𝕏

Task 55232847

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_883_0
Workunit 26230008
Created 28 Jun 2024, 6:13:10 UTC
Sent 29 Jun 2024, 7:03:24 UTC
Report deadline 2 Jul 2024, 9:56:12 UTC
Received 30 Jun 2024, 23:09:41 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 217692
Run time 2 hours 49 min 8 sec
CPU time 2 hours 47 min 41 sec
Validate state Valid
Credit 44.20
Device peak FLOPS 3.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.69 MB
Peak swap size 4.10 GB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>7.24.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_883.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_883_0_r454072296_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_883_0_r454072296_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 114.252856
     * GNaL_b in INaL: 0.004807
     * Gto_b in Ito: 0.094810
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033163
     * GKs_b in IKs: 0.002113
     * GK1_b in IK1: 0.148394
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 72.353130
     * GKb_b in IKb: 0.003691
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.052387
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9293994, states[0] = -94.797793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18590953, states[0] = -8.435559, states[40]= 0.002943
Saving checkpoint... 
Iteration: 27893671, states[0] = -94.815963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37190542, states[0] = -94.372653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46446927, states[0] = -94.824732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55749306, states[0] = -94.591434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65040256, states[0] = 20.378203, states[40]= 0.002322
Saving checkpoint... 
Iteration: 74336788, states[0] = -94.745694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83658951, states[0] = -83.734551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93111225, states[0] = -28.480434, states[40]= 0.000902
Saving checkpoint... 
Iteration: 102566154, states[0] = 9.465705, states[40]= 0.004231
Saving checkpoint... 
Iteration: 111859105, states[0] = -94.763829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121181993, states[0] = -94.273516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130486656, states[0] = -94.824210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139747511, states[0] = -94.577452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149033866, states[0] = 22.666271, states[40]= 0.001984
Saving checkpoint... 
Iteration: 158255528, states[0] = -94.599228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167505698, states[0] = 28.538437, states[40]= 0.206738
Saving checkpoint... 
Iteration: 176814379, states[0] = -94.713079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186099172, states[0] = -15.650326, states[40]= 0.001616
Saving checkpoint... 
Iteration: 195416109, states[0] = -94.799211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204711471, states[0] = -94.449564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214002408, states[0] = 41.855756, states[40]= 0.447106
Saving checkpoint... 
Iteration: 223992487, states[0] = -94.824321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232907783, states[0] = -94.794821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242262071, states[0] = -94.615215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251555534, states[0] = 14.383001, states[40]= 0.003473
Saving checkpoint... 
Iteration: 260872960, states[0] = -94.772849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270188217, states[0] = -94.334862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279453418, states[0] = -94.813637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288742032, states[0] = -94.559928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298019804, states[0] = 26.251382, states[40]= 0.003159
Saving checkpoint... 
Iteration: 307311637, states[0] = -94.708537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316575680, states[0] = 4.321897, states[40]= 0.004619
Saving checkpoint... 
Iteration: 325868527, states[0] = -94.769209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335200419, states[0] = -94.399957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344475278, states[0] = -94.819758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354228647, states[0] = -94.515485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363503205, states[0] = 36.469144, states[40]= 0.423207
Saving checkpoint... 
Iteration: 372836005, states[0] = -94.738800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382134430, states[0] = -52.937531, states[40]= 0.000049
Saving checkpoint... 
Iteration: 391437912, states[0] = -94.807727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400763600, states[0] = -94.618314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410055215, states[0] = 14.520280, states[40]= 0.003448
Saving checkpoint... 
Iteration: 419363909, states[0] = -94.765165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428598992, states[0] = -15.450033, states[40]= 0.001644
Saving checkpoint... 
Iteration: 437917334, states[0] = -94.798774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447194082, states[0] = -94.368513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456514552, states[0] = 26.704769, states[40]= 0.011657
Saving checkpoint... 
Iteration: 465863981, states[0] = -94.765052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475175721, states[0] = -94.055381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484842362, states[0] = -94.745130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494130939, states[0] = -49.150991, states[40]= 0.000087
Saving checkpoint... 
Iteration: 503475749, states[0] = -94.819292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512820764, states[0] = -94.720137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522124998, states[0] = -42.755576, states[40]= 0.000215
Saving checkpoint... 
Iteration: 531464379, states[0] = -94.816075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540783173, states[0] = -94.660216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550089314, states[0] = -5.653464, states[40]= 0.003612
Saving checkpoint... 
Iteration: 559393516, states[0] = -94.785555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568695361, states[0] = -94.374598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578019612, states[0] = 26.279688, states[40]= 0.003271
Saving checkpoint... 
Iteration: 587309332, states[0] = -94.704175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596627966, states[0] = -45.936717, states[40]= 0.000139
Saving checkpoint... 
Iteration: 606046590, states[0] = 18.044903, states[40]= 0.002779
Saving checkpoint... 
Iteration: 615194888, states[0] = -94.372025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624523988, states[0] = 25.467513, states[40]= 0.001971
Saving checkpoint... 
Iteration: 633792527, states[0] = -94.677119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643062371, states[0] = 11.321544, states[40]= 0.003988
Saving checkpoint... 
Iteration: 652358801, states[0] = -94.760004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661654846, states[0] = -77.298980, states[40]= 0.000001
Saving checkpoint... 
Iteration: 670917704, states[0] = -94.798088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680157925, states[0] = -81.902206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689495707, states[0] = -94.823230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698812779, states[0] = -94.708695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708141270, states[0] = -60.394222, states[40]= 0.000015
Saving checkpoint... 
Iteration: 717429166, states[0] = -94.803016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726769665, states[0] = -94.631246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736133790, states[0] = -52.241449, states[40]= 0.000055
Saving checkpoint... 
Iteration: 745072157, states[0] = 6.350554, states[40]= 0.004531
Saving checkpoint... 
Iteration: 754417346, states[0] = -94.797611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763732330, states[0] = -94.526756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773052815, states[0] = 15.534025, states[40]= 0.003259
Saving checkpoint... 
Iteration: 782365421, states[0] = -94.765052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791641364, states[0] = -60.497639, states[40]= 0.000014
Saving checkpoint... 
Iteration: 801014782, states[0] = 26.699561, states[40]= 0.010882
Saving checkpoint... 
Iteration: 810453152, states[0] = -94.811581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819856749, states[0] = -94.757592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829224158, states[0] = -94.497408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838636833, states[0] = -55.543115, states[40]= 0.000032
Saving checkpoint... 
Iteration: 847970030, states[0] = -94.816501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857645690, states[0] = -65.391245, states[40]= 0.000006
Saving checkpoint... 
Iteration: 867083710, states[0] = -1.028486, states[40]= 0.004383
Saving checkpoint... 
Iteration: 876515720, states[0] = 26.663229, states[40]= 0.008285
Saving checkpoint... 
Iteration: 885938289, states[0] = -94.806045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895361529, states[0] = -94.761429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904764882, states[0] = -94.619507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914168518, states[0] = -92.718166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923542913, states[0] = 19.456896, states[40]= 0.002516
Saving checkpoint... 
Iteration: 932945813, states[0] = -94.808634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942321648, states[0] = -94.719679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951729928, states[0] = -94.517758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961134678, states[0] = -53.203607, states[40]= 0.000047
Saving checkpoint... 
Iteration: 970548402, states[0] = 17.330560, states[40]= 0.002915
Saving checkpoint... 
Iteration: 980159874, states[0] = -84.771158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989703515, states[0] = -94.411749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999143895, states[0] = -63.327888, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1008577725, states[0] = 3.069184, states[40]= 0.004627
Saving checkpoint... 
Iteration: 1017999742, states[0] = -94.822837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027391554, states[0] = -94.782628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036780874, states[0] = -94.653853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046186899, states[0] = -94.322229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055595924, states[0] = -12.184573, states[40]= 0.002191
Saving checkpoint... 
Iteration: 1065008538, states[0] = 26.776217, states[40]= 0.080898
Saving checkpoint... 
Iteration: 1074422461, states[0] = -94.798788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083859401, states[0] = -94.758925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093288236, states[0] = -94.667719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102829492, states[0] = -94.728699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112679096, states[0] = -94.204507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124201390, states[0] = -94.401507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135784105, states[0] = -94.659804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147311184, states[0] = -94.704771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158807595, states[0] = -94.699497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170269209, states[0] = -94.628564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181750411, states[0] = -94.581125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193298274, states[0] = -94.684794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204889941, states[0] = -94.780970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216515517, states[0] = 26.673372, states[40]= 0.008779
Saving checkpoint... 
Iteration: 1228088429, states[0] = -4.861520, states[40]= 0.003774
Saving checkpoint... 
Iteration: 1239624562, states[0] = -42.288225, states[40]= 0.000229
Saving checkpoint... 
Iteration: 1252124432, states[0] = -42.149911, states[40]= 0.000233
Saving checkpoint... 
Iteration: 1263343231, states[0] = -94.743135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274808931, states[0] = -94.701038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286284719, states[0] = -94.660420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297867369, states[0] = -94.764701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309389820, states[0] = -94.780508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320908192, states[0] = -94.790975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332367004, states[0] = -94.764284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343895633, states[0] = -94.783922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355474136, states[0] = -94.815729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367031466, states[0] = 23.440742, states[40]= 0.001886
Saving checkpoint... 
Iteration: 1378560027, states[0] = 12.402795, states[40]= 0.003819
Saving checkpoint... 
Iteration: 1390098164, states[0] = -14.560450, states[40]= 0.001774
Saving checkpoint... 
Iteration: 1401634062, states[0] = -52.533155, states[40]= 0.000052
Saving checkpoint... 
Iteration: 1415443899, states[0] = -94.806170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431361262, states[0] = -94.759222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447235088, states[0] = -94.533462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463009708, states[0] = 26.673203, states[40]= 0.054877
Saving checkpoint... 
Iteration: 1478986274, states[0] = -94.818256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494837139, states[0] = -94.735881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510551953, states[0] = 11.834867, states[40]= 0.005212
Saving checkpoint... 
Iteration: 1526198187, states[0] = -94.845716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541768289, states[0] = -94.445545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1557383444, states[0] = -94.514234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572970600, states[0] = -94.564227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1588474350, states[0] = -94.456380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1603982160, states[0] = -94.422762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1619472326, states[0] = -94.338399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1634896297, states[0] = -94.316605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650306933, states[0] = -94.120098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1665815681, states[0] = -94.318932, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.166897
 - CaMKt in component CaMK (millimolar): 0.001108
 - cass in component intracellular_ions (millimolar): 0.000086
 - nai in component intracellular_ions (millimolar): 6.305834
 - nass in component intracellular_ions (millimolar): 6.305919
 - ki in component intracellular_ions (millimolar): 145.594873
 - kss in component intracellular_ions (millimolar): 145.594862
 - cansr in component intracellular_ions (millimolar): 1.557366
 - cajsr in component intracellular_ions (millimolar): 1.557401
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.003897
 - hf in component INa (dimensionless): 0.866650
 - hs in component INa (dimensionless): 0.866650
 - j in component INa (dimensionless): 0.866652
 - hsp in component INa (dimensionless): 0.701182
 - jp in component INa (dimensionless): 0.866652
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709364
 - hLp in component INaL (dimensionless): 0.516014
 - a in component Ito (dimensionless): 0.000655
 - iF in component Ito (dimensionless): 0.999852
 - iS in component Ito (dimensionless): 0.997758
 - ap in component Ito (dimensionless): 0.000334
 - iFp in component Ito (dimensionless): 0.999852
 - iSp in component Ito (dimensionless): 0.999251
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998936
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002933
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001799
 - xs1 in component IKs (dimensionless): 0.021855
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997524
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:50:13 (93316): called boinc_finish(0)

</stderr_txt>
]]>


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