𝕏

Task 55233479

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_575-conf_383_0
Workunit 26230324
Created 28 Jun 2024, 6:13:26 UTC
Sent 29 Jun 2024, 7:03:24 UTC
Report deadline 2 Jul 2024, 7:03:34 UTC
Received 30 Jun 2024, 5:47:52 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 217692
Run time 2 hours 47 min 6 sec
CPU time 2 hours 44 min 57 sec
Validate state Valid
Credit 40.38
Device peak FLOPS 3.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.73 MB
Peak swap size 4.10 GB
Peak disk usage 0.21 MB

Stderr output

<core_client_version>7.24.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_575-conf_383.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_575-conf_383_0_r650351967_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_575-conf_383_0_r650351967_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000350.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 91.636921
     * GNaL_b in INaL: 0.005618
     * Gto_b in Ito: 0.092585
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032916
     * GKs_b in IKs: 0.001827
     * GK1_b in IK1: 0.177773
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 69.660024
     * GKb_b in IKb: 0.003892
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.039960
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 5218.000000
     * CL_0 in membrane: 575.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499887500.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9420015, states[0] = -84.645083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18829861, states[0] = -77.848015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28226272, states[0] = 17.020932, states[40]= 0.000012
Saving checkpoint... 
Iteration: 37655990, states[0] = -84.816756, states[40]= 0.000001
Saving checkpoint... 
Iteration: 46996893, states[0] = -67.617610, states[40]= 0.000002
Saving checkpoint... 
Iteration: 56360997, states[0] = 30.430280, states[40]= 0.045061
Saving checkpoint... 
Iteration: 65802688, states[0] = -84.755694, states[40]= 0.000001
Saving checkpoint... 
Iteration: 75232685, states[0] = -84.475699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84651145, states[0] = -57.239125, states[40]= 0.000007
Saving checkpoint... 
Iteration: 94063212, states[0] = 17.067202, states[40]= 0.000008
Saving checkpoint... 
Iteration: 103940249, states[0] = -83.791228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113365447, states[0] = -14.727264, states[40]= 0.000105
Saving checkpoint... 
Iteration: 122819527, states[0] = 13.454920, states[40]= 0.000017
Saving checkpoint... 
Iteration: 132235573, states[0] = -84.820226, states[40]= 0.000001
Saving checkpoint... 
Iteration: 141643130, states[0] = -84.465645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151083076, states[0] = -81.879552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160508532, states[0] = -6.587338, states[40]= 0.000132
Saving checkpoint... 
Iteration: 169940605, states[0] = 27.937854, states[40]= 0.000095
Saving checkpoint... 
Iteration: 179338360, states[0] = -84.657762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 188760222, states[0] = -84.139960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198167348, states[0] = -2.848152, states[40]= 0.000121
Saving checkpoint... 
Iteration: 207598857, states[0] = 29.449203, states[40]= 0.000434
Saving checkpoint... 
Iteration: 217202990, states[0] = -77.371994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226963275, states[0] = -57.037584, states[40]= 0.000007
Saving checkpoint... 
Iteration: 236438080, states[0] = -41.809694, states[40]= 0.000041
Saving checkpoint... 
Iteration: 245898183, states[0] = -9.019781, states[40]= 0.000128
Saving checkpoint... 
Iteration: 255353856, states[0] = 15.273593, states[40]= 0.000011
Saving checkpoint... 
Iteration: 264777671, states[0] = -84.828074, states[40]= 0.000001
Saving checkpoint... 
Iteration: 274163796, states[0] = -84.325721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283535404, states[0] = 11.416044, states[40]= 0.000024
Saving checkpoint... 
Iteration: 292919550, states[0] = -84.731285, states[40]= 0.000001
Saving checkpoint... 
Iteration: 302297479, states[0] = -69.632640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 311708318, states[0] = 12.676328, states[40]= 0.000019
Saving checkpoint... 
Iteration: 321124841, states[0] = -84.819728, states[40]= 0.000001
Saving checkpoint... 
Iteration: 330534809, states[0] = -84.490062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339922347, states[0] = -23.305403, states[40]= 0.000087
Saving checkpoint... 
Iteration: 349705802, states[0] = -33.333389, states[40]= 0.000076
Saving checkpoint... 
Iteration: 359090793, states[0] = 31.150921, states[40]= 0.704875
Saving checkpoint... 
Iteration: 368504812, states[0] = -84.609713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 377948839, states[0] = -84.299892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387401939, states[0] = -76.017876, states[40]= 0.000001
Saving checkpoint... 
Iteration: 396829224, states[0] = -2.261287, states[40]= 0.000118
Saving checkpoint... 
Iteration: 406231601, states[0] = -84.832501, states[40]= 0.000001
Saving checkpoint... 
Iteration: 415639692, states[0] = -84.519963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425043590, states[0] = -48.274465, states[40]= 0.000021
Saving checkpoint... 
Iteration: 434449972, states[0] = 23.831994, states[40]= 0.000005
Saving checkpoint... 
Iteration: 443839028, states[0] = -84.652828, states[40]= 0.000001
Saving checkpoint... 
Iteration: 453254526, states[0] = -83.928317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462694607, states[0] = -34.851506, states[40]= 0.000070
Saving checkpoint... 
Iteration: 472436590, states[0] = 2.089464, states[40]= 0.000086
Saving checkpoint... 
Iteration: 481846099, states[0] = -84.834460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 491312505, states[0] = -84.782475, states[40]= 0.000001
Saving checkpoint... 
Iteration: 500755599, states[0] = -84.609688, states[40]= 0.000001
Saving checkpoint... 
Iteration: 510194393, states[0] = -84.252334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519576958, states[0] = 8.873476, states[40]= 0.000036
Saving checkpoint... 
Iteration: 529001502, states[0] = 34.678615, states[40]= 1.096405
Saving checkpoint... 
Iteration: 538385157, states[0] = -84.392798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547772588, states[0] = -8.322930, states[40]= 0.000130
Saving checkpoint... 
Iteration: 557186153, states[0] = 30.414925, states[40]= 0.042690
Saving checkpoint... 
Iteration: 566524305, states[0] = -83.257230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575925444, states[0] = 9.841532, states[40]= 0.000031
Saving checkpoint... 
Iteration: 585292668, states[0] = -84.664839, states[40]= 0.000001
Saving checkpoint... 
Iteration: 595141860, states[0] = 30.947931, states[40]= 0.005375
Saving checkpoint... 
Iteration: 604562173, states[0] = -84.693610, states[40]= 0.000001
Saving checkpoint... 
Iteration: 614056536, states[0] = -84.719456, states[40]= 0.000001
Saving checkpoint... 
Iteration: 623483587, states[0] = -84.377328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632881307, states[0] = -18.960947, states[40]= 0.000090
Saving checkpoint... 
Iteration: 642312870, states[0] = 23.644591, states[40]= 0.000004
Saving checkpoint... 
Iteration: 651717891, states[0] = -84.714095, states[40]= 0.000001
Saving checkpoint... 
Iteration: 661121989, states[0] = -84.108894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670511945, states[0] = 10.470171, states[40]= 0.000028
Saving checkpoint... 
Iteration: 679911278, states[0] = -84.773152, states[40]= 0.000001
Saving checkpoint... 
Iteration: 689263770, states[0] = -57.636146, states[40]= 0.000007
Saving checkpoint... 
Iteration: 698527736, states[0] = -84.427369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707813150, states[0] = -84.809709, states[40]= 0.000001
Saving checkpoint... 
Iteration: 717599065, states[0] = -84.833355, states[40]= 0.000001
Saving checkpoint... 
Iteration: 726752961, states[0] = -84.702645, states[40]= 0.000001
Saving checkpoint... 
Iteration: 736026135, states[0] = 28.682477, states[40]= 0.000192
Saving checkpoint... 
Iteration: 745316312, states[0] = -45.567039, states[40]= 0.000028
Saving checkpoint... 
Iteration: 754594036, states[0] = -84.453630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763850637, states[0] = -84.737720, states[40]= 0.000001
Saving checkpoint... 
Iteration: 773111858, states[0] = 29.294324, states[40]= 0.000362
Saving checkpoint... 
Iteration: 782366755, states[0] = -2.278946, states[40]= 0.000118
Saving checkpoint... 
Iteration: 791636073, states[0] = -83.060193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800901183, states[0] = -84.576612, states[40]= 0.000001
Saving checkpoint... 
Iteration: 810153330, states[0] = -84.781774, states[40]= 0.000001
Saving checkpoint... 
Iteration: 819436994, states[0] = 10.441885, states[40]= 0.000028
Saving checkpoint... 
Iteration: 829177510, states[0] = 28.173373, states[40]= 0.000118
Saving checkpoint... 
Iteration: 838439409, states[0] = -13.488465, states[40]= 0.000110
Saving checkpoint... 
Iteration: 847740938, states[0] = -84.427933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857046035, states[0] = 29.457512, states[40]= 0.110341
Saving checkpoint... 
Iteration: 866322957, states[0] = -8.734593, states[40]= 0.000129
Saving checkpoint... 
Iteration: 875628306, states[0] = -84.426062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884898334, states[0] = -84.765531, states[40]= 0.000001
Saving checkpoint... 
Iteration: 894169216, states[0] = 20.493600, states[40]= 0.000004
Saving checkpoint... 
Iteration: 903469160, states[0] = -80.926606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912718239, states[0] = -84.442869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922012560, states[0] = -77.424320, states[40]= 0.000001
Saving checkpoint... 
Iteration: 931279247, states[0] = 7.376408, states[40]= 0.000045
Saving checkpoint... 
Iteration: 940520676, states[0] = -36.074398, states[40]= 0.000065
Saving checkpoint... 
Iteration: 949742178, states[0] = -62.070713, states[40]= 0.000004
Saving checkpoint... 
Iteration: 959371969, states[0] = -84.793035, states[40]= 0.000001
Saving checkpoint... 
Iteration: 968636729, states[0] = 17.848520, states[40]= 0.000007
Saving checkpoint... 
Iteration: 977904106, states[0] = -45.900803, states[40]= 0.000027
Saving checkpoint... 
Iteration: 987193419, states[0] = -84.525476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996459660, states[0] = -84.792362, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1005756122, states[0] = -4.062463, states[40]= 0.000127
Saving checkpoint... 
Iteration: 1015015480, states[0] = -77.279909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024312681, states[0] = -84.682571, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1033610198, states[0] = 18.671734, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1042878511, states[0] = -45.198141, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1052152864, states[0] = -84.417151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061455167, states[0] = 28.764094, states[40]= 0.367079
Saving checkpoint... 
Iteration: 1070753945, states[0] = -31.124789, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1080103945, states[0] = -84.738642, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1089605545, states[0] = -84.779014, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1098906984, states[0] = -4.930316, states[40]= 0.000129
Saving checkpoint... 
Iteration: 1108175420, states[0] = -83.456384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117486015, states[0] = -84.758852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1126758980, states[0] = 19.318138, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1136026413, states[0] = -42.738260, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1145277689, states[0] = -84.185235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154546816, states[0] = -84.664847, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1163826803, states[0] = 28.443514, states[40]= 0.000151
Saving checkpoint... 
Iteration: 1173055791, states[0] = 14.174917, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1182308365, states[0] = -36.283073, states[40]= 0.000064
Saving checkpoint... 
Iteration: 1191553453, states[0] = -83.824102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200824280, states[0] = -84.618624, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1210648813, states[0] = -84.789790, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1219776011, states[0] = -84.486955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229091283, states[0] = 27.681306, states[40]= 0.000075
Saving checkpoint... 
Iteration: 1238403638, states[0] = -78.037686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247705937, states[0] = -84.697584, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1256947713, states[0] = -84.813944, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1266229325, states[0] = -2.329910, states[40]= 0.000119
Saving checkpoint... 
Iteration: 1275478048, states[0] = -59.885260, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1284722246, states[0] = -84.255863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294041345, states[0] = 30.056122, states[40]= 0.582126
Saving checkpoint... 
Iteration: 1303277373, states[0] = 22.681958, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1312564048, states[0] = -57.947907, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1321902055, states[0] = -84.762477, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1331214713, states[0] = -13.843321, states[40]= 0.000108
Saving checkpoint... 
Iteration: 1340865339, states[0] = -84.727022, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1350030436, states[0] = -84.582262, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1359328563, states[0] = 27.770341, states[40]= 0.000081
Saving checkpoint... 
Iteration: 1368616551, states[0] = -45.815888, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1377916582, states[0] = -84.574255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1387206473, states[0] = 30.688665, states[40]= 0.002504
Saving checkpoint... 
Iteration: 1396480385, states[0] = -17.784302, states[40]= 0.000092
Saving checkpoint... 
Iteration: 1405719865, states[0] = -65.745801, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1414984620, states[0] = -84.454558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424226970, states[0] = -84.677144, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1433500835, states[0] = 28.798234, states[40]= 0.000214
Saving checkpoint... 
Iteration: 1442784830, states[0] = -37.973787, states[40]= 0.000056
Saving checkpoint... 
Iteration: 1452055488, states[0] = -84.325046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461326906, states[0] = -84.720261, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1470983865, states[0] = -67.891578, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1480250800, states[0] = -84.477363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489540320, states[0] = 32.253391, states[40]= 0.827997
Saving checkpoint... 
Iteration: 1498858109, states[0] = -50.623853, states[40]= 0.000016
Total time: 3000350.000000
State Variables:
 - v in component membrane (millivolt): -84.686910
 - CaMKt in component CaMK (millimolar): 0.058403
 - cass in component intracellular_ions (millimolar): 0.000111
 - nai in component intracellular_ions (millimolar): 6.972871
 - nass in component intracellular_ions (millimolar): 6.973046
 - ki in component intracellular_ions (millimolar): 144.588101
 - kss in component intracellular_ions (millimolar): 144.588070
 - cansr in component intracellular_ions (millimolar): 2.241529
 - cajsr in component intracellular_ions (millimolar): 1.835290
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.010118
 - hf in component INa (dimensionless): 0.577862
 - hs in component INa (dimensionless): 0.577645
 - j in component INa (dimensionless): 0.576417
 - hsp in component INa (dimensionless): 0.330118
 - jp in component INa (dimensionless): 0.575081
 - mL in component INaL (dimensionless): 0.000345
 - hL in component INaL (dimensionless): 0.327525
 - hLp in component INaL (dimensionless): 0.141062
 - a in component Ito (dimensionless): 0.001241
 - iF in component Ito (dimensionless): 0.999220
 - iS in component Ito (dimensionless): 0.310532
 - ap in component Ito (dimensionless): 0.000633
 - iFp in component Ito (dimensionless): 0.999220
 - iSp in component Ito (dimensionless): 0.342921
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.817619
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.991068
 - jca in component ICaL (dimensionless): 0.994611
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.007745
 - xrf in component IKr (dimensionless): 0.001687
 - xrs in component IKr (dimensionless): 0.718175
 - xs1 in component IKs (dimensionless): 0.420198
 - xs2 in component IKs (dimensionless): 0.000283
 - xk1 in component IK1 (dimensionless): 0.996756
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
22:02:14 (91932): called boinc_finish(0)

</stderr_txt>
]]>