𝕏

Task 55233932

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_1000-conf_184_1
Workunit 26230549
Created 28 Jun 2024, 6:13:37 UTC
Sent 29 Jun 2024, 7:03:24 UTC
Report deadline 2 Jul 2024, 7:03:24 UTC
Received 30 Jun 2024, 14:15:17 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 217692
Run time 2 hours 48 min 29 sec
CPU time 2 hours 46 min 50 sec
Validate state Valid
Credit 39.98
Device peak FLOPS 3.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.61 MB
Peak swap size 4.10 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_1000-conf_184.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_1000-conf_184_1_r887081611_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_1000-conf_184_1_r887081611_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 113.213412
     * GNaL_b in INaL: 0.005684
     * Gto_b in Ito: 0.094859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030129
     * GKs_b in IKs: 0.002076
     * GK1_b in IK1: 0.178261
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 74.047205
     * GKb_b in IKb: 0.003852
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019956
     * celltype in environment: 1.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9272796, states[0] = -94.644805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18523609, states[0] = 22.841882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27798795, states[0] = -94.641546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37486174, states[0] = -94.773484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46771659, states[0] = -94.596774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56037814, states[0] = 22.600600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65297968, states[0] = -94.677909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74561947, states[0] = 16.637237, states[40]= 0.000033
Saving checkpoint... 
Iteration: 83818955, states[0] = -94.725576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93056648, states[0] = 18.270820, states[40]= 0.000015
Saving checkpoint... 
Iteration: 102319874, states[0] = -94.733506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111586464, states[0] = 3.788004, states[40]= 0.001327
Saving checkpoint... 
Iteration: 120854537, states[0] = -94.775182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130087591, states[0] = 2.894414, states[40]= 0.001548
Saving checkpoint... 
Iteration: 139348345, states[0] = -94.770316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149090445, states[0] = 0.707928, states[40]= 0.002073
Saving checkpoint... 
Iteration: 158340323, states[0] = -94.761876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167607386, states[0] = -16.742284, states[40]= 0.002606
Saving checkpoint... 
Iteration: 176899001, states[0] = -94.803127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186125008, states[0] = -36.775985, states[40]= 0.003376
Saving checkpoint... 
Iteration: 195399311, states[0] = -94.801955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204656260, states[0] = -79.509988, states[40]= 0.000018
Saving checkpoint... 
Iteration: 213898145, states[0] = -94.799961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223146836, states[0] = -63.881841, states[40]= 0.000161
Saving checkpoint... 
Iteration: 232417972, states[0] = -94.806299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241694023, states[0] = -94.233395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250912084, states[0] = -94.802582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260140073, states[0] = -55.124322, states[40]= 0.000534
Saving checkpoint... 
Iteration: 269722568, states[0] = -94.431529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279140861, states[0] = -56.111630, states[40]= 0.000470
Saving checkpoint... 
Iteration: 288400542, states[0] = -94.794531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297699398, states[0] = -94.272544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306957847, states[0] = -94.809455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316259755, states[0] = -94.590359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325518141, states[0] = 21.327910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334764751, states[0] = -94.604616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344029036, states[0] = 22.449792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353308059, states[0] = -94.702449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362593951, states[0] = -2.290658, states[40]= 0.002725
Saving checkpoint... 
Iteration: 371879105, states[0] = -94.775778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381158918, states[0] = -84.792287, states[40]= 0.000008
Saving checkpoint... 
Iteration: 390443381, states[0] = -94.799185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400119696, states[0] = -30.733553, states[40]= 0.004163
Saving checkpoint... 
Iteration: 409207844, states[0] = -94.325382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418485357, states[0] = -94.802866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427748072, states[0] = -94.538103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437014634, states[0] = 20.554347, states[40]= -0.000000
Saving checkpoint... 
Iteration: 446245143, states[0] = -94.524698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455482381, states[0] = -94.799272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464702900, states[0] = -94.284190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473917099, states[0] = -94.784382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483138560, states[0] = -53.214075, states[40]= 0.000680
Saving checkpoint... 
Iteration: 492330810, states[0] = -94.722388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501552518, states[0] = 19.305745, states[40]= 0.000008
Saving checkpoint... 
Iteration: 510783370, states[0] = -94.639005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520007400, states[0] = 17.633002, states[40]= 0.000002
Saving checkpoint... 
Iteration: 529633337, states[0] = -46.743915, states[40]= 0.001437
Saving checkpoint... 
Iteration: 538854482, states[0] = -94.742667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548137385, states[0] = -51.746104, states[40]= 0.000815
Saving checkpoint... 
Iteration: 557405243, states[0] = -94.772403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566688189, states[0] = -94.151097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575874917, states[0] = -94.754804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585113495, states[0] = -23.757763, states[40]= 0.003332
Saving checkpoint... 
Iteration: 594327113, states[0] = -94.708610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603543300, states[0] = 21.381591, states[40]= 0.000001
Saving checkpoint... 
Iteration: 612783774, states[0] = -94.630741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621964419, states[0] = -94.782238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631219483, states[0] = -94.380437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640470563, states[0] = -94.781419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649729845, states[0] = -94.435979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659252442, states[0] = -94.533671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668464534, states[0] = -94.778102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677737521, states[0] = -94.470602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686961058, states[0] = -94.775935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696237112, states[0] = -94.467047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705481317, states[0] = -94.776802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714737271, states[0] = -94.466105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723976496, states[0] = -94.774659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733190757, states[0] = -94.159223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742428355, states[0] = -94.763918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751664465, states[0] = -92.009802, states[40]= 0.000002
Saving checkpoint... 
Iteration: 760916884, states[0] = -94.758659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770136150, states[0] = -50.195846, states[40]= 0.000975
Saving checkpoint... 
Iteration: 779363313, states[0] = -94.728387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789018765, states[0] = 21.450795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798249438, states[0] = -94.509783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807521559, states[0] = 21.883263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816781313, states[0] = -94.606474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826108878, states[0] = -18.475882, states[40]= 0.002612
Saving checkpoint... 
Iteration: 835343616, states[0] = -94.705851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844555957, states[0] = 18.292159, states[40]= 0.000015
Saving checkpoint... 
Iteration: 853786788, states[0] = -94.615948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862994386, states[0] = -94.763791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872224983, states[0] = -94.389908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881412182, states[0] = -94.746126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890636598, states[0] = -50.738518, states[40]= 0.000913
Saving checkpoint... 
Iteration: 899871161, states[0] = -94.723253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908954286, states[0] = -94.754940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918467806, states[0] = -94.756213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927703012, states[0] = -94.242448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936937702, states[0] = -94.748951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946138382, states[0] = -52.947089, states[40]= 0.000699
Saving checkpoint... 
Iteration: 955302288, states[0] = -94.638167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964513763, states[0] = 20.329244, states[40]= 0.000001
Saving checkpoint... 
Iteration: 973700888, states[0] = -94.221912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982947177, states[0] = -94.746956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992159611, states[0] = -85.904729, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1001337727, states[0] = -94.684682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010536553, states[0] = 22.241590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019744040, states[0] = -94.468006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028986554, states[0] = -94.748355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038602075, states[0] = -10.581170, states[40]= 0.003005
Saving checkpoint... 
Iteration: 1047751917, states[0] = -94.496491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057002479, states[0] = 17.531929, states[40]= 2.750435
Saving checkpoint... 
Iteration: 1066247660, states[0] = -94.478473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075465630, states[0] = -94.741879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084687744, states[0] = -94.098974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093841822, states[0] = -94.680782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103074493, states[0] = 10.621898, states[40]= 0.000303
Saving checkpoint... 
Iteration: 1112284686, states[0] = -94.587866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121503297, states[0] = 11.627741, states[40]= 2.068530
Saving checkpoint... 
Iteration: 1130718390, states[0] = -94.328263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139977408, states[0] = -94.737614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149190596, states[0] = -94.119459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158445883, states[0] = -94.731026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168040038, states[0] = 21.882704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177280630, states[0] = -94.572255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186496676, states[0] = -94.735016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195704787, states[0] = -94.231122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204944813, states[0] = -94.726624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214162857, states[0] = -90.557014, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1223356436, states[0] = -94.682967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232586757, states[0] = 3.409077, states[40]= 0.001436
Saving checkpoint... 
Iteration: 1241779531, states[0] = -94.563672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250999634, states[0] = -94.729418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260190513, states[0] = -94.108378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269423314, states[0] = -94.715206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278669233, states[0] = -93.549826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287890650, states[0] = -94.700191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297486853, states[0] = -94.724376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306693092, states[0] = -94.126971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315926626, states[0] = -94.712054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325173783, states[0] = -93.874548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334419280, states[0] = -94.708091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343671307, states[0] = -93.750476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352900143, states[0] = -94.698977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362144581, states[0] = -60.736877, states[40]= 0.000247
Saving checkpoint... 
Iteration: 1371352082, states[0] = -94.665846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380598316, states[0] = -6.439543, states[40]= 0.003115
Saving checkpoint... 
Iteration: 1389791131, states[0] = -94.577098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398989849, states[0] = -94.715536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408236439, states[0] = -94.399135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417323908, states[0] = -94.630455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427664643, states[0] = -91.997876, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1436913809, states[0] = -94.697016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446119513, states[0] = -30.437769, states[40]= 0.004103
Saving checkpoint... 
Iteration: 1455316042, states[0] = -94.615878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464522640, states[0] = 22.032881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473683002, states[0] = -94.015844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482896927, states[0] = -94.685898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492055586, states[0] = 18.432515, states[40]= 0.000013
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.583092
 - CaMKt in component CaMK (millimolar): 0.029775
 - cass in component intracellular_ions (millimolar): 0.000109
 - nai in component intracellular_ions (millimolar): 7.808650
 - nass in component intracellular_ions (millimolar): 7.808832
 - ki in component intracellular_ions (millimolar): 143.064690
 - kss in component intracellular_ions (millimolar): 143.064650
 - cansr in component intracellular_ions (millimolar): 3.362369
 - cajsr in component intracellular_ions (millimolar): 3.342852
 - cai in component intracellular_ions (millimolar): 0.000114
 - m in component INa (dimensionless): 0.003737
 - hf in component INa (dimensionless): 0.874359
 - hs in component INa (dimensionless): 0.874357
 - j in component INa (dimensionless): 0.874335
 - hsp in component INa (dimensionless): 0.715297
 - jp in component INa (dimensionless): 0.874316
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.700583
 - hLp in component INaL (dimensionless): 0.440127
 - a in component Ito (dimensionless): 0.000637
 - iF in component Ito (dimensionless): 0.999862
 - iS in component Ito (dimensionless): 0.999862
 - ap in component Ito (dimensionless): 0.000325
 - iFp in component Ito (dimensionless): 0.999862
 - iSp in component Ito (dimensionless): 0.999862
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.917119
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999861
 - jca in component ICaL (dimensionless): 0.999971
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.007106
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.322899
 - xs1 in component IKs (dimensionless): 0.275624
 - xs2 in component IKs (dimensionless): 0.000091
 - xk1 in component IK1 (dimensionless): 0.997420
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:14:58 (92586): called boinc_finish(0)

</stderr_txt>
]]>


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