𝕏

Task 55226845

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_333-conf_676_0
Workunit 26227009
Created 28 Jun 2024, 6:10:30 UTC
Sent 29 Jun 2024, 6:12:50 UTC
Report deadline 2 Jul 2024, 6:12:50 UTC
Received 30 Jun 2024, 10:28:54 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214039
Run time 1 hours 6 min 26 sec
CPU time 35 min 12 sec
Validate state Valid
Credit 43.84
Device peak FLOPS 3.77 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.74 MB
Peak swap size 5.30 MB
Peak disk usage 0.12 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_333-conf_676.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_333-conf_676_0_r766490973_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_333-conf_676_0_r766490973_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 98.770860
     * GNaL_b in INaL: 0.004998
     * Gto_b in Ito: 0.088544
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033480
     * GKs_b in IKs: 0.002139
     * GK1_b in IK1: 0.173751
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 73.548253
     * GKb_b in IKb: 0.003822
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.042593
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 15236298, states[0] = -34.786364, states[40]= 0.000270
Saving checkpoint... 
Iteration: 31006291, states[0] = 22.107894, states[40]= 0.052713
Saving checkpoint... 
Iteration: 46433023, states[0] = -85.231643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57356532, states[0] = 12.987098, states[40]= 0.008126
Saving checkpoint... 
Iteration: 73420312, states[0] = -70.091064, states[40]= 0.000002
Saving checkpoint... 
Iteration: 89125896, states[0] = -87.798040, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_333-conf_676.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_333-conf_676_0_r766490973_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_333-conf_676_0_r766490973_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 98.770860
     * GNaL_b in INaL: 0.004998
     * Gto_b in Ito: 0.088544
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033480
     * GKs_b in IKs: 0.002139
     * GK1_b in IK1: 0.173751
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 73.548253
     * GKb_b in IKb: 0.003822
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.042593
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 89125896
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -87.798040 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 100000499, states[0] = 21.604507, states[40]= 0.042124
Saving checkpoint... 
Iteration: 116291828, states[0] = -87.805674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131888603, states[0] = -30.626768, states[40]= 0.000466
Saving checkpoint... 
Iteration: 148181446, states[0] = 12.563513, states[40]= 0.008023
Saving checkpoint... 
Iteration: 164565422, states[0] = -50.046883, states[40]= 0.000036
Saving checkpoint... 
Iteration: 176226021, states[0] = -42.887166, states[40]= 0.000102
Saving checkpoint... 
Iteration: 193577066, states[0] = -74.056597, states[40]= 0.000001
Saving checkpoint... 
Iteration: 210965134, states[0] = -87.857692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228976564, states[0] = -87.892228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246700942, states[0] = -16.672416, states[40]= 0.001724
Saving checkpoint... 
Iteration: 264848716, states[0] = 3.694099, states[40]= 0.006613
Saving checkpoint... 
Iteration: 282328891, states[0] = 15.900735, states[40]= 0.009297
Saving checkpoint... 
Iteration: 299939761, states[0] = -87.804403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312124482, states[0] = -87.865481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330143818, states[0] = 21.746249, states[40]= 0.045079
Saving checkpoint... 
Iteration: 347619541, states[0] = -87.861560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365472153, states[0] = 22.487957, states[40]= 0.061130
Saving checkpoint... 
Iteration: 382931579, states[0] = -87.804666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400579731, states[0] = -87.721698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418289024, states[0] = -87.887311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435921187, states[0] = -87.785215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453756519, states[0] = -87.799743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471296805, states[0] = 21.557754, states[40]= 0.041225
Saving checkpoint... 
Iteration: 489186145, states[0] = -30.551180, states[40]= 0.000470
Saving checkpoint... 
Iteration: 507095487, states[0] = -87.837180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525290677, states[0] = 21.878781, states[40]= 0.047872
Saving checkpoint... 
Iteration: 543241020, states[0] = -87.773699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562061528, states[0] = -87.697681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580263836, states[0] = -87.863792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597896156, states[0] = -87.743104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616037179, states[0] = -78.351181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631483556, states[0] = -0.796815, states[40]= 0.005773
Saving checkpoint... 
Iteration: 647804136, states[0] = 8.576794, states[40]= 0.007319
Saving checkpoint... 
Iteration: 664049324, states[0] = -87.660061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675071775, states[0] = -87.814133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690656836, states[0] = -17.108198, states[40]= 0.001652
Saving checkpoint... 
Iteration: 706171162, states[0] = -40.208623, states[40]= 0.000147
Saving checkpoint... 
Iteration: 720856722, states[0] = -72.294819, states[40]= 0.000001
Saving checkpoint... 
Iteration: 736586684, states[0] = -87.877273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747380148, states[0] = -87.735732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762803161, states[0] = -0.199221, states[40]= 0.005903
Saving checkpoint... 
Iteration: 778475478, states[0] = -8.630634, states[40]= 0.003642
Saving checkpoint... 
Iteration: 794510001, states[0] = -61.727993, states[40]= 0.000006
Saving checkpoint... 
Iteration: 810841812, states[0] = -61.909628, states[40]= 0.000006
Saving checkpoint... 
Iteration: 827670244, states[0] = -56.795258, states[40]= 0.000013
Saving checkpoint... 
Iteration: 844804972, states[0] = -12.542992, states[40]= 0.002583
Saving checkpoint... 
Iteration: 862570524, states[0] = -87.867690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879981735, states[0] = -32.485688, states[40]= 0.000382
Saving checkpoint... 
Iteration: 897542289, states[0] = -87.787008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914134323, states[0] = -16.864768, states[40]= 0.001692
Saving checkpoint... 
Iteration: 926121892, states[0] = -1.983961, states[40]= 0.005497
Saving checkpoint... 
Iteration: 943062548, states[0] = -87.867787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953725220, states[0] = -87.859678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969325257, states[0] = -60.762194, states[40]= 0.000007
Saving checkpoint... 
Iteration: 985022057, states[0] = -87.727788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001241464, states[0] = 22.760190, states[40]= 0.066941
Saving checkpoint... 
Iteration: 1018193554, states[0] = -87.773164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031351349, states[0] = -87.732417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049193977, states[0] = -87.787556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067078792, states[0] = 18.306563, states[40]= 0.012305
Saving checkpoint... 
Iteration: 1084351619, states[0] = -87.764335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102225653, states[0] = 35.400578, states[40]= 0.100659
Saving checkpoint... 
Iteration: 1119537103, states[0] = -87.845387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137193861, states[0] = -87.819198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155231525, states[0] = 20.361397, states[40]= 0.023064
Saving checkpoint... 
Iteration: 1173547960, states[0] = -87.889183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191505177, states[0] = -87.752301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198585462, states[0] = 6.289047, states[40]= 0.006996
Saving checkpoint... 
Iteration: 1216627566, states[0] = -51.076736, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1234762747, states[0] = -8.054963, states[40]= 0.003810
Saving checkpoint... 
Iteration: 1252769890, states[0] = -20.961269, states[40]= 0.001142
Saving checkpoint... 
Iteration: 1270240645, states[0] = 9.451321, states[40]= 0.007449
Saving checkpoint... 
Iteration: 1288186453, states[0] = -87.843743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305395919, states[0] = 14.426722, states[40]= 0.008570
Saving checkpoint... 
Iteration: 1322732991, states[0] = 11.071279, states[40]= 0.007717
Saving checkpoint... 
Iteration: 1340447601, states[0] = -49.714046, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1358058760, states[0] = 13.584939, states[40]= 0.008291
Saving checkpoint... 
Iteration: 1375920465, states[0] = -15.378462, states[40]= 0.001960
Saving checkpoint... 
Iteration: 1394169015, states[0] = -87.821679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412301750, states[0] = -87.250045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430530257, states[0] = 24.117804, states[40]= 0.091664
Saving checkpoint... 
Iteration: 1448683533, states[0] = -87.879928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466009854, states[0] = -87.866050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485304428, states[0] = -87.718805, states[40]= 0.000000
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.767501
 - CaMKt in component CaMK (millimolar): 0.040058
 - cass in component intracellular_ions (millimolar): 0.000115
 - nai in component intracellular_ions (millimolar): 6.914926
 - nass in component intracellular_ions (millimolar): 6.915073
 - ki in component intracellular_ions (millimolar): 145.010426
 - kss in component intracellular_ions (millimolar): 145.010392
 - cansr in component intracellular_ions (millimolar): 1.595150
 - cajsr in component intracellular_ions (millimolar): 1.174757
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.007426
 - hf in component INa (dimensionless): 0.694281
 - hs in component INa (dimensionless): 0.694067
 - j in component INa (dimensionless): 0.685695
 - hsp in component INa (dimensionless): 0.449616
 - jp in component INa (dimensionless): 0.662635
 - mL in component INaL (dimensionless): 0.000192
 - hL in component INaL (dimensionless): 0.306340
 - hLp in component INaL (dimensionless): 0.144339
 - a in component Ito (dimensionless): 0.001009
 - iF in component Ito (dimensionless): 0.999545
 - iS in component Ito (dimensionless): 0.182633
 - ap in component Ito (dimensionless): 0.000514
 - iFp in component Ito (dimensionless): 0.999545
 - iSp in component Ito (dimensionless): 0.222824
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.814790
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.969829
 - jca in component ICaL (dimensionless): 0.951297
 - ffp in component ICaL (dimensionless): 0.999902
 - fcafp in component ICaL (dimensionless): 0.999993
 - nca in component ICaL (dimensionless): 0.009154
 - xrf in component IKr (dimensionless): 0.023532
 - xrs in component IKr (dimensionless): 0.770639
 - xs1 in component IKs (dimensionless): 0.447750
 - xs2 in component IKs (dimensionless): 0.000939
 - xk1 in component IK1 (dimensionless): 0.996793
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:57:45 (32484): called boinc_finish(0)

</stderr_txt>
]]>


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