0] = 29.131398, states[40]= 0.000165
Saving checkpoint... 
Iteration: 737492217, states[0] = -94.416299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747798474, states[0] = -94.239884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758154721, states[0] = -62.962194, states[40]= 0.000022
Saving checkpoint... 
Iteration: 768597683, states[0] = -5.264054, states[40]= 0.002974
Saving checkpoint... 
Iteration: 779101734, states[0] = -9.127889, states[40]= 0.002452
Saving checkpoint... 
Iteration: 789554241, states[0] = 19.516392, states[40]= 0.000564
Saving checkpoint... 
Iteration: 800004177, states[0] = 36.359088, states[40]= 0.455610
Saving checkpoint... 
Iteration: 810449389, states[0] = -94.401537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820938459, states[0] = -94.396583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831268896, states[0] = -94.161033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841595222, states[0] = -3.145003, states[40]= 0.003134
Saving checkpoint... 
Iteration: 852068004, states[0] = 13.149640, states[40]= 0.001282
Saving checkpoint... 
Iteration: 862619514, states[0] = -27.515190, states[40]= 0.001298
Saving checkpoint... 
Iteration: 873090185, states[0] = 0.672537, states[40]= 0.003094
Saving checkpoint... 
Iteration: 883355530, states[0] = -94.331986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893720555, states[0] = -93.961156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904120034, states[0] = -28.031824, states[40]= 0.001287
Saving checkpoint... 
Iteration: 914588274, states[0] = 1.970964, states[40]= 0.002987
Saving checkpoint... 
Iteration: 925026899, states[0] = 30.280306, states[40]= 0.000262
Saving checkpoint... 
Iteration: 935485563, states[0] = -94.412608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945799630, states[0] = -94.240458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956195817, states[0] = -93.803703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966650260, states[0] = -58.293880, states[40]= 0.000045
Saving checkpoint... 
Iteration: 976942051, states[0] = -94.396702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987283621, states[0] = -94.201607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997727360, states[0] = -93.994722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008254340, states[0] = -94.110014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018772981, states[0] = -94.171567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029138866, states[0] = -46.741849, states[40]= 0.000239
Saving checkpoint... 
Iteration: 1039644729, states[0] = -52.670430, states[40]= 0.000105
Saving checkpoint... 
Iteration: 1050208289, states[0] = -93.891308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060575524, states[0] = 9.372850, states[40]= 0.001880
Saving checkpoint... 
Iteration: 1070828560, states[0] = -94.293251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081377660, states[0] = -94.353099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091969188, states[0] = -94.406136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102495487, states[0] = -94.413499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113053357, states[0] = 19.908414, states[40]= 0.000534
Saving checkpoint... 
Iteration: 1123568566, states[0] = 12.877621, states[40]= 0.001322
Saving checkpoint... 
Iteration: 1134155716, states[0] = -64.029675, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1144545602, states[0] = 23.252050, states[40]= 0.000321
Saving checkpoint... 
Iteration: 1155109019, states[0] = -16.757457, states[40]= 0.001442
Saving checkpoint... 
Iteration: 1165691102, states[0] = -93.731436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176214825, states[0] = -93.927378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186685265, states[0] = -93.455951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197209204, states[0] = -93.895197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207715690, states[0] = -93.931831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218297452, states[0] = -94.232915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228825869, states[0] = -94.287361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239401499, states[0] = -94.370881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249905227, states[0] = -94.373372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260471700, states[0] = -94.405292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270979815, states[0] = -94.407676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282326506, states[0] = -94.287864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294030769, states[0] = 29.025010, states[40]= 0.000162
Saving checkpoint... 
Iteration: 1305295028, states[0] = -94.226533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317568011, states[0] = 13.148291, states[40]= 0.001283
Saving checkpoint... 
Iteration: 1329114615, states[0] = -22.582998, states[40]= 0.001275
Saving checkpoint... 
Iteration: 1341235442, states[0] = -94.029416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353148192, states[0] = -56.175734, states[40]= 0.000063
Saving checkpoint... 
Iteration: 1364173075, states[0] = -87.105484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376710055, states[0] = -93.898332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388296971, states[0] = -94.230139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400136419, states[0] = -44.272505, states[40]= 0.000327
Saving checkpoint... 
Iteration: 1412127872, states[0] = -35.774963, states[40]= 0.000831
Saving checkpoint... 
Iteration: 1423668790, states[0] = -80.984778, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1436296482, states[0] = -94.228554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448101173, states[0] = -8.560173, states[40]= 0.002540
Saving checkpoint... 
Iteration: 1458734767, states[0] = -94.025167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470423696, states[0] = -94.382591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482439421, states[0] = -94.390499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494151503, states[0] = -59.564042, states[40]= 0.000037
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.286507
 - CaMKt in component CaMK (millimolar): 0.017470
 - cass in component intracellular_ions (millimolar): 0.000098
 - nai in component intracellular_ions (millimolar): 7.078973
 - nass in component intracellular_ions (millimolar): 7.079098
 - ki in component intracellular_ions (millimolar): 144.701042
 - kss in component intracellular_ions (millimolar): 144.701022
 - cansr in component intracellular_ions (millimolar): 1.945960
 - cajsr in component intracellular_ions (millimolar): 1.902790
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.003850
 - hf in component INa (dimensionless): 0.868907
 - hs in component INa (dimensionless): 0.868897
 - j in component INa (dimensionless): 0.868832
 - hsp in component INa (dimensionless): 0.705228
 - jp in component INa (dimensionless): 0.868786
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.689386
 - hLp in component INaL (dimensionless): 0.423016
 - a in component Ito (dimensionless): 0.000650
 - iF in component Ito (dimensionless): 0.999855
 - iS in component Ito (dimensionless): 0.603639
 - ap in component Ito (dimensionless): 0.000331
 - iFp in component Ito (dimensionless): 0.999855
 - iSp in component Ito (dimensionless): 0.670704
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.904516
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999785
 - jca in component ICaL (dimensionless): 0.999969
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004665
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.390814
 - xs1 in component IKs (dimensionless): 0.282779
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997495
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:19:32 (12000): called boinc_finish(0)

</stderr_txt>
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