𝕏

Task 55231565

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_581_0
Workunit 26229367
Created 28 Jun 2024, 6:12:38 UTC
Sent 29 Jun 2024, 6:46:12 UTC
Report deadline 2 Jul 2024, 16:22:12 UTC
Received 30 Jun 2024, 1:09:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227233
Run time 3 hours 7 min 26 sec
CPU time 1 hours 52 min 44 sec
Validate state Valid
Credit 56.55
Device peak FLOPS 3.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.39 MB
Peak swap size 391.72 GB
Peak disk usage 0.47 MB

Stderr output

<core_client_version>7.20.7</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_581.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_581_0_r1688154283_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_581_0_r1688154283_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 113.646992
     * GNaL_b in INaL: 0.004825
     * Gto_b in Ito: 0.081128
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032896
     * GKs_b in IKs: 0.001796
     * GK1_b in IK1: 0.158346
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 66.332817
     * GKb_b in IKb: 0.003740
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.048964
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15642172, states[0] = -80.383304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31590880, states[0] = -18.356311, states[40]= 0.001089
Saving checkpoint... 
Iteration: 47721499, states[0] = -94.955448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63572589, states[0] = -1.448640, states[40]= 0.004093
Saving checkpoint... 
Iteration: 79537132, states[0] = 15.123544, states[40]= 0.005656
Saving checkpoint... 
Iteration: 95862442, states[0] = -95.054316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111644656, states[0] = -77.565691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127969999, states[0] = -95.076680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144077568, states[0] = -4.366414, states[40]= 0.003557
Saving checkpoint... 
Iteration: 160615417, states[0] = -41.381546, states[40]= 0.000094
Saving checkpoint... 
Iteration: 176363172, states[0] = -95.049216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192416942, states[0] = -95.065034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207872598, states[0] = -95.052271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223561982, states[0] = 4.743245, states[40]= 0.004763
Saving checkpoint... 
Iteration: 247689296, states[0] = -94.872502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263672727, states[0] = -94.824589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279358217, states[0] = -95.046657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295159132, states[0] = -93.950147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311190509, states[0] = -94.874874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327549529, states[0] = 10.296773, states[40]= 0.005081
Saving checkpoint... 
Iteration: 343566738, states[0] = 2.355464, states[40]= 0.004565
Saving checkpoint... 
Iteration: 359495197, states[0] = -95.077318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375536582, states[0] = 15.462673, states[40]= 0.005701
Saving checkpoint... 
Iteration: 391973711, states[0] = -95.074671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408165111, states[0] = -94.681415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424401499, states[0] = -95.060712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440322530, states[0] = -95.029555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456396778, states[0] = -95.059415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472539992, states[0] = 14.157887, states[40]= 0.005460
Saving checkpoint... 
Iteration: 488472024, states[0] = -95.074389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504122160, states[0] = -48.648252, states[40]= 0.000030
Saving checkpoint... 
Iteration: 519960091, states[0] = -95.072638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535990609, states[0] = -95.076705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551745545, states[0] = -94.964034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567390954, states[0] = -95.057697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583161173, states[0] = -94.346843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599571118, states[0] = -0.082073, states[40]= 0.004281
Saving checkpoint... 
Iteration: 615236500, states[0] = -94.952352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630991458, states[0] = -95.076752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646778417, states[0] = -94.998250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662798971, states[0] = -95.014495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678647044, states[0] = -81.156372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694883758, states[0] = -95.055450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710767082, states[0] = -94.987685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726393455, states[0] = -95.058336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741708615, states[0] = -94.909002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757998546, states[0] = -95.077467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774208884, states[0] = -94.909459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790111227, states[0] = -36.919673, states[40]= 0.000179
Saving checkpoint... 
Iteration: 805768816, states[0] = -94.989326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821554839, states[0] = 8.020564, states[40]= 0.004955
Saving checkpoint... 
Iteration: 837376125, states[0] = -95.052896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853382451, states[0] = -95.054954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869131002, states[0] = -58.668452, states[40]= 0.000006
Saving checkpoint... 
Iteration: 884974269, states[0] = -95.074485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900803217, states[0] = -95.017327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916728455, states[0] = -94.940890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932779552, states[0] = -94.999087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948939872, states[0] = -95.068992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964843742, states[0] = -95.040069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980352028, states[0] = -95.043710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996217603, states[0] = -94.924100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012693693, states[0] = -94.880873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029314543, states[0] = -95.024563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045547165, states[0] = 11.279592, states[40]= 0.005149
Saving checkpoint... 
Iteration: 1061966750, states[0] = -95.073343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078433331, states[0] = -95.067672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094746759, states[0] = -94.965228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111175848, states[0] = -94.838971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127823148, states[0] = -95.029538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144501176, states[0] = 50.633277, states[40]= 0.031597
Saving checkpoint... 
Iteration: 1160909104, states[0] = -95.062270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177425675, states[0] = -95.066055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193797367, states[0] = -95.013063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210081173, states[0] = -7.115456, states[40]= 0.002979
Saving checkpoint... 
Iteration: 1226483307, states[0] = -95.075469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242826974, states[0] = -95.031579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259100744, states[0] = -26.181510, states[40]= 0.000596
Saving checkpoint... 
Iteration: 1275820297, states[0] = -95.027841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292097313, states[0] = -22.694133, states[40]= 0.000772
Saving checkpoint... 
Iteration: 1308698327, states[0] = -94.889751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325363989, states[0] = -95.048310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341693969, states[0] = -94.881244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358286299, states[0] = -95.004509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374950356, states[0] = -95.070620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391382521, states[0] = -95.054692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407800339, states[0] = -95.015067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423996131, states[0] = -95.076854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440131132, states[0] = -58.819549, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1457005335, states[0] = 28.381122, states[40]= 0.131375
Saving checkpoint... 
Iteration: 1473500039, states[0] = -90.259790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490265774, states[0] = -94.985975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506784756, states[0] = -95.182815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1522975597, states[0] = -95.178849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539197738, states[0] = -95.236972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556173050, states[0] = -12.398042, states[40]= 0.002132
Saving checkpoint... 
Iteration: 1572711803, states[0] = -59.053651, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1588601965, states[0] = -46.801110, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1604588642, states[0] = -95.240430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1622307444, states[0] = -95.274902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640613340, states[0] = -95.284714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659169008, states[0] = -95.200417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674763540, states[0] = -95.187108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1691141444, states[0] = 10.637707, states[40]= 0.006083
Saving checkpoint... 
Iteration: 1707126573, states[0] = -82.771220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723377737, states[0] = -95.220804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1739566663, states[0] = -95.195187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1755494561, states[0] = -95.254553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1771903192, states[0] = -48.641161, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1790375584, states[0] = -95.352438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1809211864, states[0] = -94.964283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827613670, states[0] = -41.728326, states[40]= 0.000089
Saving checkpoint... 
Iteration: 1846257432, states[0] = -94.996914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867114272, states[0] = -40.830341, states[40]= 0.000102
Saving checkpoint... 
Iteration: 1888170556, states[0] = -94.815437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1909132159, states[0] = -60.290154, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1929851075, states[0] = -95.044569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1950754314, states[0] = -94.974571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971391549, states[0] = -95.057641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1992165194, states[0] = -94.685413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013014034, states[0] = 22.075039, states[40]= 0.023567
Saving checkpoint... 
Iteration: 2034129916, states[0] = -57.415630, states[40]= 0.000007
Saving checkpoint... 
Iteration: 2054860646, states[0] = -95.046650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079543361, states[0] = 12.825210, states[40]= 0.005288
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.952758
 - CaMKt in component CaMK (millimolar): 0.006472
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.636523
 - nass in component intracellular_ions (millimolar): 6.636582
 - ki in component intracellular_ions (millimolar): 145.348051
 - kss in component intracellular_ions (millimolar): 145.348032
 - cansr in component intracellular_ions (millimolar): 1.284399
 - cajsr in component intracellular_ions (millimolar): 1.247699
 - cai in component intracellular_ions (millimolar): 0.000073
 - m in component INa (dimensionless): 0.003600
 - hf in component INa (dimensionless): 0.880881
 - hs in component INa (dimensionless): 0.880877
 - j in component INa (dimensionless): 0.880851
 - hsp in component INa (dimensionless): 0.727494
 - jp in component INa (dimensionless): 0.880834
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.713073
 - hLp in component INaL (dimensionless): 0.459043
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.629712
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.706294
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940565
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999903
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001500
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.326448
 - xs1 in component IKs (dimensionless): 0.228821
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997324
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:30:15 (57395): called boinc_finish(0)

</stderr_txt>
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